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  3. Synernam 1 gm Injection 1's

Synernam 1 gm Injection 1's, Pack of 1 Injection
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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Synernam 1 gm Injection is used to treat bacterial infections. It contains Aztreonam which works by killing the infection-causing bacteria. In some cases, this medicine may cause side effects such as dizziness, headache, sneezing, high temperature, and double vision. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Composition :

AZTREONAM-1000MG

Manufacturer/Marketer :

Alkem Laboratories Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Synernam 1 gm Injection

Synernam 1 gm Injection belongs to a class of antibiotics used in the treatment of serious bacterial infections. A bacterial infection is a condition in which harmful bacteria grows in the body and causes infection. It can infect any part of the body and multiple very quickly.

Synernam 1 gm Injection contains aztreonam, which belongs to a class of monobactam antibiotics. It works by inhibiting the formation of the bacterial cell wall (a protective covering) that is necessary for their survival.

Some common side effects of Synernam 1 gm Injection include dizziness, bad breath, headache, sneezing, high temperature, bleeding of the stomach, double vision. These side effects are not familiar to everyone and vary individually. If you notice any side effects that are not manageable, please consult your doctor.

If you are known to be allergic to Synernam 1 gm Injection or any other medicines, please tell your doctor. Do not receive Synernam 1 gm Injection if you are pregnant or breastfeeding. Consult your doctor immediately if you notice signs of allergic reaction such as swelling of the face, lips, throat, and/or tongue with difficulty in breathing after receiving Synernam 1 gm Injection.

Uses of Synernam 1 gm Injection

Treatment of Bacterial infections

Directions for Use

• Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.• Synernam 1 gm Injection will be administered by the doctor or healthcare professional.• Do not self-administer.

Medicinal Benefits

Synernam 1 gm Injection belongs to the class of monobactam antibiotics. It reduces the infection by inhibiting bacterial growth. It kills the bacteria by disrupting the formation of the cell wall. It irreversibly binds to the proteins in the bacteria that are essential for the formation of the cell membrane.

How Synernam 1 gm Injection Works

Synernam 1 gm Injection contains aztreonam, which belongs to a class of monobactam antibiotics. It works by inhibiting the formation of the bacterial cell wall (a protective covering) that is necessary for their survival.

Storage

Keep Synernam 1 gm Injection out of the sight and reach of children.
Side effects of Synernam 1 gm Injection
  • A blocked nose can be relieved by drinking more water, which helps clear fluids.
  • Use saline nasal spray available over the counter to relieve blockage or blow harder to remove the mucus.
  • Use nasal strips that can be placed on the nose to widen nostrils and increase airflow.
  • Keep a humidifier around to moisten air at home/workplace.
  • If you experience or encounter any severe allergic reaction, stop using medication and consult the doctor right away.
  • Tell your doctor about the allergic reaction, including the medication taken and any symptoms experienced.
  • Your doctor will evaluate the severity of the reaction and determine the best course of action.
  • To ensure a full recovery, follow your doctor's advice, attend scheduled follow-up appointments, and undergo recommended tests to monitor progress and adjust treatment as needed.
Here are the steps to manage angioedema (Swelling Under The Skin) as a side effect of medication:
  • If you experience angioedema, inform your doctor immediately. Treatment can help keep the swelling under control.
  • Seek medical attention if symptoms are severe, such as difficulty breathing or swallowing.
  • Follow your doctor's instructions to manage symptoms, which may include stopping or adjusting the medication that triggered angioedema.
  • Your doctor may also recommend antihistamines, steroids, or other treatments to reduce swelling and inflammation.
  • Make dietary and lifestyle changes as recommended, such as avoiding trigger foods or reducing stress.
  • Monitor your condition closely and track your symptoms to report them to your doctor.
  • Consult your doctor again if symptoms worsen or do not improve or if you experience any new or concerning symptoms.
  • Talk to your doctor about medicines to manage neutropenia based on the underlying cause.
  • Avoid contact with people who are sick.
  • Wash your hands regularly with soap and water.
  • Avoid unpasteurized dairy products.
  • Managing a low platelet count (thrombocytopenia) caused by medication usage requires a multi-step approach. Here are some steps to help manage the condition:
  • Inform your doctor about your low platelet count and medication usage. They will assess the situation and guide the best course of action.
  • Your doctor may recommend adjusting or stopping the medication that is causing a low platelet count. This could involve switching to alternative medication or reducing the dosage.
  • Monitor your platelet count regularly through blood tests to track any changes. This will help the doctor determine the effectiveness of the treatment plan.
  • If an underlying condition, such as infection or inflammation, contributes to the low platelet count, your doctor will treat it.
  • In some cases, alternative treatments like platelet transfusions or medications that stimulate platelet production may be necessary.
  • Avoid risky activities and certain medications; eat a balanced diet with plenty of water to reduce bleeding risk and boost overall health.
  • If you experience severe bleeding or bruising, seek emergency medical attention immediately.
  • Include iron-rich foods like dark leafy vegetables, lean red meat, legumes and fish in your diet.
  • Consume vitamin C-rich foods as they aid iron absorption.
  • Limit tea, cocoa, and coffee as these can slow iron absorption.
  • Exercise regularly; however, do not overdo it.

What if I have taken an overdose of Synernam 1 gm Injection

It is unlikely to overdose on parenteral medication as it is administered by a healthcare professional. However, seek medical attention if you experience any unusual symptoms.

Drug Warnings

Regular monitoring of kidney and liver functioning is recommended while taking Synernam 1 gm Injection. If you are a breastfeeding or pregnant woman, please consult a doctor before taking Synernam 1 gm Injection. If you notice blood in stools or have severe stomach pain with diarrhoea, contact your doctor immediately. Inform your doctor before taking Synernam 1 gm Injection if you have liver problems, kidney problems, blood disorders, fits. Also, inform your doctor if you are already taking medicines like antibiotics or oral anticoagulants. 

Drug-Drug Interactions

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AztreonamCholera, live attenuated
Severe
AztreonamBCG vaccine
Severe

Drug-Drug Interactions

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AztreonamCholera, live attenuated
Severe
How does the drug interact with Synernam 1 gm Injection:
Coadministration of Synernam 1 gm Injection with Cholera vaccine can reduce the effects of Cholera vaccine.

How to manage the interaction:
Taking Synernam 1 gm Injection with Cholera vaccine together can result in an interaction, but it can be taken if your doctor has advised it. Do not stop using any medications without first talking to your doctor.
AztreonamBCG vaccine
Severe
How does the drug interact with Synernam 1 gm Injection:
When BCG vaccine is used together with Synernam 1 gm Injection, its effectiveness may be reduced.

How to manage the interaction:
There may be a possibility of interaction between Synernam 1 gm Injection and BCG vaccine, but it can be taken if prescribed by a doctor. Do not stop using any medications without first talking to your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Take probiotics after completing the full course of Synernam 1 gm Injection to restore some healthy bacteria in the intestines that may have been killed. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhoea. Certain fermented foods like cheese, yoghurt, kombucha, sauerkraut and kimchi can help to restore the good bacteria of the intestine.
  • Include fibre rich foods, as they can be easily digested by your gut bacteria, which helps stimulate their growth. Thus, fibre rich foods may help restore healthy gut bacteria after a course of antibiotics. Whole grains such as whole-grain bread, brown rice should be included in your diet.
  • Make sure you drink plenty of water or other fluids every day while you are taking Synernam 1 gm Injection.

Habit Forming

No

Therapeutic Class

ANTIBIOTICS

Synernam 1 gm Injection Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Caution

The interaction of alcohol with Synernam 1 gm Injection is unknown. Please consult a doctor before consuming alcohol while using Synernam 1 gm Injection.

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Pregnancy

Caution

The safety of Synernam 1 gm Injection in pregnant women is unknown. Therefore, it is given to pregnant women only if the doctor thinks the benefits outweigh the risks.

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Breast Feeding

Caution

Synernam 1 gm Injection is excreted in human milk. Therefore, it is given to breastfeeding mothers only if the doctor thinks benefits are greater than risks.

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Driving

Caution

Synernam 1 gm Injection cause double vision, dizziness as a side effect. So, avoid driving after receiving Synernam 1 gm Injection.

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Liver

Caution

Take Synernam 1 gm Injection with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Take Synernam 1 gm Injection with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Caution

Synernam 1 gm Injection can be given safely to children, dose to be adjusted and recommended by a child specialist only.

Have a query?

FAQs

Synernam 1 gm Injection contains Aztreonam, an antibiotic that works by interfering with the formation of the bacterial cell wall (a protective covering) that is necessary for their survival. Thereby damages the bacterial cell wall and kills bacteria.

No. You should complete the full course of Synernam 1 gm Injection as prescribed by your doctor. After completing the full course of Synernam 1 gm Injection will work. It is important that you take Synernam 1 gm Injection at the right dose, right times, and for the right numbers of days.

Synernam 1 gm Injection does not work against viral infection. So, it should not be taken to treat common cold cough and cough

Synernam 1 gm Injection may cause dizziness and double vision. So, drive only if you are alert and avoid driving and operating machinery if you feel dizzy or experience vision changes.

Synernam 1 gm Injection is used in the treatment of serious bacterial infections that require injectable antibiotics. Synernam 1 gm Injection targets infections across different areas of the body and may be used in combination with other antibiotics when necessary.

Synernam 1 gm Injection will be administered by a healthcare professional in a hospital or clinic setting. Synernam 1 gm Injection will either be given directly into your vein (IV) or as an infusion. Alternatively, Synernam 1 gm Injection can also be injected into a large muscle, such as the buttocks or thigh, depending on your condition and a physician's recommendation. The method of administration will be determined by your doctor to ensure the correct dosage and effectiveness.

Synernam 1 gm Injection may be safe for patients who are allergic to penicillin as Synernam 1 gm Injection is a monobactam antibiotic, which is chemically different from penicillins and has shown no significant cross-reactivity in patients with penicillin allergies. However, as with any medication, it is important to inform your doctor about any known allergies before use to ensure safety.

Synernam 1 gm Injection causes side effects such as dizziness, chest pain, headache, double vision, bad breath, vaginal irritation, and a blocked nose. However, please contact a doctor if these side effects worsen or persist longer.

Country of origin

India

Manufacturer/Marketer address

Alkem Laboratories Limited, Devashish Building, Alkem House, Senapati Bapat Road, Lower Parel, Mumbai - 400 013.
Other Info - SYN0402

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Author Details

Veda MaddalaDoctor badge

Written By

Veda Maddala

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 18, 2025 | 6:51 AM IST

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Reference

  1. https://www.medicines.org.uk/emc/files/pil.3773.pdf

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