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  3. Sitabite DM Tablet 10's

Sitabite DM Tablet 10's, Pack of 10
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Written By Lakshmithulasi Yarragunta ,
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Sitabite DM Tablet is an antidiabetic medicine used to treat Type II Diabetes as an adjunct to diet and exercise. It contains Dapagliflozin (which removes excess sugar from the body via urine), Sitagliptin (which works by increasing the amounts of certain natural substances that lower blood sugar when it is high) and Metformin (which works by reducing the sugar production by cells in the liver and delays sugar absorption from the intestines).

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Composition :

DAPAGLIFLOZIN-10MG + METFORMIN-500MG + SITAGLIPTIN-100MG

Manufacturer/Marketer :

Anthem Bio Pharma

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Sitabite DM Tablet

Sitabite DM Tablet is an antidiabetic medicine used to treat Type II Diabetes. In type 2 diabetes, the pancreas does not produce enough insulin, or the body is unable to use insulin effectively. As a result, blood sugar levels become elevated.

Sitabite DM Tablet contains Dapagliflozin, Sitagliptin, and Metformin. It works by removing excess sugar from the body through urine, increasing the levels of certain natural substances that lower blood sugar when it is high, reducing sugar production by cells in the liver, and delaying sugar absorption from the intestines.

Take Sitabite DM Tablet as advised by your doctor. Sitabite DM Tablet may cause certain side effects such as vomiting, nausea, abdominal pain, headache and stomach upset. Most of these side effects do not need medical attention and resolve over time. If these side effects persist or worsen, please consult your doctor.

Do not take Sitabite DM Tablet if you are allergic to any of its components. Inform your doctor about your medical history and the medicines you are taking, including herbs and supplements, before starting the treatment with Sitabite DM Tablet . Let your doctor know if you are pregnant or breastfeeding before taking Sitabite DM Tablet . It is not recommended for use in children below 18 years of age.

Uses of Sitabite DM Tablet

Sitabite DM Tablet is used in the treatment of Type II Diabetes Mellitus. The detailed uses of Sitabite DM Tablet are as follows:

  • Type 2 Diabetes Management: Sitabite DM Tablet is used to improve blood sugar control in adults with type 2 diabetes. It combines three agents that work together to reduce glucose production, enhance insulin response, and promote glucose excretion through urine.
  • Cardiovascular and Kidney Protection: Sitabite DM Tablet helps lower the risk of heart failure and diabetic kidney disease by improving vascular function, reducing albuminuria, and supporting healthy blood pressure levels.
  • Weight and Metabolic Control: Sitabite DM Tablet supports weight loss and improves metabolic health by reducing excess glucose and enhancing insulin sensitivity, making it beneficial for overweight or obese diabetic patients.
  • HbA1c Reduction and Glycemic Stability: Sitabite DM Tablet effectively lowers HbA1c levels and helps maintain steady blood sugar throughout the day, reducing the risk of hypoglycemia and long-term complications.

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Directions for Use

  • Take Sitabite DM Tablet with food to reduce stomach upset or gastrointestinal side effects.
  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.
  • Swallow the medicine as a whole with a glass of water.
  • Do not crush, break, or chew it.

Medicinal Benefits

  • Sitabite DM Tablet is a combination of three antidiabetic medicines: Sitagliptin, Dapagliflozin, and Metformin, used in the management of Type 2 Diabetes Mellitus, along with proper diet and exercise.
  • Sitagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor that helps increase insulin release and decrease glucagon levels in the body, lowering blood sugar levels when they are high.
  • Dapagliflozin, a sodium-glucose co-transporter 2 (SGLT2) inhibitor, works by removing excess glucose through the urine, thereby lowering blood sugar levels.
  • Metformin is a biguanide which reduces the amount of sugar produced by the liver and delays glucose absorption from the intestine.
  • It improves the body’s sensitivity to insulin, promoting better glucose uptake by muscles and tissues.
  • The combined effect of these three drugs offers multi-targeted control of blood sugar levels, especially in patients not controlled by single or dual therapy.
  • Sitabite DM Tablet helps manage blood glucose levels and prevents diabetes-related complications, such as eye problems, nerve problems, and kidney impairment.

How Sitabite DM Tablet Works

Sitabite DM Tablet contains Dapagliflozin, Sitagliptin, and Metformin. Dapagliflozin removes excess sugar from the body via urine. Sitagliptin works by increasing the amounts of certain natural substances that lower blood sugar when it is high. Metformin works by reducing the sugar production by cells in the liver and delaying sugar absorption from the intestines.

Storage

• Store in a cool and dry place away from sunlight.• Keep Sitabite DM Tablet out of the sight and reach of children.• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Sitabite DM Tablet
Here are the steps to manage the medication-triggered Upper respiratory tract infection:
  • Inform your doctor about the symptoms you're experiencing due to medication.
  • Your doctor may adjust your treatment plan, which could include changing your medication, adding new medications, or offering advice on managing your symptoms.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • Stay hydrated by drinking plenty of fluids to help loosen and clear mucus from your nose, throat, and airways.
  • Get plenty of rest and engage in stress-reducing activities to help your body recover. If your symptoms don't subside or worsen, consult your doctor for further guidance.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • If you experience low blood sugar levels, inform your doctor. They will assess the severity and make recommendations for the next actions.
  • Your doctor will assess your symptoms, blood sugar levels, and overall health before recommending the best course of action, which may include treatment, lifestyle modifications, or prescription adjustments.
  • Follow your doctor's instructions carefully to manage the episode and adjust your treatment plan.
  • Make medication adjustments as recommended by your doctor to prevent future episodes.
  • Implement diet and lifestyle modifications as your doctor advises to manage low blood sugar levels.
  • Monitor your blood sugar levels closely for patterns and changes.
  • Track your progress by recording your blood sugar levels, food intake, and physical activity.
  • Seek further guidance from your doctor if symptoms persist or worsen so that your treatment plan can be revised.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
  • Get ample rest; this helps your stomach to settle.
  • Eat soft and easy-to-digest foods like white rice, bananas, crackers and apple sauce.
  • Include probiotics-rich food like yoghurt, kefir, or miso, as they help maintain gut functioning.
  • Wash your hands properly before preparing/eating food and after using the toilet.
  • Drink water, broth or diluted fruit juice to replace electrolytes and lost fluids.
  • Avoid caffeine, alcohol, high-fat, fried and fast foods, as well as sweetened beverages.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.

What if I have taken an overdose of Sitabite DM Tablet

Please do not exceed the recommended dose, as it might cause an overdose. Signs and symptoms of an overdose of Sitabite DM Tablet may include low blood sugar, stomach pains, feeling or being sick (nausea or vomiting), feeling dizzy and worried. Seek immediate medical attention if you observe these symptoms or think you might have taken too much. Do this even if there are no signs of discomfort or poisoning.

Drug Warnings

  • Sitabite DM Tablet should be avoided if you are allergic to any of the components in it.
  • Before starting treatment, inform your doctor about your medical history and the medications you are taking, including any herbs and supplements. This can help prevent unwanted effects.
  • Sitabite DM Tablet is not recommended for use in patients with severe liver or kidney disease.
  • Consult your doctor if you are pregnant or breastfeeding.
  • It is not recommended for use in children below 18 years of age.
  • Avoid drinking alcohol while on Sitabite DM Tablet  as it increases the risk of hypoglycemia and lactic acidosis (when the lactic acid increases in the body, which impacts the functioning of various organs in the body).

Drug-Drug Interactions

verifiedApollotooltip
SitagliptinGatifloxacin
Critical
DapagliflozinGatifloxacin
Critical

Drug-Drug Interactions

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SitagliptinGatifloxacin
Critical
How does the drug interact with Sitabite DM Tablet:
Co-administration of Sitabite DM Tablet with Gatifloxacin may sometimes affect blood glucose levels. Both high blood glucose and, less frequently, low blood glucose have been reported.

How to manage the interaction:
Taking Sitabite DM Tablet with Gatifloxacin is not recommended as it can lead to a possible interaction, However, it can be taken if advised by the doctor. Consult the prescriber if you experience symptoms such as nervousness, confusion, headache, dizziness, drowsiness, tremors, nausea, hunger, weakness, perspiration, palpitation, rapid heartbeat, increased urination, increased thirst, and increased hunger. Maintaining blood glucose levels is advised. Do not stop using any medications without a doctor's advice.
DapagliflozinGatifloxacin
Critical
How does the drug interact with Sitabite DM Tablet:
Co-administration of Sitabite DM Tablet with Gatifloxacin may sometimes affect blood glucose levels. Both low blood glucose and, less frequently, high blood glucose have been reported.

How to manage the interaction:
Although there is a possible interaction, Gatifloxacin can be taken with Sitabite DM Tablet if prescribed by the doctor. Consult the prescriber if you experience symptoms such as nervousness, confusion, headache, dizziness, drowsiness, tremor, nausea, hunger, weakness, perspiration, palpitation, rapid heartbeat, increased urination, increased thirst, and increased hunger. Maintaining blood glucose levels is advised. Do not discontinue the medication without consulting a doctor.
SitagliptinIvacaftor
Severe
How does the drug interact with Sitabite DM Tablet:
When Sitabite DM Tablet is taken with Ivacaftor, the amount of Sitabite DM Tablet in the blood can go up.

How to manage the interaction:
Taking Sitabite DM Tablet with Ivacaftor together can possibly result in an interaction, but it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
DapagliflozinAliskiren
Severe
How does the drug interact with Sitabite DM Tablet:
Co-administration of Sitabite DM Tablet with Aliskiren may increase the risk of dehydration and low blood pressure.

How to manage the interaction:
If you are supposed to use Sitabite DM Tablet and Aliskiren together, a doctor may adjust the dose and monitor you more frequently. However, if you experience dizziness, fainting, headache, lightheadedness, and/or changes in pulse or heart rate, contact a doctor. Do not discontinue the medication without consulting a doctor.
SitagliptinTirzepatide
Moderate
How does the drug interact with Sitabite DM Tablet:
As tirzepatide and Sitabite DM Tablet both work through similar pathways in the body, it is possible that using them together may result in an increase in side effects.

How to manage the interaction:
It is essential to inform your doctor about all other medications you are taking, including vitamins and herbal supplements. Do not stop using any medications without first talking to your doctor.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Try doing 30 minutes of moderate-intensity physical activity or one hour and 15 minutes of high-intensity exercise weekly.
  • Include whole-grain foods, fruits and veggies, and other fibre-enriched foods.
  • Add omega-3 fatty acid-containing oils for daily cooking.
  • Avoid too much stress, as it may elevate your blood sugar level. To control stress-related blood sugar changes, you can adopt stress management techniques like mindfulness, meditation, or yoga.
  • Weight loss gradually to achieve a healthy body mass index (18.5 to 24.9).
  • Keep your blood pressure as normal (140/90) as possible, as it reduces the risk of cardiovascular diseases in diabetes patients.
  • Avoid smoking and alcohol consumption while on treatment with Sitabite DM Tablet .
  • Take short, frequent meals, and avoid prolonged fasting when taking Sitabite DM Tablet .

Habit Forming

No

Therapeutic Class

ANTIDIABETICS

Sitabite DM Tablet Substitute

Substitutes safety advice
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Alcohol

Unsafe

Alcohol increases the impact of metformin on lactate metabolism. Hence, you should not consume excessive amounts of alcohol, either temporarily or permanently, while taking Sitabite DM Tablet .

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Pregnancy

Consult your doctor

There are no adequate studies on the effect of Sitabite DM Tablet in pregnancy. If you are pregnant or planning pregnancy, inform your doctor before taking Sitabite DM Tablet .

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Breast Feeding

Caution

Sitabite DM Tablet is generally not recommended in breastfeeding. Hence, if you are breastfeeding, inform your doctor before using Sitabite DM Tablet .

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Driving

Safe

Sitabite DM Tablet usually does not affect your ability to drive or operate machinery.

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Liver

Caution

Use Sitabite DM Tablet with caution, as lactic acidosis can occur due to metformin accumulation. The risk increases with hepatic insufficiency. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Kidney

Caution

Renal impairment also increases the risk of lactic acidosis. Hence, Sitabite DM Tablet should be used with caution if you have kidney problems. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Children

Unsafe

Sitabite DM Tablet is not recommended for children below 18 years as the safety and effectiveness were not established.

FAQs

Sitabite DM Tablet is used to treat type II diabetes mellitus, a condition wherein the body doesn't use insulin effectively, which causes unusual blood glucose levels.

Sitabite DM Tablet is a combination medicine containing Sitagliptin that enhances glucose-mediated insulin secretion, thereby reducing fasting and post-prandial blood sugar concentrations. Dapagliflozin helps remove excess sugar from the body via urine. Metformin helps reduce the sugar production by cells in the liver and delays sugar absorption from the intestines.

If you forget to take Sitabite DM Tablet , take it as soon as you remember. However, if it's time for the next dose, avoid taking it and do not double-dose to make up the missed dose. Taking an overdose might cause your sugar level to fall rapidly.

Sitabite DM Tablet may cause certain side effects such as vomiting, nausea, abdominal pain, headache and allergic reactions. If these side effects persist or worsen, please consult your doctor.

Country of origin

India

Manufacturer/Marketer address

No 49, Canara Bank Road, Bommasandra Industrial Area, Phase 1, Hosur Road, Bangalore 560 099, Karnataka, India.
Other Info - SIT0492

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Author Details

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Aug 8, 2025 | 11:12 AM IST

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Reference

  1. https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/022044s022lbl.pdf
  2. https://medlineplus.gov/druginfo/meds/a606023.html
  3. https://www.accessdata.fda.gov/drugsatfda_docs/label/2020/202293s020lbl.pdf
  4. https://www.drugs.com/metformin.html
  5. https://www.nhs.uk/medicines/sitagliptin/about-sitagliptin/#:~:text=Sitagliptin%20is%20prescribed%20for%20people,is%20only%20available%20on%20prescription.

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