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compositionComposition:SUGAMMADEX-100MG/ML
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Prescription Medicine
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Sugmadex Injection 2 ml is used to speed up recovery from muscle relaxants after surgery. Sugmadex Injection 2 ml contains sugammadex, which works by binding to muscle relaxants, neutralizing their effect. This helps your muscles start working normally again, and you can breathe properly. In some cases, you may experience side effects such as flushing (warmth, redness, or tingly feeling), itching, slow heartbeats, nausea, vomiting, pain, headache, light-headed feeling, cough, decreased blood pressure, injection site reactions, and shortness of breath. Let the doctor know if you are taking any other medicines or have any medical conditions.

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Written By ,
Reviewed By Praneetha Akunuri , M.Pharmacy
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More about the Product

Composition :

SUGAMMADEX-100MG/ML

Manufacturer/Marketer :

VARENYAM HEALTHCARE PVT LTD

Consume Type :

Parenteral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Sugmadex Injection 2 ml

Sugmadex Injection 2 ml is a specialised injection used at the end of surgery to reverse the effects of certain muscle relaxants. This medication helps restore normal muscle function, allowing you to breathe easily on your own and recover more quickly from general anaesthesia. It is typically injected by anaesthesia professionals in a hospital operating room.

Because Sugmadex Injection 2 ml is a one-time injection given only during your surgical procedure, it does not require a daily schedule or consistent home use. It is injected directly into a vein, so having food in your stomach does not change how the medicine works. Following your surgical team's recovery diet and resting as instructed will help you get the best recovery results.

While most patients recover from anaesthesia without issues, some may experience mild, temporary side effects like nausea, vomiting, headache, or pain where the needle went in. You should immediately tell your medical team if you notice any unusual symptoms, such as severe dizziness, breathing difficulties, or skin rashes. Your medical team will closely monitor you to manage any immediate reactions.

Tell your doctor before your surgery if you have ever had severe kidney problems or liver damage. Do not take this if you have had a severe allergic reaction to this medication in the past.

This injection can temporarily stop your hormonal birth control from working, so you must use a non-hormonal backup method for seven days after receiving it. Please discuss your health history with your doctor if you are pregnant, breastfeeding, or an older adult, as they will tailor your recovery plan to keep you safe. Avoiding alcohol during your immediate recovery is also important to prevent extreme drowsiness.

Uses of Sugmadex Injection 2 ml

Sugmadex Injection 2 ml is used at the end of surgery to reverse the effects of certain muscle relaxants. The detailed uses of Sugmadex Injection 2 ml are as follows:

  • Reversal of muscle relaxants: Sugmadex Injection 2 ml helps by rapidly undoing the effects of certain muscle-paralysing medicines used during general anaesthesia.
  • Breathing recovery after surgery: This medication helps your breathing muscles recover quickly so that your breathing tube can be safely removed sooner.

Key Benefits

Sugmadex Injection 2 ml helps reverse the effects of certain muscle relaxants used during surgery, allowing normal muscle function to return quickly after anaesthesia. When administered by a healthcare professional, it helps restore breathing and muscle strength, supporting a safe and smooth recovery.

  • Rapidly Reverses Muscle Relaxation: By reversing the effects of muscle relaxants, this medicine helps restore normal breathing, swallowing, speaking, and muscle movement much faster after surgery.
  • Supports Safer Recovery After Anaesthesia: Early recovery of muscle function reduces the risk of post-operative breathing difficulties and other complications associated with residual muscle relaxation.
  • Promotes Faster Recovery: By helping you regain normal muscle function sooner, this medicine can reduce the time spent in the recovery room and support a more comfortable transition after anaesthesia.
Side effects of Sugmadex Injection 2 ml
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
  • Apply a hot/cold pack to the affected area.
  • Doing gentle exercises can help cope with pain by stretching muscles.
  • Get enough sleep. It helps enhance mood and lower pain sensitivity.
  • Avoid alcohol, smoking and tobacco as they can increase pain.
  • Follow a well-balanced meal.
  • Meditation and massages may also help with pain.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
Managing Low Blood Pressure Triggered by Medication: Expert Advice:
  • If you experience low blood pressure symptoms like dizziness, lightheadedness, or fainting while taking medication, seek immediate medical attention.
  • Make lifestyle modifications and adjust your medication regimen under medical guidance to manage low blood pressure.
  • As your doctor advises, regularly check your blood pressure at home. Record your readings to detect any changes and share them with your doctor.
  • Fluid intake plays a vital role in managing blood pressure by maintaining blood volume, regulating blood pressure, and supporting blood vessel function. Drinking enough fluids helps prevent dehydration, maintain electrolyte balance, and regulate fluid balance.
  • Take regular breaks to sit or lie down if you need to stand for long periods.
  • When lying down, elevate your head with extra pillows to help improve blood flow.
  • Avoid heavy exercise or strenuous activities that can worsen low blood pressure.
  • Wear compression socks as your doctor advises to enhance blood flow, reduce oedema, and control blood pressure.
  • If symptoms persist or worsen, or if you have concerns about your condition, seek medical attention for personalized guidance and care.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Here are the few steps for dealing with itching caused by drug use:
  • Report the itching to your doctor immediately; they may need to change your medication or dosage.
  • Use a cool, damp cloth on the itchy area to help soothe and calm the skin, reducing itching and inflammation.
  • Keep your skin hydrated and healthy with gentle, fragrance-free moisturizers.
  • Try not to scratch, as this can worsen the itching and irritate your skin.
  • If your doctor prescribes, you can take oral medications or apply topical creams or ointments to help relieve itching.
  • Track your itching symptoms and follow your doctor's guidance to adjust your treatment plan if needed. If the itching persists, consult your doctor for further advice.
  • Avoid trigger foods that can cause allergic reactions, such as nuts, shellfish, or dairy products.
  • Keep a food diary to track potential food allergens.
  • Include omega-3 rich foods like salmon and walnuts to reduce inflammation.
  • Wear loose, comfortable clothing made from soft fabrics like cotton.
  • Apply cool compresses or take cool baths to reduce itching.
  • Use gentle soaps and avoid harsh skin products.
  • Reduce stress through relaxation techniques like meditation or deep breathing.

Directions for Use

  • Follow your doctor’s instructions on the dosage and timing of this medication to ensure safe and effective use.
  • Sugmadex Injection 2 ml should be administered by a nurse or doctor to ensure proper dosage, technique, and monitoring for any potential side effects or complications.
  • Do not self-administer.

How Sugmadex Injection 2 ml Works

During surgery, muscle relaxants are injected to keep your body still. Sugmadex Injection 2 ml contains sugammadex, which works like a microscopic net in your blood. It seeks out the molecules of the muscle relaxant medicine and wraps tightly around them, creating a secure bond. Once the muscle relaxant is trapped inside this biological net, it can no longer attach to your muscle receptors. Your body then filters the trapped medicine through your kidneys, allowing you to pass it out safely in your urine. This process restores your muscle control in just a few minutes.
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Alcohol

Caution

It is unknown whether alcohol interacts with Sugmadex Injection 2 ml. However, it is best to avoid or limit alcohol consumption to avoid any negative complications.

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Pregnancy

Caution

Sugmadex Injection 2 ml is given to pregnant women only if the doctor thinks the benefits outweigh the risks.

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Breast Feeding

Consult your doctor

It is unknown whether Sugmadex Injection 2 ml passes into breast milk, so consult your doctor before using it while breastfeeding.

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Driving

Consult your doctor

Your doctor will advise when it is safe to drive or operate machinery after using Sugmadex Injection 2 ml.

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Liver

Caution

If you have an existing or a history of liver disease, inform your doctor before receiving Sugmadex Injection 2 ml.

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Kidney

Caution

If you have a history of kidney disease, inform your doctor before receiving Sugmadex Injection 2 ml. Dose adjustment may be needed to avoid potential effects.

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Children

Consult your doctor

Sugmadex Injection 2 ml is not recommended in children aged less than two years. Your doctor may prescribe this medicine if required based on your child's age, body weight, and condition.

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Heart

Caution

If you have an existing or a history of heart disease, inform your doctor before receiving Sugmadex Injection 2 ml.

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Geriatrics

Caution

Sugmadex Injection 2 ml should be used with caution in elderly patients. Please consult your doctor before use.

What if I have taken an overdose of Sugmadex Injection 2 ml

Because this medication is carefully measured and injected by trained anaesthesia professionals in a hospital, an overdose is extremely rare. If an excess amount is injected, the medical team is equipped to monitor your breathing and heart rate closely and provide immediate supportive care.

Diet & Lifestyle Advise

  • Use backup birth control: If you use hormonal contraceptives (such as pills, patches, rings, or implants), use a non-hormonal barrier method (like condoms) for the next 7 days, as Sugmadex Injection 2 ml can temporarily make your birth control less effective.
  • Protect your kidneys: Drink plenty of water during your recovery period once your doctor says it is safe to do so, as your kidneys need to filter this medicine out of your system.
  • Follow surgical diet guidelines: Stick to light, easy-to-digest foods immediately after surgery to avoid nausea as your stomach and muscles wake up.
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Have a query?

How Soon It Starts Working

The time required for Sugmadex Injection 2 ml to start to work: Sugmadex Injection 2 ml shows its action within a few minutes of administration. The time for which the effects of Sugmadex Injection 2 ml last: Sugmadex Injection 2 ml effect usually lasts for approximately a few hours.

What if you forget to take Sugmadex Injection 2 ml

Since this medicine is injected as a single dose by a healthcare provider during surgery, there is no daily schedule and no risk of missing a dose.

Storage

• It must be stored at a controlled room temperature between 20°C and 25°C (68°F to 77°F).

Drug Warnings

  • Tell your anaesthesia provider about all medications you use, especially birth control, before you undergo surgery.
  • Inform your medical team if you have severe kidney disease, as this medicine might not be recommended for you.
  • Your healthcare provider must check the vial before use; the solution must be clear, colourless-to-light-yellow, and free of floating particles.
  • Alert your nurse or doctor immediately if you feel your heart rate slowing down, feel dizzy, or notice your muscle weakness returning after waking up.

Drug-Drug Interactions

verifiedApollotooltip
  • Hormonal contraceptives (such as birth control pills, rings, patches, or implants): Receiving Sugmadex Injection 2 ml is like missing a daily dose of your hormonal birth control. You must use a backup non-hormonal contraceptive method for 7 days to prevent pregnancy.
  • Toremifene: This breast cancer medicine may delay or reduce the effectiveness of Sugmadex Injection 2 ml in reversing muscle relaxation.
SugammadexLevonorgestrel
Severe
SugammadexMedroxyprogesterone
Severe

Drug-Drug Interactions

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SugammadexLevonorgestrel
Severe
How does the drug interact with Sugmadex Injection 2 ml:
Taking Levonorgestrel and Sugmadex Injection 2 ml may reduce the blood levels and effects of levonorgestrel.

How to manage the interaction:
Although there is a possible interaction between Sugmadex Injection 2 ml and Levonorgestrel, you can take these medicines together if prescribed by a doctor. Your doctor can recommend other options that won't cause any problems when taken together. Do not stop using any medications without talking to a doctor.
SugammadexMedroxyprogesterone
Severe
How does the drug interact with Sugmadex Injection 2 ml:
When medroxyprogesterone is taken with Sugmadex Injection 2 ml, the effect of medroxyprogesterone in the blood may decrease.

How to manage the interaction:
Taking Sugmadex Injection 2 ml with Medroxyprogesterone together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience any unusual symptoms consult your doctor immediately. Do not discontinue any medications without first consulting your doctor.

Drug-Food Interactions

verifiedApollotooltip

No clinically significant food interactions are known with Sugmadex Injection 2 ml when used as directed.

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[MISCELLANEOUS]

FAQs

You are typically asleep under general anaesthesia when this medicine is injected, so you will not feel it. You may feel minor soreness at the IV site when you wake up. Talk to your doctor or nurse if you feel pain after surgery.
Yes, Sugmadex Injection 2 ml can temporarily lower the effectiveness of hormonal birth control, including pills, patches, vaginal rings, and implants. You must use a non-hormonal backup method (like condoms) for the next 7 days. Talk to your doctor or pharmacist for more advice.
It is safe for mild to moderate kidney issues, but it is not recommended if you have severe kidney damage or are on dialysis, as your body will struggle to clear the medicine. Talk to your doctor about your kidney health before surgery.
After binding to the muscle relaxants, the combined medicine is filtered out of your blood by your kidneys and safely passed out in your urine. Talk to your doctor if you want to understand how your body clears medications.
Yes, serious allergic reactions can occur, though they are rare. Your anaesthesia team monitors you constantly and is fully prepared to treat any reactions immediately in the operating room. Talk to your doctor if you have a history of severe allergies.
Yes, Sugmadex Injection 2 ml is safe for elderly patients, though doctors will evaluate your kidney health first since kidney function naturally declines with age. Talk to your doctor if you have concerns about anaesthesia safety.
No, Sugmadex Injection 2 ml does not cause drowsiness; it only targets and reverses muscle relaxation. Any sleepiness you feel after surgery is due to the other anaesthetic medicines wearing off. Talk to your doctor or recovery nurse if you feel overly tired.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

Ground & 1st Floor, Tower-H, Sunwelkin, Near IOC Petrol Pump, Harni, Vadodara-390022, Gujarat, India
Other Info - SUG0202

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