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  3. Sutib 50 Capsule 7's

Sutib 50 Capsule 7's, Pack of 7 CapsuleS
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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Sutib 50 Capsule is used to treat cancer of the stomach, bowel, oesophagus, kidney, and hormone-producing cells in the pancreas. It contains sunitinib which works by slowing down the growth of cancer cells. In some cases, this medicine may cause side effects such as dry mouth, stomach upset, nausea, vomiting, diarrhoea, constipation, and loss of appetite. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Composition :

SUNITINIB-50MG

Manufacturer/Marketer :

Glenmark Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Sutib 50 Capsule

Sutib 50 Capsule belongs to the class of medications called ‘antineoplastic agents’ used in treating gastrointestinal stromal tumors (cancer of the stomach, bowel, or esophagus) in which patients don’t respond to imatinib (another anticancer agent). It is also used to treat renal carcinoma (kidney cancer) that has spread to other parts of the body and advanced pancreatic neuroendocrine tumors (cancer that has affected hormone-producing cells in the pancreas).

Sutib 50 Capsule contains sunitinib. It acts by slowing down the growth of cancer cells by two processes. It interferes with the action of a protein that promotes cell division and thereby decreases cancer cell production. It can inhibit a process called angiogenesis, the development of blood supply to the cancer cells. This effect inhibits the nutrient supply to the cancer cells, thereby causing cancer cell death eventually.

You should take this medicine exactly as prescribed by the doctor. The common side-effects of Sutib 50 Capsule are difficulty breathing, increase in blood pressure, extreme tiredness, swelling caused by fluid under the skin and around the eye, pain or irritation in the mouth, mouth sores, dry mouth, taste disturbances, upset stomach, nausea, vomiting, diarrhea, constipation, abdominal pain, loss of appetite, decreased activity of thyroid gland (hypothyroidism), dizziness, headache, nose bleeding, back pain, joint pain, pain in arms and legs, yellowish discoloration of the skin, rash on the palms of the hands and soles of the feet, dryness of the skin, cough, fever, and difficulty to sleep. Inform your doctor immediately if any of these side-effects persist or get worse.

It is not recommended to take Sutib 50 Capsule if you are allergic to any contents of it. Sutib 50 Capsule should be used with caution in patients with high blood pressure, heart problems, diabetes, liver or kidney problems, skin disorders, pancreas or gallbladder problems, history of blood clots, aneurysm (weakening of blood vessel wall), problems with the thyroid gland, pancreas, and gallbladder, liver or kidney problems, and thrombotic microangiopathy (damage to the smallest blood vessels). It is not recommended for use in children and adolescents under 18 years of age. It should be used with caution in pregnant and breastfeeding women. Do not consume alcohol as it may increase the risk of side-effects. Sutib 50 Capsule may cause dizziness, so do not drive or operate heavy machinery if you are not fully alert.

Uses of Sutib 50 Capsule

Treatment of Gastrointestinal stromal cancer, kidney cancer, and pancreatic neuroendocrine tumors.

Directions for Use

• Take Sutib 50 Capsule with or without food as advised by your doctor.• Typically, Sutib 50 Capsule is taken once daily for 28 days, followed by a 2-week break. This cycle is repeated every 6 weeks, as recommended by your doctor. However, always follow your doctor's instructions regarding dosage and duration.• Swallow the capsule as a whole with a glass of water.• Do not open, crush or dissolve Sutib 50 Capsule.

Medicinal Benefits

Sutib 50 Capsule is a targeted therapy used to treat advanced kidney cancer. It is also used in patients with kidney cancer to prevent recurrence after having kidney surgery. It is used to treat gastrointestinal stromal cancer that cannot be treated with imatinib, another anti-cancer medicine. It is used to manage pancreatic neuroendocrine tumors (cancer of hormone-producing cells of the pancreas) that cannot be treated with surgery. Sutib 50 Capsule can help to manage the above conditions if taken regularly as prescribed by the doctor.

How Sutib 50 Capsule Works

Sutib 50 Capsule contains sunitinib. It acts by slowing down the growth of cancer cells by two processes. It interferes with the action of a protein that promotes cell division and thereby decreases cancer cell production. It can inhibit a process called angiogenesis, the development of blood supply to the cancer cells. This effect inhibits the nutrient supply to the cancer cells, thereby causing cancer cell death eventually.
Side effects of Sutib 50 Capsule
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
Here's a comprehensive approach to managing medication-triggered fever:
  • Inform your doctor immediately if you experience a fever after starting a new medication.
  • Your doctor may adjust your medication regimen or dosage as needed to minimize fever symptoms.
  • Monitor your body temperature to monitor fever progression.
  • Drink plenty of fluids, such as water or electrolyte-rich beverages, to help your body regulate temperature.
  • Get plenty of rest and engage in relaxation techniques, such as deep breathing or meditation, to help manage fever symptoms.
  • Under the guidance of your doctor, consider taking medication, such as acetaminophen or ibuprofen, to help reduce fever.
  • If your fever is extremely high (over 103°F), or if you experience severe symptoms such as confusion, seizures, or difficulty breathing, seek immediate medical attention.
  • Rest well; get enough sleep.
  • Wear comfortable layers of clothes and get to a warm place.
  • Drink warm fluids like coffee, tea or hot chocolate.
  • Warm up using a blanket or heating pad.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.

What if I have taken an overdose of Sutib 50 Capsule

Take Sutib 50 Capsule only as prescribed by the physician. Do not exceed the recommended dose, as it might cause an overdose. If you suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

Sutib 50 Capsule may cause an increase in blood pressure. So, your doctor may monitor your blood pressure regularly and prescribe blood-pressure-lowering medicines if necessary. Sutib 50 Capsule may increase the risk of bleeding, and the risk is high if you are taking any blood thinners such as warfarin and acenocoumarol. Sutib 50 Capsule may cause heart problems, so notify your doctor if you experience extreme tiredness, shortness of breath, and swelling of the feet and ankles. Sutib 50 Capsule may cause heart rhythm abnormalities, so inform your doctor if you experience dizziness or abnormal heartbeats. Sutib 50 Capsule should be used with caution in patients with a recent history of blood clots, heart attack, or stroke as this medicine may cause chest pain, shortness of breath, difficulty speaking, weakness of one side of the body, or dizziness. Sutib 50 Capsule should be used with caution in patients with aneurysm (weakening of blood vessel wall), thrombotic microangiopathy (damage to the small blood vessels), and liver or kidney problems. Sutib 50 Capsule may cause inflammation of the pancreas or gallbladder and lead to symptoms such as abdominal pain (upper abdominal region), fever, and vomiting, in patients with a history of pancreatic or gallbladder disorders. Sutib 50 Capsule may cause thyroid gland problems, so inform your doctor if you experience frequent fatigue and extreme cold than others. Sutib 50 Capsule may cause skin ulceration (pyoderma gangrenosum) or infection (necrotizing fasciitis). So, inform your doctor if you notice symptoms of infection around a skin injury such as fever, pain, swelling, redness, and drainage of pus or blood from the wound. However, these effects are usually reversible after the discontinuation of therapy. If you develop severe skin rashes, especially with blistering or peeling of the skin, notify your doctor immediately as it can be a sign of a serious skin condition. Sutib 50 Capsule may cause headaches, high blood pressure, and vision problems in patients with a history of fits or seizures. While using Sutib 50 Capsule, blood sugar levels should be monitored regularly in patients with diabetes. In addition, notify your doctor immediately if you notice signs of low blood sugar such as fatigue, hunger, sweating, pounding heartbeat, and loss of consciousness.

Drug-Drug Interactions

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SunitinibEfavirenz
Severe
SunitinibImipramine
Severe

Drug-Drug Interactions

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SunitinibEfavirenz
Severe
How does the drug interact with Sutib 50 Capsule:
Taking Efavirenz and Sutib 50 Capsule can increase the risk or severity of irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Efavirenz and Sutib 50 Capsule together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
SunitinibImipramine
Severe
How does the drug interact with Sutib 50 Capsule:
Taking Imipramine with Sutib 50 Capsule can increase the risk or severity of irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Imipramine with Sutib 50 Capsule together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
SunitinibAmiodarone
Severe
How does the drug interact with Sutib 50 Capsule:
Coadministration of Amiodarone with Sutib 50 Capsule can lead to or increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Amiodarone with Sutib 50 Capsule together is avoided as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
SunitinibCarbamazepine
Severe
How does the drug interact with Sutib 50 Capsule:
Taking Sutib 50 Capsule with carbamazepine together may reduce the blood levels of Sutib 50 Capsule, which may make the medication less effective

How to manage the interaction:
Although taking carbamazepine and Sutib 50 Capsule together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
SunitinibDexamethasone
Severe
How does the drug interact with Sutib 50 Capsule:
Taking Dexamethasone may lower the blood levels of Sutib 50 Capsule in some patients, making the medication less effective.

How to manage the interaction:
Although there is a possible interaction, Dexamethasone can be taken with Sutib 50 Capsule if prescribed by the doctor. Do not discontinue the medication without consulting a doctor.
SunitinibSotalol
Severe
How does the drug interact with Sutib 50 Capsule:
Using sotalol together with Sutib 50 Capsule can increase the risk of an irregular heart rhythm. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Although there is a possible interaction between Sotalol and Sutib 50 Capsule, you can take these medicines together if prescribed by a doctor. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
SunitinibAmisulpride
Severe
How does the drug interact with Sutib 50 Capsule:
Taking amisulpride with Sutib 50 Capsule increases the risk of an abnormal heart rhythm.

How to manage the interaction:
Although taking amisulpride along with Sutib 50 Capsule can result in an interaction, it can be taken if a doctor has advised it. However, if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
SunitinibChloroquine
Severe
How does the drug interact with Sutib 50 Capsule:
Using chloroquine together with Sutib 50 Capsule can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking chloroquine and Sutib 50 Capsule together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
SunitinibNilotinib
Severe
How does the drug interact with Sutib 50 Capsule:
Combining Sutib 50 Capsule and nilotinib can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Sutib 50 Capsule and nilotinib together can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, heart palpitations, diarrhea, or vomiting, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
SunitinibCeritinib
Severe
How does the drug interact with Sutib 50 Capsule:
Taking Sutib 50 Capsule with ceritinib can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Taking Ceritinib with Sutib 50 Capsule together can possibly result in an interaction, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat a healthy diet that includes fresh fruits and vegetables.
  • Include leafy vegetables, citrus fruits, fatty fish, berries, yogurt, apples, peaches, cauliflower, cabbage, broccoli, beans, herbs in your diet.
  • Avoid fast food, fried food, processed meats, refined carbs, and added sugars.
  • Maintain a healthy weight.
  • Avoid smoking and alcohol consumption.
  • Manage stress and use relaxation techniques such as meditation and yoga.
  • Get optimal sleep, rest well.
  • Limit exposure to environmental toxins such as smoke, asbestos, or other chemicals.

Habit Forming

No

Therapeutic Class

ANTINEOPLASTIC

Sutib 50 Capsule Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Caution

Do not consume alcohol as it can increase the risk of side-effects.

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Pregnancy

Unsafe

Sutib 50 Capsule may cause harmful effects to the unborn baby when used in pregnant women. It is also advised to use reliable contraception to prevent pregnancy while using this medicine.

bannner image

Breast Feeding

Unsafe

Sutib 50 Capsule may cause harmful effects to the nursing baby when given to breastfeeding mothers. Consult your doctor before using Sutib 50 Capsule.

bannner image

Driving

Caution

Sutib 50 Capsule may cause dizziness, so do not drive or operate heavy machinery if you feel dizzy.

bannner image

Liver

Caution

Sutib 50 Capsule should be used with caution in patients with liver diseases. The doctor may monitor liver function during the treatment.

bannner image

Kidney

Caution

Sutib 50 Capsule should be used with caution in patients with kidney diseases. The doctor may monitor kidney function during the treatment.

bannner image

Children

Unsafe

Sutib 50 Capsule is not recommended for children and adolescents below the age of 18 years.

Have a query?

FAQs

Sutib 50 Capsule is used to treat gastrointestinal stromal tumours (cancer of the stomach, bowel, or oesophagus), renal carcinoma (kidney cancer) and advanced pancreatic neuroendocrine tumours (cancer that has affected hormone-producing cells in the pancreas).

Sutib 50 Capsule contains sunitinib which is an anti-cancer medicine. It acts by slowing down the growth of cancer cells by two processes. It interferes with the action of a protein that promotes cell division and thereby decreases cancer cell production. It can inhibit a process called angiogenesis, the development of blood supply to the cancer cells. This effect inhibits the nutrient supply to the cancer cells, thereby causing cancer cell's death eventually.

Sutib 50 Capsule may cause thyroid dysfunction leading to decreasing in thyroid hormone levels. This effect cause hypothyroidism or underactive thyroid. So, notify your doctor if you feel extreme tiredness, colder than others, or change in voice while using this medicine.

Sutib 50 Capsule is not a cure for cancer. It can slow down cancer progression and prevent the spread of cancer cells to other parts of the body. Also, the effects of the medicine differ for each patient based on age and health history.

Sutib 50 Capsule can be taken as long as it is prescribed to you. The duration of the therapy is determined by the doctor based on your health condition.

Yes, Sutib 50 Capsule is considered chemotherapy. It is used to treat stomach cancer, advanced kidney cancer, and pancreatic neuroendocrine tumors (cancer of the pancreas's hormone-producing cells).

It is not known whether Sutib 50 Capsule can be taken with other chemotherapy medicines. So, please consult a doctor for advice.

Take Sutib 50 Capsule with or without food as prescribed by your doctor. Swallow it as a whole with a glass of water. Do not chew or break it. Do not exceed the recommended dose.

Sutib 50 Capsule may make your skin lighter and may also cause hair loss. Other skin-related effects include dryness, thickening, cracking, blisters, or rashes, particularly on the palms and soles. These side effects are usually reversible and resolve once Sutib 50 Capsule is stopped. Sutib 50 Capsule may cause severe skin reactions, such as a serious rash or rapidly spreading skin ulcers, which could be life-threatening. Therefore, if you experience any of these side effects, please consult your doctor immediately.

Sutib 50 Capsule may cause serious liver problems, including potentially fatal complications. It is important to contact your doctor immediately if you notice symptoms such as itching, yellowing of the skin or eyes, dark urine, or pain in the upper right abdomen. To ensure your safety, your doctor will conduct blood tests to monitor liver function both before starting Sutib 50 Capsule and throughout the treatment.

No, generics are not available for Sutib 50 Capsule.

Sutib 50 Capsule may reduce blood sugar levels. So, diabetic patients should be cautious as it may cause very low blood sugar resulting in unconsciousness. Also, regularly monitor blood sugar levels. Consult your doctor immediately if you experience symptoms of low blood sugar, such as fatigue, palpitations, sweating, hunger, or loss of consciousness

Sutib 50 Capsule may increase blood pressure. Your doctor will monitor your blood pressure during treatment and may prescribe medicines to help control it if necessary.

Sutib 50 Capsule may cause side effects such as tiredness, pain, irritation, mouth sores, dry mouth, upset stomach, joint pain, back pain, abdominal pain, nausea, vomiting, loss of appetite, dryness of skin, cough, fever, and sleep difficulty. These do not require any medical treatment as they will gradually reduce over time. Consult, your doctor if these side effects persist longer.

Country of origin

India

Manufacturer/Marketer address

Glenmark Pharmaceuticals Limited, B/2, Mahalaxmi Chambers, 22, Bhulabhai Desai Road, Mumbai €“ 400 026.
Other Info - SUT0082

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Author Details

Santoshini Reddy GDoctor badge

Written By

Santoshini Reddy G

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 18, 2025 | 6:50 AM IST

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Reference

  1. https://www.medicines.org.uk/emc/files/pil.227.pdf

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