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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy

Senseit-NT Tablet is used for the management of neuropathic pain associated with diabetic peripheral neuropathy, postherpetic neuralgia, spinal cord injury, etc. It contains Pregabalin and Nortriptyline, which affects the chemicals in the brain that send pain signals across the nervous system. Also, it increases nerve transmitters (serotonin and noradrenaline) in the brain, thereby reducing the pain messages arriving in the brain. In some cases, you may experience certain common side effects such as dizziness, sleepiness, nausea, blurred vision, peripheral oedema (swelling of lower legs and hands), weight gain and dry mouth. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Manufacturer/Marketer :

Pharamanova Specialities Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Senseit-NT Tablet

Senseit-NT Tablet is a combination medicine indicated for the management of neuropathic pain associated with diabetic peripheral neuropathy, postherpetic neuralgia, spinal cord injury, etc. Neuropathic pain is a chronic progressive nerve disease which causes nerve pain due to nerve damage or a malfunctioning nervous system.

Senseit-NT Tablet is a combination of two drugs: Pregabalin (anti-convulsant) and Nortriptyline (antidepressant). Pregabalin affects the chemicals in the brain that send pain signals across the nervous system. Nortriptyline works by increasing nerve transmitters (serotonin and noradrenaline) in the brain, thereby reducing the pain messages arriving in the brain. Together, Senseit-NT Tablet helps to treat neuropathic pain.

In some cases, you may experience certain common side-effects such as dizziness, sleepiness, nausea, blurred vision, peripheral oedema (swelling of lower legs and hands), weight gain and dry mouth. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently.

Consult your doctor if you are pregnant or breastfeeding. Senseit-NT Tablet may cause drowsiness and dizziness, so drive only if you are alert. Senseit-NT Tablet should not be given to children as safety and effectiveness have not been established. Avoid consuming alcohol along with Senseit-NT Tablet as it could lead to increased dizziness and sleepiness. Keep your doctor informed about your health condition and medicines to rule out any side-effects.

Uses of Senseit-NT Tablet

Senseit-NT Tablet is used in the treatment of neuropathic pain. The detailed uses of Senseit-NT Tablet are as follows:

  • Neuropathic Pain Management: Senseit-NT Tablet is commonly prescribed to help alleviate pain caused by nerve damage or neuropathy, which can result from conditions such as diabetes or shingles.
  • Management of Epilepsy: Senseit-NT Tablet may be used as part of the treatment plan for patients with epilepsy, specifically for controlling certain types of seizures.
  • Anxiety Disorder Treatment: Senseit-NT Tablet can assist in managing generalized anxiety disorder, providing relief from excessive worry and improving overall emotional well-being.
  • Fibromyalgia Treatment: Senseit-NT Tablet is often utilized to help reduce aches, pain, and discomfort associated with fibromyalgia, enhancing patient’s quality of life.

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Directions for Use

  • Take Senseit-NT Tablet with or without food or as advised by a doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication, to ensure the safety.
  • Swallow the medicine as a whole with glass of water.
  • Do not crush, break, or chew it.

Medicinal Benefits

Senseit-NT Tablet is a combination of two medicines, namely: Pregabalin and Nortriptyline. Senseit-NT Tablet is indicated for the management of neuropathic pain associated with diabetic peripheral neuropathy, postherpetic neuralgia, spinal cord injury, etc. Pregabalin is an anti-convulsant which affects the chemicals in the brain that send pain signals across the nervous system. Nortriptyline is an antidepressant which works by increasing the levels of nerve transmitters (serotonin and noradrenaline) in the brain, thereby reduces the pain messages arriving in the brain. Together, Senseit-NT Tablet helps to treat neuropathic pain (pain due to nerve damage).

How Senseit-NT Tablet Works

Senseit-NT Tablet is a combination of two drugs: Pregabalin (anti-convulsant) and Nortriptyline (antidepressant). Pregabalin affects the chemicals in the brain that send pain signals across the nervous system. Nortriptyline works by increasing nerve transmitters (serotonin and noradrenaline) in the brain, thereby reducing the pain messages arriving in the brain. Together, Senseit-NT Tablet helps to treat neuropathic pain.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

What if I have taken an overdose of Senseit-NT Tablet

Do not take more than the prescribed dose of Senseit-NT Tablet as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

Do not take Senseit-NT Tablet if you are allergic to any of its contents. Inform your doctor before taking Senseit-NT Tablet if you have or had heart problems, bipolar syndrome, severe liver disease or if you have taken MAO inhibitors in the last 14 days. Consult your doctor before taking cough-cold medicines containing adrenaline-like drugs such as ephedrine, phenylpropanolamine, isoprenaline, noradrenaline or phenylephrine. Consult your doctor if you are pregnant or breastfeeding. Senseit-NT Tablet may cause drowsiness and dizziness, so drive only if you are alert. Senseit-NT Tablet should not be given to children as safety and effectiveness have not been established. Avoid consuming alcohol along with Senseit-NT Tablet as it could lead to increased drowsiness and sleepiness.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Senseit-NT Tablet:
Coadministration of Senseit-NT Tablet with Linezolid might raise serotonin hormone levels in the body, affecting the brain and nerve cells. Increased serotonin hormone can lead to side effects.

How to manage the interaction:
Taking Senseit-NT Tablet with Linezolid together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremors, incoordination, stomach cramps, nausea, vomiting, and diarrhea contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Senseit-NT Tablet:
Coadministration of Senseit-NT Tablet with Ziprasidone can increase the risk or severity of irregular heart rhythm.

How to manage the interaction:
Taking Senseit-NT Tablet with Ziprasidone together can result in an interaction, it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, severe or prolonged diarrhea, or vomiting. Do not discontinue any medications without consulting a doctor.
NortriptylinePotassium citrate
Critical
How does the drug interact with Senseit-NT Tablet:
Coadministration of Senseit-NT Tablet with Potassium citrate can increase the risk or severity of gastric bleeding, ulceration, and rarely, perforation leading to serious blood loss.

How to manage the interaction:
Taking Senseit-NT Tablet with Potassium citrate together is not recommended as it can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any unusual bleeding or bruising, dizziness, lightheadedness, abdominal pain, bloating, decreased hunger, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
How does the drug interact with Senseit-NT Tablet:
Coadministration of Senseit-NT Tablet with Safinamide may increase the risk of serotonin syndrome(a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Senseit-NT Tablet with Safinamide together can result in an interaction, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucination(seeing and hearing things that do not exist), fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and loose stools. Do not discontinue any medications without consulting your doctor.
How does the drug interact with Senseit-NT Tablet:
Coadministration of Senseit-NT Tablet with Tranylcypromine can increase the risk of serotonin syndrome(a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Senseit-NT Tablet with Tranylcypromine together can result in an interaction, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucination(seeing and hearing things that do not exist), fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting your doctor.
NortriptylineIsocarboxazid
Critical
How does the drug interact with Senseit-NT Tablet:
Using Senseit-NT Tablet together with Isocarboxazid can increase the risk of serotonin syndrome (A condition resulting from the accumulation of high levels of serotonin in the body. Serotonin is especially a mood stabilizer).

How to manage the interaction:
Taking Isocarboxazid with Senseit-NT Tablet is not recommended, please consult your doctor before taking it. However, if you experience increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasms or stiffness, tremors, incoordination, stomach cramps, nausea, vomiting, and diarrhea call a doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Senseit-NT Tablet:
Co-administration of Senseit-NT Tablet with Selegiline might raise serotonin hormone levels in the body (A condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Taking Senseit-NT Tablet with Selegiline together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience confusion, hallucination, fits, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremors, incoordination, stomach cramps, nausea, vomiting, and diarrhea, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Senseit-NT Tablet:
Coadministration of Senseit-NT Tablet with Zonisamide can increase the risk or severity of side effects like increased body temperature and decreased sweating.

How to manage the interaction:
Taking Senseit-NT Tablet with Zonisamide together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience decreased sweating, fever, drowsiness, dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, severe or prolonged diarrhea, or vomiting, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Senseit-NT Tablet:
When buspirone, is combined with Senseit-NT Tablet can cause serotonin syndrome. Serotonin syndrome is a condition in which a chemical called serotonin builds up in your body, causing signs and symptoms ranging from mild (shivering and diarrhea) to severe (muscle rigidity, fever, and seizures).

How to manage the interaction:
Co-administration of buspirone along with Senseit-NT Tablet can possibly lead to an interaction, it can be taken if recommended by your doctor. However, if you experience symptoms such as confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, incoordination, stomach pain, nausea, vomiting, and diarrhoea, consult the doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Senseit-NT Tablet:
Co-administration of Clonidine and Senseit-NT Tablet may increase the risk and severity of increased blood pressure.

How to manage the interaction:
Although there is a possible interaction between Clonidine and Senseit-NT Tablet, you can take these medicines together if prescribed by your doctor. However, if you experience sweating, nausea, vomiting, dizziness, flushing, stiff neck, headache or heart palpitations, contact a doctor. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Include food rich in vitamin B and D in your diet.
  • Include cayenne pepper in your diet as it can help in lowering neuropathic pain.
  • Exercising regularly helps in improving overall health and combating pain.
  • Rest well, get plenty of sleep.
  • Try taking a warm bath as it can be soothing.
  • Avoid smoking and alcohol consumption.
  • Meditation and yoga can help lower the stress, decrease pain sensitivity and improves coping skills.
  • Acupuncture can be helpful by stimulating pressure points.
  • Using essential oils for massages can help increase circulation.

Habit Forming

No

Therapeutic Class

MISCELLANEOUS

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Alcohol

Unsafe

Avoid consumption of alcohol while taking Senseit-NT Tablet as it may cause increased drowsiness and sleepiness.

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Pregnancy

Caution

Please consult your doctor if you have any concerns regarding this, your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

Consult your doctor before taking Senseit-NT Tablet ; your doctor will decide whether Senseit-NT Tablet can be taken by breastfeeding mothers or not.

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Driving

Unsafe

Senseit-NT Tablet may cause drowsiness, sleepiness and blurred vision. Do not drive or operate machinery unless you are alert.

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Liver

Caution

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Caution

Senseit-NT Tablet should not be given to children as safety and efficacy have not been established.

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Heart

Consult your doctor

Please inform your doctor if you have any pre-existing heart problems

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Geriatrics

Consult your doctor

Limited information available for use of Senseit-NT Tablet in elderly patients. Please consult your doctor.

FAQs

Senseit-NT Tablet is used to treat neuropathic pain associated with diabetic peripheral neuropathy, postherpetic neuralgia, spinal cord injury, etc.

Senseit-NT Tablet affects the chemicals in the brain that send pain signals across the nervous system. It increases nerve transmitters (serotonin and noradrenaline) in the brain, thereby reducing the pain messages arriving in the brain.

Dry mouth could be a side-effect of Senseit-NT Tablet . Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly and chewing sugar-free gum/candy might stimulate saliva and prevent drying of the mouth.

To treat your condition effectually, continue taking Senseit-NT Tablet for as long as prescribed. Do not be reluctant to speak with your doctor if you feel any difficulty while taking Senseit-NT Tablet .

Senseit-NT Tablet is used to treat nerve pain due to diabetic neuropathy. Diabetic neuropathy is a condition in which nerve damage occurs due to high blood glucose levels. It mostly damages the nerves in the legs and feet.

Country of origin

India

Manufacturer/Marketer address

Plot No. 29-33, Ancillary Industrial Area, Deonar Deonar, Govandi Mumbai Mumbai City Mh 400043 In
Other Info - SEN0405

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