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compositionComposition:RIMONABANT-20MG
prescription
Prescription Medicine
info
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Slimnova Tablet is used to treat obesity and help lose weight. It contains Rimonabant, which causes weight loss by suppressing the appetite by blocking cannabinoid (CB) receptors in the hypothalamus. Thereby, it helps to reduce body weight. It is recommended not to be used in pregnant and breastfeeding women. Common side effects of this medication are psychiatric disorders (depression), insomnia (sleep disorder), nausea, vomiting, diarrhoea and fatigue (extreme tiredness).

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

RIMONABANT-20MG

Manufacturer/Marketer :

Dianova Healthcare Pvt Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Slimnova Tablet

Slimnova Tablet contains rimonabant, a medicine that was developed to help with weight management in certain adults with obesity or overweight. It was intended to be used along with a reduced-calorie diet and regular physical activity. Rimonabant was later withdrawn from many markets where it had been approved because its benefits were found not to outweigh the risk of serious psychiatric side effects, particularly depression. It was never approved in the United States. 

Slimnova Tablet was used in adults with obesity or in certain adults who were overweight and had related health risks, such as type 2 diabetes or abnormal levels of fats in the blood. It works by blocking cannabinoid type 1 (CB1) receptors, which are involved in appetite, food intake, and energy balance. This can reduce appetite and support weight loss. 

When rimonabant was marketed, it was taken regularly alongside diet and physical activity as part of a weight-management plan. Because its approval status differs by country and it has been withdrawn from many markets, ask your doctor whether Slimnova Tablet is currently approved and appropriate for you.

Side effects reported with rimonabant included nausea, dizziness, anxiety, sleep problems, and changes in mood. More importantly, treatment was associated with an increased risk of psychiatric problems, including depression and suicidal thoughts. Tell your doctor promptly if you notice new or worsening changes in your mood, thoughts, or behaviour.

Before using Slimnova Tablet , tell your doctor about your medical history, particularly any current or previous depression or other mental health problems, and all medicines you take. When rimonabant was authorised in the EU, it was not to be used in people with ongoing major depression or those taking antidepressants. Also tell your doctor if you are pregnant, planning to become pregnant, breastfeeding, are an older adult, or if the medicine is intended for a child, as special precautions may be needed.

Uses of Slimnova Tablet

Slimnova Tablet was used alongside a reduced-calorie diet and physical activity for weight management in certain adults. It has since been withdrawn from many markets where it had been approved because of psychiatric safety concerns. 

  • Obesity: It was used to support weight loss in adults with obesity.
  • Overweight with related health risks: It was used in certain adults who were overweight and also had risk factors such as type 2 diabetes or abnormal levels of fats in the blood.

Key Benefits

When it was approved, Slimnova Tablet was used as part of a weight-management plan to support weight loss and improvements in some health measures. These potential benefits must be considered alongside the psychiatric risks that led to its withdrawal from many markets. 

  • Supports weight loss: By reducing appetite and food intake, Slimnova Tablet helped some adults lose weight when used along with a reduced-calorie diet and physical activity.
  • May improve some metabolic measures: Treatment was associated with improvements in some measures related to blood sugar and blood fats in certain people.
  • Supports weight-management goals: Slimnova Tablet was designed to work alongside diet and regular physical activity as part of an overall weight-management plan.
Side effects of Slimnova Tablet
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
  • Always wear loose-fitting clothes which are suitable for your activity.
  • Include the diet containing fruits like watermelon, grapes, bananas and green leafy vegetables.
  • Drink plenty of water stay hydrated.
  • Avoid moving more and staying in hot sun.
  • Muscle cramps can be treated with regular exercise or yoga, which includes mild stretching, which helps strengthen the lower body.
  • Warm baths and gentle massage of the affected parts can help relieve cramps.
  • Avoid strenuous activity and take frequent breaks, as rest is critical.
  • Intake of nutritious food can help strengthen body and mind. A trained nutritionist can help design a balanced diet for strengthening muscles.
  • Speak to your doctor if the pain lasts an extended period. Medical help can be practical in finding a cure for cramps.

Directions for Use

  • Follow your doctor’s advise regarding the dosage and duration.
  • Lie down and tilt your head backwards. Pull your lower eyelid gently with your index finger to form a pocket. Instil the number of drops as advised by the doctor into the pocket of the lower eyelid. Close your eyes for 1-2 minutes.
  • Do not touch the container tip to the eye, eyelids, or surrounding areas, as it may cause contamination.

How Slimnova Tablet Works

Slimnova Tablet contains rimonabant. It blocks cannabinoid type 1 (CB1) receptors, which are part of the body's endocannabinoid system (a signalling system involved in appetite, food intake, and energy balance). By blocking these receptors, Slimnova Tablet can reduce appetite and food intake, which can support weight loss. However, CB1 receptors also play important roles in the brain, and blocking them can affect mood and mental health. Due to these safety concerns, rimonabant was withdrawn from many markets where it had been approved. Ask your doctor whether Slimnova Tablet is currently approved and appropriate for you.
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Alcohol

Caution

Do not consume alcohol while on treatment with Slimnova Tablet .

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Pregnancy

Caution

No adequate and well-controlled studies with Slimnova Tablet have been conducted on pregnant women. So, the use of Slimnova Tablet during pregnancy is not recommended.

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Breast Feeding

Caution

It is unknown whether this medicine is excreted in human milk. Therefore, Slimnova Tablet is not recommended for use in nursing mothers.

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Driving

Caution

Slimnova Tablet may cause fatigue (extreme tiredness); therefore, avoid driving vehicles or operating machinery until you return to normal.

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Liver

Caution

Limited information was available about using Slimnova Tablet in patients with liver disease. Inform your doctor before receiving the Slimnova Tablet if you have a history of liver diseases/conditions. Your doctor will prescribe only if the benefits outweigh the risks.

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Kidney

Caution

Limited information was available about using Slimnova Tablet in patients with kidney disease. Inform your doctor before receiving the Slimnova Tablet if you have a history of kidney diseases/conditions. Your doctor will prescribe only if the benefits outweigh the risks.

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Children

Unsafe

It is not recommended to use Slimnova Tablet in children under the age of 18 as the safety and efficacy are not established.

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Heart

Consult your doctor

Please consult your doctor if you have any pre-existing heart disease before using Slimnova Tablet .

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Geriatrics

Consult your doctor

Please consult a doctor if you have any concerns regarding the use of Slimnova Tablet in elderly patients.

What if I have taken an overdose of Slimnova Tablet

If you take more Slimnova Tablet than prescribed, seek medical advice promptly, even if you feel well. Take the medicine packaging with you so healthcare professionals know what you have taken. If you develop severe symptoms, such as fainting, confusion, marked changes in mood or behaviour, or difficulty breathing, seek emergency medical care.

Diet & Lifestyle Advise

  • Follow a balanced eating plan: Follow the reduced-calorie or other eating plan recommended by your doctor or dietitian rather than making extreme changes to your diet.
  • Stay physically active: Regular physical activity can support weight management and overall health. Choose activities suitable for your health and fitness level.
  • Set realistic goals: Gradual, sustainable changes in eating habits and physical activity are generally easier to maintain over time.
  • Limit alcohol: Alcohol adds calories and can affect mood and judgement. Ask your doctor whether alcohol is appropriate for you, particularly if you have mental health concerns or take other medicines.
health query

Have a query?

How Soon It Starts Working

The time required for Slimnova Tablet to start to work: The exact onset time of Slimnova Tablet has not been clinically established. The time for which the effects of Slimnova Tablet last: The duration of Slimnova Tablet effect is unknown.

What if you forget to take Slimnova Tablet

If you miss a dose of Slimnova Tablet , follow the instructions given by your doctor or pharmacist. Do not take a double dose to make up for a missed dose. If you are unsure what to do, ask your doctor or pharmacist before taking another dose.

Storage

• Store Slimnova Tablet at room temperature, preferably between 20°C and 25°C, or according to the storage instructions on the product label.

Drug Warnings

  • Be aware of mood changes: Tell your doctor promptly if you develop new or worsening depression, anxiety, or unusual changes in your mood or behaviour.
  • Seek help for thoughts of self-harm: Consult your doctor right away if you develop thoughts of harming yourself or suicide while taking Slimnova Tablet .
  • Share your mental health history: Tell your doctor if you have or have previously had depression or another mental health condition before starting treatment.
  • Tell your doctor about other medicines: Share a complete list of prescription medicines, over-the-counter medicines, vitamins, and herbal products so your doctor can check for possible interactions.
  • Discuss pregnancy and breastfeeding: Tell your doctor if you are pregnant, planning to become pregnant, or breastfeeding. Rimonabant is not recommended during pregnancy, and breastfeeding should be avoided during treatment.
  • Use in children and older adults: Rimonabant is not intended for use in children. If you are an older adult, your doctor will consider whether treatment is appropriate based on your overall health and other medicines you take.

Drug-Drug Interactions

verifiedApollotooltip
  • Strong CYP3A4 inhibitors (e.g. ketoconazole, itraconazole, ritonavir, clarithromycin, or nefazodone): These medicines can slow the breakdown of rimonabant and increase its levels in the body, which may increase the risk of side effects. Your doctor will consider whether they are appropriate to use together.
  • Strong CYP3A4 inducers (e.g. rifampicin, phenytoin, phenobarbital, or carbamazepine): These medicines can speed up the breakdown of rimonabant and may reduce its effect. Tell your doctor if you take any of these medicines.
  • Antidepressants: Rimonabant should not be used in people receiving antidepressant treatment under the prescribing restrictions that applied when it was marketed. Tell your doctor about any medicine you take for depression, anxiety, or another mental health condition.
No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

verifiedApollotooltip
  • Alcohol: Alcohol may affect mood, alertness, and judgement. Because rimonabant can also cause psychiatric or nervous-system effects, ask your doctor whether you should avoid alcohol during treatment. 
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[ANTIOBESITY DRUG]

FAQs

Slimnova Tablet contains Rimonabant, an anti-obesity drug that causes weight loss by weight loss by suppressing the appetite by blocking cannabinoid (CB) receptors in the hypothalamus. Slimnova Tablet should be used along with a low-calorie diet and regular physical exercise. Thus, Slimnova Tablet promotes weight loss and lowers the possibility of developing major health issues.
If you take too much medication, such as Rimonabant, call your doctor or go to the hospital right away.
Slimnova Tablet is contraindicated in patients with major eating disorders (anorexia nervosa or bulimia nervosa).
Rimonabant was developed to support weight loss in certain adults with obesity or overweight with related health risks. It was used alongside a reduced-calorie diet and physical activity. It has since been withdrawn from many markets where it had been approved because of psychiatric safety concerns.
Rimonabant was linked to an increased risk of psychiatric side effects, particularly depression. There were also concerns about suicidal thoughts and behaviour. Regulators concluded that its benefits did not outweigh these risks.
Yes. Rimonabant blocks CB1 receptors, which are involved in appetite and food intake. Blocking these receptors can reduce appetite and help some people eat less.
Rimonabant can cause or worsen depression and other psychiatric symptoms. When it was marketed, it was not to be used in people with ongoing major depression or those taking antidepressants. Tell your doctor about any current or previous mental health condition before treatment.
Alcohol can affect mood, alertness, and judgement. Ask your doctor whether you should avoid alcohol while taking Slimnova Tablet , particularly if you have mental health concerns or take medicines that affect the brain.
Rimonabant is not recommended during pregnancy. Tell your doctor if you are pregnant, think you may be pregnant, or are planning a pregnancy.
Breastfeeding is not recommended during treatment with rimonabant because it is not known whether the medicine passes into human breast milk and there may be a risk to the baby.
Rimonabant has been withdrawn from many markets where it had been approved because of safety concerns. Its regulatory status can vary by country, so ask your doctor whether it is currently approved and appropriate for you.
If you previously used rimonabant, do not restart treatment on your own. It was withdrawn from many markets because of concerns about serious psychiatric side effects. Speak with your doctor about your current weight-management needs and whether a currently approved treatment may be suitable for you.
Yes. Depending on your health needs and what is approved in your country, treatment options may include medicines such as orlistat or certain GLP-1 receptor agonists, including semaglutide and liraglutide. These medicines work differently and are not direct substitutes for rimonabant. Your doctor can help determine whether medication is needed and which option is appropriate for you.
Rimonabant was studied in a group of clinical trials known as the RIO (Rimonabant In Obesity) programme. These studies found that rimonabant, when used with diet and lifestyle changes, helped some adults lose weight and improve certain measures related to blood sugar and blood fats. Later evidence raised concerns about psychiatric side effects, which changed the overall assessment of its benefits and risks and led to its withdrawal from many markets.
When rimonabant was marketed for weight management, 20 mg once daily was the standard approved adult dose in regions where it was authorised. This is historical information and should not be used to start or restart treatment. Rimonabant has been withdrawn from many markets, so ask your doctor about currently approved and appropriate weight-management options.

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Country of origin

India

Manufacturer/Marketer address

H No.8-149/5TH-2,Prince View,Jetty Road, opposite State Bank, Nani Daman Daman Daman DD 396210 IN
Other Info - SLI0075

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