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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Tablura 80 mg Tablet is used to treat schizophrenia and bipolar disorder. It contains Lurasidone which works by blocking neurotransmitters and helps regulate mood, thoughts and behaviour. In some cases, this medicine may cause side effects such as nausea, vomiting, sleepiness, weight gain, indigestion, dry mouth, and restlessness. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Whats That

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Synonym :

LURASIDONE HYDROCHLORIDE

Composition :

LURASIDONE-80MG

Manufacturer/Marketer :

Cipla Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Tablura 80 mg Tablet

Tablura 80 mg Tablet used in the treatment of schizophrenia (affects a person's ability to feel, think and behave clearly) and bipolar depression (mood swings). Schizophrenia is a mental condition in which the person may feel, hear or see things that are not there, believe things that are not true, or feel unusually suspicious or confused. Bipolar disorder is characterized by manic episodes in which a person experiences extreme mood swings (variance in thinking) and frequent mood and behaviour changes. 

Tablura 80 mg Tablet contains ‘lurasidone’, which is an antipsychotic drug. It acts by blocking a hormone (dopamine) present in the brain responsible for developing symptoms of schizophrenia and bipolar disorder. Tablura 80 mg Tablet also blocks other neurotransmitters in the brain, such as serotonin. By blocking both, Tablura 80 mg Tablet helps to control the brain's activity and decrease the symptoms of schizophrenia and bipolar disease.

Take Tablura 80 mg Tablet as prescribed by your doctor. You are advised to take Tablura 80 mg Tablet for as long as your doctor has prescribed it for you, depending on your medical conditions. You may experience nausea, vomiting, sleepiness, weight gain, indigestion, dryness in the mouth, akathisia (inability to stay still), stomach discomfort, anxiety, upper abdominal pain, restlessness, agitation (nervous excitement), insomnia (difficulty in sleeping) and increased saliva production. Most of these side effects of Tablura 80 mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Tablura 80 mg Tablet should not be taken in conditions like if you are allergic to lurasidone or any other ingredients present in it. Before taking Tablura 80 mg Tablet , inform your doctor if you have problems associated with the liver, kidney or heart and low blood pressure. It is not recommended for use in children under 13 years of age. Before taking Tablura 80 mg Tablet inform your doctor if you are older than 65 years of age as it causes more side effects. Tell your doctor if you are pregnant or breastfeeding. Tablura 80 mg Tablet causes drowsiness and dizziness. Do not drive unless you are alert.

Uses of Tablura 80 mg Tablet

Treatment of Schizophrenia, Bipolar disorder

Directions for Use

• Tablura 80 mg Tablet can be taken with or without food as advised by a doctor.• It is advised to take Tablura 80 mg Tablet exactly as prescribed by your doctor, following the recommended dosage and duration for your specific medical condition to achieve optimal results• Swallow Tablura 80 mg Tablet as a whole with a glass of water.• Do not crush, chew, or break it.

Medicinal Benefits

Tablura 80 mg Tablet is used to treat certain mood /mental diseases like schizophrenia and depression related to bipolar disorder. Tablura 80 mg Tablet  helps you to feel less nervous, think more clearly and take part in daily life. It may also help to reduce hallucinations (seeing/hearing things that are not there). It alters brain function and improves mood, thinking ability, and social behaviour. It reduces the development of symptoms in patients with schizophrenia, bipolar disorder or other mood disorders. 

How Tablura 80 mg Tablet Works

Tablura 80 mg Tablet contains lurasidone, which is an antipsychotic drug. It acts by blocking a hormone (dopamine) present in the brain responsible for developing symptoms of schizophrenia and bipolar disorder. Tablura 80 mg Tablet also blocks other neurotransmitters in the brain, such as serotonin. By blocking both, Tablura 80 mg Tablet helps to control the brain's activity and decrease the symptoms of schizophrenia and bipolar disease.

Storage

Keep this medicine out of the sight and reach of children.
Side effects of Tablura 80 mg Tablet
  • Avoid driving or operating machinery or activities that require high focus until you know how the medication affects you.
  • Maintain a fixed sleeping schedule, create a relaxing bedtime routine and ensure your sleeping space is comfortable to maximize your sleep quality.
  • Limit alcohol and caffeine as these may worsen drowsiness and disturb sleep patterns.
  • Drink plenty of water as it helps with alertness and keeps you hydrated and for overall well-being.
  • Moderate physical activity can improve energy levels, but avoid intense workouts right before bedtime.
  • Regularly brush your tongue and teeth to prevent Excessive Saliva Production.
  • Avoid eating foods high in sugar or acid since these foods might increase saliva production, which increases the Excessive Saliva Production.
  • Keep your head up straight and maintain proper posture to prevent saliva from collecting in your mouth.
Managing back pain as a side effect of medication requires a combination of self-care techniques, lifestyle modifications, and medical interventions. Here are the steps:
  • Talk to your doctor about your back pain and potential medication substitutes or dose changes.
  • Try yoga or Pilates and other mild stretching exercises to increase flexibility and strengthen your back muscles.
  • To lessen the tension on your back, sit and stand upright and maintain proper posture.
  • To alleviate discomfort and minimize inflammation, apply heat or cold packs to the afflicted area.
  • Under your doctor's supervision, think about taking over-the-counter painkillers like acetaminophen or ibuprofen.
  • Make ergonomic adjustments to your workspace and daily activities to reduce strain on your back.
  • To handle tension that could make back pain worse, try stress-reduction methods like deep breathing or meditation.
  • Use pillows and a supportive mattress to keep your spine in the right posture as you sleep.
  • Back discomfort can worsen by bending, twisting, and heavy lifting.
  • Speak with a physical therapist to create a customized training regimen to increase back strength and flexibility.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.

What if I have taken an overdose of Tablura 80 mg Tablet

Take Tablura 80 mg Tablet only as prescribed by the doctor. Do not exceed the recommended dose, as it might cause an overdose. If you suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

It is advisable to you not take Tablura 80 mg Tablet if you are allergic to lurasidone or any ingredients present in it. Before taking Tablura 80 mg Tablet , inform your doctor if you have low blood pressure, stroke, liver problems, seizures, diabetes, dementia (memory loss), alcohol or drug abuse, sleep apnea (a sleep disorder) and urinary retention. Inform your doctor if you have epilepsy/fits, an increase in your weight, history of blood clots before taking Tablura 80 mg Tablet . Tell your doctor immediately if you develop suicidal thoughts, or your depression worsens after taking Tablura 80 mg Tablet . There is a greater chance of death in senior adults who take Tablura 80 mg Tablet for mental problems caused by dementia (thinking and suicidal symptoms). Most of the deaths were related to infection or heart disease. Avoid drinking alcohol while taking Tablura 80 mg Tablet as it may worsen the side effects. Tell your doctor if you are pregnant or breastfeeding. Tablura 80 mg Tablet causes drowsiness and dizziness. Do not drive unless you are alert.

Drug-Drug Interactions

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LurasidoneBoceprevir
Critical

Drug-Drug Interactions

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How does the drug interact with Tablura 80 mg Tablet:
Using Tablura 80 mg Tablet together with Indinavir may result in significantly higher Tablura 80 mg Tablet blood levels. This may increase the possibility of negative effects like Parkinson's disease. (It is a brain disorder that produces uncontrollable movements.)

How to manage the interaction:
While Tablura 80 mg Tablet and Indinavir may interact, they can be used if prescribed by a doctor. Consult a doctor if you have any abnormal muscle activity, fits, high blood sugar, high sugars, high cholesterol, heat intolerance or heat stroke, dizziness, lightheadedness, headache, flushing, fainting, or heart palpitations. Do not discontinue any medications without consulting a doctor.
LurasidoneBoceprevir
Critical
How does the drug interact with Tablura 80 mg Tablet:
Using Tablura 80 mg Tablet together with Boceprevir may result in significantly higher Tablura 80 mg Tablet blood levels. This may increase the possibility of negative effects like Parkinson's disease. (It is a brain disorder that produces uncontrollable movements.)

How to manage the interaction:
While Tablura 80 mg Tablet and Boceprevir may interact,so it is not recommended, they can be used if prescribed by a doctor. Consult a doctor if you have any abnormal muscle activity, fits, high blood sugar, high sugars, high cholesterol, heat intolerance or heat stroke, dizziness, lightheadedness, headache, flushing, fainting, or heart palpitations. Do not discontinue any medications without consulting a doctor. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Tablura 80 mg Tablet:
Coadministration of Tablura 80 mg Tablet with Mifepristone can increase the levels of Tablura 80 mg Tablet which can increase the risk or severity of side effects.

How to manage the interaction:
Taking Tablura 80 mg Tablet with Mifepristone together is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you notice any abnormal muscle movements, seizures(fits), high blood sugar, dizziness, lightheadedness, headache, flushing, fainting, and heart palpitations, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
How does the drug interact with Tablura 80 mg Tablet:
Using Tablura 80 mg Tablet together with phenytoin may significantly decrease the blood levels of Tablura 80 mg Tablet.

How to manage the interaction:
Using Tablura 80 mg Tablet with phenytoin is not recommended, it can be taken if a doctor has prescribed it. Consult a doctor, if you experience any unusual symptoms. Do not discontinue any medications without consulting a doctor.
LurasidoneFosphenytoin
Critical
How does the drug interact with Tablura 80 mg Tablet:
Tablura 80 mg Tablet co-administration with Fosphenytoin may result in significantly lower blood levels of Tablura 80 mg Tablet, making the medication less effective or ineffective in treating your illness.

How to manage the interaction:
Although there is an interaction between Tablura 80 mg Tablet and Fosphenytoin, you can take it if your doctor has prescribed it. Consult a doctor if you experience any unusual symptoms. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Tablura 80 mg Tablet:
Using Tablura 80 mg Tablet together with Ceritinib may result in significantly increase the blood levels of Tablura 80 mg Tablet.

How to manage the interaction:
Tablura 80 mg Tablet and Ceritinib together are not recommended as they can lead to an interaction. They can be used if prescribed by a doctor. However, consult a doctor if you experience low blood pressure, such as dizziness, lightheadedness, headache, flushing, fainting, and heart palpitations. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Tablura 80 mg Tablet:
Using Tablura 80 mg Tablet together with Darunavir may result in significantly higher Tablura 80 mg Tablet blood levels. This may increase the possibility of negative effects like Parkinson's disease. (It is a brain disorder that produces uncontrollable movements.)

How to manage the interaction:
While Tablura 80 mg Tablet and Darunavir may interact, they can be used if prescribed by a doctor. Consult a doctor if you have any abnormal muscle activity, fits, high blood sugar, high sugars, high cholesterol, heat intolerance or heat stroke, dizziness, lightheadedness, headache, flushing, fainting, or heart palpitations. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Tablura 80 mg Tablet:
Using Tablura 80 mg Tablet together with ketoconazole may increase the risk of side effects like Parkinson's disease(It is a brain disorder that produces uncontrollable movements).

How to manage the interaction:
While Tablura 80 mg Tablet and ketoconazole is not recommended as it may lead to an interaction, they can be used if prescribed by a doctor. However, consult a doctor if you have any abnormal muscle activity, fits, heat intolerance or heat stroke, dizziness, lightheadedness, headache, flushing, fainting, or heart palpitations. Do not discontinue any medications without consulting a doctor.
LurasidoneSaquinavir
Critical
How does the drug interact with Tablura 80 mg Tablet:
Using Tablura 80 mg Tablet together with Saquinavir may result in significantly higher Tablura 80 mg Tablet blood levels. This may increase the possibility of side effects like Parkinson's disease. (It is a brain disorder that produces uncontrollable movements.)

How to manage the interaction:
While Tablura 80 mg Tablet and Saquinavir may interact, it is not recommended that they be used unless prescribed by a doctor. Consult a doctor if you have any abnormal muscle activity, fits, high blood sugar, high sugars, high cholesterol, heat intolerance or heat stroke, dizziness, lightheadedness, headache, flushing, fainting, or heart palpitations. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Tablura 80 mg Tablet:
Taking Tablura 80 mg Tablet together with posaconazole may result in significantly higher Tablura 80 mg Tablet blood levels.

How to manage the interaction:
Although there is an interaction between Tablura 80 mg Tablet and posaconazole, they can be used if prescribed by a doctor. However, consult a doctor if you have any abnormal muscle activity, dizziness, lightheadedness, headache, flushing, or fainting. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Do not take grapefruit or grapefruit juice while using Tablura 80 mg Tablet as it may alter the effects of the medicine.
  • Avoid intense exercise as it is harder for the body to cool down when it gets very hot. So, drink plenty of fluids and avoid going out in hot weather.
  • Do not take alcohol as it increases drowsiness and also worsens the disease condition. 
  • Eat healthily and keep a check on your weight regularly.

Habit Forming

No

Therapeutic Class

ANTIPSYCHOTICS
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Alcohol

Unsafe

Avoid consuming alcohol while on treatment with Tablura 80 mg Tablet as it may increase the risk of side effects.

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Pregnancy

Caution

Tablura 80 mg Tablet is not recommended for use in pregnancy. Hence, if you are pregnant, inform your doctor before taking Tablura 80 mg Tablet . Your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

It is not known if Tablura 80 mg Tablet passes into the breastmilk. If you are breastfeeding, consult your doctor before taking Tablura 80 mg Tablet , your doctor will prescribe this medicine if the benefits outweigh the risks.

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Driving

Caution

Tablura 80 mg Tablet may cause dizziness. So, it is not recommended to drive or operate heavy machinery after taking Tablura 80 mg Tablet .

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Liver

Caution

Tablura 80 mg Tablet should be used with caution in patients with liver disease. If you have liver disease, inform your doctor before taking Tablura 80 mg Tablet . Your doctor may adjust the dose based on your condition.

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Kidney

Caution

Tablura 80 mg Tablet should be used with caution in patients with kidney disease. If you have kidney disease, inform your doctor before taking Tablura 80 mg Tablet . Your doctor may adjust the dose based on your condition.

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Children

Unsafe

Tablura 80 mg Tablet is not recommended for use in children under 13 years.

Have a query?

FAQs

Tablura 80 mg Tablet is used in the treatment of schizophrenia (affects a person's ability to feel, think and behave clearly) and bipolar depression (mood swings). It helps you to feel less nervous, think more clearly and take part in daily life.

Tablura 80 mg Tablet may cause an increase in blood glucose (sugar) levels. So, regular monitoring of blood sugar levels is advised while taking Tablura 80 mg Tablet . Diabetes patients should consult a doctor before taking Tablura 80 mg Tablet .

Weight gain is a common side effect of Tablura 80 mg Tablet , although not everyone is affected. If you experience weight gain on taking Tablura 80 mg Tablet , inform your doctor. Eating a healthy diet and frequent exercise can help you maintain your weight.

Alcohol should be avoided while taking Tablura 80 mg Tablet since taking both together may lead to severe side effects. You should not drink grapefruit juice while on Tablura 80 mg Tablet as it affects the way it works.

Tablura 80 mg Tablet may raise the risk of death in older persons who suffer from memory loss, perplexity, or have lost touch with reality. It is critical to understand that Tablura 80 mg Tablet may cause suicidal behaviour or thoughts in certain children, adolescents, and young adults during the first few months of treatment and when the dose is adjusted.

Dry mouth could be a side-effect of Tablura 80 mg Tablet . Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly and chewing sugar-free gum/candy might help in stimulating saliva and thereby prevents drying of the mouth.

Tablura 80 mg Tablet is an antipsychotic drug that works by blocking a hormone (dopamine) present in the brain responsible for developing symptoms of schizophrenia (a serious mental illness affecting thoughts, feelings, and behaviours) and bipolar disorder (a mental illness that causes mood swings, energy fluctuations, and concentration issues). It also blocks other neurotransmitters in the brain, such as serotonin. By blocking both dopamine and serotonin, Tablura 80 mg Tablet helps to control brain activity and decreasesthe symptoms of schizophrenia and bipolar disorder.

The common side effects of Tablura 80 mg Tablet include nausea, vomiting, weight gain, indigestion, sleepiness, dryness in the mouth, increased saliva production, akathisia (inability to stay still), anxiety, upper abdominal pain, restlessness, agitation (nervous excitement), and insomnia (difficulty in sleeping). Most of these side effects of Tablura 80 mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

No, Tablura 80 mg Tablet should not be used during pregnancy unless prescribed by the doctor. Taking Tablura 80 mg Tablet in the later months of pregnancy may lead to extrapyramidal (uncontrolled body movements or muscle stiffness in the baby) or withdrawal symptoms after birth such as muscle stiffness, weakness, shakiness, sleepiness, breathing problems, agitation, and difficulty feeding. If you are pregnant or planning for pregnancy, please consult your doctor before taking Tablura 80 mg Tablet . The doctor will prescribe Tablura 80 mg Tablet only if the benefits outweigh the risks and will monitor the baby closely after birth.

Close monitoring for the emergence or worsening of suicidal behaviour and thoughts is recommended in patients taking Tablura 80 mg Tablet . Tablura 80 mg Tablet may increase blood sugar levels in diabetic patients, especially in those with schizophrenia. So, you should immediately inform your doctor if you experience symptoms such as increased thirst, frequent urination, fatigue, or increased appetite. It may also lead to weight gain, increase prolactin, cholesterol, and triglyceride levels, and decrease white blood cell count. Hence, regular monitoring of blood sugar levels, blood cell counts, hormone levels (prolactin), and cholesterol levels is advised while taking Tablura 80 mg Tablet . 

Tablura 80 mg Tablet should be taken with food for better absorption of the medicine. It should be swallowed whole with a glass of water; do not chew or crush the tablet.

Tablura 80 mg Tablet may take several weeks or longer before you experience any improvement in your symptoms. Continue to take Tablura 80 mg Tablet even if you feel well, and do not stop taking it without talking to your doctor.

Yes, Tablura 80 mg Tablet can cause dizziness, fainting, and lightheadedness when you stand up too quickly after lying down. This is more likely to happen when you first start taking Tablura 80 mg Tablet or if your dose changes. To help prevent this problem, rise slowly from the bed and allow your feet to rest on the floor for a few minutes before standing up.

Country of origin

India

Manufacturer/Marketer address

Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013
Other Info - TAB0036

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