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  3. Siz-LS Capsule 10's

Siz-LS Capsule 10's, Pack of 10
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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Siz-LS Capsule is used to treat gastro-oesophageal reflux disease (GERD), acidity, heartburn, Zollinger-Ellison syndrome, Helicobacter pylori infection, irritable bowel syndrome, indigestion, duodenal and gastric ulcers. It contains Rabeprazole and Levosulpiride which work by blocking acid production and preventing the backflow of food and acid into the mouth. In some cases, this medicine may cause side effects such as headache, nausea, vomiting, gas, abdominal pain, dizziness, and diarrhoea. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Composition :

LEVOSULPIRIDE-75MG + RABEPRAZOLE-20MG

Manufacturer/Marketer :

Zentis Drugs Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Siz-LS Capsule

Siz-LS Capsule is used to treat gastro-oesophageal reflux disease (GERD), acidity, heartburn, Zollinger-Ellison syndrome, Helicobacter pylori infection, irritable bowel syndrome, indigestion, duodenal and gastric ulcers. The stomach is usually protected from acid by a mucous layer. In some cases, due to excess acid production, the mucous layer gets eroded, which leads to acidity. 
 
Siz-LS Capsule is a combination of two drugs: Rabeprazole (proton pump inhibitor) and Levosulpiride (prokinetic agent). Rabeprazole works by blocking an enzyme called the gastric proton pump, which is responsible for acid production. Levosulpiride works by increasing the pressure of the inferior oesophageal (food pipe) sphincter, thereby preventing the backflow of food and acid into the mouth. Together, Siz-LS Capsule helps in preventing acid reflux, thereby providing relief from acidity and heartburn.
 
You are advised to take Siz-LS Capsule for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side effects, such as headache, nausea, vomiting, gas, abdominal pain, dizziness, and diarrhoea. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
 
Inform your doctor if you have a history of gastrointestinal bleeding or intestinal obstruction. On long-term treatment, Siz-LS Capsule may cause osteoporosis and hypomagnesemia. Consult a doctor if you are pregnant or breastfeeding. Siz-LS Capsule may cause drowsiness and dizziness, so drive only if you are alert. Siz-LS Capsule is not recommended for children as safety and effectiveness have not been established. Avoid consuming alcohol along with Siz-LS Capsule as it could lead to increased drowsiness and elevate stomach acid production.

Uses of Siz-LS Capsule

Treatment of Gastro-oesophageal reflux disease, acidity, indigestion, heartburn, and peptic ulcers.

Directions for Use

• Siz-LS Capsule should be taken 1 hour prior to food, or as advised by the doctor.• Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.• Swallow Siz-LS Capsule as a whole with a glass of water.• Do not chew, crush or break it.

Medicinal Benefits

Siz-LS Capsule is a combination of two drugs: Rabeprazole and Levosulpiride. Siz-LS Capsule belongs to a group of medicines called gastrointestinal agents used to treat gastro-oesophageal reflux disease (GERD), acidity, heartburn, Zollinger-Ellison syndrome, Helicobacter pylori infection, irritable bowel syndrome, indigestion, duodenal and gastric ulcers. Rabeprazole is a proton pump inhibitor that works by blocking an enzyme called gastric proton pump, which is responsible for the production of acid. Levosulpiride is a prokinetic agent that increases the pressure of the inferior oesophageal (food pipe) sphincter, thereby preventing the backflow of food and acid into the mouth. Together, Siz-LS Capsule helps in preventing acid reflux, thereby providing relief from acidity and heartburn. 

How Siz-LS Capsule Works

Siz-LS Capsule is a combination of two drugs: Rabeprazole (proton pump inhibitor) and Levosulpiride (prokinetic agent). Rabeprazole works by blocking an enzyme called the gastric proton pump, which is responsible for acid production. Levosulpiride works by increasing the pressure of the inferior oesophageal (food pipe) sphincter, thereby preventing the backflow of food and acid into the mouth. Together, Siz-LS Capsule helps in preventing acid reflux, thereby providing relief from acidity and heartburn.

Storage

Keep Siz-LS Capsule out of reach and sight of children.

What if I have taken an overdose of Siz-LS Capsule

Take Siz-LS Capsule only as prescribed by the physician. Do not exceed the recommended dose, as it might cause an overdose. If you suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

Do not take Siz-LS Capsule if you are allergic to any of its components. Inform your doctor if you have a history of pheochromocytoma (tumour of the adrenal gland), epilepsy, mania, gastrointestinal bleeding, intestinal obstruction, or severe kidney or liver impairment. Siz-LS Capsule may cause osteoporosis (weak and brittle bones) and hypomagnesemia (low magnesium levels) on long-term treatment. Consult a doctor if you are pregnant or breastfeeding. Siz-LS Capsule may cause dizziness and drowsiness, so drive only if you are alert. Siz-LS Capsule is not recommended for children as safety and effectiveness have not been established.

Diet & Lifestyle Advise

  • Eat smaller meals more often.

  • Avoid smoking and alcohol consumption. Alcohol intake leads to increased production of stomach acid, thereby increases acidity and heartburn.

  • Maintain a healthy weight by regular exercising.

  • Avoid lying down after eating to prevent acid reflux.

  • Avoid tight-fitting clothes as it might increase the pressure on the abdomen leading to acid reflux.

  • Practice relaxation techniques and avoid stress by doing yoga or meditation.

  • Avoid foods such as high-fat food, spicy food, chocolates, citrus fruits, pineapple, tomato, onion, garlic, tea, and soda. 

  • Avoid sitting continuously as it may trigger acidity. Take a break of 5 minutes every hour by doing brisk walking or stretching.

Habit Forming

No

Therapeutic Class

ANTACIDS, ANTIULCERANTS

Siz-LS Capsule Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Unsafe

Avoid consumption of alcohol while taking Siz-LS Capsule . Alcohol intake leads to increased production of stomach acid, thereby increases acidity and heartburn.

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Pregnancy

Caution

Consult your doctor if you are pregnant; your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

Siz-LS Capsule may pass into breast milk. Consult your doctor if you are breastfeeding; your doctor will decide whether Siz-LS Capsule can be taken by breastfeeding mothers or not.

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Driving

Caution

Siz-LS Capsule may cause dizziness and drowsiness. Do not drive or operate machinery unless you are alert.

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Liver

Caution

Dose adjustment may be needed. Consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed. Consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Unsafe

Siz-LS Capsule should not be given to children as the safety and effectiveness were not established.

Have a query?

FAQs

Siz-LS Capsule is used to treat gastro-oesophageal reflux disease (GERD), acidity, heartburn, Zollinger-Ellison syndrome, Helicobacter pylori infection, irritable bowel syndrome, indigestion, duodenal and gastric ulcers.

Siz-LS Capsule contains Rabeprazole and Levosulpiride. Rabeprazole works by blocking an enzyme called gastric proton pump, which is responsible for the production of acid. Levosulpiride works by increasing the pressure of the inferior oesophageal (food pipe) sphincter, thereby prevents the backflow of food and acid into the mouth. Together, Siz-LS Capsule helps in providing relief from acidity.

Avoid lying down immediately after meals to prevent acid reflux. Raise the head of the bed 10-20cm by putting on a pillow so that the head and chest are above the waist. This helps in preventing acid reflux.

Siz-LS Capsule contains rabeprazole which might increase the risk of osteoporosis (weak and brittle bones). This mainly occurs in people taking higher doses of Siz-LS Capsule for longer durations. Inform your doctor if you are at risk of osteoporosis. Your doctor may prescribe calcium and vitamin D supplements.

Dry mouth could be a side-effect of Siz-LS Capsule . Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly, and chewing sugar-free gum/candy might help stimulate saliva and thereby prevent drying of the mouth.

Do not take Siz-LS Capsule for longer durations unless prescribed by the doctor. Siz-LS Capsule might cause bone problems and hypomagnesemia on long-term treatment. Talk to your doctor if you do not find symptomatic relief despite taking Siz-LS Capsule for 2 weeks.

Siz-LS Capsule might cause irregular periods/abnormal menstruation. Consult your doctor if you notice abnormal bleeding patterns.

Avoid consuming alcohol along with Siz-LS Capsule as it could lead to increased drowsiness and elevate stomach acid production.

If you're experiencing frequent heartburn and stomach pain while taking Siz-LS Capsule , it's essential to consult with your doctor. They can assess your specific situation and provide the best course of action.

Siz-LS Capsule is typically used to treat excessive stomach acid production conditions. It's essential to consult with a healthcare professional to determine if Siz-LS Capsule is appropriate for your specific condition. They can assess your symptoms, medical history, and other factors to provide personalized guidance.

The best time to take Siz-LS Capsule depends on your doctor's specific instructions. However, a common recommendation is to take it before breakfast. This helps the medication effectively reduce stomach acid production throughout the day.

Siz-LS Capsule is more often used to treat gastrointestinal disorders. However, its use may be contraindicated in individuals with allergies to either the drug or its excipients, pregnant or breastfeeding women, those with gastrointestinal bleeding or obstruction, severe kidney or liver impairment, and individuals with certain medical conditions. Before using Siz-LS Capsule , it's essential to consult with a healthcare professional to assess your individual situation and determine if it's safe for you.

Siz-LS Capsule combines two drugs: Rabeprazole (proton pump inhibitor) and Levosulpiride (prokinetic agent).

The safety of Siz-LS Capsule during pregnancy and breastfeeding has not been fully established. If you are pregnant or breastfeeding, it's essential to discuss the risks and benefits of taking Siz-LS Capsule with your doctor.

Yes, dizziness can be a side effect of taking Siz-LS Capsule .

No definitive evidence suggests that using Siz-LS Capsule increases the risk of fractures. If you have concerns about your risk of fractures, it's best to discuss them with your doctor. They can assess your individual situation and provide appropriate advice.

Siz-LS Capsule may cause dizziness and drowsiness. Do not drive or operate machinery unless you are alert.

It's always best to follow the specific storage and disposal instructions provided on the medication packaging or by your pharmacist. If you have any questions or concerns, don't hesitate to ask your healthcare provider.

Common side effects of Siz-LS Capsule may include headache, nausea, vomiting, gas, abdominal pain, dizziness, and diarrhea. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Before using this medication, you should inform your doctor about your medical history, including any ongoing medicines, to avoid potential interactions and minimize side effects.

Take the missed dose as soon as you remember unless it's almost time for your next dose. In this case, skip the missed dose and take your next dose at the regular time. Never take a double dose to make up for a missed one.

Stomach ulcers are sores that develop on the stomach and intestine lining due to erosion of the protective stomach lining. Symptoms include nausea, changes in appetite, bloody or dark stools, unexplained weight loss, vomiting, and indigestion.

Country of origin

India
Other Info - SIZ0087

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Author Details

Santoshini Reddy GDoctor badge

Written By

Santoshini Reddy G

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 18, 2025 | 6:52 AM IST

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Reference

  1. https://www.ciplamed.com/content/rabicip-l-capsuleshttp://www.salvavidaspharma.com/product/rabeprazole-levosulpiride-capsules/
  2. https://www.bionova.co.in/zolppi-l-capsule.html
  3. https://vibcare.co.in/rabeprazole-levosulpiride/

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