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  3. Sinarest-AF Syrup 60 ml

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Sinarest-AF Syrup 60 ml, Pack of 1 SYRUP
Sinarest-AF Syrup 60 ml, Pack of 1 SYRUP
Sinarest-AF Syrup 60 ml, Pack of 1 SYRUP
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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Veda Maddala , M Pharmacy
Sinarest-AF Syrup 60 ml is a combination medicine primarily used in the treatment of allergic rhinitis and common cold. This medicine works by inhibiting the action of histamine, a chemical messenger responsible for causing allergies. It helps relieve congestion, sneezing, nasal and sinus congestion, and nasal swelling caused due to allergies. Common side effects include drowsiness, dizziness, headache, constipation, or trouble sleeping.
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Composition :

CHLORPHENIRAMINE MALEATE-1MG + MENTHOL-1MG + PHENYLEPHRINE-5MG + SODIUM CITRATE-60MG

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Sinarest-AF Syrup 60 ml

Sinarest-AF Syrup 60 ml is a respiratory medication, primarily used to treat symptoms of common cold and allergies. The common cold is a respiratory illness that affects the nose and throat and is caused by viruses known as 'rhinoviruses'. The virus enters the body through the nose, mouth, or eyes and spreads easily through air droplets when a sick person sneezes, coughs or talks. Allergy is an immune response produced by the body in response to 'allergens', which releases 'histamines' into the blood. Histamines are the chemicals released into the body due to this immune response and cause a stuffy nose, watery eyes, itching nose/throat, etc.

Sinarest-AF Syrup 60 ml consists of four medicines, namely: Chlorpheniramine maleate(anti-allergic), Phenylephrine (decongestant), Sodium Citrate (mucolytic), and Menthol (organic compound). Chlorpheniramine maleate belongs to the class of antihistamines (anti-allergic drugs) that works by blocking the action of histamine, a substance responsible for causing allergic reactions. It also provides temporary relief from sneezing, watery and itchy eyes, and runny nose caused by hay fever and other upper respiratory allergies. Phenylephrine is a decongestant that works by contracting and narrowing the blood vessels. It is a vasoconstrictor (narrows blood vessels) and is used as a cardiotonic (favourable effect on the heart) agent. Sodium Citrate is a 'mucolytic agent' that makes sputum less viscous and easier to cough out. Menthol is an organic compound that produces a cooling sensation and relieves throat irritation.

Take Sinarest-AF Syrup 60 ml with or without food as advised by your doctor. Some people may experience nausea, vomiting, headache, and sleepiness. Most of these side effects of Sinarest-AF Syrup 60 ml do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor. 

If you are allergic to Sinarest-AF Syrup 60 ml or any other medicines, please tell your doctor. If you have high blood pressure, diabetes, glaucoma, chronic bronchitis, asthma, chronic obstructive pulmonary disease (COPD), heart disorders, stomach ulcers, overactive thyroid (hyperthyroidism), enlarged prostate gland, epilepsy, pheochromocytoma (tumour in the adrenal glands), kidney, liver, and urinary problems, please inform your doctor before taking Sinarest-AF Syrup 60 ml. If you are pregnant or planning to conceive, it is advised to tell your doctor before taking Sinarest-AF Syrup 60 ml. Do not use Sinarest-AF Syrup 60 ml in breastfeeding mothers without a doctor's advice as it may be excreted into breast milk and cause harm to the baby. Sinarest-AF Syrup 60 ml is not recommended for children below four years of age.

Uses of Sinarest-AF Syrup 60 ml

Treatment of Common cold and allergies

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Directions for Use

• Sinarest-AF Syrup 60 ml can be taken with or without food, or as advised by your doctor.• Follow the recommended dosage and duration advised by the doctor to achieve optimal results.• Check the label for directions before using it. Take the prescribed dose by mouth using the measuring cup provided by the pack.• Avoid using regular household spoons, as they may not measure the dose correctly. Shake well before use.

Medicinal Benefits

Sinarest-AF Syrup 60 ml is a respiratory medication, primarily used to treat symptoms of common cold and allergies. Sinarest-AF Syrup 60 ml consists of four medicines: Chlorpheniramine maleate (anti-allergic), Phenylephrine (decongestant), Sodium Citrate (mucolytic), and Menthol (organic compound). Chlorpheniramine maleate is an antihistamine agent (anti-allergic) that works by blocking the action of histamine, a substance responsible for causing allergic reactions. It also provides temporary relief from sneezing, watery and itchy eyes and runny nose caused by hay fever and other upper respiratory allergies. Phenylephrine is a decongestant that works by contracting and narrowing the blood vessels. It is a vasoconstrictor (narrows blood vessels) and is used as a cardiotonic (favourable effect on heart) agent. Sodium citrate is a mucolytic agent (cough/sputum thinner) that works by thinning and loosening phlegm (mucus) in the lungs, windpipe and nose. Menthol is an organic compound that produces a cooling sensation and relieves throat irritation.

How Sinarest-AF Syrup 60 ml Works

Sinarest-AF Syrup 60 ml consists of four medicines, namely: Chlorpheniramine maleate(anti-allergic), Phenylephrine (decongestant), Sodium Citrate (mucolytic), and Menthol (organic compound). Chlorpheniramine maleate belongs to the class of antihistamines (anti-allergic drugs) that works by blocking the action of histamine, a substance responsible for causing allergic reactions. It also provides temporary relief from sneezing, watery and itchy eyes, and runny nose caused by hay fever and other upper respiratory allergies. Phenylephrine is a decongestant that works by contracting and narrowing the blood vessels. It is a vasoconstrictor (narrows blood vessels) and is used as a cardiotonic (favourable effect on the heart) agent. Sodium Citrate is a 'mucolytic agent' that makes sputum less viscous and easier to cough out. Menthol is an organic compound that produces a cooling sensation and relieves throat irritation.

Storage

• Store in a cool and dry place away from sunlight.
• Keep out of sight and reach of children.
• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Sinarest-AF Syrup 60 ml
  • Avoid driving or operating machinery or activities that require high focus until you know how the medication affects you.
  • Maintain a fixed sleeping schedule, create a relaxing bedtime routine and ensure your sleeping space is comfortable to maximize your sleep quality.
  • Limit alcohol and caffeine as these may worsen drowsiness and disturb sleep patterns.
  • Drink plenty of water as it helps with alertness and keeps you hydrated and for overall well-being.
  • Moderate physical activity can improve energy levels, but avoid intense workouts right before bedtime.
  • Avoid driving or operating machinery or activities that require high focus until you know how the medication affects you.
  • Maintain a fixed sleeping schedule, create a relaxing bedtime routine and ensure your sleeping space is comfortable to maximize your sleep quality.
  • Limit alcohol and caffeine as these may worsen drowsiness and disturb sleep patterns.
  • Drink plenty of water as it helps with alertness and keeps you hydrated and for overall well-being.
  • Moderate physical activity can improve energy levels, but avoid intense workouts right before bedtime.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.

What if I have taken an overdose of Sinarest-AF Syrup 60 ml

Avoid exceeding the recommended dose as it might cause an overdose. Seek medical attention if you experience any unusual symptoms.

Drug Warnings

Let your doctor know if you have any allergic reactions to Sinarest-AF Syrup 60 ml, high blood pressure, diabetes, glaucoma, chronic bronchitis, asthma, chronic obstructive pulmonary disease (COPD), heart disorders, stomach ulcers, overactive thyroid (hyperthyroidism), enlarged prostate gland, epilepsy, pheochromocytoma (tumour in the adrenal glands), kidney, liver and urinary problems before taking Sinarest-AF Syrup 60 ml. If you are pregnant or planning to conceive, it is advised to inform your doctor before taking Sinarest-AF Syrup 60 ml. Do not use Sinarest-AF Syrup 60 ml in breastfeeding mothers without doctor's advice since Chlorpheniramine in Sinarest-AF Syrup 60 ml may be excreted into breast milk and cause harm to the baby. Sinarest-AF Syrup 60 ml is not recommended for children below four years of age. Avoid consuming alcohol along with Sinarest-AF Syrup 60 ml as it could lead to increased drowsiness. Drive only if you are alert since Sinarest-AF Syrup 60 ml may cause sleepiness/shakiness/increased heart rate in some people.

Drug-Drug Interactions

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PhenylephrineSevoflurane
Critical
PhenylephrinePropofol
Critical

Drug-Drug Interactions

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PhenylephrineSevoflurane
Critical
How does the drug interact with Sinarest-AF Syrup 60 ml:
Co-administration of Sinarest-AF Syrup 60 ml with Sevoflurane can increase the levels of Sinarest-AF Syrup 60 ml and lead to side effects.

How to manage the interaction:
Taking Sinarest-AF Syrup 60 ml with Sevoflurane is not recommended, it can be taken if prescribed by the doctor. Do not discontinue the medications without consulting a doctor.
PhenylephrinePropofol
Critical
How does the drug interact with Sinarest-AF Syrup 60 ml:
Taking Sinarest-AF Syrup 60 ml with Propofol may lead to increased levels of Sinarest-AF Syrup 60 ml leading to side effects like high blood pressure.

How to manage the interaction:
Taking Sinarest-AF Syrup 60 ml with Propofol is not recommended, but it can be taken if prescribed by the doctor. Do not discontinue the medications without consulting a doctor.
PhenylephrineSelegiline
Critical
How does the drug interact with Sinarest-AF Syrup 60 ml:
Co-administration of Selegiline with Sinarest-AF Syrup 60 ml together can raise blood pressure.

How to manage the interaction:
Taking Selegiline with Sinarest-AF Syrup 60 ml is not recommended, it can be taken together if prescribed by a doctor. However, consult a doctor immediately if you experience any symptoms such as severe headache, blurred vision, confusion, fits, chest pain, nausea or vomiting, sudden numbness or weakness (especially on one side of the body), speech difficulties, fever, sweating, lightheadedness, and/or fainting Do not discontinue any medications without consulting a doctor.
PhenylephrineTranylcypromine
Critical
How does the drug interact with Sinarest-AF Syrup 60 ml:
Taking Tranylcypromine with Sinarest-AF Syrup 60 ml can increase the risk of high blood pressure.

How to manage the interaction:
Taking Tranylcypromine with Sinarest-AF Syrup 60 ml is not recommended, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience severe headache, blurred vision, confusion, seizures, chest pain, nausea or vomiting, sudden numbness or weakness (especially on one side of the body), speech difficulties, fever, sweating, lightheadedness, and fainting Do not discontinue any medications without consulting a doctor.
PhenylephrineFurazolidone
Critical
How does the drug interact with Sinarest-AF Syrup 60 ml:
Taking Furazolidone with Sinarest-AF Syrup 60 ml can cause an increase in high blood pressure.

How to manage the interaction:
Taking Furazolidone with Sinarest-AF Syrup 60 ml is not recommended, it can be taken if prescribed by the doctor. However, if you experience sudden and severe headache, blurred vision, confusion, seizures, chest pain, nausea or vomiting, sweating, lightheadedness, fainting, sudden numbness or weakness (especially on one side of the body), speech difficulties, fever, consult the doctor immediately. It is advised to use Sinarest-AF Syrup 60 ml only after 14 days of stopping Furazolidone.
ChlorpheniraminePotassium chloride
Critical
How does the drug interact with Sinarest-AF Syrup 60 ml:
Taking Sinarest-AF Syrup 60 ml and Potassium chloride (in tablet or capsule form) together can increase the risk of stomach ulcers, bleeding, and gastrointestinal injury.

How to manage the interaction:
Taking Sinarest-AF Syrup 60 ml with Potassium chloride it not recommended as it can lead to an interaction, it can be taken if your doctor has prescribed it. However, if you experience any symptoms such as severe stomach pain, bloating, lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, or dark, tarry stools, consult the doctor. Do not discontinue any medications without a doctor's advice.
ChlorpheniraminePotassium citrate
Critical
How does the drug interact with Sinarest-AF Syrup 60 ml:
Taking Sinarest-AF Syrup 60 ml and Potassium citrate (in tablet or capsule form) together can increase the risk of stomach ulcers, bleeding, and gastrointestinal injury.

How to manage the interaction:
Taking Sinarest-AF Syrup 60 ml with Potassium citrate is not recommended as it can lead to an interaction, it can be taken if prescribed by the doctor. However, if you experience any symptoms such as severe stomach pain, bloating, lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, or dark, tarry stools, consult the doctor immediately. Do not discontinue any medications without a doctor's advice.
PhenylephrineNortriptyline
Severe
How does the drug interact with Sinarest-AF Syrup 60 ml:
Co-administration of Nortriptyline with Sinarest-AF Syrup 60 ml may lead to side effects like increased blood pressure.

How to manage the interaction:
Although taking Nortriptyline and Sinarest-AF Syrup 60 ml together can result in an interaction, it can be taken if a doctor has prescribed it. Regular monitoring of blood pressure is advised. Do not discontinue any medications without a doctor's advice.
PhenylephrineClomipramine
Severe
How does the drug interact with Sinarest-AF Syrup 60 ml:
Co-administration of Clomipramine and Sinarest-AF Syrup 60 ml together may lead to side effects like increased blood pressure.

How to manage the interaction:
Although taking Clomipramine and Sinarest-AF Syrup 60 ml together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience any unusual symptoms, consult the doctor. Do not discontinue any medications without a doctor's advice.
PhenylephrineHalothane
Severe
How does the drug interact with Sinarest-AF Syrup 60 ml:
Co-administration of Sinarest-AF Syrup 60 ml with Halothane may increase the risk of an irregular heart rhythm.

How to manage the interaction:
Although taking Sinarest-AF Syrup 60 ml with Halothane together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience any symptoms like lightheadedness, fainting, irregular heart beat, dizziness, consult the doctor. Do not discontinue any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Take Sinarest-AF Syrup 60 ml as directed by the doctor and at regular intervals. Do not use other over-the-counter medications, herbal or vitamin supplements without informing your pharmacist or doctor when you take Sinarest-AF Syrup 60 ml.
  • Know your triggers like allergens, such as pollen, dust and food items that make your asthma and other respiratory diseases severe.
  • Quit smoking and avoid passive smoking. Smoking also reduces the effectiveness of the medicine.
  • Drink extra fluids while you take Sinarest-AF Syrup 60 ml to help loosen congestion and lubricate the throat.
  • Eat a healthy diet and exercise regularly to strengthen your breathing muscles and boost your immune system.
  • Learning breathing exercises will help you move more air in and out of your lungs.

Habit Forming

No

Therapeutic Class

ANTIALLERGIC
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Alcohol

Caution

It is not known whether it is safe to consume alcohol with Sinarest-AF Syrup 60 ml. Please consult your doctor before using Sinarest-AF Syrup 60 ml. However, it is better to avoid alcohol to prevent the incidence of side effects like sleepiness.

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Pregnancy

Caution

There is limited data on how Sinarest-AF Syrup 60 ml affects pregnancy. Sinarest-AF Syrup 60 ml may be unsafe to use during pregnancy since it may show harmful effects on the developing baby. Consult your doctor before using Sinarest-AF Syrup 60 ml, if you are pregnant or planning to conceive.

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Breast Feeding

Caution

Sinarest-AF Syrup 60 ml may be unsafe to use during breastfeeding since it has Chlorpheniramine maleate, an anti-histamine drug that may pass into breast milk and harm the unborn baby. Please consult your doctor before starting Sinarest-AF Syrup 60 ml.

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Driving

Caution

Do not drive or operate machinery if you experience sleepiness, dizziness, increased/uneven heart rate and shakiness while using Sinarest-AF Syrup 60 ml. This may affect your ability to drive. Seek medical attention if the symptoms persist longer.

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Liver

Caution

Sinarest-AF Syrup 60 ml should be used with caution in patients with liver diseases. Let your doctor know if you have any history of liver diseases or hepatic impairment. Your doctor will weigh the benefits and potential risks before prescribing Sinarest-AF Syrup 60 ml.

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Kidney

Caution

Sinarest-AF Syrup 60 ml should be used with caution in patients with kidney diseases. Let your doctor know if you have any history of kidney diseases. Your doctor will weigh the benefits and potential risks before prescribing Sinarest-AF Syrup 60 ml.

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Children

Caution

Sinarest-AF Syrup 60 ml is not recommended for use in children less than four years of age. The dose may have to be adjusted by your doctor, depending on the condition of your child's disease and age.

FAQs

Sinarest-AF Syrup 60 ml is a respiratory medication, primarily used to treat symptoms of common cold and allergies.

Sinarest-AF Syrup 60 ml treats symptoms of common cold and allergies and consists of Chlorpheniramine maleate, Phenylephrine, Sodium Citrate, and Menthol. Chlorpheniramine maleate is an antihistamine that blocks the action of histamine (a substance responsible for causing allergic reactions). Phenylephrine is a decongestant that works by contracting and narrowing the nasal blood vessels. Sodium citrate is a cough thinner that works by thinning and loosening phlegm (mucus) in the lungs, windpipe and nose. Menthol is a cooling agent that relieves minor irritation in the throat due to allergy and provides a cooling sensation.

Sinarest-AF Syrup 60 ml should preferably be used after taking your meal to decrease the occurrence of side effects. Please follow your doctor's advice on how you should use this medicine.

Inform your doctor before taking Sinarest-AF Syrup 60 ml, if you have any high blood pressure, diabetes, glaucoma, chronic bronchitis, asthma, chronic obstructive pulmonary disease (COPD), heart disorders, stomach ulcers, overactive thyroid (hyperthyroidism), enlarged prostate gland, epilepsy, pheochromocytoma (tumour in the adrenal glands), kidney, liver and urinary problems.

Take the missed dose as soon as possible. However, if it is time for the next dose, skip the missed dose and go back to your regular dosing schedule.

Store Sinarest-AF Syrup 60 ml according to the instructions on the leaflet and away from direct sunlight. Do not freeze and dispose of unused medicine. Keep it out of reach from pets and children.

You are recommended to complete the dosage duration as prescribed by your doctor. If you do not see any improvement in your symptoms after completing the course, please consult your doctor.

You are recommended to avoid alcohol consumption while taking Sinarest-AF Syrup 60 ml as it may increase sleepiness. Also, avoid driving or operating machinery if you experience dizziness or sleepiness after taking Sinarest-AF Syrup 60 ml.

You are not recommended to take Sinarest-AF Syrup 60 ml if you have high blood pressure as it can suddenly raise your blood pressure and can also reduce the effectiveness of high blood pressure medications.

No, Sinarest-AF Syrup 60 ml is usually not recommended for 2 months old baby. However, always consult a child specialist before using any medication for your child as their organs are sensitive and very delicate.

Sinarest-AF Syrup 60 ml is not used to treat fever. It helps to relieve common cold symptoms without fever. However, always consult a child specialist before using any medication for your child.

Yes, Sinarest-AF Syrup 60 ml is a cough and cold medication used to treat symptoms of the common cold such as runny and stuffy nose, cough, throat irritation and watery eyes. However, use Sinarest-AF Syrup 60 ml for cough only if it is prescribed by your doctor. Do not self-medicate.

No, Sinarest-AF Syrup 60 ml is not an antibiotic. It is a combination medicine used to treat symptoms of common cold and allergies.

Sinarest-AF Syrup 60 ml and Sinarest syrup are medications used to relieve symptoms of common cold and allergies. Sinarest-AF Syrup 60 ml contains chlorpheniramine, phenylephrine, menthol and sodium citrate. Sinarest syrup, designed for children aged 2 to 12 years, includes paracetamol, chlorpheniramine, phenylephrine and sodium citrate. The main difference is their composition and target age groups.

The main difference between Sinarest AF syrup and pediatric drops is their formulation. Both formulations contain the same active ingredients, chlorpheniramine (antiallergic) and phenylephrine (nasal decongestant), menthol and sodium citrate (mucolytic) and are used to provide relief from symptoms of common cold and allergies.

Yes, Sinarest-AF Syrup 60 ml is safe if used as per prescribed dose and duration. The patient should follow doctor’s recommendations.

Yes, Sinarest-AF Syrup 60 ml can cause nausea and vomiting as side effects. Taking it with food, milk, or antacids can avoid nausea. Avoid fried or fatty foods along with Sinarest-AF Syrup 60 ml. If vomiting occurs, drink plenty of water or other fluids by taking small and frequent sips. If vomiting persists and if you notice signs of dehydration such as a low frequency of urination and dark colored and strong-smelling urine, consult your doctor. Do not use any other medicine without consulting your doctor.

Yes, Sinarest-AF Syrup 60 ml may cause drowsiness as the most common side effect. Avoid driving, operating heavy machinery or engaging in other activities that require your full attention. Avoid alcohol consumption or other cough and cold medicines. Also, avoid taking medicines that help you sleep while taking Sinarest-AF Syrup 60 ml as it may cause excessive drowsiness.

No, do not take higher than the recommended dose of Sinarest-AF Syrup 60 ml as it may increase the risk of side effects. If your symptoms worsen while taking Sinarest-AF Syrup 60 ml, please consult the doctor. Do not change the dose of Sinarest-AF Syrup 60 ml without consulting your doctor.

Sinarest-AF Syrup 60 ml may cause side effects such as nausea, vomiting, headache or drowsiness. If any of these side effects persist or worsen, please consult your doctor.

Country of origin

INDIA

Manufacturer/Marketer address

CENTAUR HOUSE, Near Grand Hyatt, Vakola ,Santacruz – East, Mumbai – 400 055, India.
Other Info - SIN0012

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Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Veda MaddalaDoctor badge

Reviewed By

Veda Maddala

M Pharmacy

Last Updated

Jul 18, 2025 | 9:24 AM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Reference

  1. https://www.drugs.com/disease-interactions/acetaminophen-chlorpheniramine-phenylephrine.html
  2. https://www.centaurpharma.com/downloads/Sinarest-Oral-Drops2018.pdf
  3. https://www.drugs.com/drug-interactions/chlorpheniramine.html
  4. https://www.drugs.com/drug-interactions/phenylephrine.html

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