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compositionComposition:ISONIAZID-100MG
prescription
Prescription Medicine
info
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SOLONEX DT 100MG TABLET is used to treat and prevent tuberculosis (TB). It contains isoniazid, an antibiotic that works by preventing bacteria from producing mycolic acids, an enzyme required for cell wall formation (protective coating). As a result of the disturbance in their metabolism, bacteria that lack a cell wall die and burst. Thus, it inhibits the spread of infection by acting against the bacteria Mycobacterium tuberculosis, which causes tuberculosis.

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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

ISONIAZID-100MG

Manufacturer/Marketer :

Macleods Pharmaceuticals Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About SOLONEX DT 100MG TABLET

SOLONEX DT 100MG TABLET is a prescription medicine used to treat and prevent tuberculosis (TB) in children. This antibiotic works by stopping the growth of the bacteria that cause this serious lung infection. It is a critical part of your child's treatment plan to ensure the infection is completely cleared from their body.

To get the best results, your child must take this medicine every single day at the exact same time. It is highly recommended to take this medicine on an empty stomach, either one hour before or two hours after a meal, as food can prevent the medicine from being absorbed properly. Ensuring your child eats a balanced, nutrient-rich diet can also help support their immune system during recovery.

While taking SOLONEX DT 100MG TABLET, some children may experience mild side effects like a temporary loss of appetite or a mild upset stomach. However, you must contact your doctor immediately if you notice serious symptoms like unusual tiredness, dark urine, or yellowing of the eyes and skin. These symptoms require urgent medical evaluation.

Talk to your doctor before starting this medicine if your child has a history of liver disease, kidney issues, or nerve tingling. Do not take this if your child has had a severe allergic reaction to this medication in the past or has active liver damage.

This medicine can interact with certain other prescriptions, particularly seizure medicines, and can cause reactions when combined with specific foods like aged cheeses or certain fish. Always consult your paediatrician or pharmacist about all other medicines, vitamins, or supplements your child is currently taking.

Uses of SOLONEX DT 100MG TABLET

SOLONEX DT 100MG TABLET helps treat and prevent tuberculosis (TB) by killing or stopping the growth of tuberculosis bacteria. Your doctor may prescribe it for the following conditions:

  • Active Tuberculosis: SOLONEX DT 100MG TABLET helps by killing the active bacteria causing the infection, curing the illness when used in combination with other prescribed tuberculosis medicines.
  • Latent Tuberculosis Prevention: SOLONEX DT 100MG TABLET helps prevent inactive tuberculosis bacteria already in the child's body from turning into an active, harmful infection.

Key Benefits

Using SOLONEX DT 100MG TABLET as prescribed helps treat or prevent tuberculosis (TB) in children. Here are the key benefits you can expect:

  • Treats tuberculosis effectively: Helps eliminate tuberculosis bacteria from the body when used as part of combination therapy, supporting complete recovery from active TB.
  • Helps prevent active tuberculosis: Reduces the risk of inactive tuberculosis bacteria developing into active disease in children with latent TB infection.
  • Easy for children to take: The child-friendly dispersible tablet is easy to administer, helping ensure accurate dosing and better treatment adherence.
Side effects of Solonex Dt 100mg Tablet

Directions for Use

  • SOLONEX DT 100MG TABLET should be administered at least 30 minutes before a meal or 2 hours after a meal as directed by the doctor.
  • Follow your doctor’s instructions on the dosage and timing of this medication to ensure safety.
  • Disperse the tablet in the suggested amount of water and give the mixture to your child using an oral syringe or measuring cup.
  • Do not store the mixture for later use.

How SOLONEX DT 100MG TABLET Works

SOLONEX DT 100MG TABLET contains isoniazid, an anti-tuberculosis medicine.It works by blocking the production of mycolic acid, a fatty substance that forms an essential part of the protective cell wall of Mycobacterium tuberculosis. Without enough mycolic acid, the bacteria cannot survive or multiply properly. Without a protective cell wall, the bacteria cannot grow or multiply, allowing the body's immune system to eliminate the infection more effectively. When used as prescribed, SOLONEX DT 100MG TABLET helps treat active tuberculosis and prevents latent tuberculosis infection from progressing to active disease.
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Alcohol

Not applicable

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Pregnancy

Not applicable

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Breast Feeding

Not applicable

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Driving

Not applicable

-

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Liver

Caution

If your child has liver problems, inform your doctor before using SOLONEX DT 100MG TABLET. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your child’s health condition.

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Kidney

Caution

If your child has kidney problems, inform your doctor before using SOLONEX DT 100MG TABLET. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your child’s health condition.

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Children

Safe if prescribed

Use SOLONEX DT 100MG TABLET for children as prescribed by the paediatrician.

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Heart

Consult your doctor

Please consult your doctor before giving SOLONEX DT 100MG TABLET to your child. Your doctor will prescribe SOLONEX DT 100MG TABLET if the benefits outweigh the risks.

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Geriatrics

Not applicable

SOLONEX DT 100MG TABLET is for paediatric patients only.

What if I have taken an overdose of SOLONEX DT 100MG TABLET

If you suspect your child has taken more than the prescribed amount of this medicine, seek immediate emergency medical attention.

Diet & Lifestyle Advise

  • Give Vitamin B6 (pyridoxine) supplements: This medicine can lower the levels of Vitamin B6 in your child's body, which may lead to nerve tingling. Ask your doctor about giving a daily B6 supplement to prevent this issue.
  • Avoid excessive amounts of certain foods: Foods rich in tyramine or histamine, such as aged cheeses, soy sauce, yeast extracts, tuna, and some tropical fish, may occasionally cause flushing, sweating, headache, or a rapid heartbeat while taking this medicine. These reactions are uncommon at usual doses, but it is sensible to avoid large amounts of these foods during treatment.
  • Encourage regular meals: Provide healthy, high-protein meals to help support your child's body as it fights the infection and heals.
  • Keep your child hydrated: Encourage your child to drink plenty of fluids throughout the day to support kidney and liver function.

Health Queries

I want to order Solonex DT 100 mg Tablet for my brother. I have a valid doctor's prescription. Can I place the order?

Bayyarapu Mahesh Kumar

Bayyarapu Mahesh Kumar

M Pharmacy

Solonex DT 100 mg Tablet is a prescription-only medicine subject to regulatory restrictions in India and is not available for online sale. Even with a valid doctor's prescription, it cannot be ordered online due to applicable health and regulatory requirements. You can consult your doctor, visit a licensed offline pharmacy, or go to the hospital where the prescription was issued to obtain the medicine.
health query

Have a query?

How Soon It Starts Working

The time required for SOLONEX DT 100MG TABLET to start to work: The onset time of SOLONEX DT 100MG TABLET has not been clinically established. The time for which the effects of SOLONEX DT 100MG TABLET last: The duration of SOLONEX DT 100MG TABLET’s effect is clinically not established.

What if you forget to take SOLONEX DT 100MG TABLET

If you forget to give a dose, give it as soon as you remember. However, if it is almost time for your child's next scheduled dose, skip the missed dose and continue with the regular schedule. Do not give two doses at the same time to make up for a missed one.

Storage

•Store SOLONEX DT 100MG TABLET at room temperature between 20°C and 25°C. •Keep the tablets in their original packaging with the container tightly closed to protect them from moisture and direct sunlight.

Drug Warnings

  • Check the tablets before use: Do not use the dispersible tablets if they appear damp, broken, or crumbled.
  • Complete the full course: Continue giving SOLONEX DT 100MG TABLET exactly as prescribed, even if your child feels better. Stopping treatment too early may cause the infection to return and become more difficult to treat.
  • Monitor for unusual symptoms: Watch for unusual tiredness, weakness, yellowing of the skin or eyes, dark urine, or any changes in your child's behaviour, and contact your doctor if these occur.
  • Attend follow-up appointments: Keep all scheduled medical appointments and blood tests so your doctor can monitor your child's response to treatment and liver function.
  • Check before giving other medicines: Consult your doctor or pharmacist before giving your child any over-the-counter cough, cold, or pain medicines, as they may interact with SOLONEX DT 100MG TABLET.

Drug-Drug Interactions

verifiedApollotooltip
  • Seizure medicines (such as phenytoin or carbamazepine): SOLONEX DT 100MG TABLET may increase the levels of these medicines in the blood, raising the risk of side effects. Your doctor may monitor their levels or adjust the dose if needed.
  • Blood thinners (such as warfarin): SOLONEX DT 100MG TABLET may affect how these medicines work, increasing the risk of bleeding or reducing their effectiveness. Regular monitoring may be required.
  • Sedatives (such as diazepam): Taking these medicines with SOLONEX DT 100MG TABLET may increase their effects and side effects, including excessive drowsiness.
  • Other anti-tuberculosis medicines: When used together, some tuberculosis medicines may increase the risk of liver problems. Your doctor will monitor liver function during treatment.
IsoniazidRegorafenib
Critical
IsoniazidLovastatin
Critical

Drug-Drug Interactions

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IsoniazidRegorafenib
Critical
How does the drug interact with Solonex Dt 100mg Tablet:
When Solonex Dt 100mg Tablet is taken with Regorafenib, it can increase the levels of Regorafenib leading to side effects.

How to manage the interaction:
Taking Regorafenib with Solonex Dt 100mg Tablet is not recommended, it taken can be taken if prescribed by the doctor.
IsoniazidLovastatin
Critical
How does the drug interact with Solonex Dt 100mg Tablet:
When Lovastatin is taken with Solonex Dt 100mg Tablet, can increase the risk of myopathy (muscles problems), including rhabdomyolysis (a condition that causes your muscles to break down, which leads to muscle death).

How to manage the interaction:
Taking Solonex Dt 100mg Tablet with Lovastatin is not recommended but can be taken if a doctor has prescribed it.
IsoniazidLomitapide
Critical
How does the drug interact with Solonex Dt 100mg Tablet:
When Lomitapide is taken with Solonex Dt 100mg Tablet, Solonex Dt 100mg Tablet may increase the blood levels of lomitapide which leads to side effects.

How to manage the interaction:
Taking Solonex Dt 100mg Tablet with Lomitapide is not recommended but can be taken if prescribed by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, exhaustion, nausea, vomiting, dark urine, light stools, and skin or eye yellowing, decreased hunger, consult the doctor.
IsoniazidAlfuzosin
Severe
How does the drug interact with Solonex Dt 100mg Tablet:
Co-administration of Solonex Dt 100mg Tablet will enhance the amount or action of alfuzosin when taken together.

How to manage the interaction:
Although taking Solonex Dt 100mg Tablet with Alfuzosin together can possibly result in an interaction, it can be taken if a doctor has prescribed it. Do not discontinue any medications without a doctor's advice.
IsoniazidMipomersen
Severe
How does the drug interact with Solonex Dt 100mg Tablet:
Taking Solonex Dt 100mg Tablet and Mipomersen can increase the risk and severity of side effects of liver.

How to manage the interaction:
Although taking Solonex Dt 100mg Tablet and Mipomersen together can cause an interaction, it can be taken if a doctor has suggested it. If you notice any of these symptoms -fatigue, decreased hunger, nausea, vomiting, abdominal discomfort, dark urine, pale feces, yellowing of the skin or eyes, joint pain or swelling, fever, chills, unusual bleeding or bruises, skin rash, itching, and/or skin itchiness, please contact a doctor right away. Do not stop using any medications without talking to a doctor.
IsoniazidLeflunomide
Severe
How does the drug interact with Solonex Dt 100mg Tablet:
Taking Solonex Dt 100mg Tablet with Leflunomide can increase the risk and severity of liver problems.

How to manage the interaction:
There may be a possibility of interaction between Leflunomide and Solonex Dt 100mg Tablet, it can be taken if prescribed by a doctor. If you have any of these symptoms, it's important to contact a doctor right away: fever, chills, joint pain or swelling, unusual bleeding or bruising, a skin rash, itching, exhaustion, nausea, vomiting, abdominal pain, dark urine, light stools, and/or yellowing of the skin or eyes. Do not discontinue any medications without consulting a doctor.
IsoniazidRifabutin
Severe
How does the drug interact with Solonex Dt 100mg Tablet:
Co-administration of Rifabutin with Solonex Dt 100mg Tablet can increase the risk of liver problems.

How to manage the interaction:
Although taking Rifabutin and Solonex Dt 100mg Tablet together can cause an interaction, it can be taken if a doctor has suggested it. However, if you experience any symptoms like fever, chills, joint pain or swelling, unusual bleeding or bruising, a skin rash or itching, appetite loss, nausea, vomiting, or yellowing of the skin or the whites of your eyes, consult a doctor. Do not discontinue any medications without consulting a doctor.
IsoniazidOmeprazole
Severe
How does the drug interact with Solonex Dt 100mg Tablet:
When Omeprazole is taken with Solonex Dt 100mg Tablet, it can increase the risk of side effects.

How to manage the interaction:
Co-administration of Omeprazole with Solonex Dt 100mg Tablet can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience any unusual symptoms, consult the doctor. Do not stop using any medications without talking to a doctor.
IsoniazidHalothane
Severe
How does the drug interact with Solonex Dt 100mg Tablet:
When Halothane is taken with Solonex Dt 100mg Tablet, can increase the side affects of liver.

How to manage the interaction:
Co-administration of Solonex Dt 100mg Tablet with Halothane can possibly result in an interaction, but it can be taken if a doctor has advised it. However, if you experience symptoms such as fever, chills, joint pain or swelling, unusual bleeding or bruising, a skin rash or itching, appetite loss, nausea, vomiting, or yellowing of the skin or the whites of your eyes, consult a doctor right away. Do not stop using any medications without talking to a doctor.
IsoniazidTizanidine
Severe
How does the drug interact with Solonex Dt 100mg Tablet:
Co-administration of Solonex Dt 100mg Tablet may considerably enhance the blood levels of Tizanidine, which may result in side effects.

How to manage the interaction:
There may be a possibility of interaction between Tizanidine and Solonex Dt 100mg Tablet, but it can be taken if prescribed by a doctor. However, consult a doctor if you experience excessive drowsiness, dizziness, lightheadedness, fainting, and irregular heart rhythm. Do not stop taking any medications without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip
  • Foods high in tyramine (such as aged cheese): Eating large amounts of these foods while taking SOLONEX DT 100MG TABLET may occasionally cause flushing, headache, sweating, a rapid heartbeat, or raised blood pressure. This interaction is uncommon at standard doses.
  • Foods high in histamine (such as tuna, mackerel, and other poorly stored fish): Combining these foods with SOLONEX DT 100MG TABLET may occasionally increase the risk of flushing, headache, sweating, itching, or a rapid heartbeat. Limiting large amounts of these foods during treatment may help reduce this risk.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[ANTI- TUBERCULOSIS]

FAQs

SOLONEX DT 100MG TABLET is used to treat and prevent tuberculosis (TB). SOLONEX DT 100MG TABLET is used in combination with other anti-tuberculosis agents.
SOLONEX DT 100MG TABLET contains isoniazid, an antibiotic used to treat and prevent tuberculosis. SOLONEX DT 100MG TABLET prevents bacteria from producing mycolic acids, which are required for the formation of cell walls (protective coating). Additionally, SOLONEX DT 100MG TABLET may combine with an enzyme that interferes with bacterial cell metabolism. Bacteria die as a result of the disruption in their metabolism and the lack of a cell wall. As a result, it kills Mycobacterium tuberculosis bacteria that causes tuberculosis (TB) and eliminates the infection.
You are recommended to avoid giving foods containing histamine or tyramine such as cured meat, matured cheese, soya, tuna, salmon, and mackerel to your child as they may interact with SOLONEX DT 100MG TABLET and cause adverse effects such as sweating, headache, dizziness, light-headedness, flushing (reddening of the skin), fainting due to low blood pressure, uneven, fast or forceful heartbeat.
It is best to give SOLONEX DT 100MG TABLET on an empty stomach, either 1 hour before or 2 hours after a meal, as this helps the body absorb the medicine properly. If the medicine causes an upset stomach, talk to your doctor or pharmacist.
If your child vomits shortly after taking their dose, do not give them another dose right away. Contact your paediatrician or pharmacist to get specific instructions on whether to repeat the dose.
This medicine can lower Vitamin B6 levels in the body, which can cause nerve tingling or numbness in the hands and feet. Giving a Vitamin B6 supplement helps prevent this. Talk to your doctor to see if your child needs a supplement.
Place the disintegrating tablet directly on your child's tongue and let it dissolve completely before they swallow. If needed, you can dissolve it in a small spoon of water as directed by your pharmacist.
Watch for yellowing of your child's skin or the whites of their eyes, dark urine, severe tiredness, loss of appetite, or severe stomach pain. If you notice any of these signs, stop the medicine and call your doctor right away.
Give the missed dose as soon as you remember. If it is almost time for the next scheduled dose, skip the missed one and stick to the regular schedule. Never give a double dose to make up for a missed one. Talk to your doctor if you miss multiple doses.
No. The food interaction with SOLONEX DT 100MG TABLET is uncommon at the doses usually prescribed for children. Your child does not need to avoid all cheese or fish, but it is best to avoid large amounts of aged cheeses and poorly stored fish during treatment. Talk to your doctor or dietitian if you are unsure which foods are suitable.

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Country of origin

India

Manufacturer/Marketer address

Atlanta Arcade, Marol Church Road, Andheri (East), Mumbai - 400059, INDIA.
Other Info - SOL0027
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