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compositionComposition:SOMATOSTATIN-250MCG
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Prescription Medicine
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Somatin 250 mcg Injection is used in the treatment of severe acute gastrointestinal hemorrhage (gastrointestinal bleeding) caused by gastric or duodenal ulcers, hemorrhagic gastritis (inflammation in the lining of your stomach) and esophageal varices (enlarged veins in the esophagus). It contains somatostatin, which works by inhibiting the growth hormone, thyroid stimulating hormone, insulin and glucagon secretion as well as inhibition of stomach acid secretion. This medicine may sometimes cause side effects such as diarrhea, abdominal pain, increased glucose level in blood, nausea, vomiting, flushing and injection site reaction. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Written By ,
Reviewed By Veda Maddala , M Pharmacy
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More about the Product

Composition :

SOMATOSTATIN-250MCG

Manufacturer/Marketer :

Biological E Ltd

Consume Type :

Parenteral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Somatin 250 mcg Injection

Somatin 250 mcg Injection is a specialised medicine used to treat serious conditions affecting the digestive system, such as severe bleeding from the stomach or oesophagus, pancreatic fistulas, and complications following pancreatic surgery. Somatostatin is a hormone that your body naturally produces, and this medicine works by reproducing the effects of that natural hormone. Because it is used for serious medical conditions, it is given as an injection or continuous infusion directly into a vein in a hospital under close medical supervision.

Somatin 250 mcg Injection remains in the body for only a few minutes, so it must be given as a continuous infusion to maintain its effect throughout treatment. Your healthcare team will decide how long the infusion should continue. During treatment, you may be asked to fast (avoid eating and drinking) to allow your digestive system to rest. Once you are allowed to eat again, begin with small, bland meals and gradually return to your normal diet as advised by your healthcare team.

Most people tolerate this medicine well, although mild flushing, nausea, or a slow heart rate may occur during treatment. However, tell your healthcare team immediately if you develop severe abdominal pain, difficulty breathing, extreme dizziness, or sudden changes in your blood sugar levels.

Before starting treatment, tell your doctor if you have diabetes, kidney disease, gallbladder disease, heart rhythm or conduction problems, or if you have ever had an allergic reaction to somatostatin or similar peptide medicines. Your healthcare team will decide whether this medicine is suitable for you.

This medicine may interact with medicines that affect blood sugar levels or heart rate. If you are pregnant, breastfeeding, an older adult, or have other long-term medical conditions, your doctor will carefully weigh the benefits and risks before starting treatment.

Uses of Somatin 250 mcg Injection

Your doctor may prescribe Somatin 250 mcg Injection to help manage the following conditions:

  • Severe upper gastrointestinal bleeding: Helps control severe bleeding from swollen veins in the oesophagus (oesophageal varices) or bleeding ulcers by reducing blood flow to these areas.
  • Pancreatic fistulas: Helps reduce pancreatic fluid production, allowing abnormal passages (fistulas) to heal.
  • Complications after pancreatic surgery: Helps reduce pancreatic secretions, lowering the risk of fluid leaks and other complications after surgery.

Key Benefits

When used as prescribed, Somatin 250 mcg Injection may provide the following benefits:

  • Helps control serious internal bleeding: Reduces blood flow to the digestive tract, helping stop severe bleeding more quickly.
  • Supports healing of pancreatic fistulas: Reduces the amount of digestive fluid released by the pancreas, allowing damaged tissues to recover.
  • Helps prevent complications after pancreatic surgery: Reduces pancreatic secretions that can interfere with healing.
  • Supports recovery during emergencies: Helps stabilise serious gastrointestinal conditions while other treatments are provided.

Directions for Use

  • Follow your doctor's instructions on the dosage and timing of this medication.
  • Somatin 250 mcg Injection is administered by the doctor or healthcare professional.
  • Do not self-administer.

How Somatin 250 mcg Injection Works

Somatin 250 mcg Injection contains Somatostatin. Somatostatin works by acting like the natural hormone that your body already produces. It slows the release of several hormones and digestive secretions involved in digestion. It also narrows certain blood vessels supplying the stomach and intestines. This reduces pressure in these blood vessels and helps control active bleeding from the digestive tract. At the same time, it reduces the release of digestive enzymes and pancreatic juices. This allows the pancreas and surrounding tissues to rest, reduces leakage of digestive fluids, and supports healing of pancreatic fistulas and surgical sites. Because somatostatin is removed from the body very quickly, it has a very short duration of action and therefore must be given as a continuous intravenous infusion rather than a single injection.
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Alcohol

Consult your doctor

It is not known whether it is safe to consume alcohol with Somatin 250 mcg Injection. Please consult your doctor if you have any concerns regarding this.

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Pregnancy

Consult your doctor

If you are pregnant or planning pregnancy, inform your doctor before receiving Somatin 250 mcg Injection. Your doctor may recommend this medication if the potential benefits outweigh the potential risks.

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Breast Feeding

Consult your doctor

It is not known whether Somatin 250 mcg Injection pass into breast milk. If you are breast-feeding or plan to breast-feed, please consult your doctor before receiving it.

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Driving

Consult your doctor

It is not known whether Somatin 250 mcg Injection alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.

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Liver

Consult your doctor

Please inform your doctor if you have liver impairment/liver disease before receiving Somatin 250 mcg Injection.

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Kidney

Caution

Somatin 250 mcg Injection should be used with caution in patients with kidney failure. Therefore, please inform your doctor if you have kidney impairment/kidney disease before receiving Somatin 250 mcg Injection.

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Children

Unsafe

The safety and efficacy of Somatin 250 mcg Injection in children and adolescents have not been established.

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Heart

Consult your doctor

Please inform your doctor if you have heart disease before receiving Somatin 250 mcg Injection.

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Geriatrics

Consult your doctor

Somatin 250 mcg Injection should be given to geriatrics only when prescribed by a doctor. If you have any concerns about using Somatin 250 mcg Injection for geriatrics, please consult a doctor.

What if I have taken an overdose of Somatin 250 mcg Injection

Since this medicine is administered by trained healthcare professionals, an overdose is unlikely. If too much medicine is given, your healthcare team will reduce or stop the infusion and treat any symptoms, such as changes in blood sugar, blood pressure, or heart rate.

Diet & Lifestyle Advise

  • Follow fasting instructions: Do not eat or drink until your healthcare team tells you it is safe to do so.
  • Restart eating gradually: Begin with small, bland, easy-to-digest meals when your doctor allows you to eat again.
  • Avoid alcohol: Alcohol can worsen stomach irritation and pancreatic disease.
  • Choose low-fat foods: Limiting fatty, spicy, and sugary foods may reduce stress on your digestive system during recovery.
  • Attend all follow-up appointments: Regular monitoring helps your healthcare team assess your recovery and adjust treatment if needed.
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How Soon It Starts Working

The time required for Somatin 250 mcg Injection to start to work: The exact onset time of Somatin 250 mcg Injection has not been clinically established. The time for which the effects of Somatin 250 mcg Injection last: The duration of action for Somatin 250 mcg Injection is clinically not established.

What if you forget to take Somatin 250 mcg Injection

Because this medicine is given continuously by healthcare professionals in a hospital, a missed dose is uncommon. If your infusion is interrupted for any reason, tell your nurse or doctor immediately so treatment can be restarted promptly.

Storage

•Keep the ampoules or vials in their original carton to protect them from light.
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Keep Refrigerated. Do not freeze.Prepaid payment required.

Drug Warnings

  • Check the solution before use: Healthcare professionals should ensure the solution is clear, colourless, and free from visible particles.
  • Monitoring during treatment: Your healthcare team will regularly monitor your blood sugar, heart rate, blood pressure, and, if treatment is prolonged, your thyroid function to ensure the medicine remains safe and effective.
  • Tell your doctor about heart rhythm problems: Inform your healthcare team if you have a history of slow heart rate, heart block, or other heart rhythm disorders before treatment begins.
  • Watch the infusion site: Tell your nurse if you notice pain, redness, swelling, or leakage around the intravenous infusion site.
  • Tell your doctor if you have gallstones: This medicine may affect gallbladder function and may not be suitable for some people with gallbladder disease.

Drug-Drug Interactions

verifiedApollotooltip
  • Insulin and other diabetes medicines (i.e. metformin, gliclazide, glimepiride): Somatostatin can increase or decrease blood sugar levels, so diabetes medicines may need dose adjustments.
  • Beta-blockers and other medicines that slow the heart rate (i.e. atenolol, metoprolol, diltiazem, verapamil): Taking these medicines together may increase the risk of a slow heart rate.
No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

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  • No clinically significant food interactions are known with Somatin 250 mcg Injection when used as directed. 
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[HORMONES]

FAQs

Somatin 250 mcg Injection is used in the treatment of severe acute gastrointestinal hemorrhage (gastrointestinal bleeding) caused by gastric or duodenal ulcers, hemorrhagic gastritis (inflammation in the lining of your stomach) and esophageal varices (enlarged veins in the esophagus). It is also used to manage fistulas in the intestines, bile ducts, and pancreas, as well as to alleviate excessive secretions from gastrointestinal endocrine tumors. Additionally, it is used to prevent and treat postoperative complications following pancreatic surgery, and as coadjuvant treatment in diabetic ketoacidosis.
Somatin 250 mcg Injection contains Somatostatin as an active ingredient, which works by inhibiting the growth hormone, thyroid stimulating hormone, insulin and glucagon secretion as well as inhibition of gastric acid secretion. Additionally, it regulates the digestive system's ability to absorb nutrients, move food through the gut, control blood flow, and maintain the health and growth of gastrointestinal tissues.
Somatin 250 mcg Injection should be stored at a temperature of 2ºC to 8ºC. Protect from light and moisture. Keep out of reach of children.
Yes, Somatin 250 mcg Injection can cause diarrhoea as a side effect. Avoid spicy foods and maintain a balanced diet while taking Somatin 250 mcg Injection. However, please consult a doctor if the condition worsens.
The side effects of Somatin 250 mcg Injection include diarrhea, abdominal pain, increased glucose level in blood, nausea, vomiting, flushing and injection site reaction. If any of these side effects persist or worsen, please consult your doctor.
Please inform your doctor if you are pregnant or breastfeeding before receiving Somatin 250 mcg Injection. Your doctor may recommend this medication if the potential benefits outweigh the potential risks.
Somatin 250 mcg Injection is given as a slow injection or, more commonly, as a continuous infusion into a vein by trained healthcare professionals in a hospital. Because the medicine remains in the body for only a few minutes, a continuous infusion is usually needed to maintain its effect.
Yes. This medicine can cause both high and low blood sugar levels, so your healthcare team will monitor your blood sugar regularly during treatment, especially if you have diabetes.
Yes. Many patients are asked to avoid eating and drinking during treatment to allow the stomach and pancreas to rest. Your healthcare team will tell you when it is safe to start eating again.
Mild bloating can occur, but severe or persistent abdominal pain may indicate gallbladder problems or another complication. Tell your doctor or nurse immediately.
Information on the use of this medicine during pregnancy is limited. Your doctor will prescribe it only if the expected benefits outweigh the possible risks to you and your baby.
It is not known whether this medicine passes into breast milk. Your doctor may advise you to temporarily stop breastfeeding during treatment. If appropriate, you may wish to pump and discard your breast milk during this period to help maintain your milk supply until your doctor advises that breastfeeding can be resumed safely.
Yes. Somatostatin may temporarily slow your heart rate. Your healthcare team will monitor your heart rate and blood pressure throughout treatment, especially if you already have a heart condition.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

FC/B-1 (Extn.), Mohan Co-operative Industrial Estate Mathura Road, New Delhi - 110 044
Other Info - SOM0021
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