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  3. Sodium Nitrite 300Mg Inj 10Ml

Sodium Nitrite 300Mg Inj 10Ml, Pack of 1 Injection
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Written By ,
Reviewed By Praneetha Akunuri , M.Pharmacy

Sodium Nitrite 300Mg Inj contains sodium nitrite, which is used as an antidote for cyanide poisoning that works by neutralizing the poison and reducing its harm. You may experience common side effects like nausea, vomiting, hypotension, pain at the site of injection, tachycardia (rapid heart rate), headache, dizziness, tachypnea (fast breathing), dyspnea (shortness of breath), and fatigue (weakness). Before taking Sodium Nitrite 300Mg Inj, inform your doctor about any allergies or pre-existing medical conditions.

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Composition :

SODIUM NITRITE-300MG

Manufacturer/Marketer :

Troikaa Pharmaceuticals Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Sodium Nitrite 300Mg Inj

Sodium Nitrite 300Mg Inj is an antidote that is used to treat cyanide poisoning. Cyanide poisoning is a condition that occurs when cyanide, a toxic chemical, enters your body, preventing it from using oxygen. This can cause organ damage and be fatal.

Sodium Nitrite 300Mg Inj contains sodium nitrite, which works by converting haemoglobin into methemoglobin. Methemoglobin binds to cyanide and reduces its toxic effects, helping to protect the body from cyanide poisoning by preventing oxygen deprivation.

Sodium Nitrite 300Mg Inj will be administered by a healthcare professional; do not self-administer. Some people may experience nausea, vomiting, hypotension, pain at the site of injection, tachycardia (rapid heart rate), headache, dizziness, tachypnea (rapid breathing), dyspnea (shortness of breath), and fatigue (weakness). Most of these side effects of Sodium Nitrite 300Mg Inj do not require medical attention and gradually resolve over time. However, please contact your doctor if these side effects persist or worsen.

Before starting treatment with Sodium Nitrite 300Mg Inj, inform your doctor if you are allergic to any of its components. Consult your doctor if you are breastfeeding or pregnant. Let your doctor know if you have any pre-existing medical conditions or liver/kidney diseases before receiving Sodium Nitrite 300Mg Inj.

Uses of Sodium Nitrite 300Mg Inj

Sodium Nitrite 300Mg Inj is used in the treatment of cyanide poisoning. The detailed use of Sodium Nitrite 300Mg Inj is as follows:<br/>• Treatment of cyanide poisoning: Sodium Nitrite 300Mg Inj plays a vital role in treating acute cyanide poisoning by generating methemoglobin that binds cyanide, enabling essential bodily functions to restart and facilitating patient recovery.<br/>

Directions for Use

• Follow your doctor's instructions on the dosage and timing of this medication to ensure safe and effective use.• Sodium Nitrite 300Mg Inj should be administered by a nurse or doctor to ensure proper dosage, technique, and monitoring for any potential side effects or complications.• Do not self-administer.

Medicinal Benefits

Sodium Nitrite 300Mg Inj is an antidote for cyanide poisoning. It works by converting haemoglobin into methemoglobin, which binds to cyanide and reduces its toxic effects. It also helps protect the body from cyanide poisoning by preventing oxygen deprivation.

How Sodium Nitrite 300Mg Inj Works

Sodium Nitrite 300Mg Inj contains sodium nitrite, which works by converting haemoglobin into methemoglobin. Methemoglobin binds to cyanide and reduces its toxic effects, helping to protect the body from cyanide poisoning by preventing oxygen deprivation.

Storage

• Store in a cool and dry place away from sunlight.
• Keep Sodium Nitrite 300Mg Inj out of the sight and reach of children.
• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Sodium Nitrite 300Mg Inj 10Ml
Managing Low Blood Pressure Triggered by Medication: Expert Advice:
  • If you experience low blood pressure symptoms like dizziness, lightheadedness, or fainting while taking medication, seek immediate medical attention.
  • Make lifestyle modifications and adjust your medication regimen under medical guidance to manage low blood pressure.
  • As your doctor advises, regularly check your blood pressure at home. Record your readings to detect any changes and share them with your doctor.
  • Fluid intake plays a vital role in managing blood pressure by maintaining blood volume, regulating blood pressure, and supporting blood vessel function. Drinking enough fluids helps prevent dehydration, maintain electrolyte balance, and regulate fluid balance.
  • Take regular breaks to sit or lie down if you need to stand for long periods.
  • When lying down, elevate your head with extra pillows to help improve blood flow.
  • Avoid heavy exercise or strenuous activities that can worsen low blood pressure.
  • Wear compression socks as your doctor advises to enhance blood flow, reduce oedema, and control blood pressure.
  • If symptoms persist or worsen, or if you have concerns about your condition, seek medical attention for personalized guidance and care.
Here are the steps to manage the medication-triggered Tachycardia (Fast Heart Rate):
  • Contact your doctor immediately if you're experiencing a fast heart rate, palpitations, or other heart-related symptoms. This is crucial to determine whether the symptoms are related to your medication.
  • Your doctor may need to adjust your medication regimen to alleviate the fast heart rate symptoms. This could involve changing the medication, reducing the dosage, or adding new medications to counteract the side effects.
  • Follow your doctor's advice on monitoring your heart rate and blood pressure. This will help track any changes and ensure your heart rate returns normal.
  • If you experience severe symptoms such as chest pain, dizziness, or shortness of breath, seek immediate medical attention. These symptoms can indicate a more serious condition that requires prompt treatment.
  • Avoid triggers like alcohol, caffeine, and energy drinks.
  • Try relaxation techniques such as yoga, meditation, or deep breathing.
  • Exercise regularly as it helps maintain heart health.
  • Follow a nutritious and balanced diet.
  • If you're experiencing irregular heartbeats, palpitations, or other cardiac concerns, contact your doctor promptly. Your healthcare provider may adjust your medication regimen to alleviate symptoms.
  • Follow your doctor's instructions for monitoring heart rate and blood pressure.
  • Seek immediate medical attention if you experience severe symptoms, including chest pain, dizziness, and shortness of breath. These symptoms may indicate a more serious condition requiring prompt treatment.
  • Avoid consuming stimulants like caffeine, nicotine, and certain medications that can increase heart rate.
  • Engage in moderate exercise, such as walking or yoga, to enhance cardiovascular health and reduce stress.
  • Increase your intake of potassium-rich foods, including bananas, leafy greens, and sweet potatoes, to help regulate heart rhythm.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.

What if I have taken an overdose of Sodium Nitrite 300Mg Inj

Sodium Nitrite 300Mg Inj is administered by a health care professional in a hospital setting. Hence, the chances of overdose are less. Symptoms of overdose may include dyspnea (shortness of breath), nausea, tachycardia (rapid heart rate), and anxiety. Consult your doctor right away if you suspect any signs of an overdose.

Drug Warnings

If you are allergic to Sodium Nitrite 300Mg Inj or any other medicines, inform your doctor. Let your doctor know if you are pregnant, breastfeeding, or have liver or kidney problems. Avoid alcohol during treatment with Sodium Nitrite 300Mg Inj. Always discuss any medical conditions with your doctor before starting treatment. Follow your doctor’s advice on the proper use of Sodium Nitrite 300Mg Inj.

Drug-Drug Interactions

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Sodium nitritePrimaquine
Severe
Sodium nitriteNitrofurantoin
Severe

Drug-Drug Interactions

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Sodium nitritePrimaquine
Severe
How does the drug interact with Sodium Nitrite 300Mg Inj 10Ml 300Mg Inj 10Ml:
Co-administration of Sodium Nitrite 300Mg Inj 10Ml and Primaquine can increase the risk of methemoglobinemia(a condition in which the iron in the hemoglobin molecule -the red blood pigment is defective, making it unable to carry oxygen effectively to the tissues).

How to manage the interaction:
Although there is a possible interaction between Primaquine and Sodium Nitrite 300Mg Inj 10Ml, you can take these medicines together if prescribed by a doctor. However, if you experience symptoms such as gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, fatigue, rapid or shallow breathing, a rapid heartbeat, anxiety, consult the doctor immediately. Do not discontinue any medications without consulting a doctor.
Sodium nitriteNitrofurantoin
Severe
How does the drug interact with Sodium Nitrite 300Mg Inj 10Ml 300Mg Inj 10Ml:
Combining Nitrofurantoin with Sodium Nitrite 300Mg Inj 10Ml can increase the risk of methemoglobinemia (a condition in which the iron in the hemoglobin molecule is defective, making it unable to carry oxygen effectively to the tissues).

How to manage the interaction:
Taking Nitrofurantoin with Sodium Nitrite 300Mg Inj 10Ml together can result in an interaction, but it can be taken if your doctor has advised it. If you have any of these symptoms, it's important to contact a doctor right away if you experience gray skin color, nausea, a headache, feeling dizzy or lightheaded, being tired, having trouble breathing, having a fast or irregular heartbeat, and feeling anxious or confused. Do not discontinue any medications without consulting a doctor.
Sodium nitriteIsosorbide dinitrate
Severe
How does the drug interact with Sodium Nitrite 300Mg Inj 10Ml 300Mg Inj 10Ml:
Taking isosorbide dinitrate with Sodium Nitrite 300Mg Inj 10Ml may cause methemoglobinemia (blood disorder in which too little oxygen is delivered to your cells).

How to manage the interaction:
Although taking isosorbide dinitrate and Sodium Nitrite 300Mg Inj 10Ml together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you develop gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion. Do not stop using any medications without consulting doctor.
Sodium nitriteBenzocaine
Severe
How does the drug interact with Sodium Nitrite 300Mg Inj 10Ml 300Mg Inj 10Ml:
When Sodium Nitrite 300Mg Inj 10Ml and Benzocaine can rarely increase the risk or severity of methemoglobinemia (reduced oxygen supply in the body).

How to manage the interaction:
Although there is an interaction, Benzocaine can be taken with Sodium Nitrite 300Mg Inj 10Ml if prescribed by the doctor. However, if you experience headache, dizziness, shortness of breath, or palpitations, consult a doctor. Do not discontinue any medications without a doctor's advice.
Sodium nitriteGlyceryl trinitrate
Severe
How does the drug interact with Sodium Nitrite 300Mg Inj 10Ml 300Mg Inj 10Ml:
Coadministration of Sodium Nitrite 300Mg Inj 10Ml and glyceryl trinitrate has the potential to induce methemoglobinemia (a rare condition where red blood cells are unable to carry oxygen effectively to the tissues).

How to manage the interaction:
Although taking Sodium Nitrite 300Mg Inj 10Ml and glyceryl trinitrate together can possibly result in an interaction, it can be taken if your doctor has advised it. However, consult your doctor immediately if you experience symptoms such as grey discolouration of the skin, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion. Do not discontinue any medications without first consulting your doctor.
Sodium nitriteIsosorbide mononitrate
Severe
How does the drug interact with Sodium Nitrite 300Mg Inj 10Ml 300Mg Inj 10Ml:
Taking isosorbide mononitrate with Sodium Nitrite 300Mg Inj 10Ml may cause methemoglobinemia (blood disorder in which too little oxygen is delivered to your cells).

How to manage the interaction:
Although taking isosorbide mononitrate and Sodium Nitrite 300Mg Inj 10Ml together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you develop gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion. Do not stop using any medications without consulting doctor.
Sodium nitriteRasburicase
Severe
How does the drug interact with Sodium Nitrite 300Mg Inj 10Ml 300Mg Inj 10Ml:
Taking Rasburicase with chloroprocaine may cause methemoglobinemia (blood disorder in which too little oxygen is delivered to your cells).

How to manage the interaction:
Co-administration of Rasburicase with Sodium Nitrite 300Mg Inj 10Ml can possibly result in an interaction, but it can be taken if your doctor has advised it. However, consult the doctor immediately if you develop gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, tiredness, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion. Do not discontinue any medications without consulting a doctor.
Sodium nitriteDapsone
Severe
How does the drug interact with Sodium Nitrite 300Mg Inj 10Ml 300Mg Inj 10Ml:
Using Sodium Nitrite 300Mg Inj 10Ml together with dapsone may increase the risk of methemoglobinemia (a blood disorder in which too little oxygen is delivered to the cells).

How to manage the interaction:
Although there is a possible interaction between Dapsone and Sodium Nitrite 300Mg Inj 10Ml, you can take these medicines together if prescribed by a doctor. However, contact a doctor immediately if you experience headache, dizziness, shortness of breath, or a rapid heartbeat. Do not stop using any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat foods rich in antioxidants, like berries and greens.
  • Drink plenty of water to flush out toxins.
  • Exercise regularly to stay healthy.
  • Incorporate high-fiber foods like vegetables and fruits.
  • Limit your alcohol intake and quit smoking.

Habit Forming

No

Therapeutic Class

ANTIDOTES
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Alcohol

Caution

The interaction of alcohol with Sodium Nitrite 300Mg Inj is unknown. Please consult a doctor before consuming alcohol with Sodium Nitrite 300Mg Inj.

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Pregnancy

Caution

Sodium Nitrite 300Mg Inj is given to pregnant women only if the doctor thinks the benefits outweigh the risks.

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Breast Feeding

Consult your doctor

It is unknown whether Sodium Nitrite 300Mg Inj passes into breast milk, so consult your doctor before using it while breastfeeding.

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Driving

Caution

No data is available; it is unknown whether Sodium Nitrite 300Mg Inj affects your driving ability.

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Liver

Caution

Sodium Nitrite 300Mg Inj should be used with caution if you have a history of liver diseases/conditions. Your doctor will decide to administer Sodium Nitrite 300Mg Inj if the benefits are greater than the risks.

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Kidney

Caution

Sodium Nitrite 300Mg Inj should be used with caution if you have a history of kidney diseases or conditions. Your doctor will decide whether to administer it if the benefits outweigh the risks.

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Children

Caution

Sodium Nitrite 300Mg Inj is given to children in doses advised by a doctor based on the child’s age and weight.

Have a query?

FAQs

Sodium Nitrite 300Mg Inj is used in the treatment of cyanide poisoning.

Sodium Nitrite 300Mg Inj contains sodium nitrite, which works by converting haemoglobin into methemoglobin. Methemoglobin binds to cyanide and reduces its toxic effects, helping to protect the body from cyanide poisoning by preventing oxygen deprivation.

Sodium Nitrite 300Mg Inj may cause side effects such as nausea, vomiting, hypotension, pain at the site of injection, tachycardia (rapid heart rate), headache, dizziness, tachypnea (fast breathing), dyspnea (shortness of breath), and fatigue (weakness). Please consult your doctor if these side effects persist or worsen.

Sodium Nitrite 300Mg Inj should be stored at temperatures from 20°C to 25°C. Do not freeze. Keep it protected from light and out of reach of children. Sodium Nitrite 300Mg Inj should be disposed of after using once by following local guidelines or asking your pharmacist how to properly dispose of any unused medicine.

Sodium Nitrite 300Mg Inj is safe when used at the dose and duration advised by a doctor. Do not exceed the recommended doses.

You are recommended to take Sodium Nitrite 300Mg Inj for as long as it is advised by your doctor for effective results. Please contact your doctor if these symptoms continue for longer durations.

Country of origin

India

Manufacturer/Marketer address

Troikaa Pharmaceuticals Ltd., Registered Office: , 'Commerce House - 1', Satya Marg, Bodakdev, Ahmedabad-380 054. Gujarat, India.
Other Info - SOD0249

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Reference

  1. https://www.medicines.org.uk/emc/files/pil.7353.pdf
  2. https://www.drugs.com/pro/sodium-nitrite-injection.html#s-34084-4
  3. https://www.medsafe.govt.nz/profs/datasheet/d/dblSodiumNitriteinj.pdf

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