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Stemetil Injection 10 x 1 ml contains prochlorperazine used in the treatment of schizophrenia, acute mania and short-term treatment of anxiety, nausea and vomiting, vertigo (dizziness). It belongs to the class of antipsycotics which works by inhibiting dopamine receptors.

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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Manufacturer/Marketer :

Nicholas Piramal India Ltd

Consume Type :

Parenteral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Stemetil Injection 10 x 1 ml

Stemetil Injection 10 x 1 ml is a prescription injection used to treat severe nausea and vomiting caused by surgery, chemotherapy, or other medical conditions. It is also used to manage severe feelings of anxiety or mental health conditions like schizophrenia. This medicine helps calm overactive nerve signals in the brain to provide fast relief.

Since this medicine is given as an injection, a healthcare professional will determine how often you receive it based on your symptoms. It is usually injected on a regular schedule for consistent symptom control, but can also be used as a single dose for sudden sickness. Because it is injected, it does not depend on food, but drinking plenty of water and eating small, bland meals can help support your recovery. Incorporating stress-reduction techniques and getting plenty of rest also help improve your results.

While using Stemetil Injection 10 x 1 ml , you may experience common side effects such as drowsiness, dry mouth, or mild dizziness. These are usually temporary, but you should contact your doctor right away if you experience muscle stiffness, uncontrollable movements, or a sudden fever. Your healthcare provider can help manage these symptoms or adjust your treatment if needed.

Before starting this medicine, talk to your doctor if you have liver damage, heart disease, or glaucoma. Do not take this if you are in a deep sleep, have consumed large amounts of alcohol, or have had a severe allergic reaction to similar medicines in the past. It is also not suitable for patients with severe bone marrow depression.

This medicine can interact with other drugs like sleeping pills or strong pain relievers, which can make you dangerously sleepy. You should also avoid alcohol and smoking while using this medicine, as they can worsen dizziness and affect how the drug works in your body. If you are pregnant, breastfeeding, or an older adult, consult your doctor before receiving this medicine to ensure it is safe for you.

Uses of Stemetil Injection 10 x 1 ml

Stemetil Injection 10 x 1 ml is used to treat severe nausea and vomiting caused by surgery. The detailed uses of Stemetil Injection 10 x 1 ml are as follows:

  • Severe nausea and vomiting: Stemetil Injection 10 x 1 ml helps by blocking the chemical signals in your brain's vomiting centre, quickly stopping feelings of sickness caused by surgery, migraines, or chemotherapy.
  • Schizophrenia: It helps manage symptoms like hallucinations, delusions, and severe confusion by balancing chemical messengers in the brain.
  • Short-term severe anxiety: It helps calm the nervous system to relieve extreme worry, tension, or agitation when other treatments are not suitable.
  • Severe dizziness (vertigo): It helps control the spinning sensation and associated nausea caused by inner ear problems.

Key Benefits

Stemetil Injection 10 x 1 ml provides fast and effective relief from severe nausea, vomiting, and other conditions requiring rapid treatment through injectable administration. By delivering the medicine directly into the bloodstream, it helps control symptoms quickly and supports a smoother recovery.

  • Provides Rapid Symptom Relief: Because this medicine is administered by injection, it bypasses the digestive system and begins working quickly, making it especially useful for patients who are unable to take or retain oral medicines.
  • Controls Severe Nausea and Vomiting: This medicine helps relieve persistent nausea and vomiting, helping prevent dehydration, allowing you to stay hydrated, rest comfortably, and recover more effectively.
  • Supports Mental Health Stabilisation: When prescribed for certain psychiatric conditions, this medicine helps reduce severe agitation, anxiety, and other distressing symptoms, promoting a calmer state and supporting appropriate medical management.
Side effects of Stemetil Injection 10 x 1 ml
  • Boost your immunity by including immune rich foods in your diet and always remember to stay hydrated.
  • Get sufficient sleep and manage stress which helps in improving white blood cell count.
  • Consult your doctor for an effective treatment to improve the blood cell count and get regular body check up to monitor changes in the count.
  • Try to prevent the factors that cause a decrease in white blood cells which may lead to impaired immunity.
  • Uncontrolled and involuntary movements need immediate medical attention.
  • Observe your movements and try to understand and control the particular movement.
  • Regularly do strengthening exercises to improve blood flow throughout the body and avoid involuntary movements.
  • Implement massage techniques to enhance blood flow to organs.
  • Take a balanced diet and quit smoking.
  • Practice yoga and meditation to improve thought processes and reduce uncontrolled and involuntary movements.
  • Restlessness is related to mental health and needs medical attention if it's severe.
  • Regular practice of meditation and yoga can help calm your mind. This can reduce restlessness.
  • Prevent smoking as it can impact your calmness of body and mind.
  • Talk to your friends and family about restlessness, who can provide a solution for why you feel restless.
  • Get sufficient sleep for a minimum of 6-7 hours to reduce restlessness.
Here are the steps to cope with constipation as a side effect of medication:
  • Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
  • Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
  • Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
  • Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
  • Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
  • Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.
Here are the steps to Dry Mouth (xerostomia) caused by medication:
  • Inform your doctor about dry mouth symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Drink plenty of water throughout the day to help keep your mouth moist and alleviate dry mouth symptoms.
  • Chew sugar-free gum or candies to increase saliva production and keep your mouth moisturized.
  • Use saliva substitutes, such as mouthwashes or sprays, only if your doctor advises them to help moisturize your mouth and alleviate dry mouth symptoms.
  • Avoid consuming smoking, alcohol, spicy or acidic foods, and other irritants that may aggravate dry mouth symptoms.
  • Schedule regular dental check-ups to keep track of your oral health and handle any dry mouth issues as they arise.
Here are the step-by-step strategies to manage the side effects of " Muscle Pain" caused by medication usage:
  • Report to Your Doctor: Inform your doctor about the muscle pain, as they may need to adjust your medication.
  • Stretch Regularly: Gentle stretching can help relieve muscle pain and stiffness.
  • Stay Hydrated: Adequate water intake supports muscle health by removing harmful substances and maintaining proper muscle function.
  • Warm or Cold Compresses: Apply cold or warm compresses to the affected area to reduce pain and inflammation.
  • Rest and Relaxation: Adequate rest helps alleviate muscle strain, while relaxation techniques like deep breathing and meditation can soothe muscle tightness, calm the mind, and promote relief from discomfort.
  • Gentle Exercise: Participate in low-impact activities, such as yoga or short walks, to improve flexibility, reduce muscle tension, and alleviate discomfort.
  • Consult a physician: If your symptoms don't improve or get worse, go to the doctor for help and guidance.

Directions for Use

  • Follow your doctor’s instructions on the dosage and timing of this medication to ensure safe and effective use.
  • Stemetil Injection 10 x 1 ml will be administered by the doctor or healthcare professional.
  • Do not self-administer.

How Stemetil Injection 10 x 1 ml Works

Stemetil Injection 10 x 1 ml contains prochlorperazine, which works by targeting and blocking specific chemical receptors in the brain, primarily dopamine receptors. Dopamine is a natural chemical messenger that plays a key role in regulating mood, behaviour, and the body's nausea reflex. When dopamine levels or signals are overactive, it can trigger the vomiting centre in the brain or lead to symptoms of severe anxiety and confusion. By blocking these dopamine signals, Stemetil Injection 10 x 1 ml calms overactive nerve pathways. This dual action effectively stops the brain from sending sickness signals to the stomach while simultaneously soothing the nervous system to relieve agitation and mental distress. Because it acts directly on the central nervous system, it provides powerful and reliable symptom control.
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Alcohol

Unsafe

Avoid consumption of alcohol with Stemetil Injection 10 x 1 ml as it may increase the risk of adverse effects and cause severe breathing difficulties.

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Pregnancy

Caution

There is no information on the use of Stemetil Injection 10 x 1 ml during pregnancy. Please inform your doctor if you are pregnant before taking Stemetil Injection 10 x 1 ml . Your doctor may prescribe this medicine if the benefits outweigh the risks.

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Breast Feeding

Caution

Stemetil Injection 10 x 1 ml is not recommended to be used in breastfeeding unless absolutely necessary. Before taking this medication, discuss the risks and benefits with your doctor. Depending on your clinical condition, your doctor may prescribe a safer alternative.

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Driving

Caution

Stemetil Injection 10 x 1 ml may cause dizziness, drowsiness or blurred vision in some people. Therefore, avoid driving if you feel drowsy, dizzy or experience any vision problems after taking Stemetil Injection 10 x 1 ml .

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Liver

Caution

Take Stemetil Injection 10 x 1 ml with caution, especially if you have a history of liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Take Stemetil Injection 10 x 1 ml with caution, especially if you have a history of kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Unsafe

Stemetil Injection 10 x 1 ml is not recommended for children as safety and efficacy data are not available.

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Heart

Caution

Stemetil Injection 10 x 1 ml can affect heart rhythm and blood pressure, so it is used cautiously in heart patients. Always consult your doctor to assess risks and ensure safe administration.

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Geriatrics

Caution

Geriatric patients can receive Stemetil Injection 10 x 1 ml , but it is more sensitive to side effects like sedation, hypotension, and movement disorders. Close monitoring and dose adjustments are essential to ensure safety.

What if I have taken an overdose of Stemetil Injection 10 x 1 ml

If you suspect an overdose, seek immediate medical attention. Symptoms of an overdose can include extreme drowsiness, severe muscle stiffness, shaking, agitation, or a rapid, irregular heartbeat.

Diet & Lifestyle Advise

  • Stay hydrated: Drink small, frequent sips of water, clear broth, or electrolyte drinks to replace lost fluids and prevent dehydration from vomiting.
  • Eat bland, simple foods: When you feel ready to eat, choose low-fat, low-fibre foods like toast, crackers, bananas, or rice. Avoid spicy, greasy, or highly sweetened foods.
  • Stand up slowly: To prevent dizziness or fainting, take your time when getting up from a lying or sitting position.
  • Avoid extreme heat: This medicine can make it harder for your body to cool down. Avoid hot baths, saunas, and intense exercise in hot weather to prevent heatstroke.
  • Use sun protection: Your skin may burn more easily while using this medicine. Wear protective clothing and apply a broad-spectrum sunscreen when outdoors.
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How Soon It Starts Working

The time required for Stemetil Injection 10 x 1 ml to start to work: Stemetil Injection 10 x 1 ml ideally shows its action within 10 to 20 minutes after administration. The time for which the effects of Stemetil Injection 10 x 1 ml last: The effect of Stemetil Injection 10 x 1 ml lasts for 3 to 4 hours.

What if you forget to take Stemetil Injection 10 x 1 ml

If you miss an appointment for your injection, contact your healthcare provider right away to reschedule. If you are injecting this medicine at home and miss a dose, inject it as soon as you remember. However, if it is nearly time for your next scheduled injection, skip the missed dose and resume your regular schedule. Do not inject a double dose to make up for a missed one.

Storage

• Store Stemetil Injection 10 x 1 ml at room temperature, ideally between 20°C and 25°C (68°F to 77°F). • Keep the injection vials or ampoules in their original carton to protect them from light.

Drug Warnings

  • Check the injection solution before every use; do not inject if you see cloudiness, discolouration, or particles.
  • Always rotate your injection sites (such as switching between different areas of your thigh or arm) to prevent skin irritation, pain, or scar tissue buildup.
  • Never reuse needles or syringes, as this greatly increases the risk of serious infections.
  • Do not drive, use tools, or operate heavy machinery after receiving an injection, as this medicine can cause severe drowsiness.
  • Avoid drinking alcohol, as it can dangerously worsen drowsiness, dizziness, and breathing difficulties when combined with this medicine.
  • Be cautious in hot weather, as this medicine impairs your body's ability to sweat and regulate its temperature.

Drug-Drug Interactions

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  • Central Nervous System (CNS) Depressants: Taking Stemetil Injection 10 x 1 ml with sleeping pills, anxiety medicines, muscle relaxants, narcotic pain relievers, or other medicines that cause drowsiness can lead to excessive sleepiness, slowed breathing, dizziness, and impaired alertness. Your doctor may recommend avoiding these combinations or monitoring you closely.
  • Blood Pressure Medicines: Using Stemetil Injection 10 x 1 ml together with blood pressure-lowering medicines may cause your blood pressure to drop too low when you stand up, increasing the risk of dizziness, lightheadedness, and fainting. Your doctor may monitor your blood pressure and adjust your treatment if necessary.
  • Medicines That Affect Heart Rhythm: Certain antibiotics, antiarrhythmic medicines, and other medicines that affect heart rhythm may increase the risk of serious irregular heartbeats when taken with Stemetil Injection 10 x 1 ml . Your doctor may recommend monitoring your heart function during treatment.
ProchlorperazineMesoridazine
Critical

Drug-Drug Interactions

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How does the drug interact with Stemetil Injection 10 x 1 ml :
Coadministration of metoclopramide and Stemetil Injection 10 x 1 ml can increase the risk of side effects.

How to manage the interaction:
Taking Metoclopramide with Stemetil Injection 10 x 1 ml together is generally avoided as it can possibly result in an interaction, they can be taken together if advised by your doctor. However, if you experience muscle spasm or movements that you can't stop or control, such as lip smacking, chewing, puckering, frowning or scowling, tongue thrusting, teeth clenching, jaw twitching, blinking, eye rolling, shaking or jerking of arms and legs, tremor, jitteriness, restlessness, pacing, and foot tapping, consult the doctor. Do not stop taking any medications without consulting a doctor.
ProchlorperazineMesoridazine
Critical
How does the drug interact with Stemetil Injection 10 x 1 ml :
Coadministration of mesoridazine and Stemetil Injection 10 x 1 ml can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Taking mesoridazine with Stemetil Injection 10 x 1 ml is not recommended, but it can be taken together if prescribed by a doctor. However, contact your doctor if you experience drowsiness, lightheadedness, fainting, shortness of breath, or an irregular heartbeat. Do not stop taking any medications without consulting a doctor.
How does the drug interact with Stemetil Injection 10 x 1 ml :
Coadministration of Stemetil Injection 10 x 1 ml with ketamine can increase the risk or severity of side effects.

How to manage the interaction:
Taking Stemetil Injection 10 x 1 ml with Ketamine together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, contact your doctor if you experience dizziness, sleepiness, confusion, inability to concentrate, excessive sedation, and breathing problems. Do not stop using any medications without a doctor's advice.
How does the drug interact with Stemetil Injection 10 x 1 ml :
Taking Stemetil Injection 10 x 1 ml with Citalopram can increase the risk of irregular heart rhythm.

How to manage the interaction:
Co-administration of Stemetil Injection 10 x 1 ml with Citalopram can possibly result in an interaction, but it can be taken if your doctor has advised it. However, contact your doctor if you experience drowsiness, lightheadedness, fainting, shortness of breath, or irregular heartbeat. Do not discontinue any medications without first consulting your doctor.
How does the drug interact with Stemetil Injection 10 x 1 ml :
Co-administration of tramadol with Stemetil Injection 10 x 1 ml can increase the risk of seizures(fits).

How to manage the interaction:
Taking Stemetil Injection 10 x 1 ml and tramadol together can possibly result in an interaction; it can be taken if your doctor has advised it. However, if you experience any unusual symptoms, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Stemetil Injection 10 x 1 ml :
Using moxifloxacin together with Stemetil Injection 10 x 1 ml can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Although taking Moxifloxacin and Stemetil Injection 10 x 1 ml together can evidently cause an interaction, it can be taken if your doctor has suggested it. If you experience symptoms like an irregular heart rhythm, a heart condition, or sudden dizziness, it is important to call your doctor right away. Do not discontinue any medications without consulting your doctor.
How does the drug interact with Stemetil Injection 10 x 1 ml :
Taking Stemetil Injection 10 x 1 ml and Ziprasidone together can raise the risk of an abnormal heart rhythm.

How to manage the interaction:
There may be a possibility of interaction between Stemetil Injection 10 x 1 ml and Ziprasidone, but it can be taken if prescribed by a doctor. However, contact a doctor if you experience drowsiness, lightheadedness, fainting, shortness of breath, or irregular heartbeat. Do not stop using any medications without talking to a doctor.
How does the drug interact with Stemetil Injection 10 x 1 ml :
Taking Arsenic trioxide and Stemetil Injection 10 x 1 ml together can raise the risk of an abnormal heart rhythm that may be serious.

How to manage the interaction:
Taking Arsenic trioxide with Stemetil Injection 10 x 1 ml together can possibly result in an interaction, but it can be taken if your doctor has advised it. You should contact your doctor immediately if you experience fainting, irregular heartbeats, prolonged diarrhoea or vomiting, sudden dizziness, lightheadedness, shortness of breath, or heart palpitations. Do not stop using any medications without a doctor's advice.
How does the drug interact with Stemetil Injection 10 x 1 ml :
Taking Stemetil Injection 10 x 1 ml with Disopyramide can increase the risk of irregular heart rhythm.

How to manage the interaction:
Co-administration of Disopyramide with Stemetil Injection 10 x 1 ml can possibly result in an interaction, but it can be taken if your doctor has advised it. If you experience any symptoms like a fast or irregular heartbeat, dizziness, fainting, shortness of breath, or severe diarrhoea or vomiting, it's important to call your doctor right away. Do not stop using any medications without talking to your doctor.
How does the drug interact with Stemetil Injection 10 x 1 ml :
Taking Stemetil Injection 10 x 1 ml and Escitalopram together can raise the risk of an abnormal heart rhythm.

How to manage the interaction:
Taking Stemetil Injection 10 x 1 ml with Escitalopram together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, contact your doctor if you experience drowsiness, lightheadedness, fainting, shortness of breath, or irregular heartbeat. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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  • Alcohol: Drinking alcohol while taking Stemetil Injection 10 x 1 ml can significantly increase its sedative effects, leading to severe drowsiness, confusion, impaired coordination, and slowed breathing. It is best to avoid alcohol during treatment.
     
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[ANTIPSYCHOTICS]

FAQs

Stemetil Injection 10 x 1 ml belongs to a class of antipsychotic medications called phenothiazines used to reduce symptoms of major mental disorders such as schizophrenia, and, acute mania. It is also used as a short-term treatment for anxiety.
Stemetil Injection 10 x 1 ml contains Prochlorperazine, an antipsychotic drug that decreases the action of dopamine (a chemical messenger involved in transmitting messages between brain cells) in the brain and helps to control psychotic symptoms in Schizophrenia. Also, Stemetil Injection 10 x 1 ml works by inhibiting dopamine receptors that stimulate the vomiting centre (chemoreceptor trigger zone – CTZ) located in the brain. Thus, Stemetil Injection 10 x 1 ml prevents nausea and vomiting.
Yes, Stemetil Injection 10 x 1 ml may be used to treat vertigo (spinning sensation) caused due to ear problems such as Meniere’s syndrome (a disorder of the inner ear).
Stemetil Injection 10 x 1 ml may cause photosensitivity (extreme sensitivity to sunlight) if used in high doses. Therefore, avoiding exposure to direct sunlight while taking Stemetil Injection 10 x 1 ml is recommended.
Stemetil Injection 10 x 1 ml should be used with caution in diabetes patients as it may increase blood sugar levels. Therefore, if you are diabetic, regular monitoring of blood sugar levels is recommended while on treatment with Stemetil Injection 10 x 1 ml .
Stemetil Injection 10 x 1 ml may cause low blood pressure in some patients while standing up suddenly from a sitting or lying down position and cause symptoms such as dizziness, sweating, nausea or fainting. Therefore, to avoid such side effects, you are recommended to get up slowly after lying down or sitting.
No, you should not drive or operate machinery after receiving an injection of Stemetil Injection 10 x 1 ml . This medicine can cause significant drowsiness, blurred vision, and slower reaction times. Always wait to see how the medicine affects you first, and talk to your doctor.
This medicine is generally only used during pregnancy if your doctor decides the benefits clearly outweigh the potential risks to the baby. Using it late in pregnancy can sometimes cause temporary movement issues or withdrawal symptoms in newborns. Talk to your doctor to discuss your options.
No, you must avoid alcohol while using Stemetil Injection 10 x 1 ml . Alcohol can dangerously increase side effects like severe drowsiness, dizziness, and slowed breathing. Talk to your doctor or pharmacist if you need help avoiding alcohol.
If the liquid in the vial or syringe looks cloudy, dark yellow, or has tiny particles floating in it, do not use it. The solution should always be clear and colourless to very pale yellow. Talk to your pharmacist for a safe replacement.
This medicine works by blocking dopamine in the brain, which is a chemical that helps control muscle movements. In some cases, this can cause temporary side effects like stiffness, trembling, or restless legs. If you notice these symptoms, talk to your doctor right away.
This medicine is sometimes used for severe, uncontrollable vomiting during pregnancy (hyperemesis gravidarum), but only after other safer treatments have failed. It must be used under strict medical supervision, so talk to your doctor about the safest choice for you.
Always place used needles and syringes directly into a puncture-proof sharps disposal container immediately after use. Never throw them in your regular household trash or recycle bins, and talk to your pharmacist or local health department about safe disposal options in your area.

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Country of origin

India

Manufacturer/Marketer address

401, LSC, C-Block, Mohan Place Saraswati Vihar Delhi DL 110034 In
Other Info - STE0002
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