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compositionComposition:ACECLOFENAC-100MG+PARACETAMOL-500MG
prescriptionPrescription Medicine
Synerzen Tablet 10's

Synerzen Tablet is used to reduce pain and inflammation. It helps in relieving pain from conditions like headaches, mild migraine, muscle pain, dental pain, rheumatoid arthritis, ankylosing spondylitis, and osteoarthritis. It contains Aceclofenac and Paracetamol, which work by blocking the chemical messengers responsible for causing pain, inflammation, and fever. In some cases, it may cause side effects like dizziness, nausea, digestion problems (constipation, flatulence, diarrhoea) and skin reactions (like rashes and hives). Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

ACECLOFENAC-100MG+PARACETAMOL-500MG

Manufacturer/Marketer :

Zeno Bio Life Science Pvt Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Synerzen Tablet

Synerzen Tablet is used to reduce pain and inflammation. The pain is an unpleasant sensory and emotional experience associated with actual or potential tissue damage. Inflammation is a localized physical condition in which part of the body becomes reddened, swollen, hot and often painful.

Synerzen Tablet is composed of aceclofenac and paracetamol. Aceclofenac and Paracetamol both work by blocking the chemical messengers responsible for causing pain, inflammation, and fever.

Synerzen Tablet may cause side effects like dizziness, nausea, constipation, flatulence, diarrhoea, rashes and hives. Most of the side effects of Synerzen Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Avoid taking Synerzen Tablet if you are allergic to any of the ingredients present in it. Taking more than the daily prescribed dose of Synerzen Tablet may cause liver damage or allergic reactions like swelling of the mouth, face, throat, difficulty in breathing, skin rash, itching, gastrointestinal bleeding and/or ulcer. 

Uses of Synerzen Tablet

Synerzen Tablet is used in the treatment of Pain, Inflammation, and fever. The detailed uses of Synerzen Tablet are as follows:

  • Pain Relief: Synerzen Tablet is used to relieve pain, by its analgesic effects, which block pain signals and reduce discomfort.
  • Inflammation: Synerzen Tablet helps to reduce inflammation and swelling associated with conditions like arthritis, osteoarthritis, and rheumatoid arthritis.
  • Fever Reduction: Synerzen Tablet is used to bring down elevated body temperature, providing relief from discomfort associated with fever.

Key Benefits

  • Synerzen Tablet helps to reduce pain and inflammation caused by various complications or conditions.
  • It significantly works on providing relief from pain for extended hours.
  • It contains paracetamol, which is less irritant to the stomach than other painkillers. Hence, it is well tolerated by patients who have an allergy to aspirin or a risk of gastrointestinal bleeding or ulcer formation.
  • Besides this, it does not affect bleeding time and also helps in reducing fever due to pain or swelling.
Side effects of Synerzen Tablet
Here are the step-by-step strategies to manage the side effects of "indigestion" caused by medication usage:
  • Take medications with food (if recommended): It can help prevent stomach distress and indigestion.
  • Eat smaller, more frequent meals: Divide daily food intake into smaller, more frequent meals to ease digestion.
  • Avoid trigger foods: Identify and avoid foods that trigger indigestion, such as spicy, fatty, or acidic foods.
  • Stay upright after eating: Sit or stand upright for at least 1-2 hours after eating to prevent stomach acid from flowing into the oesophagus.
  • Avoid carbonated drinks: Avoid drinking carbonated beverages, such as soda or beer, which can worsen indigestion.
  • Manage stress: To alleviate indigestion, engage in stress-reducing activities like deep breathing exercises or meditation.
  • Consult a doctor if needed: If indigestion worsens or persists, consult a healthcare professional to adjust the medication regimen or explore alternative treatments.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.

Directions for Use

  • Synerzen Tablet can be taken with or without food, preferably with a meal.
  • Follow your doctor's instructions on the dosage and timing of this medication.
  • Swallow Synerzen Tablet as a whole with a glass of water.
  • Do not crush, break, or chew it.

How Synerzen Tablet Works

Synerzen Tablet is composed of two medicines: Aceclofenac (pain reducer) and Paracetamol (fever reducer). Synerzen Tablet helps in relieving pain from conditions like headaches, mild migraine, muscle pain, dental pain, rheumatoid arthritis, ankylosing spondylitis, and osteoarthritis. Aceclofenac and Paracetamol both work by blocking the chemical messengers responsible for causing pain, inflammation, and fever.
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Alcohol

Unsafe

You are recommended not to consume alcohol along with Synerzen Tablet as it contains paracetamol which can together damage your liver severely.

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Pregnancy

Consult your doctor

The safety of this medicine for use during pregnancy is not known. Hence, it is not recommended for use in pregnancy unless considered essential by your doctor.

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Breast Feeding

Consult your doctor

Synerzen Tablet should not be used without consultation with your doctor if you are breast-feeding. It is not known if this medicine passes into breast milk. It is not recommended for use during breast-feeding unless considered essential by your doctor.

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Driving

Unsafe

Synerzen Tablet usually causes dizziness, drowsiness and visual disturbances which may affect their ability to drive or operate machinery. Make sure you are not affected before driving or operating machinery.

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Liver

Caution

Synerzen Tablet to be taken with caution, especially if you have a history of liver disease. The dose may have to be adjusted by your doctor.

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Kidney

Caution

Synerzen Tablet to be taken with caution, especially if you have a history of kidney disease. The dose may have to be adjusted by your doctor.

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Children

Unsafe

The safety and efficacy of Synerzen Tablet in children have not been established. Synerzen Tablet is not recommended in children.

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Heart

Unsafe

Synerzen Tablet should be avoided in cardiac patients as it can lead to serious cardiavascular risks

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Geriatrics

Caution

Synerzen Tablet should be used under caution in geriatric patients as it can lead to serious side effects/

What if I have taken an overdose of Synerzen Tablet

Do not take more than the prescribed dose of Synerzen Tablet as it may cause adverse effects. If you suspect you have taken an overdose, please consult a doctor immediately.

Diet & Lifestyle Advise

  • Include more glucosamine, chondroitin sulphate, Vitamin D, and calcium-enriched supplements. Besides this, turmeric and fish oils can help in reducing inflammation in the tissue.
  • Do not go for heavy exercise as it may increase your joint pain and arthritis. Instead, you can do stretching and low-impact aerobic exercises like walking on a treadmill, bike riding, and swimming. You can also strengthen your muscle strength by lifting light weights.
  • In chronic arthritis or joint pain, try to include fish like salmon, trout, tuna, and sardines. These fishes are enriched with omega-3 fatty acids that have a minimum level of chemicals called cytokines, which ramp up inflammation.
  • Your sitting posture is important, especially when you have pain and inflammation conditions. Try to sit as little as possible and only for a short time (10-15 min). Use back support like a rolled-up towel at the back of your curve to minimize pain. Keep your knees and hips at a right angle. Besides this, you can use a footrest if required.

Have a query?

How Soon It Starts Working

  • The time required for Synerzen Tablet to start to work: Synerzen Tablet ideally shows its action within 30 minutes after administration. 
  • The time for which the effects of Synerzen Tablet last: The effect of Synerzen Tablet lasts 8 to 12 hours.

What if you forget to take Synerzen Tablet

If you miss a dose, take it as soon as you remember. If it is almost time for the next dose, skip the missed dose and take the next dose at the scheduled time. Do not take a double dose.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Drug Warnings

  • Do not take Synerzen Tablet if you are allergic to it or its components.
  • Taking more than the daily prescribed dose of Synerzen Tablet may cause liver damage or allergic reactions like swelling of the mouth, face, throat, difficulty in breathing, skin rash or itching.
  • Most of the cases of liver injury are associated with the use of paracetamol. 
  • Gastrointestinal bleeding and ulcer formation are commonly observed with the use of Synerzen Tablet , so the doctor may prescribe you the lowest dose available.
  • Do not take Synerzen Tablet if you have asthma or allergies to painkillers, heart, kidney and liver conditions.
  • Synerzen Tablet should not be taken during pregnancy or by breastfeeding mothers as it may affect the baby.
  • The components of Synerzen Tablet can cause stomach upset. Thus, it is recommended to consume Synerzen Tablet with meals to minimize gastric side effects. If you have a diagnosis of peptic ulcer, Synerzen Tablet is best avoided unless prescribed by your doctor.
  • Although Synerzen Tablet provides symptomatic relief, it is strongly recommended to remain physically active as much as your condition allows.
  • Adopting a healthy lifestyle, coupled with a healthy diet containing high proteins, is the mainstay of the management of arthritic conditions.

Drug-Drug Interactions

verifiedApollotooltip

Drug-Drug Interaction: Synerzen Tablet interact with cholesterol lowering drugs (cholestyramine), charcoal, medicine to stop vomiting (domperidone, metochlopramide), alcohol, anti HIV drug (zidovudine), blood thinner (warfarin), blood pressure lowering medicine, anti cancer or anti arthritis drug (methotrexate) may lead to drug toxicity or affect the working of Synerzen Tablet . So, contact the doctor before taking these medicines.

Drug-Food Interaction: No interaction found.

Drug-Disease Interaction: Patient affected with liver disease, bleeding disorder and alcoholism should not take Synerzen Tablet as it has a risk of causing derangement in liver functions.

Aceclofenac + ParacetamolLeflunomide
Severe
Aceclofenac + ParacetamolMipomersen
Severe

Drug-Drug Interactions

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Aceclofenac + ParacetamolLeflunomide
Severe
How does the drug interact with Synerzen Tablet:
Co-administration of Synerzen Tablet and Leflunomide may increase the risk of liver problems.

How to manage the interaction:
Although there is a possible interaction between Synerzen Tablet and Leflunomide, they can be taken together if prescribed by a doctor. However, if you experience symptoms such as fever, chills, swollen or painful joints, unexpected bleeding or bruises, skin rash, itching, vomiting, abdominal pain, light-colored stool, dark-colored urine, yellowing of the skin or eyes, decreased hunger, consult the doctor. Do not stop using any medications without talking to the doctor.
Aceclofenac + ParacetamolMipomersen
Severe
How does the drug interact with Synerzen Tablet:
Co-administration of Synerzen Tablet with Mipomersen may increase the risk or severity of liver injury.

How to manage the interaction:
There may be a possibility of interaction between Synerzen Tablet and Mipomersen, but it can be taken if prescribed by a doctor. However, if you experience symptoms such as fever, chills, swollen or painful joints, unexpected bleeding or bruises, skin rash, itching, vomiting, abdominal pain, light-colored stool, dark-colored urine, yellowing of the skin or eyes, decreased hunger, consult the doctor. Do not stop using any medications without talking to the doctor.
Aceclofenac + ParacetamolEthanol
Severe
How does the drug interact with Synerzen Tablet:
Co-administration of Synerzen Tablet with Ethanol can increase the risk of liver damage.

How to manage the interaction:
Although taking Synerzen Tablet with Ethanol can lead to an interaction, it can be taken if prescribed by the doctor. However, if you experience symptoms such as fever, chills, swollen or painful joints, unexpected bleeding or bruises, skin rash, itching, vomiting, abdominal pain, light-colored stool, dark-colored urine, yellowing of the skin or eyes, decreased hunger, consult the doctor. Do not stop using any medications without talking to the doctor.
Aceclofenac + ParacetamolLomitapide
Severe
How does the drug interact with Synerzen Tablet:
Co-administration of Lomitapide and Synerzen Tablet may increase the risk of severity of liver injury.

How to manage the interaction:
Although there is a possible interaction between Synerzen Tablet and Lomitapide, you can take these medicines together if prescribed by a doctor. However, if you experience symptoms such as fever, chills, swollen or painful joints, unexpected bleeding or bruises, skin rash, itching, vomiting, abdominal pain, light-colored stool, dark-colored urine, yellowing of the skin or eyes, decreased hunger, consult the doctor. Do not stop using any medications without talking to the doctor.
Aceclofenac + ParacetamolKetoconazole
Severe
How does the drug interact with Synerzen Tablet:
Co-administration of Synerzen Tablet and Ketoconazole may increase the risk of liver injury.

How to manage the interaction:
Although there is a possible interaction between Synerzen Tablet and Ketoconazole, you can take these medicines together if prescribed by a doctor. However, if you experience fever, chills, swollen or painful joints, unexpected bleeding or bruises, skin rash, itching, vomiting, abdominal pain, light-colored stool, dark-colored urine, yellowing of the skin or eyes, decreased hunger, consult the doctor. Do not stop using any medications without talking to the doctor.
Aceclofenac + ParacetamolTeriflunomide
Severe
How does the drug interact with Synerzen Tablet:
Co-administration of Teriflunomide with Synerzen Tablet may increase the risk or severity of Liver problems.

How to manage the interaction:
Taking Synerzen Tablet with Teriflunomide together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, if you experience symptoms such as fever, chills, swollen or painful joints, unexpected bleeding or bruises, skin rash, itching, vomiting, abdominal pain, light-colored stool, dark-colored urine, yellowing of the skin or eyes, decreased hunger, consult the doctor. Do not stop using any medications without talking to the doctor.
Aceclofenac + ParacetamolAtenolol
Severe
How does the drug interact with Synerzen Tablet:
Co-administration of Atenolol with Synerzen Tablet could decrease the action of Atenolol.

How to manage the interaction:
Although there is a possible interaction between Atenolol and Synerzen Tablet, you can take these medicines together if prescribed by a doctor. However, if you experience any unusual symptoms, consult the doctor. Do not discontinue any medications without a doctor's advice.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANALGESIC AND ANTIPYRETIC AGENT]

FAQs

Synerzen Tablet is used to reduce pain and inflammation.

No, Synerzen Tablet does not cure Rheumatoid arthritis but instead, it helps in reducing the pain and inflammation caused by it as it a pain killer.

Yes, Synerzen Tablet is may cause nausea or vomiting in some people. In order to avoid the same, you should take Synerzen Tablet with milk or food. In case you are still experiencing excessive nausea while consuming Synerzen Tablet , speak with your doctor right away.

No, do not suddenly stop taking Synerzen Tablet . If you want to stop taking this medicine, consult your doctor and he might gradually reduce the dose to avoid an unwanted increase in pain or inflammation.

No, Synerzen Tablet should ideally not be taken for stomach pain without consulting a physician. This medication can increase the secretion of stomach acid, which may worsen gastritis or an unknown underlying stomach ulcer.

Patients with mild to moderate renal impairment should be kept under surveillance. The lowest effective dose should be used and renal function monitored regularly. Effects on renal function are usually reversible on withdrawal of Synerzen Tablet .

Yes, let your doctor know if you are taking any other medicine for pain, arthritis or fever. If you experience dark stools, blood in vomit, or stomach pain, stop taking Synerzen Tablet and consult your doctor immediately, as these could be signs of bleeding in your stomach or intestine. Take Synerzen Tablet only for the duration as prescribed by your doctor. Do not take more than the prescribed dose, as it may cause an overdose.

Synerzen Tablet already contains Paracetamol and Aceclofenac. So, avoid taking additional paracetamol. If your pain does not subside, consult your doctor so that they may increase the dose or add another medicine depending on your condition.

Yes, Synerzen Tablet is a painkiller. It contains Aceclofenac and Paracetamol, which helps to relieve pain.

You are recommended to consult your doctor before taking Synerzen Tablet with antibiotics to avoid drug interactions.

Synerzen Tablet is safe if used as advised by the doctor. Follow your doctor’s instructions.

Yes, the use of Synerzen Tablet can cause dizziness (feeling faint, lightheaded, unsteady, or weak) in some patients. If you feel dizzy or lightheaded, take rest for sometime and resume once you feel better.

Synerzen Tablet is contraindicated in patients with known allergy to any of its ingredients or in patients or other painkillers (NSAIDs). Patients with a history of stomach ulcers or active, recurrent stomach ulcer/bleeding should ideally avoid taking Synerzen Tablet . Additionally, patients with a history of high blood pressure, heart failure, and kidney or liver disease, should also avoid taking Synerzen Tablet .

Yes, Synerzen Tablet be taken with vitamin B-complex as it helps to treat vitamin deficiency that may be the cause of underlying pain. However, please consult your doctor before using Synerzen Tablet with other medicines or supplements.

No, taking higher dose of Synerzen Tablet than recommended may cause serious liver damage or allergic reactions such as swelling of the mouth, face and throat; itching; rash or difficulty in breathing. If the pain is not relieved or if you are experience increased severity of pain by the recommended doses, please consult your doctor.

Store Synerzen Tablet at room temperature in a dry place. Protect from sunlight. Keep it out of reach of children.

Synerzen Tablet may take about 1.5 to 3 hours after oral administration to show its effect. However, the time may vary with every individual patient to get the desired results.

The dosage of Synerzen Tablet will be decided by your doctor. Follow doctor’s instructions. Do not take more than the recommended dose.

No, you are not recommended to take Synerzen Tablet along with other painkiller tablets as it may cause unwanted side effects such as stomach ulcers or pain. Therefore, please consult your doctor before taking Synerzen Tablet with other medicines.

Synerzen Tablet is not recommended for children as the safety and efficacy have not been established.

Synerzen Tablet contains Aceclofenac (pain reducer) and Paracetamol (fever reducer) which work by blocking the chemical messengers responsible for causing pain, inflammation, and fever.

Take Synerzen Tablet as advised by your doctor. Swallow it as whole with a glass of water. Do not crush, chew or break it.

Synerzen Tablet may cause side effects such as nausea, dizziness, diarrhoea, flatulence, or constipation. If these side effects persist or worsen, please consult your doctor.

You are preferably advised to take Synerzen Tablet after meals, as food helps to prevent any potential gastric irritation the drug might cause when taken on an empty stomach. Follow doctor’s instructions.

If you forget to take a dose of Synerzen Tablet , take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take the next scheduled dose in the prescribed time. Do not double the dose to make up for the missed one as this may increase the risk of side effects.

You are recommended to consult your doctor before taking other medicines with Synerzen Tablet to avoid drug interactions.

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Country of origin

India

Manufacturer/Marketer address

Healthcare House, 31/4- L Colony, GST Bhavan Road, Near Sahajanand College, Ambawadi, Ahmedabad, Gujarat 380015, INDIA
Other Info - SYN0180
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