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compositionComposition:ACYCLOVIR-5%W/W
prescription
Prescription Medicine
info
image icons

Setuvir Cream is used to treat Recurrent herpes labialis (cold sores). It contains acyclovir, which exerts antiviral activity against herpes simplex viruses (HSV) by interfering with DNA synthesis and limiting viral replication. Common side effects of Setuvir Cream may include Dry lips, desquamation (scaling or peeling off), dryness of skin, cracked lips, scorching skin, pruritus, flakiness of skin, and stinging on the skin.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

ACYCLOVIR-5%W/W

Manufacturer/Marketer :

Sunways (India) Pvt Ltd

Consume Type :

Topical

Expires on or after :

Dec-28

Return Policy :

Not Returnable

About Setuvir Cream

Setuvir Cream is a topical antiviral medication prescribed to treat cold sores on the face or lips. This soothing cream is designed to target the virus directly, helping to limit its spread and speed up the natural skin healing process. It is most effective when applied at the very first sign of an outbreak, such as tingling or burning.

To achieve the best results, you must apply the cream consistently multiple times a day at regular intervals as directed by your doctor. Be sure to clean your hands thoroughly before and after each application to prevent the virus from spreading. Managing your daily stress levels and keeping your lips protected from harsh sunlight with SPF lip balm can also significantly improve your recovery outcomes.

While using this cream, you may experience mild local skin reactions like temporary dryness, flaking, or a mild stinging sensation. These minor issues typically resolve on their own as your skin adjusts to the treatment. However, if you develop severe skin irritation, swelling, or signs of a serious allergic reaction, you should stop using the product and consult your doctor immediately.

Before using this medicine, discuss any other skin conditions or immune system issues you may have with your healthcare provider. Do not use this cream if you have a known allergy to any of its ingredients. It is also important to remember that this topical product is strictly for external skin use and should not be applied inside the mouth, nose, or eyes.

Because this is a topical product with minimal absorption into the body, it is highly unlikely to interact with oral medications, alcohol, or smoking. However, you should still consult your doctor or pharmacist if you are pregnant, breastfeeding, or managing health conditions in an elderly family member to ensure safe and appropriate use.

Uses of Setuvir Cream

Setuvir Cream helps treat herpes simplex virus (HSV) infections of the skin by slowing the growth and spread of the virus. Your doctor may recommend it for the following conditions:

  • Cold sores (herpes labialis): Setuvir Cream helps reduce the healing time, pain, and tingling associated with recurrent cold sores on the lips and face.
  • Early herpes simplex infections: This cream limits the multiplication of the virus on the skin, helping to keep localized outbreaks from spreading further.

Key Benefits

Setuvir Cream provides targeted, localized relief where you need it most. By applying it directly to the affected area, the medication starts working quickly to manage the virus and soothe your skin. 
Key benefits include:

  • Faster healing time: It shortens the duration of cold sore outbreaks, helping your skin return to normal sooner.
  • Symptom relief: It helps ease the burning, stinging, itching, and pain that typically accompany a viral outbreak.
  • Prevents worsening: Applying the cream early can stop a cold sore from developing into a larger, more painful blister.
Side effects of Setuvir Cream
Here are the steps to manage angioedema (Swelling Under The Skin) as a side effect of medication:
  • If you experience angioedema, inform your doctor immediately. Treatment can help keep the swelling under control.
  • Seek medical attention if symptoms are severe, such as difficulty breathing or swallowing.
  • Follow your doctor's instructions to manage symptoms, which may include stopping or adjusting the medication that triggered angioedema.
  • Your doctor may also recommend antihistamines, steroids, or other treatments to reduce swelling and inflammation.
  • Make dietary and lifestyle changes as recommended, such as avoiding trigger foods or reducing stress.
  • Monitor your condition closely and track your symptoms to report them to your doctor.
  • Consult your doctor again if symptoms worsen or do not improve or if you experience any new or concerning symptoms.
  • If you experience or encounter any severe allergic reaction, stop using medication and consult the doctor right away.
  • Tell your doctor about the allergic reaction, including the medication taken and any symptoms experienced.
  • Your doctor will evaluate the severity of the reaction and determine the best course of action.
  • To ensure a full recovery, follow your doctor's advice, attend scheduled follow-up appointments, and undergo recommended tests to monitor progress and adjust treatment as needed.
  • Skin rash caused by allergies is due to irritants or allergens. Therefore, avoid contact with such irritants.
  • Consult your doctor for proper medication and apply an anti-itch medication. Follow the schedule and use the medication whenever needed.
  • Protect your skin from extreme heat and try to apply wet compresses.
  • Soak in the cool bath, which gives a soothing impact to the affected area.
  • Apply a gentle lip balm with ingredients such as castor seed oil or shea butter.
  • Ensure you are hydrated by drinking plenty of water; this helps heal your lips.
  • Avoid licking your lips or picking at them.
  • Use a humidifier at home, particularly at night, to maintain moisture in the air.
  • Protect your lips from sun exposure by using SPF lip balm and avoid using any irritating components.
  • Stay away from metal objects that could irritate your lips.
  • Consume a vitamin-rich diet to enhance the health of your skin overall.
  • Apply moisturizer immediately after showering or bathing.
  • Use a moisturizer containing lanolin, petroleum jelly, glycerine, hyaluronic acid or jojoba oil.
  • Do not use hot water for bathing. Instead use warm water and limit showers and bath to 5 to 10 minutes.
  • Apply a sunscreen with SPF-30 or higher.
  • Avoid harsh soaps, detergents and perfumes.
  • Do not scratch or rub the skin.
  • Drink adequate water to prevent dehydration.
  • Wear pants, full sleeves and a wide-brimmed hat while going out in the sun.

Directions for Use

  • Setuvir Cream should be applied as prescribed by your doctor, depending on the severity of the viral skin infection.
  • Apply a thin layer to the affected area, including the edges of cold sores or lesions, and gently rub it until absorbed.
  • Avoid contact with eyes, mouth, or inside of the nose, and do not cover the area with tight bandages unless instructed by your doctor.
  • Do not swallow this medication; it is for external use only.

How Setuvir Cream Works

Setuvir Cream contains acyclovir, an antiviral medicine that works by blocking the herpes simplex virus from multiplying. After application, it enters virus-infected skin cells and interferes with the viral enzyme called DNA polymerase, which the virus needs to make copies of its genetic material. By preventing the virus from multiplying, the medicine helps stop the infection from spreading to healthy skin cells. This allows your body's natural immune system to control the infection more effectively, helping cold sores heal faster and reducing symptoms such as pain, tingling, and discomfort.
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Alcohol

Not applicable

No interactions were found. However, avoid alcohol consumption as it can irritate the mouth.

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Pregnancy

Safe if prescribed

Setuvir Cream is generally safe to be used in pregnancy. If you have concerns, discuss them with your doctor before using the Setuvir Cream.

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Breast Feeding

Safe if prescribed

Setuvir Cream is generally safe to be used while breastfeeding. If you have concerns, discuss them with your doctor before using the Setuvir Cream.

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Driving

Safe

Setuvir Cream usually does not impact your ability to drive or operate machinery.

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Liver

Safe if prescribed

No interactions were found. Setuvir Cream can be used safely due to its minimal systemic absorption.

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Kidney

Safe if prescribed

No interactions were found. Setuvir Cream can be used safely due to its minimal systemic absorption.

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Children

Caution

Setuvir Cream is not recommended for use in children below 12 years.

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Heart

Safe if prescribed

No interactions were found. Setuvir Cream can be used safely due to its minimal systemic absorption.

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Geriatrics

Consult your doctor

Please consult a doctor if you have any concerns regarding the use of Setuvir Cream in elderly patients.

What if I have taken an overdose of Setuvir Cream

Since this is a topical cream, an accidental overdose from applying too much to the skin is highly unlikely. However, if the medication is swallowed accidentally, contact your doctor or visit the nearest emergency room immediately for guidance.

Diet & Lifestyle Advise

  • Manage your stress: Stress is a primary trigger for cold sore outbreaks. Practice relaxation techniques like deep breathing, meditation, or regular light exercise.
  • Protect your skin from UV light: Intense sunlight can trigger flare-ups. Wear a wide-brimmed hat and apply a lip balm with SPF 30 or higher once the cream has fully dried.
  • Avoid touching the sores: Keep your hands away from your face to prevent transferring the virus to your eyes, fingers, or other people.
  • Stay hydrated: Drink plenty of water to keep your lips and skin from cracking, which makes them more vulnerable to irritation.
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How Soon It Starts Working

The time required for Setuvir Cream to start to work: The time required for Setuvir Cream to show its action is unknown. The time for which the effects of Setuvir Cream last: The duration of Setuvir Cream’s effect is clinically not established.

What if you forget to take Setuvir Cream

If you forget to apply Setuvir Cream at your scheduled time, apply it as soon as you remember. However, if it is almost time for your next application, skip the missed dose and continue with your regular schedule. Do not apply a double amount to make up for a missed application.

Storage

• Store Setuvir Cream at room temperature, ideally between 15°C and 25°C (59°F and 77°F).

Drug Warnings

  • Start treatment early: For the best results, apply Setuvir Cream at the very first sign of a cold sore, such as tingling, itching, or burning.
  • Inspect the tube: Do not use the cream if the tube is punctured, leaking, or if the cream has changed colour or consistency.
  • Keep it local: Apply this cream only to the skin on your lips and face. Avoid getting it in your eyes, nose, or mouth.
  • Avoid sharing: Cold sores are highly contagious. Never share your tube of Setuvir Cream, towels, or lip products with anyone else.
  • Do not cover with bandages: Allow the treated area to breathe. Avoid covering the cold sore with tight bandages unless instructed by your doctor.

Drug-Drug Interactions

verifiedApollotooltip
  • Other topical skin products: Applying other skin creams, ointments, or cosmetics to the same area at the same time may prevent the active ingredients in Setuvir Cream from absorbing correctly or may increase skin irritation.
No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

verifiedApollotooltip

No clinically significant food interactions are known with Setuvir Cream when used as directed.

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTIVIRALS]

FAQs

It is best to avoid applying makeup, lip balms, or other cosmetics directly over the treated area while using Setuvir Cream, as they can interfere with how well the cream is absorbed. If you must use them, apply Setuvir Cream first, let it dry completely, and then gently apply your other products. Talk to your doctor or pharmacist for advice on suitable skincare products.
No, Setuvir Cream is a topical cream designed only for use on the outside of your lips and face. Applying it inside your mouth can cause severe irritation and is not effective for mouth ulcers or canker sores. Talk to your doctor if you have sores inside your mouth.
If the cream accidentally gets into your eyes, rinse them thoroughly with cool, clean water immediately. If you experience persistent redness, pain, or changes in your vision, seek medical attention right away. Talk to your doctor if you suspect a viral eye infection.
While topical Setuvir Cream is minimally absorbed into the bloodstream, you should always consult your healthcare provider before using it. They will help you weigh the benefits and risks for you and your baby. Talk to your doctor to see if this treatment is appropriate.
No, Setuvir Cream does not cure the herpes simplex virus or remove it from your body. The virus remains dormant in your nerve cells, and the cream only treats active localised outbreaks when they occur. Talk to your doctor about long-term management strategies for recurrent outbreaks.
This medication is generally safe for children, but the appropriate age limit depends on the specific brand and formulation. Always check with a paediatrician before applying any medicated cream to a child's skin. Talk to your doctor for a safe pediatric recommendation.
You should continue using the cream for the full duration prescribed by your doctor, even if the cold sore starts to scab over or look better. Stopping treatment too early may allow the virus to start multiplying again, delaying complete healing. Talk to your doctor if you are unsure when to stop.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

1002-1003, 10th Floor, Windfall, Sahar Plaza, J.B.Nagar, Andheri-Kurla Road, Andheri (East), Mumbai-400059. Maharashtra, India.
Other Info - SE42625
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