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  3. Systaflam Gel 25 gm

Systaflam Gel 25 gm, Pack of 1 Gel
Systaflam Gel 25 gm, Pack of 1 Gel
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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy

Systaflam Gel is used to relieve pain and inflammation associated with musculoskeletal disorders, strain, sprain, arthritis, and low back pain. It blocks the release of certain chemical messengers in the brain that are responsible for causing pain and symptoms of inflammation, redness, and swelling. Also, it works on the brain and spinal cord centres to relieve muscle hardness or spasms and improve the pain and movement of muscles. It may cause side effects such as a burning sensation, irritation, itching and redness at the application site. Do not apply it to wounded or damaged skin.

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Composition :

DICLOFENAC-1%W/W + MENTHOL-2%W/W + MEPHENESIN-5%W/W + METHYL SALICYLATE-5%W/W + TURPENTINE OIL-3%W/W

Manufacturer/Marketer :

Systopic Laboratories Pvt Ltd

Consume Type :

TOPICAL

Return Policy :

Not Returnable

Expires on or after :

About Systaflam Gel

Systaflam Gel is a combination medicine used to relieve pain and inflammation associated with musculoskeletal disorders, strain, sprain, arthritis, and low back pain. Musculoskeletal pain could occur due to arthritis, osteoporosis, fractures, dislocations, problems with the bone structure, or injury to the bones, joints, tendons, muscles, and ligaments. Osteoarthritis is a joint disease in which the two ends of the joints come together due to the breakdown of a protective covering called cartilage.

Systaflam Gel combines five medicines: Diclofenac, Mephenesin, Menthol, Turpentine oil and Methyl salicylate. Diclofenac is a non-steroidal anti-inflammatory drug (NSAID) that blocks the release of certain chemical messengers in the brain, which are responsible for causing pain and symptoms of inflammation, redness, and swelling. Mephenesin is a muscle relaxant (that relaxes the muscle and treats muscle pain). It works on the brain and spinal cord centres to relieve muscle hardness or spasms and improve the pain and movement of muscles. Methyl salicylate and Menthol are topical analgesics (applied directly to alleviate pain). They work initially by cooling the skin, followed by warming it up. This action helps improve blood circulation and relieve pain. Turpentine Oil is a lubricant.

Systaflam Gel is for external use only. Avoid getting the Systaflam Gel in contact with your eyes, nose or mouth. Do not apply it to wounded or damaged skin. In case of accidental contact, immediately rinse it with cold water. Like all medicines, Systaflam Gel can cause side effects, although not everybody gets them. You might experience side effects such as a burning sensation, irritation, itching and redness at the application site. Most of these side effects of Systaflam Gel do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Do not use this medicine without consulting your doctor. Even though drugs used topically (directly applied) on the skin are not normally affected by any other medication, you should inform your doctor if you are taking any other medicine. Also, inform your doctor if you have had an allergic reaction to diclofenac or any other drugs in the past, any cut or infected skin and ever had signs of any lung, liver, kidney-related diseases/disorders, muscle weakness (myasthenia gravis), sleeping disorder or difficulty in sleeping (sleep apnoea). Please tell your doctor if you are pregnant or breastfeeding to avoid unnecessary risks.

Uses of Systaflam Gel

Systaflam Gel is used in the treatment of pain and inflammation associated with musculoskeletal and joint disorders. The detailed uses of Systaflam Gel are as follows:<br/> • Pain Relief: Systaflam Gel is commonly used to relieve localised pain such as muscle aches, joint pain, and back pain.<br/> • Anti-inflammatory: Systaflam Gel helps reduce inflammation in conditions like arthritis or sports injuries, easing discomfort and swelling.<br/> • Muscle Strains and Sprains: Systaflam Gel can be applied to affected areas to help accelerate recovery from muscle strains or sprains by providing symptomatic relief.<br/> • Post-operative Pain: After certain surgeries, Systaflam Gel may be used to manage pain at the surgical site, allowing for easier mobility.<br/> • Chronic Conditions: Individuals suffering from chronic pain conditions such as osteoarthritis may use it regularly to help manage symptoms and improve their quality of life.<br/>

Directions for Use

  • Follow your doctor's instructions on the dosage and timing of this medication.
  • Clean and dry the affected area and apply the gel by gently spreading it over the affected area.
  • Wash your hands after applying it, unless your hands are the affected area.
  • Avoid contact of the Systaflam Gel with the nose or eyes. In case of accidental contact with these areas, rinse with water thoroughly.

Medicinal Benefits

Systaflam Gel combines five medicines: Diclofenac, Mephenesin, Menthol, Turpentine oil, and Methyl salicylate. Here, diclofenac works by blocking the release of certain chemical messengers in the brain that are responsible for causing pain and signs of inflammation such as redness and swelling. Mephenesin is a muscle relaxant (that relaxes the muscle and treats muscle pain). It works on the brain and spinal cord centres to relieve muscle hardness or spasms and improve the pain and movement of muscles. On the other hand, methyl salicylate and menthol work by causing the skin to feel cool and warm. This action helps improve blood circulation and thus provides relief from pain. Turpentine Oil is a lubricant.

How Systaflam Gel Works

Systaflam Gel combines five medicines: Diclofenac, Mephenesin, Menthol, Turpentine oil and Methyl salicylate. Diclofenac is a non-steroidal anti-inflammatory drug (NSAID) that blocks the release of certain chemical messengers in the brain, which are responsible for causing pain and symptoms of inflammation, redness, and swelling. Mephenesin is a muscle relaxant (that relaxes the muscle and treats muscle pain). It works on the brain and spinal cord centres to relieve muscle hardness or spasms and improve the pain and movement of muscles. Methyl salicylate and Menthol are topical analgesics (applied directly to alleviate pain). They work initially by cooling the skin, followed by warming it up. This action helps improve blood circulation and relieve pain. Turpentine Oil is a lubricant.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

What if I have taken an overdose of Systaflam Gel

Do not apply Systaflam Gel in large amounts or use it for a long time than recommended, as it does not give quick or better results but increases the risk of side effects.

Drug Warnings

Consumption of alcohol should be avoided during the treatment with Systaflam Gel as it may lead to an increased risk of liver damage. Patients with stomach ulcers, gastric bleeding, severe heart failure, high blood pressure and liver or kidney disease should not take Systaflam Gel. Besides this, it should be avoided during the last trimester of pregnancy unless the doctor has prescribed it. If you have a severe allergy to painkillers and have conditions like asthma, rhinitis, angioedema (swelling under the skin) or skin rashes, immediately stop taking Systaflam Gel.

Drug-Drug Interactions

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No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

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Drug-Food Interactions

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Diet & Lifestyle Advise

  • Include more glucosamine, chondroitin sulfate, Vitamin D, and calcium-enriched supplements. Besides this, turmeric and fish oils can help reduce inflammation in the tissue.
  • Please do not go for heavy exercise, as it may increase your joint pain in arthritis. Instead, you can do stretching and low-impact aerobic exercises like walking on a treadmill, biking, and swimming. You can also strengthen your muscle strength by lifting light weights.
  • In chronic conditions of arthritis or joint pain, fish like salmon, trout, tuna, and sardines are also used. These fish are enriched with omega-3 fatty acids and contain a minimum of chemicals called cytokines, which ramp up inflammation.
  • Your sitting posture is important, especially when you have pain and inflammation. Try to sit as little as possible and only for a short time (10-15 min). Use back support like a rolled-up towel to minimise pain at the back of your curve. Keep your knees and hips at a right angle. Besides this, you can use a footrest if required.

Habit Forming

No

Therapeutic Class

ANALGESICS

Systaflam Gel Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Consult your doctor

It is unknown whether it is safe to consume alcohol with Systaflam Gel. However, as a precautionary measure, it is advisable not to take or limit alcohol.

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Pregnancy

Consult your doctor

Systaflam Gel is not recommended during pregnancy unless your doctor considers it essential. Please consult the doctor. Your doctor will weigh the benefits and potential risks before prescribing them.

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Breast Feeding

Consult your doctor

Systaflam Gel should not be used in nursing mothers unless necessary. So, inform your doctor if you are a nursing mother. Your doctor will weigh the benefits and potential risks before prescribing Systaflam Gel.

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Driving

Safe if prescribed

Systaflam Gel does not impact your ability to drive or operate machinery.

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Liver

Consult your doctor

Limited information was available about using Systaflam Gel in patients with liver disease. If you have concerns about utilising Systaflam Gel in patients with liver disease, please visit your doctor. Only if the benefits outweigh the risks will your doctor prescribe.

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Kidney

Consult your doctor

Limited information was available about using Systaflam Gel in patients with kidney disease. If you have concerns about utilising Systaflam Gel in patients with kidney disease, please visit your doctor. Your doctor will prescribe only if the benefits outweigh the risks.

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Children

Unsafe

Systaflam Gel is not recommended for children as safety and effectiveness have not been established.

Have a query?

FAQs

Systaflam Gel is used to relieve pain and inflammation associated with musculoskeletal disorders, strain, sprain, arthritis, and low back pain.

Systaflam Gel combines five medicines: Diclofenac, Mephenesin, Menthol, Turpentine oil and Methyl salicylate. Diclofenac is a non-steroidal anti-inflammatory drug (NSAID) that blocks the release of certain chemical messengers in the brain, which are responsible for causing pain and symptoms of inflammation, redness, and swelling. Mephenesin is a muscle relaxant (that relaxes the muscle and treats muscle pain). It works on the brain and spinal cord centres to relieve muscle hardness or spasms and improve the pain and movement of muscles. Methyl salicylate and Menthol are topical analgesics (applied directly to alleviate pain). They work initially by cooling the skin, followed by warming it up. This action helps improve blood circulation and relieve pain. Turpentine Oil is a lubricant.

Avoid concomitant use of Systaflam Gel with other topical products such as cosmetics, sunscreens, lotions, moisturizers, insect-repellent creams, and other gels.

Please do not take any NSAID/painkiller medicines along with Systaflam Gel as it could increase the risk of ulceration, perforation, and bleeding in the stomach and intestine. Inform your doctor before using Systaflam Gel if you are taking any NSAIDs orally.

No, the use of Systaflam Gel is contraindicated on the broken or cut wound skin. It should be only applied topically on the uppermost skin surfaces (epidermis). It should not be applied in the nostrils, vagina or anus.

No, it is not advised to use Systaflam Gel in patients with severe heart failure.

Avoid or limit exposure to natural or artificial sunlight as Systaflam Gel may cause ultraviolet light-induced skin tumours.

Country of origin

India

Manufacturer/Marketer address

Systopic Laboratories Pvt. Ltd., 101, Pragati Chambers, Commercial Complex, Ranjit Nagar, New Delhi-110008
Other Info - SYS0005

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Author Details

Santoshini Reddy GDoctor badge

Written By

Santoshini Reddy G

M Pharmacy

Bayyarapu Mahesh KumarDoctor badge

Reviewed By

Bayyarapu Mahesh Kumar

M Pharmacy

Last Updated

Jul 21, 2025 | 2:17 PM IST

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Reference

  1. https://www.webmd.com/drugs/2/drug-174535-1065/diclofenac-methyl-salicylate-menthol-topical/diclofenac-1-topical/details
  2. https://www.sastasundar.com/index.php/product/generic/diclofenac-menthol-mephenesin-methyl-salicylate/1419
  3. https://www.webmd.com/drugs/2/drug-1293/mephenesin-bulk/details/list-interaction-medication
  4. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=fa136af1-d3ea-4038-95af-e937555f8f5d&amp;audience=consumer

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