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  3. Tacromus 0.25 mg Capsule 10's

Tacromus 0.25 mg Capsule 10's, Pack of 10 CAPSULES
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Written By Veda Maddala , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy

Tacromus 0.25 mg Capsule is used to prevent rejection of a transplanted organ, such as a liver, kidney, or heart. It contains Tacrolimus, which works by suppressing the activity of T and B lymphocytes (cells in the immune system) that usually attack foreign invaders and defend the body against foreign cells and infection. Thus, it prevents organ rejection in transplanted patients and helps the body to accept the new organ.

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Composition :

TACROLIMUS-0.25MG

Manufacturer/Marketer :

Zydus Healthcare Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Tacromus 0.25 mg Capsule

Tacromus 0.25 mg Capsule is used to prevent rejection of a transplanted organ, such as a liver, kidney, or heart. Organ rejection occurs when a patient’s immune system recognises the donor organ as foreign and tries to eliminate it.

Tacromus 0.25 mg Capsule contains Tacrolimus, which works by suppressing the activity of T and B lymphocytes (cells in the immune system) that usually attack foreign invaders and defend the body against foreign cells and infection. Thus, it prevents organ rejection in transplanted patients and helps the body to accept the new organ.

Take Tacromus 0.25 mg Capsule as prescribed. You are advised to use Tacromus 0.25 mg Capsule for as long as your doctor has recommended it for you based on your medical condition. Some people may experience nausea, diarrhoea, headache, kidney problems, infection, fever, constipation or high blood pressure. Most of these side effects of Tacromus 0.25 mg Capsule do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Tacrolimus or any other medicines, please tell your doctor. If you are pregnant or a breastfeeding mother, it is advised to consult a doctor before using Tacromus 0.25 mg Capsule . Avoid alcohol consumption with Tacromus 0.25 mg Capsule . Drive only if you are alert, as Tacromus 0.25 mg Capsule may cause some people vision problems or nervous disturbances. If you are about to get vaccinated, inform your doctor before taking Tacromus 0.25 mg Capsule . Tacromus 0.25 mg Capsule may increase the risk of infections or skin cancer as it lowers the body’s immune defence system.

Uses of Tacromus 0.25 mg Capsule

Tacromus 0.25 mg Capsule is used to treat various medical conditions. The detailed uses are as follows:

  • Prevention of Organ Transplant Rejection: Tacromus 0.25 mg Capsule is used to stop the body from rejecting a transplanted kidney, liver, heart, or lung. It works by lowering the activity of certain immune cells that could attack the new organ. It is usually given along with other anti-rejection medicines.
  • Other Off-Label Uses: In some cases, Tacromus 0.25 mg Capsule may be used for graft-versus-host disease (after bone marrow or stem cell transplant), autoimmune liver diseases (autoimmune hepatitis, lupus nephritis), autoimmune eye conditions (uveitis, scleritis), and other immune-related disorders such as rheumatoid arthritis, Crohn’s disease, or myasthenia gravis, particularly when standard treatments are not effective.

Directions for Use

  • Take Tacromus 0.25 mg Capsule at least 1 hour before or 2 to 3 hours after a meal or as advised by your doctor.
  • Strictly follow your doctor's recommendation regarding the dosage and duration.
  • Swallow it as a whole with water.
  • Do not crush, break or chew it.

Medicinal Benefits

  • Tacromus 0.25 mg Capsule belongs to the class of medicines called immunosuppressants, which reduce the activity of the body's immune system, and it contains Tacrolimus as the active ingredient.
  • It works by lowering the activity of certain white blood cells (T-lymphocytes) that trigger immune reactions, helping to prevent the body from attacking transplanted organs and reducing harmful immune responses.
  • It is used to prevent rejection of kidney, liver, heart, or lung transplants, usually along with other anti-rejection medicines.
  • It may also be used for graft-versus-host disease, autoimmune liver conditions, autoimmune eye inflammation, and certain severe autoimmune diseases (such as rheumatoid arthritis, Crohn's disease, or myasthenia gravis) when other treatments are not effective.
  • It provides several benefits, including protecting transplanted organs from rejection, improving long-term transplant survival, reducing the need for high-dose steroids, managing severe immune reactions in certain diseases, and improving quality of life for transplant patients.

How Tacromus 0.25 mg Capsule Works

Tacromus 0.25 mg Capsule contains Tacrolimus, which works by suppressing the activity of T and B lymphocytes (cells in the immune system) that usually attack foreign invaders and defend the body against foreign cells and infection. Thus, it prevents organ rejection in transplanted patients and helps the body to accept the new organ.

Storage

• Store in a cool and dry place away from sunlight.• Keep Tacromus 0.25 mg Capsule out of the sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

What if I have taken an overdose of Tacromus 0.25 mg Capsule

Do not take more than the prescribed dose. Using more medication will not improve your symptoms; rather, it may cause poisoning or serious side effects. If you suspect that you may have overdosed of Tacromus 0.25 mg Capsule or if you experience any adverse events, please go to the emergency department of the closest hospital.

Drug Warnings

  • Inform your doctor if you are allergic to Tacrolimus or any other medicines before starting Tacromus 0.25 mg Capsule .
  • If you are pregnant or breastfeeding, consult your doctor before using Tacromus 0.25 mg Capsule to ensure it is safe for you and your baby.
  • Avoid alcohol consumption while taking Tacromus 0.25 mg Capsule , as it may increase side effects.
  • Drive or operate machinery only if you feel alert, since Tacromus 0.25 mg Capsule may occasionally cause vision problems, dizziness, or nervous system disturbances.
  • Inform your doctor before receiving any vaccines, as Tacromus 0.25 mg Capsule suppresses the immune system and may reduce the effectiveness of certain vaccines.
  • Tacromus 0.25 mg Capsule can increase the risk of infections and skin cancer due to lowered immune defence; use protective clothing and sunscreen while outdoors.
  • When preparing the oral suspension, use glass or metal containers only, as the granules can stick to plastic (PVC) and result in an incomplete dose.
  • Avoid inhaling the granules or letting them, or the prepared suspension, come into contact with your skin or eyes. If accidental contact occurs, wash the area thoroughly with soap and water or rinse eyes with plain water.

Diet & Lifestyle Advise

  • Eat a balanced diet rich in fruits, vegetables, whole grains, lean proteins, and healthy fats to support immune system balance and overall recovery after transplant.
  • Limit salt intake to help manage blood pressure, which can be affected by Tacrolimus and other transplant medications.
  • Avoid grapefruit and grapefruit juice, as they can increase Tacrolimus levels in the blood and raise the risk of side effects.
  • Stay hydrated by drinking enough water daily to support kidney function and prevent dehydration.
  • Limit alcohol consumption or avoid it entirely, as it can stress the liver and interfere with medication effectiveness.
  • Avoid undercooked or raw meat, seafood, and unpasteurised dairy products to reduce the risk of infections that can compromise your immune system.
  • Practice good hand hygiene and food safety to minimise exposure to harmful bacteria or viruses.
  • Maintain a healthy weight through a balanced diet and light physical activity, as recommended by your doctor.
  • Avoid herbal supplements or over-the-counter medicines without medical advice, as they can interact with Tacrolimus and other immunosuppressants.
  • Manage stress and get adequate rest, as this supports immune health and overall well-being during long-term transplant recovery.

Habit Forming

No

Therapeutic Class

IMMUNOSUPPRESSANTS

Tacromus 0.25 mg Capsule Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Unsafe

Avoid alcohol consumption with Tacromus 0.25 mg Capsule as it may increase the risk of adverse effects. Please consult a doctor before consuming alcohol with Tacromus 0.25 mg Capsule .

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Pregnancy

Caution

Using Tacrolimus during pregnancy may cause kidney dysfunction or neonatal hyperkalemia (high potassium levels in the blood). Therefore, please consult a doctor if you are pregnant before taking Tacromus 0.25 mg Capsule and if you are a woman of childbearing age, use effective contraceptive methods while using Tacromus 0.25 mg Capsule .

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Breast Feeding

Consult your doctor

Tacromus 0.25 mg Capsule may be excreted in breast milk. Therefore, please inform your doctor if you are a breastfeeding mother before taking Tacromus 0.25 mg Capsule . You should avoid taking Tacromus 0.25 mg Capsule during breastfeeding or avoid breastfeeding while on treatment with Tacromus 0.25 mg Capsule .

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Driving

Caution

Tacromus 0.25 mg Capsule may cause vision problems or nervous disturbances in a few people. Therefore, avoid driving if you experience any of these symptoms after taking Tacromus 0.25 mg Capsule .

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Liver

Consult your doctor

Please consult a doctor if you have liver diseases/conditions before taking Tacromus 0.25 mg Capsule .

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Kidney

Consult your doctor

Please consult a doctor if you have Kidney diseases/conditions before taking Tacromus 0.25 mg Capsule .

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Children

Safe if prescribed

Tacromus 0.25 mg Capsule should be used in children in doses as advised by a doctor only.

Have a query?

FAQs

Tacromus 0.25 mg Capsule is used to prevent rejection of a transplanted organ, such as a liver, kidney, or heart.

Tacromus 0.25 mg Capsule contains Tacrolimus, an immunosuppressant that works by inhibiting the activity of T and B lymphocytes (cells in the immune system) that usually attack foreign invaders and defend the body against foreign cells and infection. As a result, it helps the body accept the new organ and prevents organ rejection in patients who have had organ transplants.

Tacromus 0.25 mg Capsule may increase the risk of infections as it may weaken the immune system. Therefore, consult a doctor immediately if you have any signs of infection, such as a sore throat or fever.

Tacromus 0.25 mg Capsule may increase the risk of skin cancer. Therefore, avoid or limit exposure to the sun for extended periods or artificial light such as tanning beds. Wear protective clothing and use sunscreen before going out in the sun.

If you are about to receive any vaccinations, especially live vaccines such as measles, mumps, rubella (MMR), oral polio, varicella, yellow fever, intranasal influenza, BCG and TY21a typhoid vaccines, inform your doctor that you are taking Tacromus 0.25 mg Capsule because it may reduce the effectiveness of the vaccine and increase your risk of contracting the infection that the vaccine is meant to protect against.

Using Tacromus 0.25 mg Capsule with Sirolimus is not recommended in patients who have had heart or liver transplants. It is unknown if kidney transplant recipients can use it safely. Hence, please seek medical advice before combining Tacromus 0.25 mg Capsule with other medications.

Tacromus 0.25 mg Capsule may cause tremors, trembling and shaking of hands. Consult the doctor if this becomes bothersome.

Tacromus 0.25 mg Capsule is usually taken on an empty stomach or 2 to 3 hours after a meal. Wait at least 1 hour until the next meal.

Tacromus 0.25 mg Capsule is a macrolide antibiotic with immunosuppressant properties.

Tacromus 0.25 mg Capsule should not be taken by people who are allergic to any of its components, allergic to sirolimus or any macrolide-antibiotic, during breastfeeding, and receiving live vaccines.

Let the doctor know if you have long QT syndrome, low or high levels of potassium, low levels of calcium or magnesium, an irregular heartbeat, high blood pressure, high cholesterol levels, cystic fibrosis (an inborn disease), heart, kidney, or liver disease. Inform the doctor if you have a weak immune system or if you are due to undergo any vaccination.

Tacromus 0.25 mg Capsule decreases the activity of your immune system, increasing the risk of serious infection and cancer (lymphoma cancer). Consult the doctor if you experience symptoms of infection (sore throat, extreme tiredness, cough, flu-like symptoms, fever,) or cancer (weight loss, swollen lymph nodes in the neck, armpits, or groin, fever, excessive tiredness or weakness, night sweats, cough, chest pain, trouble breathing, or pain, swelling, or fullness in the stomach area).

No, Tacromus 0.25 mg Capsule does not have an abuse potential as it is not a controlled substance.

Side effects of Tacromus 0.25 mg Capsule include nausea, diarrhoea, headache, kidney problems, infection, fever, constipation or high blood pressure. If the side effects persist or worsen, please consult your doctor.

Country of origin

India

Manufacturer/Marketer address

D' Block, 3Rd Floor, Gillander House, Netaji Subhas Road, Kolkata - 700001 (Wb)
Other Info - TAC0228

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Author Details

Veda MaddalaDoctor badge

Written By

Veda Maddala

M Pharmacy

Bayyarapu Mahesh KumarDoctor badge

Reviewed By

Bayyarapu Mahesh Kumar

M Pharmacy

Last Updated

Jul 31, 2025 | 12:12 PM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Reference

  1. https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/050709s031lbl.pdf
  2. https://www.medsafe.govt.nz/consumers/cmi/t/tacrolimussandozcap.pdf
  3. https://www.astellas.com/us/system/files/prografwpi_3.pdf
  4. https://www.medicines.org.uk/emc/product/461/smpc
  5. https://www.accessdata.fda.gov/drugsatfda_docs/label/2018/210115s000,050708s047,050709s040lbl.pdf
  6. https://www.drugs.com/cdi/tacrolimus-granules-for-suspension.html
  7. https://www.astellas.com/us/system/files/prografinstructionstouse_2.pdf

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