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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Selgin 10 mg Tablet is used in the treatment of Parkinson's disease. It contains Selegiline, which increases the level of dopamine and restores its level in the brain. Thereby, improves the symptoms of Parkinson's disease. Some people may experience a sore mouth, swollen gums, loss of balance, difficulty in controlling movements, headache, dizziness, nausea, sleep disorders, mouth ulcers or constipation. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Whats That

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Composition :

SELEGILINE-10MG

Manufacturer/Marketer :

Intas Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Selgin 10 mg Tablet

Selgin 10 mg Tablet belongs to a class of antiparkinson drugs called monoamine oxidase-B inhibitors used in the treatment of Parkinson’s disease. Parkinson’s disease is a central nervous system disorder that affects movement. It causes stiffness, shaking, difficulty in walking, coordination and balance. In Parkinson’s patients, there is a decrease in dopamine (a chemical messenger that is important for movement control) levels as the nerve cells that produce dopamine begin to die.

Selgin 10 mg Tablet contains Selegiline that works by inhibiting the action of an enzyme called monoamine oxidase-B that naturally breaks down dopamine. Thereby, increases the level of dopamine and restores its level in the brain thereby improving the symptoms of Parkinson’s disease.

Take Selgin 10 mg Tablet with or without food as advised by your doctor and swallow whole with a glass of water. Do not crush, chew or break it. Your doctor will advise you how often you take Selgin 10 mg Tablet based on your medical condition. Some people may experience a sore mouth, swollen gums, loss of balance, difficulty in controlling movements, headache, dizziness, nausea, sleep disorders, mouth ulcers or constipation. Most of these side effects of Selgin 10 mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Selgin 10 mg Tablet or any other medicines, please tell your doctor. Avoid taking Selgin 10 mg Tablet if you are pregnant or breastfeeding and consult a doctor. Selgin 10 mg Tablet is not recommended for children. If you are about to undergo any surgery, please inform your doctor that you are taking Selgin 10 mg Tablet as it may interact with certain medicines used as a part of general anaesthesia. Avoid taking Selgin 10 mg Tablet if you have stomach or duodenal ulcers, angina (chest pain), high blood pressure, major heart or blood vessel problems, hyperthyroidism (overactive thyroid gland), fast or irregular heartbeat, narrow-angle glaucoma, pheochromocytoma (tumour of the adrenal gland), prostatic adenoma (tumour of prostate gland), schizophrenia, advanced dementia (loss of memory and other thinking abilities). If you have sleep problems, anxiety, a history of stomach ulcers, kidney or liver problems, any unusual urges like excessive gambling or increased sexual behaviour, inform your doctor before taking Selgin 10 mg Tablet .

Uses of Selgin 10 mg Tablet

Selgin 10 mg Tablet is used in the treatment of Parkinson's disease. The detailed use of Selgin 10 mg Tablet is as follows:<br/>• Treatment of Parkinson's disease: Selgin 10 mg Tablet is used to treat Parkinson's disease, specifically as an adjunct to levodopa/carbidopa therapy in patients who experience deterioration in response quality, helping to improve motor fluctuations and enhance therapeutic effects.<br/>

Directions for Use

• Selgin 10 mg Tablet is usually taken on an empty stomach, or as advised by your doctor.• It is usually taken once in a day or as directed by the doctor.• Swallow it as a whole with a glass of water.• Do not chew, crush or break it.

Medicinal Benefits

Selgin 10 mg Tablet is an antiparkinson agent that is used in the treatment of Parkinson’s disease. In Parkinson’s patients, the nerve cells that produce dopamine (a chemical messenger that is important for movement control) begin to die. So, there is a decrease in dopamine levels. Selgin 10 mg Tablet works by inhibiting the action of the monoamine oxidase-B enzyme that naturally breaks down dopamine. Thereby, increases dopamine in the brain and restores its levels. Thus, it improves the symptoms of Parkinson’s disease. Selgin 10 mg Tablet can be used alone or in combination with other medicines such as levodopa to reduce uncontrolled movements.

How Selgin 10 mg Tablet Works

Selgin 10 mg Tablet contains Selegiline that works by inhibiting the action of an enzyme called monoamine oxidase-B that naturally breaks down dopamine. Thereby, increases the level of dopamine and restores its level in the brain thereby improving the symptoms of Parkinson’s disease.

Storage

Keep Selgin 10 mg Tablet out of the sight and reach of children.

What if I have taken an overdose of Selgin 10 mg Tablet

Do not take more than the prescribed dose of Selgin 10 mg Tablet as it may cause overdose. The symptoms of overdose include dizziness, fainting, drowsiness, agitation, irritability, hallucinations, severe headache, seizures (fits), or sweating. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

If you are known to be allergic to Selgin 10 mg Tablet or any other medicines, please tell your doctor. Avoid taking Selgin 10 mg Tablet if you are pregnant or breastfeeding and consult a doctor. Selgin 10 mg Tablet is not recommended for children. If you are about to undergo any surgery, please inform your doctor that you are taking Selgin 10 mg Tablet as it may interact with certain medicines used as a part of general anaesthesia. Avoid taking Selgin 10 mg Tablet if you have stomach or duodenal ulcers, angina (chest pain), high blood pressure, major heart or blood vessel problems, hyperthyroidism (overactive thyroid gland), fast or irregular heartbeat, narrow-angle glaucoma, pheochromocytoma (tumour of the adrenal gland), prostatic adenoma (tumour of the prostate gland), schizophrenia, advanced dementia (loss of memory and other thinking abilities). If you have sleep problems, anxiety, a history of stomach ulcers, kidney or liver problems, unusual urges like excessive gambling or increased sexual behaviour, inform your doctor before taking Selgin 10 mg Tablet .

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Selgin 10 mg Tablet:
Co-administration of Selgin 10 mg Tablet with Phenylephrine together can raise blood pressure.

How to manage the interaction:
Taking Selgin 10 mg Tablet with Phenylephrine is not recommended, it can be taken together if prescribed by a doctor. However, consult a doctor immediately if you experience any symptoms such as severe headache, blurred vision, confusion, fits, chest pain, nausea or vomiting, sudden numbness or weakness (especially on one side of the body), speech difficulties, fever, sweating, lightheadedness, and/or fainting Do not discontinue any medications without consulting a doctor.
How does the drug interact with Selgin 10 mg Tablet:
Co-administration of Selgin 10 mg Tablet with Propofol may significantly affect the blood pressure.

How to manage the interaction:
Taking Selgin 10 mg Tablet with Propofol together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any symptoms such as severe headache, blurred vision, confusion, fits, chest pain, nausea or vomiting, sudden numbness or weakness (especially on one side of the body), speech difficulties, fever, sweating, lightheadedness, and/or fainting Do not discontinue any medications without consulting a doctor.
How does the drug interact with Selgin 10 mg Tablet:
Co-administration of Selgin 10 mg Tablet with Citalopram can increase the risk of serotonin syndrome (A condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Taking Selgin 10 mg Tablet with Citalopram together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any symptoms such as confusion, hallucination, fits, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Selgin 10 mg Tablet:
Co-administration of Imipramine with Selgin 10 mg Tablet might raise serotonin hormone levels in the body, affecting the brain and nerve cells. Increased serotonin hormone can lead to side effects.

How to manage the interaction:
Taking Imipramine and Selgin 10 mg Tablet together is not recommended as it can result in an interaction. It can be taken if a doctor has advised it. However, if you experience confusion, hallucinations, fits, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, shaking, incoordination, stomach cramps, nausea, vomiting, and diarrhea, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
SelegilineErgotamine
Critical
How does the drug interact with Selgin 10 mg Tablet:
When Ergotamine is taken with Selgin 10 mg Tablet, may increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increases in your body).

How to manage the interaction:
There may be a possibility of interaction between Ergotamine and Selgin 10 mg Tablet, but it can be taken if prescribed by a doctor. If you notice any of these signs - like confusion, hallucination, fits, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramps, nausea, vomiting, and diarrhea-call a doctor. Do not stop using any medications without a doctor's advice.
SelegilineNitrous oxide
Critical
How does the drug interact with Selgin 10 mg Tablet:
Co-ad Nitrous oxide with Selgin 10 mg Tablet can increase the risk and severity of adverse effects.

How to manage the interaction:
-Taking Selgin 10 mg Tablet with Nitrous oxide together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any symptoms such as severe headache, blurred vision, confusion, chest pain, nausea or vomiting, sudden numbness or weakness (especially on one side of the body), speech difficulties, fever, sweating, lightheadedness, and/or fainting Do not discontinue any medications without consulting a doctor.
How does the drug interact with Selgin 10 mg Tablet:
Taking Selgin 10 mg Tablet with Fluvoxamine can increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Fluvoxamine with Selgin 10 mg Tablet can be taken together if prescribed by a doctor. However, contact a doctor immediately if you experience confusion, hallucination (seeing & hearing things that do not exist), seizure(fits), extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor (shaking of hands & legs), incoordination, stomach cramps, nausea, vomiting, and diarrhea. Do not discontinue any medication without consulting a doctor.
How does the drug interact with Selgin 10 mg Tablet:
Taking Carbamazepine with Selgin 10 mg Tablet can cause serotonin syndrome. (Serotonin syndrome is a condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Taking Selgin 10 mg Tablet with Carbamazepine is not recommended, but it can be taken if prescribed by your doctor. However, if you experience symptoms such as confusion, hallucination, fits, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, incoordination, stomach pain, nausea, vomiting, and diarrhea, consult the doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Selgin 10 mg Tablet:
Co-administration of Nortriptyline with Selgin 10 mg Tablet might raise serotonin hormone levels in the body (A condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Taking Nortriptyline with Selgin 10 mg Tablet together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience confusion, hallucination, fits, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremors, incoordination, stomach cramps, nausea, vomiting, and diarrhea, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
SelegilineDexamfetamine
Critical
How does the drug interact with Selgin 10 mg Tablet:
Co-administration of Dextroamphetamine with Selgin 10 mg Tablet can increase the blood pressure.

How to manage the interaction:
There may be a possibility of interaction between Dexamphetamine and Selgin 10 mg Tablet, but it can be taken if prescribed by a doctor. If you notice any of these signs - like severe headache, blurred vision, confusion, fits, chest pain, nausea or vomiting, sudden numbness or weakness (especially on one side of the body), speech difficulties, fever, sweating, lightheadedness, and/or fainting-call a doctor right away. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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SELEGILINE-10MGTyramine-containing food
Moderate

Drug-Food Interactions

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SELEGILINE-10MGTyramine-containing food
Moderate
Common Foods to Avoid:
Pepperoni, Miso Soup, Natto, Ricotta, Salami, Shoyu, Shrimp, Stilton Cheese, Swiss Cheese, Tamari, Tempeh, Fish, Farm Cheese, Fava Beans, Fermented Seafood, Fermented Tofu, Gorgonzola Cheese, Chicken Liver, Chocolates, Cottage Cheese, Cream Cheese, Dried Sausage, Dry-Type Summer Sausages, Cheddar Cheese, Cashews, Camembert, Beef Liver, American Cheese, Almonds, Avocado

How to manage the interaction:
Consuming Selgin 10 mg Tablet with Tyramine-containing food it may increase the blood pressure. Avoid consuming Selgin 10 mg Tablet with Tyramine-containing food.

Diet & Lifestyle Advise

  • Avoid intake of tyramine rich foods such as broad beans, Bovril, mature cheese, fermented soya bean products or yeast extracts.
  • Eat more fibre rich foods to ease constipation.
  • Drink plenty of water to avoid headaches due to dehydration.
  • Avoid consumption of alcohol as it may increase drowsiness.

Habit Forming

No

Therapeutic Class

ANTIPARKINSON AGENTS

Selgin 10 mg Tablet Substitute

Substitutes safety advice
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Alcohol

Unsafe

Avoid consumption of alcohol with Selgin 10 mg Tablet as it may increase the risk of adverse effects such as drowsiness, dizziness or difficulty in concentrating.

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Pregnancy

Unsafe

Selgin 10 mg Tablet is a Category C pregnancy drug and is usually not recommended for pregnant women. Please consult a doctor if you are pregnant as Selgin 10 mg Tablet is given to pregnant women only if the doctor thinks benefits outweigh risks.

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Breast Feeding

Unsafe

Selgin 10 mg Tablet is not recommended for breastfeeding mothers. However, please consult a doctor before taking Selgin 10 mg Tablet if you are a breastfeeding mother.

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Driving

Unsafe

Selgin 10 mg Tablet may cause drowsiness or dizziness and make you fall asleep suddenly. It is an offence to drive if Selgin 10 mg Tablet affects you. Therefore, avoid driving if you feel drowsy or dizzy after taking Selgin 10 mg Tablet .

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Liver

Caution

Take Selgin 10 mg Tablet with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Take Selgin 10 mg Tablet with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Unsafe

Selgin 10 mg Tablet is not recommended for children as the safety and efficacy were not established.

Have a query?

FAQs

Selgin 10 mg Tablet is used in the treatment of Parkinson&#039;s disease.

Selgin 10 mg Tablet contains Selegiline, an antiparkinson agent that works by inhibiting the action of monoamine oxidase-B enzyme that naturally breaks down dopamine. Thereby, increases dopamine in the brain and restores its levels. Thus, improves the symptoms of Parkinson’s disease.

You recommend avoiding tyramine rich foods such as broad beans, Bovril, mature cheese, fermented soya bean products or yeast extracts as it may cause severe high blood pressure.

Selgin 10 mg Tablet may cause low blood pressure in some patients, especially while standing up suddenly from a sitting or lying down position and cause symptoms such as dizziness, sweating, nausea or fainting. Hence, to avoid orthostatic hypotension, you are recommended to get up slowly after lying down or sitting.

Selgin 10 mg Tablet is not recommended for glaucoma (damage of optic nerve that is essential for good vision) patients as it may increase the fluid pressure inside the eye. However, regular monitoring of pressure in the eyes is recommended while on treatment with Selgin 10 mg Tablet .

You are recommended to avoid taking Selgin 10 mg Tablet with escitalopram as it may lead to a severe condition called ‘serotonin syndrome’ and cause symptoms such as blurred vision, stomach cramps, diarrhoea, hallucination, extreme changes in blood pressure, confusion, excessive sweating, increased heart rate, fever, shivering or shaking, tremor, incoordination, muscle spasm or stiffness. However, please consult a doctor before taking Selgin 10 mg Tablet with other medicines.

No, Selgin 10 mg Tablet does not cure Parkinson’s disease. Selgin 10 mg Tablet is only used to reduce the symptoms of Parkinson’s disease.

Selgin 10 mg Tablet should not be used with pain killers like meperidine, tramadol, methadone, propoxyphene and cough syrups containing dextromethorphan. Using together can cause severe side effects and can worsen your present condition.

Selgin 10 mg Tablet is safe if used in the dose and duration prescribed by your doctor. Take it precisely as directed, and do not skip any dose. Follow your doctor’s instructions carefully and inform your doctor if you experience any side effects.

Selgin 10 mg Tablet which contains selegiline, is not classified as a stimulant. However, it can have stimulating effects on the brain, such as causing mood changes, anxiety, agitation, hallucinations, confusion, and sleep disturbances.

No, Selgin 10 mg Tablet is not considered addictive. However, use Selgin 10 mg Tablet as prescribed by your doctor. Do not exceed the recommended dose.

Yes, Selgin 10 mg Tablet should be tapered (changing dose) gradually under the guidance of your doctor. It should not be suddenly stopped as it can cause confusion, sweating, stiff muscles, and high fever. Your doctor will provide a tapering schedule to safely reduce your dosage.

Yes, Selgin 10 mg Tablet is considered neuroprotective. It helps slow down the progression of Parkinson's disease by increasing the amount of dopamine in the brain, which is essential for controlling movement.

Selgin 10 mg Tablet can cause weight loss in some individuals. However, not everyone will experience this side effect. Take a balanced diet with sufficient calories, proteins, fats, and carbohydrates to manage this side effect.

The common side effects of Selgin 10 mg Tablet are sore mouth, swollen gums, loss of balance, difficulty in controlling movements, headache, dizziness, nausea, sleep disorders, mouth ulcers or constipation. If any of these side effects persist or worsen, please consult your doctor.

Country of origin

India

Manufacturer/Marketer address

Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.
Other Info - SEL0040

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