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Setcold PD Syrup is used to treat common cold and allergic symptoms like sneezing, watery eyes or itchy/watery nose and throat. It works by blocking the action of histamine, a substance responsible for causing allergic reactions. Also, it helps shrink the blood vessels in the nasal passage, reducing a stuffy nose. Some people may experience drowsiness, nausea, fatigue, dryness in the mouth, headache, and vomiting. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Written By Mrs. Veda Maddala , M Pharmacy
Reviewed By Dr. E Naresh Kumar , MD, MBBS
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More about the Product

Composition :

CETIRIZINE-2.5MG+PARACETAMOL-125MG+PHENYLEPHRINE-2.5MG

Consume Type :

Oral

Expires on or after :

Dec-28

Return Policy :

Not Returnable

About Setcold PD Syrup

Setcold PD Syrup is a medicine designed to relieve the uncomfortable symptoms of the common cold, flu, and upper respiratory allergies. It is medically formulated to target nasal congestion, runny nose, sneezing, fever, and minor body aches. By combining multiple active ingredients into one convenient formulation, it provides comprehensive relief during seasonal illness.

To get the best results, you should take this medicine exactly as prescribed by your doctor, keeping your dosing consistent. You can take Setcold PD Syrup with or without food, but taking it with food may help prevent mild stomach upset. Incorporating simple changes like resting more, staying hydrated, and breathing in warm steam can also make your recovery much faster and smoother.

While taking Setcold PD Syrup, you might experience mild side effects like drowsiness or a dry mouth. However, you must stop taking the medicine and consult your doctor immediately if you experience serious symptoms such as severe dizziness, an irregular heartbeat, or signs of an allergic reaction. Your safety is always the priority, so never ignore unexpected body changes.

Do not take this if you have severe high blood pressure, serious blood vessel disease, or severe liver damage. It is crucial to talk to your doctor before starting this medicine if you have underlying conditions like diabetes, glaucoma, thyroid issues, or difficulty urinating due to an enlarged prostate.

This medicine can interact with other drugs, especially some antidepressants and other cold medicines, which may increase your blood pressure or cause excessive drowsiness. You should also avoid drinking alcohol while on this medication because it increases the strain on your liver. If you are pregnant, breastfeeding, or an older adult, talk to your doctor or pharmacist before taking this product to ensure it is safe for you.

 

Uses of Setcold PD Syrup

Your doctor may prescribe this medicine to treat several conditions, including:

  • Common Cold and Flu: Helps ease the overall discomfort of viral infections by reducing fever, relieving sore throat discomfort, and soothing body aches.
  • Nasal Congestion: Clears blocked nasal passages and sinus pressure, making it much easier to breathe comfortably.
  • Allergic Rhinitis: Controls allergy-related symptoms such as continuous sneezing, itchy nose or throat, and watery eyes.
     

Key Benefits

When taken as prescribed, this medicine offers several important benefits, including:

  • All-in-One Relief from Cold and Allergy Symptoms: It helps manage multiple symptoms together, including fever, nasal congestion, runny nose, sneezing, and watery eyes, reducing the need for multiple separate medicines.
  • Improved Breathing and Reduced Sinus Discomfort: By helping relieve nasal blockage and swelling, it supports easier breathing and reduces discomfort caused by sinus pressure and congestion.
  • Relief from Fever and Allergy-Related Symptoms: The combined action of these 3 components helps lower fever, control allergic reactions, and reduce symptoms such as sneezing and watery eyes for greater comfort.
  • Better Rest and Faster Recovery Support: By easing uncomfortable cold and allergy symptoms, Setcold PD Syrup helps you rest more comfortably and supports a smoother recovery process.
     

Directions for Use

To ensure you get the maximum benefit from Setcold PD Syrup safely, follow these step-by-step instructions:

  • Swallow the tablet whole with a full glass of water.
  • Do not crush, chew, or break the tablet, as this can release the medication too quickly and increase the risk of side effects.
    You may take this medicine with or without food, but taking it with a meal can help if you are prone to a sensitive stomach.
  • Always follow your doctor's exact instructions regarding how often to take this medicine, and do not exceed the recommended duration of treatment.
     

How Setcold PD Syrup Works

Setcold PD Syrup works through the combined action of three distinct active ingredients that target different symptoms simultaneously. Paracetamol: This component acts as a pain reliever and fever reducer. It works by blocking chemical messengers in the brain that signal pain and regulating the body's internal thermostat to lower fever. Phenylephrine: This is a decongestant that relieves a stuffy nose. It works by narrowing the swollen blood vessels in your nasal passages, which reduces swelling, clears blockages, and improves airflow. Cetirizine: This is an antihistamine that addresses allergy symptoms. It blocks histamine, a natural substance your body releases during an allergic reaction, thereby stopping runny noses, watery eyes, and sneezing.
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Alcohol

Caution

Avoid consumption of alcohol with Setcold PD Syrup as it may increase drowsiness. Please consult a doctor before consuming alcohol with Setcold PD Syrup.

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Pregnancy

Caution

The safety of Setcold PD Syrup in pregnant women is unknown. Therefore, it is given to pregnant women only if the doctor thinks the benefits outweigh the risks.

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Breast Feeding

Caution

The safety of Setcold PD Syrup in breastfeeding mothers is unknown. Therefore, it is given to breastfeeding mothers only if the doctor thinks the benefits are greater than the risks.

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Driving

Caution

Setcold PD Syrup may cause drowsiness or tiredness in some people. Therefore, drive only if you are alert after taking Setcold PD Syrup.

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Liver

Caution

Take Setcold PD Syrup with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Take Setcold PD Syrup with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Caution

Setcold PD Syrup is not recommended for children below 12 years of age. However, please consult a doctor before giving Setcold PD Syrup to children.

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Heart

Unsafe

Setcold PD Syrup is not recommended for use in heart patients as it can lead to cardiovascular effects.

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Geriatrics

Caution

Setcold PD Syrup should be given with caution in elderly patients due to an increased risk of side effects. Seek medical advice before using Setcold PD Syrup.

What if I have taken an overdose of Setcold PD Syrup

An overdose of Setcold PD Syrup may cause unpleasant side effects. If you suspect you have taken an overdose, please consult a doctor immediately.

Diet & Lifestyle Advise

  • Stay hydrated: Drink plenty of water, warm herbal teas, or broths to help thin out mucus in your sinuses and throat.
  • Use steam therapy: Inhale steam from a warm shower or use a cool-mist humidifier to keep your nasal passages moist and reduce congestion.
  • Prioritise rest: Give your body time to heal by getting at least 7 to 8 hours of sleep per night and avoiding strenuous physical activity.
  • Avoid irritants: Stay away from secondhand smoke, strong chemical fumes, and cold drafts, which can worsen nasal swelling and trigger coughing fits.
     
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How Soon It Starts Working

The time required for Setcold PD Syrup to start to work: Setcold PD Syrup ideally shows its action within 1 hour after administration.

The time for which the effects of Setcold PD Syrup last: The duration of action for Setcold PD Syrup is unknown.

What if you forget to take Setcold PD Syrup

If you miss a dose of Setcold PD Syrup, take it as soon as you remember. However, if it is almost time for the next dose, skip the missed one and continue with your regular schedule. Do not take a double dose to make up for the missed one.

Storage

•Proper storage ensures that your medicine remains safe and effective. •Store Setcold PD Syrup at room temperature, ideally between 15°C and 30°C.

Drug Warnings

  • Check the Packaging Before Use: Always check the blister pack before taking Setcold PD Syrup. Do not use the medicine if the packaging is broken, punctured, damaged, or shows signs of tampering.
  • Avoid Driving Until You Know Its Effects: Do not drive, ride a bicycle, or operate heavy machinery until you understand how Setcold PD Syrup affects your alertness, as it may cause drowsiness or reduced concentration.
  • Check Other Medicines for Duplicate Ingredients: Before taking any other cough, cold, allergy, or pain relief medicines, check the label carefully to ensure they do not contain the same ingredients, such as paracetamol or decongestants, which may increase the risk of side effects.
  • Limit Caffeine Intake: Reduce consumption of caffeinated drinks such as coffee, tea, and energy drinks, as caffeine may worsen symptoms like restlessness, nervousness, or a fast heartbeat that can sometimes occur with decongestants.
  • Monitor Symptom Improvement: If symptoms do not improve within 3 to 5 days, or if fever becomes worse, stop taking Setcold PD Syrup and consult your doctor for further advice.
     

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Drug-Drug Interactions:

Inform your doctor if you are taking any of the following medicines, as they may interact.

  • Monoamine Oxidase Inhibitors (MAOIs): Do not take this medicine if you have taken an MAOI antidepressant within the last 14 days, as this can cause a dangerous, rapid rise in blood pressure.
  • Other Paracetamol-Containing Products: Combining these can exceed the safe daily limit, significantly increasing your risk of severe liver damage.
  • Blood Thinners: Regular, long-term use of paracetamol may increase the risk of bleeding when taken with medications like warfarin.

Drug-Food Interactions:

  • Alcohol: Avoid drinking alcohol while taking this medicine, as it increases drowsiness and elevates the risk of toxic liver damage.
  • Caffeine: High amounts of caffeine can worsen side effects like restlessness, sleep issues, or a fast heartbeat.


Drug-Disease Interactions:

Inform your doctor if you have a history of the following conditions before taking Setcold PD Syrup, as it may worsen your condition or cause complications.

  • Severe High Blood Pressure or Heart Disease: The decongestant component can narrow blood vessels, which may worsen these conditions.'
  • Liver Disease: Pre-existing liver conditions increase the risk of severe liver damage from paracetamol.
  • Diabetes and Thyroid Disorders: This medicine can occasionally affect blood sugar levels or interact with thyroid functions, so use with caution.

 

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Habit Forming

No

Therapeutic Class

[RESPIRATORY STIMULANTS]

FAQs

Setcold PD Syrup is used to treat the common cold and allergic symptoms like sneezing, watery eyes or itchy/watery nose and throat.
Setcold PD Syrup is composed of three medicines, namely Cetirizine (antihistamine), Phenylephrine‚ (decongestant), and Paracetamol (analgesic and antipyretic). Cetirizine works by blocking the action of histamine, a substance responsible for causing allergic reactions. It helps relieve allergy symptoms such as sneezing, a runny nose, watery eyes, itching, swelling, congestion, or stiffness. Phenylephrine helps shrink the blood vessels in the nostrils and the passage and reduces stuffy noses. Paracetamol works by inhibiting the production of certain chemical messengers in the brain known as prostaglandins responsible for pain and fever.
No, you are not recommended to take Setcold PD Syrup with warfarin as co-administration of these two medicines may increase bleeding risk more easily. However, if you notice blood in urine or stools, dizziness, unusual bleeding or bruising, vomiting, weakness, or headache, please consult a doctor immediately. If you are supposed to use these medicines together, you are advised to contact your doctor so that the dose may be adjusted appropriately to use safely.
It is not recommended to take Setcold PD Syrup along with any anti-depressant medication as it contains phenylephrine, which is known to be contraindicated with anti-depressant medications, especially MAO inhibitors. Setcold PD Syrup should be taken at least 15 days after your last dose of antidepressants.
Yes, Setcold PD Syrup is known to cause nausea or vomiting. In case you are experiencing excessive nausea while consuming Setcold PD Syrup, speak with your doctor.
Store Setcold PD Syrup at room temperature, in a dry place. Keep it out of sight and reach of children.
Setcold PD Syrup may cause side effects like drowsiness, nausea, fatigue, dryness in the mouth, headache, and vomiting. Most of these side effects of Setcold PD Syrup do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.
Setcold PD Syrup is contraindicated in people who are allergic to any of the components in Setcold PD Syrup. Let the doctor know if you have heart problems, stomach ulcers or thyroid problems.
No, taking a higher than the recommended dose of Setcold PD Syrup will not be more effective but may cause unpleasant side effects. Take Setcold PD Syrup as per the dose advised by the doctor.
Serious side effects associated with Setcold PD Syrup are allergic reactions, mouth ulcers, breathing problems, irregular heartbeat, or unexplained bleeding. Consult the doctor if you experience any of these side effects.
You should consult your doctor before taking Setcold PD Syrup while breastfeeding. Some of the active ingredients can pass into breast milk and may affect your baby. Talk to your doctor to evaluate the safest options for you.
No, Setcold PD Syrup is formulated for short-term relief of acute cold, flu, and allergy symptoms like congestion and runny nose. It is not intended to treat chronic respiratory conditions or a chronic cough.
Yes, some individuals may experience mild dizziness or drowsiness while taking Setcold PD Syrup. If you feel dizzy, sit or lie down, and avoid driving or handling machinery.
You should avoid taking Setcold PD Syrup with other pain relievers that contain paracetamol, as this can lead to an accidental overdose and severe liver damage. Always check the active ingredients of any other medication, and talk to your doctor or pharmacist if you are unsure.
This medicine is designed for short-term symptom relief. If your cold or allergy symptoms do not improve after 3 to 5 days, or if your fever worsens, stop taking it.
Yes, the antihistamine in Setcold PD Syrup can sometimes cause dry mouth. You can manage this by sucking on sugar-free hard candies, chewing sugar-free gum, or drinking water frequently.
You should talk to your doctor before taking Setcold PD Syrup if you have glaucoma. Decongestants and antihistamines can sometimes increase pressure inside the eyes, which may worsen certain types of glaucoma.
Take the missed dose as soon as you remember. If it is nearly time for your next scheduled dose, skip the missed one entirely and continue with your normal schedule. Do not take two doses at once.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Reference

  1. Drugs.com Clinical Review Team. Paracetamol Clinical Drug Monograph. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026]Check here
  2. CiplaMed Clinical Compendium. Alerid Colds Product Specification Guide. Mumbai, India: Cipla; 2024. [Accessed on 02 Jun. 2026]Check here
  3. National Health Service (NHS). Paracetamol For Adults - NHS Medicines Reference Guide. London, UK: NHS; 2025. [Accessed on 02 Jun. 2026]Check here
  4. MedlinePlus. A606008 Patient Information Monograph. Bethesda, MD: U.S. National Library of Medicine (NLM); 2025. [Accessed on 02 Jun. 2026]Check here
  5. Drugs.com Clinical Review Team. Cetirizine Patient Clinical Drug Monograph. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026]Check here
  6. Citrizine Citrizine. 2014. [Accessed on 18 Apr. 2019]Check here
  7. Ikon Remedies Ikon Remedies. [Accessed on 16 Sep. 2024]Check here

Country of origin

India
Other Info - SE93316
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