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  3. Skizoril MD 25 Tablets 10's

Skizoril MD 25 Tablets 10's, Pack of 10 TABLETS
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Written By ,
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy

Skizoril MD 25 Tablets is used to treat schizophrenia. Additionally, it is also used to reduce the risk of suicidal behaviour in patients with schizophrenia or other similar disorders. It contains Clozapine, which helps improve mood, behaviour, and thoughts. It may cause side effects such as tachycardia (rapid heartbeat), dizziness, headache, tremors, sweating, dry mouth, nausea, constipation, and visual disturbances. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Composition :

CLOZAPINE-25MG

Manufacturer/Marketer :

Intas Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Skizoril MD 25 Tablets

Skizoril MD 25 Tablets is used to treat schizophrenia. Additionally, Skizoril MD 25 Tablets is also used to reduce the risk of suicidal behaviour in patients with schizophrenia or other similar disorders. Schizophrenia is a medical condition in which the person may feel, hear, or see things that are not there, believe things that are not true, or feel unusually suspicious or confused.

Skizoril MD 25 Tablets contains Clozapine, which works by blocking the effects of chemical receptors in the brain, such as dopamine and serotonin. Thus, it helps in improving mood, behaviour, and thoughts.

Depending on your medical condition, you are advised to take Skizoril MD 25 Tablets for as long as your doctor has prescribed it for you. In some cases, Skizoril MD 25 Tablets may cause side effects, including tachycardia (a fast heartbeat), dizziness, headache, tremors, sweating, dry mouth, nausea, constipation, and visual disturbances. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Please do not stop taking Skizoril MD 25 Tablets suddenly, as it might cause withdrawal symptoms. Consult your doctor if you are pregnant. Do not take Skizoril MD 25 Tablets if you are breastfeeding, as it may pass into breastmilk. Avoid driving as Skizoril MD 25 Tablets may cause drowsiness and dizziness. Skizoril MD 25 Tablets should not be given to children as safety and effectiveness have not been established. Avoid consuming alcohol with Skizoril MD 25 Tablets as it could lead to increased drowsiness and dizziness. Keep your doctor informed about your health condition and any medications you are taking to help rule out any potential side effects.

Uses of Skizoril MD 25 Tablets

Skizoril MD 25 Tablets is used in the treatment of schizophrenia. The detailed uses of Skizoril MD 25 Tablets are as follows:

  • It is used in patients with schizophrenia when other antipsychotic medications have been ineffective or have caused serious side effects.
  • It is also used to reduce the risk of suicidal behaviour in patients with schizophrenia or other similar mental health conditions.
  • It is used in the management of psychotic disorders in people with Parkinson's disease when standard treatments have failed.

Directions for Use

  • Skizoril MD 25 Tablets can be taken with or without food.
  • It is usually taken 1-2 times daily at the same time each day or as prescribed by your doctor.
  • Place the tablet on your tongue and let it dissolve before swallowing.
  • Do not swallow the tablet as a whole.
  • Ensure your hands are dry before handling Skizoril MD 25 Tablets .

Medicinal Benefits

Skizoril MD 25 Tablets belongs to a group of medicines called antipsychotics. Skizoril MD 25 Tablets is used to treat schizophrenia and to reduce the risk of suicidal behaviour in patients with schizophrenia or other similar disorders. Skizoril MD 25 Tablets works by blocking the effects of chemical receptors in the brain, such as dopamine and serotonin, thereby helping in improving mood, behaviour, and thoughts. Skizoril MD 25 Tablets is used to treat schizophrenia when other antipsychotic drugs are ineffective or have caused severe adverse effects. Skizoril MD 25 Tablets is also used to treat psychotic disorders in patients with Parkinson’s disease when standard treatments have failed.

How Skizoril MD 25 Tablets Works

Skizoril MD 25 Tablets contains Clozapine, which works by blocking the effects of chemical receptors in the brain, such as dopamine and serotonin. Thus, it helps in improving mood, behaviour, and thoughts.

Storage

• Store in a cool and dry place away from sunlight.• Keep Skizoril MD 25 Tablets out of reach and sight of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Skizoril MD 25 Tablets
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Avoid driving or operating machinery or activities that require high focus until you know how the medication affects you.
  • Maintain a fixed sleeping schedule, create a relaxing bedtime routine and ensure your sleeping space is comfortable to maximize your sleep quality.
  • Limit alcohol and caffeine as these may worsen drowsiness and disturb sleep patterns.
  • Drink plenty of water as it helps with alertness and keeps you hydrated and for overall well-being.
  • Moderate physical activity can improve energy levels, but avoid intense workouts right before bedtime.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
Here are the steps to manage the medication-triggered Tachycardia (Fast Heart Rate):
  • Contact your doctor immediately if you're experiencing a fast heart rate, palpitations, or other heart-related symptoms. This is crucial to determine whether the symptoms are related to your medication.
  • Your doctor may need to adjust your medication regimen to alleviate the fast heart rate symptoms. This could involve changing the medication, reducing the dosage, or adding new medications to counteract the side effects.
  • Follow your doctor's advice on monitoring your heart rate and blood pressure. This will help track any changes and ensure your heart rate returns normal.
  • If you experience severe symptoms such as chest pain, dizziness, or shortness of breath, seek immediate medical attention. These symptoms can indicate a more serious condition that requires prompt treatment.
Managing Low Blood Pressure Triggered by Medication: Expert Advice:
  • If you experience low blood pressure symptoms like dizziness, lightheadedness, or fainting while taking medication, seek immediate medical attention.
  • Make lifestyle modifications and adjust your medication regimen under medical guidance to manage low blood pressure.
  • As your doctor advises, regularly check your blood pressure at home. Record your readings to detect any changes and share them with your doctor.
  • Fluid intake plays a vital role in managing blood pressure by maintaining blood volume, regulating blood pressure, and supporting blood vessel function. Drinking enough fluids helps prevent dehydration, maintain electrolyte balance, and regulate fluid balance.
  • Take regular breaks to sit or lie down if you need to stand for long periods.
  • When lying down, elevate your head with extra pillows to help improve blood flow.
  • Avoid heavy exercise or strenuous activities that can worsen low blood pressure.
  • Wear compression socks as your doctor advises to enhance blood flow, reduce oedema, and control blood pressure.
  • If symptoms persist or worsen, or if you have concerns about your condition, seek medical attention for personalized guidance and care.
  • Regularly brush your tongue and teeth to prevent Excessive Saliva Production.
  • Avoid eating foods high in sugar or acid since these foods might increase saliva production, which increases the Excessive Saliva Production.
  • Keep your head up straight and maintain proper posture to prevent saliva from collecting in your mouth.
Here are the steps to cope with constipation as a side effect of medication:
  • Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
  • Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
  • Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
  • Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
  • Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
  • Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.

What if I have taken an overdose of Skizoril MD 25 Tablets

Please do not take more than the prescribed dose of Skizoril MD 25 Tablets as it may cause an overdose. The symptoms of overdose include sedation, fast heart rate, high blood pressure, respiratory depression or failure, delirium (profound changes in mental abilities), coma or excess saliva production. If you suspect you have taken an overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

Do not take Skizoril MD 25 Tablets if you are allergic to any of its contents if you have galactose intolerance, total lactase deficiency, glucose-galactose malabsorption, low number of white blood cells or if you are taking medicines that can cause low levels of white blood cells, bone marrow disorder, epilepsy, circulatory collapse (pronounced fall in blood pressure that can lead to unconsciousness), brain disorders, severe kidney disease, heart disease, liver disease with jaundice, liver failure or paralytic ileus (small intestine disorder). Inform your doctor if you have a low number of white blood cells or platelet count, orthostatic hypotension, epilepsy, enlarged prostate or difficulty urinating, glaucoma, severe constipation, diabetes, heart, liver, or kidney problems. Consult your doctor if you are pregnant. Do not take Skizoril MD 25 Tablets if you are breastfeeding, as it may pass into breastmilk.

Drug-Drug Interactions

verifiedApollotooltip
ClozapineCisapride
Critical
ClozapinePimozide
Critical

Drug-Drug Interactions

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ClozapineCisapride
Critical
How does the drug interact with Skizoril MD 25 Tablets:
When Skizoril MD 25 Tablets is taken with Cisapride, can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Taking Skizoril MD 25 Tablets with Cisapride there may be a possibility of interaction, but it can be taken if prescribed by a doctor. Call a doctor immediately if you notice any of these signs - like sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medications without a doctor's advice.
ClozapinePimozide
Critical
How does the drug interact with Skizoril MD 25 Tablets:
When Skizoril MD 25 Tablets is taken with Pimozide, can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Taking Skizoril MD 25 Tablets with Pimozide there may be a possibility of interaction, but it can be taken if prescribed by a doctor. Call a doctor immediately if you notice any of these signs - like sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medications without a doctor's advice.
ClozapineRopinirole
Critical
How does the drug interact with Skizoril MD 25 Tablets:
When Ropinirole is taken with Skizoril MD 25 Tablets, it may not work as well.

How to manage the interaction:
Taking Ropinirole with Skizoril MD 25 Tablets is not recommended as it can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as drowsiness, low blood pressure, dizziness, and lightheadedness. Do not stop using any medications without consulting doctor.
ClozapineFlibanserin
Critical
How does the drug interact with Skizoril MD 25 Tablets:
When Flibanserin and Skizoril MD 25 Tablets are taken together, may increase side effects.

How to manage the interaction:
There may be a possibility of interaction between Skizoril MD 25 Tablets and Flibanserin, but it can be taken if prescribed by a doctor. If you notice any of these signs - like dizziness, drowsiness, fatigue, and difficulty concentrating, call a doctor right away. Do not stop using any medications without a doctor's advice.
ClozapineSparfloxacin
Critical
How does the drug interact with Skizoril MD 25 Tablets:
When Skizoril MD 25 Tablets is taken with Sparfloxacin, can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Taking Skizoril MD 25 Tablets with Sparfloxacin there may be a possibility of interaction, but it can be taken if prescribed by a doctor. Call a doctor immediately if you notice any of these signs - like sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medications without a doctor's advice.
ClozapinePotassium citrate
Critical
How does the drug interact with Skizoril MD 25 Tablets:
Taking Skizoril MD 25 Tablets and Potassium citrate (in tablet or capsule form) together can increase the risk of stomach ulcers, bleeding, and other gastrointestinal injury.

How to manage the interaction:
Co-administration of Potassium citrate with Skizoril MD 25 Tablets is not recommended, as it may lead to an interaction, it can be taken if prescribed by the doctor. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, or dark, tarry stools, consult the doctor immediately. Do not discontinue any medications without a doctor's advice.
ClozapineMetoclopramide
Critical
How does the drug interact with Skizoril MD 25 Tablets:
Co-administration of Metoclopramide with Skizoril MD 25 Tablets can increase the risk of side effects.

How to manage the interaction:
Taking Metoclopramide with Skizoril MD 25 Tablets is generally avoided as it can possibly result in an interaction, it can be taken if your doctor has advised it. Do not discontinue any medications without consulting a doctor.
ClozapineKetamine
Severe
How does the drug interact with Skizoril MD 25 Tablets:
When Skizoril MD 25 Tablets is taken with Ketamine, may increase side effects.

How to manage the interaction:
Co-administration of Ketamine with Skizoril MD 25 Tablets can possibly result in an interaction, but it can be taken if a doctor has advised it. If you feel dizzy, sleepy, confused, have trouble focusing, feel too relaxed, or have trouble breathing, make sure to contact a doctor right away. Do not stop using any medications without a doctor's advice.
ClozapineCyclophosphamide
Severe
How does the drug interact with Skizoril MD 25 Tablets:
Taking Skizoril MD 25 Tablets and Cyclophosphamide may increase the risk of infection.

How to manage the interaction:
Taking Cyclophosphamide with Skizoril MD 25 Tablets can possibly lead to an interaction. However, they can be taken together if prescribed by the doctor. Consult the doctor if you experience signs and symptoms of infection such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not discontinue the medication without consulting a doctor.
ClozapineColchicine
Severe
How does the drug interact with Skizoril MD 25 Tablets:
Taking Colchicine and Skizoril MD 25 Tablets can increase the risk of infections.

How to manage the interaction:
Although taking Colchicine and Skizoril MD 25 Tablets together may possibly result in an interaction, they can be taken together if prescribed by your doctor. However, contact your doctor immediately if you experience fever, sore throat, muscle pain, chills, or burning during urination. Do not discontinue any medication without consulting your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Maintain a healthy diet and exercise regularly.
  • Include fruits, vegetables, and fibre-rich food in your diet.
  • Cut down on sugars, salts, and saturated fats.
  • Drink enough fluids to stay hydrated.
  • Regularly attend therapy sessions.
  • Perform meditation and yoga.
  • Follow a regular sleep pattern.
  • Avoid smoking and alcohol consumption.
  • Learn about your condition, understand the risk factors, and follow the doctor’s treatment plan.

Habit Forming

No

Therapeutic Class

PSYCHOTHERAPEUTICS

Skizoril MD 25 Tablets Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Unsafe

Avoid consumption of alcohol while taking Skizoril MD 25 Tablets as it may cause increased drowsiness.

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Pregnancy

Caution

Skizoril MD 25 Tablets belongs to pregnancy category B. Please consult your doctor if you are pregnant before taking this medicine; your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

Skizoril MD 25 Tablets is not recommended for use during breastfeeding.

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Driving

Unsafe

Skizoril MD 25 Tablets causes tiredness, dizziness and vision problems. Do not drive or operate machinery if you experience these symptoms.

bannner image

Liver

Consult your doctor

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have liver problems or any concerns regarding this.

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Kidney

Consult your doctor

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney problems or any concerns regarding this.

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Children

Unsafe

Skizoril MD 25 Tablets should not be given to children as safety and effectiveness have not been established.

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Heart

Skizoril MD 25 Tablets is contraindicated in patients with heart problems, as it may cause changes in heart rhythm, including a condition called QT prolongation. Therefore, please consult your doctor before using Skizoril MD 25 Tablets .

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Geriatrics

Consult your doctor

Use Skizoril MD 25 Tablets only under doctor's guidance due to increased risk of side effects. Consult your doctor for personalized advice.

Have a query?

FAQs

Skizoril MD 25 Tablets is used to treat schizophrenia. Additionally, it is also used to reduce the risk of suicidal behaviour in patients with schizophrenia or other similar disorders.

Skizoril MD 25 Tablets works by blocking the effects of chemical receptors in the brain, such as dopamine and serotonin, thereby improving mood, behaviour, and thoughts.

Do not discontinue Skizoril MD 25 Tablets without consulting your doctor, as it could cause withdrawal symptoms. To treat your condition effectually, continue taking Skizoril MD 25 Tablets for as long as prescribed. Do not hesitate to consult your doctor if you experience any difficulties while taking Skizoril MD 25 Tablets .

Skizoril MD 25 Tablets may cause agranulocytosis (low levels of white blood cells), making you more prone to infections. Consult your doctor immediately if you experience flu-like symptoms, sore throat or fever.

Dry mouth may be a side effect of Skizoril MD 25 Tablets . Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly, and chewing sugar-free gum or candy may stimulate saliva and prevent mouth dryness.

Orthostatic hypotension, a sudden lowering of blood pressure that causes dizziness when standing, could be a side effect of Skizoril MD 25 Tablets . If you experience this, do not try to stand up suddenly or start walking; instead, lie down and get up slowly only when you feel better.

Skizoril MD 25 Tablets may cause tachycardia (fast heartbeat). Talk to your doctor if you experience irregular or rapid heartbeat even at rest, chest pain, unexplained tiredness or breathing problems.

If you forget a dose of Skizoril MD 25 Tablets , take it as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and take your regular dose. Do not take a double dose to make up for the missed one.

Country of origin

India

Manufacturer/Marketer address

Corporate House, Near Sola Bridge, S. G. Highway, Thaltej, Ahmedabad – 380054. Gujarat. India
Other Info - SKI0265

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Reference

  1. https://www.accessdata.fda.gov/drugsatfda_docs/label/2015/203039Orig1s000lbl.pdf
  2. https://dailymed.nlm.nih.gov/dailymed/getFile.cfm?setid=9ae4b8e4-d8b1-4f01-bb4c-cd1cea90b219&type=pdf
  3. https://www.drugs.com/clozapine.html
  4. https://medlineplus.gov/druginfo/meds/a691001.html

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