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Taftrio Tablet is an antiretroviral medicine used in the treatment of HIV. It contains Bictegravir, Emtricitabine and Tenofovir. It works by inhibiting the HIV reverse transcriptase enzymes necessary for the virus's DNA reproduction. This causes inhibition of DNA replication and thereby prevents further spread of infection. This medicine helps reduce the symptoms, control the infection, and prevent opportunistic infections effectively. It also helps in improving the quality of life of a patient with HIV.

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Written By Lakshmithulasi Yarragunta ,
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Manufacturer/Marketer :

Hetero Healthcare Pvt Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Taftrio Tablet

Taftrio Tablet is an antiretroviral medicine used in the treatment of HIV. Human Immunodeficiency Virus (HIV) is a retroviral infection that attacks and damages the cells of the immune system. This weakens the ability to fight against infections and diseases. If this condition is left untreated, it can lead to Acquired Immuno Deficiency Syndrome (AIDS).

Taftrio Tablet contains Bictegravir, Emtricitabine and Tenofovir as key ingredients. It works by inhibiting the HIV reverse transcriptase enzymes necessary for the virus's DNA reproduction.

Taftrio Tablet may cause side effects such as nausea, headache, abdominal pain, loss of appetite, vomiting, fatigue, diarrhoea, myalgia (muscle pain), skin rash and other allergic reactions. If these side effects persist, please consult your doctor. Taftrio Tablet should be taken as advised by your doctor.

Taftrio Tablet should be avoided if you are allergic to it. This medicine is contraindicated in patients with Hepatitis B infection and severe hepatic impairment. Before taking this medicine, inform your doctor if you have liver/kidney disease, hypersensitivity reactions, Stevens-Johnson syndrome, toxic epidermal necrolysis, cirrhosis, or hepatic fibrosis. If you are pregnant and breastfeeding, let your doctor know before taking Taftrio Tablet . Taftrio Tablet should be used in children only if recommended by the doctor.

Uses of Taftrio Tablet

Taftrio Tablet is used in the treatment of Human Immunodeficiency Virus (HIV) Infection. The detailed uses of Taftrio Tablet are as follows:

  • Treatment of HIV-1 infection in adults and adolescents: Taftrio Tablet is used for managing HIV-1 infection in adults and children weighing 25 kg or more, either as a first-line antiretroviral therapy or as a replacement for a stable regimen in patients with no history of treatment failure.
  • Suppression of viral replication: Taftrio Tablet works by preventing the virus from multiplying in the body, helping to reduce the viral load to undetectable levels.
  • Improvement of immune function: By controlling the virus, Taftrio Tablet allows the immune system to recover and function more effectively, reducing the risk of HIV-related complications.

Key Benefits

Taftrio Tablet is a combination of Bictegravir, Emtricitabine and Tenofovir. It works by inhibiting the HIV reverse transcriptase enzymes necessary for the virus's DNA reproduction. This causes inhibition of DNA replication and thereby prevents further spread of infection. Taftrio Tablet helps reduce the symptoms, control the infection, and prevent opportunistic infections effectively. It also helps in improving the quality of life of a patient with HIV. 

Side effects of Taftrio Tablet
  • Skin hyperpigmentation may make you feel conscious. Therefore, follow a healthy, balanced diet that provides the required nutrition for your skin.
  • Apply sunscreen or photoprotection agent with good SPF to prevent the darkening of the skin.
  • You can try chemical peels after consulting your doctor and checking the skin's suitability before applying them.
  • Pigmentation can be removed through laser or light therapy as well.
  • Skin bleaching products like glutathione can help in reducing skin darkening. Use them only if prescribed by your dermatologist/skin doctor.
  • To help reduce symptoms, eat foods high in vitamin C, such as oranges, bell peppers and strawberries.
  • Lightly blow your nose to remove mucus; steer clear of blowing hard.
  • Infections can be prevented from spreading by washing hands frequently and staying away from other people.
  • If you have allergies, do your best to avoid triggering allergens that could contribute to a runny nose.
  • Don't smoke, as irritating the nasal passages can make a runny nose worse.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
Managing depression as a side effect of medication: a comprehensive guide.
  • Remember, managing depression as a side effect of medication requires patience, persistence, and collaboration with your healthcare team.
  • Tell your doctor about your depression symptoms to adjust medication.
  • Consult a therapist or counsel for emotional support.
  • Engage in regular exercise to release endorphins (neurotransmitters).
  • Practice stress-reducing techniques like meditation and deep breathing.
  • Build a support network of friends, family, and support groups.
  • Establish a consistent sleep schedule.
  • Eat a nutritious diet rich in fruits, vegetables, and whole grains.
  • Limit or avoid alcohol and recreational substances.
  • Keep a mood journal to track symptoms and progress.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.

Directions for Use

  • Take Taftrio Tablet with or without food or as advised by a doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication, to ensure the safety.
  • Swallow the medicine as a whole with a glass of water.
  • Do not crush, break, or chew it.

How Taftrio Tablet Works

Taftrio Tablet contains Bictegravir, Emtricitabine and Tenofovir as key ingredients. It works by inhibiting the HIV reverse transcriptase enzymes necessary for the virus's DNA reproduction.
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Alcohol

Unsafe

Avoid alcohol consumption while on treatment with Taftrio Tablet . Alcohol intake might increase the risk of stomach or intestine bleeding.

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Pregnancy

Caution

If you are pregnant or suspect you may be pregnant, inform your doctor before taking Taftrio Tablet . Your doctor will prescribe a suitable dose of this medicine to prevent maternal-fetal HIV transmission.

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Breast Feeding

Unsafe

Taftrio Tablet is excreted in milk. If you have HIV or are taking Taftrio Tablet , you should not breastfeed your baby.

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Driving

Unsafe

Avoid driving vehicles or operating machines after taking Taftrio Tablet as it may cause fatigue.

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Liver

Caution

Taftrio Tablet can result in serious, sometimes fatal, liver damage. Inform your doctor if you have or have had a liver illness, particularly hepatitis B or C. Your doctor will most likely advise you not to take Taftrio Tablet .

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Kidney

Caution

Before using Taftrio Tablet , inform your doctor if you have or have ever had kidney disease, particularly if you are on dialysis treatment.

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Children

Consult your doctor

Please consult your doctor. Your doctor will decide the dose of this medicine based on the age and condition of your child.

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Heart

Caution

Exercise caution before using Taftrio Tablet in case of heart problems. Please consult your doctor if you have any concerns.

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Geriatrics

Safe if prescribed

Taftrio Tablet is generally safe for elderly patients. However, please consult your doctor if you have any concerns.

What if I have taken an overdose of Taftrio Tablet

Never take more than the prescribed dose. If you suspect that you or someone else might have taken an overdose of Taftrio Tablet , go to the accident and emergency department of your local hospital at once. Do this even if there are no signs of discomfort or poisoning. In case of overdose, patients must be closely monitored for signs or symptoms of adverse reactions and appropriate symptomatic treatment instituted.

Diet & Lifestyle Advise

  • Eat a healthy and balanced diet. Eat vitamin and nutrient-rich food such as vegetables and fruit as it helps to boost your immune system. Try to take lean protein and whole grains.
  • Avoid eating raw meat and eggs. Consume properly boiled and cooked meat, poultry or seafood.
  • Eat bland and low-fat foods, and avoid spicy or oily foods if you experience nausea or vomiting.
  • Get tested for other sexually transmitted infections, such as gonorrhoea or syphilis.
  • Try to reduce emotional and physical stress by spending time with your family or doing whatever makes you happy.
  • Drink more fluids and avoid alcoholic beverages to prevent dehydration.  
  • Never share personal items with body fluids or blood on them, such as razor blades or toothbrushes.
  • Avoid sharing used needles, other injection or drug equipment.

Have a query?

How Soon It Starts Working

The time required for Taftrio Tablet to start to work: The time required for Taftrio Tablet to show its action is unknown. The time for which the effects of Taftrio Tablet last: The duration of action for Taftrio Tablet is unknown.

What if you forget to take Taftrio Tablet

If you miss a dose of Taftrio Tablet , take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.

Storage

• Store in a cool and dry place away from sunlight. • Keep Taftrio Tablet out of the sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Drug Warnings

Taftrio Tablet should be avoided if you are allergic to it. This medicine is contraindicated in patients with severe hepatic impairment, hepatitis B infection and a combination of other HIV medicines. Inform your doctor about your medical history and the medicines you take to prevent possible interactions. Taftrio Tablet is known you cause fatal or non-fatal hepatotoxicity and skin disorders. Hence, careful monitoring should be done during the first 18 weeks of the treatment initiation. If the patient develops any signs or symptoms of hepatitis, increased transaminase, rash, or hypersensitivity reactions, Taftrio Tablet should be discontinued immediately. This medicine may cause dizziness; hence, avoid driving or operating machines while taking Taftrio Tablet . Before taking this medicine, inform your doctor if you have liver/kidney diseases, hypersensitivity reactions, Stevens-Johnson syndrome, cirrhosis, or hepatic fibrosis. If pregnant and breastfeeding, inform your doctor before taking Taftrio Tablet . Taftrio Tablet should be used in children only if recommended by the doctor. If prescribed, the child should be carefully monitored for any changes. Taftrio Tablet treats the infection but does not cure or prevent it.

Drug-Drug Interactions

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Drug-Drug Interactions: Taftrio Tablet may interact with contraceptives (ethyl estradiol, norethindrone), anti-viral drugs (adefovir dipivoxil, atazanavir, lamivudine), anti-Tb drug (rifampicin), ulcer medicine (sucralfate), antibiotics (azithromycin, clarithromycin, rifabutin), immunosuppressants (cyclosporine), anti-epileptics (phenobarbital or phenytoin), antacids, iron supplements and vitamins.

Drug-Food Interactions: Avoid smoking and alcohol consumption.

Drug-Disease Interactions: Inform your doctor if you have moderate to severe hepatic impairment, Stevens-Johnson syndrome, cirrhosis, hepatic fibrosis, and other skin disorders before starting treatment with Taftrio Tablet .

Tenofovir alafenamide + EmtricitabineCidofovir
Critical
Tenofovir alafenamide + EmtricitabineLamivudine
Critical

Drug-Drug Interactions

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Tenofovir alafenamide + EmtricitabineCidofovir
Critical
How does the drug interact with Taftrio Tablet:
Taking Cidofovir with Taftrio Tablet may increase the risk of kidney problems.

How to manage the interaction:
Although taking Cidofovir with Taftrio Tablet can result in an interaction, it can be taken if prescribed by a doctor. However, if you experience symptoms such as nausea, vomiting, loss of hunger, increased or decreased urine, swelling in hands or legs, shortness of breath, muscle pain, tiredness, weakness, confusion, or slow or rapid heart rate, consult a doctor. Do not discontinue any medication without consulting a doctor.
Tenofovir alafenamide + EmtricitabineLamivudine
Critical
How does the drug interact with Taftrio Tablet:
Combining Taftrio Tablet with Lamivudine may significantly reduce the blood levels of both the medications.

How to manage the interaction:
Although there is a possibility of interaction between Taftrio Tablet and Lamivudine, it can be taken if prescribed by a doctor. In case you experience any unusual symptoms, consult a doctor. Do not stop using any medications without a doctor's advice.
Tenofovir alafenamide + EmtricitabineAdefovir dipivoxil
Severe
How does the drug interact with Taftrio Tablet:
Taking Adefovir dipivoxil with Taftrio Tablet may increase the risk of kidney problems.

How to manage the interaction:
Although taking Adefovir dipivoxil with Taftrio Tablet can result in an interaction, it can be taken if prescribed by a doctor. However, if you experience symptoms such as nausea, vomiting, loss of hunger, increased or decreased urine, swelling in hands or legs, shortness of breath, muscle pain, tiredness, weakness, confusion, or slow or rapid heart rate, consult a doctor. Do not discontinue any medication without consulting a doctor.
Tenofovir alafenamide + EmtricitabineDeferasirox
Severe
How does the drug interact with Taftrio Tablet:
Taking Deferasirox with Taftrio Tablet may increase the risk of kidney problems.

How to manage the interaction:
Although taking Deferasirox with Taftrio Tablet can result in an interaction, it can be taken if prescribed by a doctor. However, if you experience symptoms such as nausea, vomiting, loss of hunger, increased or decreased urine, swelling in hands or legs, shortness of breath, muscle pain, tiredness, weakness, confusion, or slow or rapid heart rate, consult a doctor. Do not discontinue any medication without consulting a doctor.
Tenofovir alafenamide + EmtricitabinePenicillamine
Severe
How does the drug interact with Taftrio Tablet:
Taking Penicillamine with Taftrio Tablet may increase the risk of kidney problems.

How to manage the interaction:
Although taking Penicillamine with Taftrio Tablet can result in an interaction, it can be taken if prescribed by a doctor. However, if you experience symptoms such as nausea, vomiting, loss of hunger, increased or decreased urine, swelling in hands or legs, shortness of breath, muscle pain, tiredness, weakness, confusion, or slow or rapid heart rate, consult a doctor. Do not discontinue any medication without consulting a doctor.
Tenofovir alafenamide + EmtricitabineRifabutin
Severe
How does the drug interact with Taftrio Tablet:
Combining Taftrio Tablet with Rifabutin may significantly reduce the blood levels of Taftrio Tablet.

How to manage the interaction:
Although there is a possibility of interaction between Taftrio Tablet and Rifabutin, it can be taken if prescribed by a doctor. In case you experience any unusual symptoms, consult a doctor. Do not stop using any medications without a doctor's advice.
Tenofovir alafenamide + EmtricitabineMesalazine
Severe
How does the drug interact with Taftrio Tablet:
Taking Mesalazine with Taftrio Tablet may increase the risk of kidney problems.

How to manage the interaction:
Although taking Mesalazine with Taftrio Tablet can result in an interaction, it can be taken if prescribed by a doctor. However, if you experience symptoms such as nausea, vomiting, loss of hunger, increased or decreased urine, swelling in hands or legs, shortness of breath, muscle pain, tiredness, weakness, confusion, or slow or rapid heart rate, consult a doctor. Do not discontinue any medication without consulting a doctor.
Tenofovir alafenamide + EmtricitabineEtodolac
Severe
How does the drug interact with Taftrio Tablet:
Taking Etodolac with Taftrio Tablet may increase the risk of kidney problems.

How to manage the interaction:
Although taking Etodolac with Taftrio Tablet can result in an interaction, it can be taken if prescribed by a doctor. However, if you experience symptoms such as nausea, vomiting, loss of hunger, increased or decreased urine, swelling in hands or legs, shortness of breath, muscle pain, tiredness, weakness, confusion, or slow or rapid heart rate, consult a doctor. Do not discontinue any medication without consulting a doctor.
Tenofovir alafenamide + EmtricitabineHuman immunoglobulin
Severe
How does the drug interact with Taftrio Tablet:
Taking Human immunoglobulin with Taftrio Tablet may increase the risk of kidney problems.

How to manage the interaction:
Although taking Human immunoglobulin with Taftrio Tablet can result in an interaction, it can be taken if prescribed by a doctor. However, if you experience symptoms such as nausea, vomiting, loss of hunger, increased or decreased urine, swelling in hands or legs, shortness of breath, muscle pain, tiredness, weakness, confusion, or slow or rapid heart rate, consult a doctor. Do not discontinue any medication without consulting a doctor.
Tenofovir alafenamide + EmtricitabineIbandronic acid
Severe
How does the drug interact with Taftrio Tablet:
Taking Ibandronic acid with Taftrio Tablet may increase the risk of kidney problems.

How to manage the interaction:
Although taking Ibandronic acid with Taftrio Tablet can result in an interaction, it can be taken if prescribed by a doctor. However, if you experience symptoms such as nausea, vomiting, loss of hunger, increased or decreased urine, swelling in hands or legs, shortness of breath, muscle pain, tiredness, weakness, confusion, or slow or rapid heart rate, consult a doctor. Do not discontinue any medication without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[ANTIVIRALS]

FAQs

Taftrio Tablet is used to treat HIV Infection.

Taftrio Tablet works by inhibiting the HIV reverse transcriptase enzymes necessary for the virus's DNA reproduction.

No, completing the treatment course prescribed by the doctor is always recommended. Sudden discontinuation of the medicine can lead to serious side effects. Your doctor will decide whether to stop the medication or not.

Taftrio Tablet doesnot cure HIV infection. However, it helps to control the disease and prevent opportunistic infections. Taftrio Tablet is used in combination with other anti-retroviral medicines.

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Author Details

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Country of origin

India

Manufacturer/Marketer address

7-2-A2, Hetero Corporate, Industrial Estates, Sanath Nagar, Hyderabad - 500 018. Telangana, India
Other Info - TAF0029
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