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compositionComposition:OFLOXACIN-200MG+SATRANIDAZOLE-300MG
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Prescription Medicine
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Satrogyl O Tablet is used to treat diarrhoea and dysentery. It helps treat bacterial infections, including intra-abdominal infection, gynaecological and pelvic infections, foot ulcers in diabetes, post-operative infections, dental infections, and infections in immunocompromised patients. It contains two antibiotic medicines, namely: Ofloxacin and Satranidazole, which kill harmful bacteria and parasites (amoebae). In some cases, it may cause side effects such as nausea, vomiting, stomach pain, loss of appetite, dizziness, and headaches. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Written By Veda Maddala , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
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More about the Product

Composition :

OFLOXACIN-200MG+SATRANIDAZOLE-300MG

Manufacturer/Marketer :

Alkem Laboratories Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Satrogyl O Tablet

Satrogyl O Tablet is a prescription medicine used to treat mixed infections of the stomach and intestines, such as severe diarrhoea, dysentery, and pelvic infections. It is specifically formulated to target both harmful bacteria and tiny parasites that cause painful gastrointestinal infections.

To get the best results, you should take this medicine at the exact times prescribed by your doctor and complete the full course even if you start feeling better. It is typically taken with food to prevent an upset stomach. Staying well-hydrated by drinking clean water, clear broths, or oral rehydration solutions is highly recommended during your treatment to support your recovery.

While taking Satrogyl O Tablet , you might experience mild side effects like nausea, a metallic taste in your mouth, or a temporary loss of appetite. If you experience severe watery diarrhoea, extreme dizziness, or a skin rash, you must contact your doctor immediately.

Talk to your doctor before starting this medicine if you have a history of nerve disorders, epilepsy, or liver damage. This medicine should not be taken by anyone with a known allergy to similar classes of antibacterial or antiprotozoal drugs.

This medicine can interact with alcohol, leading to unpleasant reactions like rapid heartbeat, nausea, and headache; therefore, avoid drinking alcohol during your treatment. If you are pregnant, breastfeeding, or planning a pregnancy, consult your doctor or pharmacist before starting Satrogyl O Tablet .

Uses of Satrogyl O Tablet

Your doctor may prescribe this medicine to treat several conditions, including:

  • Diarrhoea and dysentery: Satrogyl O Tablet helps eliminate the specific bacteria and parasites in the digestive tract that cause loose, watery, or bloody stools, helping your bowels return to normal.
  • Mixed abdominal infections: It treats complex infections in the stomach and gut area by clearing out multiple types of harmful microorganisms simultaneously.
  • Gynaecological and pelvic infections: It targets and clears infections in the reproductive organs caused by susceptible anaerobic bacteria and parasites.

Key Benefits

Satrogyl O Tablet provides comprehensive relief from distressing gut symptoms by directly targeting the root cause of the infection.

  • Rarelief from stomach pain and cramping:pid  By clearing out the infection-causing organisms, it reduces gut inflammation and eases painful cramps.
  • Fewer bathroom visits: It quickly controls diarrhoea and dysentery, helping you regain control over your daily routine.
  • Dual-action protection: Because it contains two distinct fighting agents, it successfully clears complex, mixed infections that a single-ingredient medicine might miss.
  • Prevents the infection from spreading: Completing the course ensures that the harmful microbes are fully wiped out, reducing the risk of the infection coming back.
Side effects of Satrogyl O Tablet
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
  • Chest pain may last for a while and needs immediate medical attention as it is a significant health issue to be attended to.
  • Take rest and refrain from doing physical activity for a while, and restart after a few days.
  • Try applying an ice pack to the strained area for at least 20 minutes thrice a day. Ice pack thus helps reduce inflammation.
  • Sit upright and maintain proper posture if there is persistent chest pain. • Use extra pillows to elevate your position and prop your chest up while sleeping.
Here are the steps to Dry Mouth (xerostomia) caused by medication:
  • Inform your doctor about dry mouth symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Drink plenty of water throughout the day to help keep your mouth moist and alleviate dry mouth symptoms.
  • Chew sugar-free gum or candies to increase saliva production and keep your mouth moisturized.
  • Use saliva substitutes, such as mouthwashes or sprays, only if your doctor advises them to help moisturize your mouth and alleviate dry mouth symptoms.
  • Avoid consuming smoking, alcohol, spicy or acidic foods, and other irritants that may aggravate dry mouth symptoms.
  • Schedule regular dental check-ups to keep track of your oral health and handle any dry mouth issues as they arise.
  • Regularly brush and floss your teeth.
  • Rinse your mouth with water and baking soda a solution to neutralize acid in the mouth. This makes your food taste as it should.
  • Drink plenty of water or non-caffeinated drinks to prevent dry mouth which may lead to altered taste.
  • Try ginger, peppermint, fruit or green teas, lemonade, ginger ale or fruit juice to help mask unpleasant tastes.
  • Try sucking on sugar-free ice pops or ice cubes to prevent dry mouth.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
  • Wear cotton underwear and loose pants to facilitate better airflow.
  • Try meditation and yoga to reduce stress and improve balance hormones.
  • Eat foods like yogurt or kefir to support vaginal health.
  • Gently clean the genital area with soap and lukewarm water.
  • Avoid fragrant soap, bubble baths, and douches; these can also irritate.
  • Tell your doctor about any medications or supplements you’re taking, as they may affect vaginal discharge treatments.

Directions for Use

  • Satrogyl O Tablet can be taken with or without food, or as advised by a doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.
  • Swallow Satrogyl O Tablet as a whole with a glass of water.
  • Do not crush, break, or chew it.

How Satrogyl O Tablet Works

Satrogyl O Tablet contains two active medicines that work together to destroy harmful microorganisms. The first active ingredient is ofloxacin, an antibacterial agent that targets the DNA of harmful bacteria. By blocking a crucial enzyme they need to repair and copy their genetic material, it stops the bacteria from growing and multiplying, causing them to die off. The second active ingredient is satranidazole, which targets anaerobic bacteria and protozoa (tiny parasites). It enters these organisms and creates harmful molecules that damage their DNA from within. Once their DNA is broken, these parasites can no longer survive or cause infection. Together, these two actions ensure a thorough cleanup of the gut.
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Alcohol

Caution

Alcohol consumption may worsen the side effects of Satrogyl O Tablet , like dizziness and visual disturbances. It is better to avoid alcohol while you are being treated with Satrogyl O Tablet .

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Pregnancy

Caution

There is limited data on how the Satrogyl O Tablet affects pregnancy. Please consult your doctor if you are planning to become pregnant or are already pregnant before starting Satrogyl O Tablet .

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Breast Feeding

Caution

Satrogyl O Tablet is excreted into the breast milk and may affect the nursing infants. Please consult your doctor before taking Satrogyl O Tablet if you are breastfeeding.

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Driving

Caution

Do not drive or operate machinery if you experience any impairment of skills, dizziness and visual disturbances while using Satrogyl O Tablet .

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Liver

Caution

Please take Satrogyl O Tablet with caution and doctor’s advice if you have a history of liver diseases/conditions.

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Kidney

Caution

Please take Satrogyl O Tablet with caution and doctor’s advice if you have a history of kidney diseases/conditions.

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Children

Unsafe

Satrogyl O Tablet is not recommended for children less than 18 years of age.

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Heart

Caution

Exercise caution while taking Satrogyl O Tablet , if you have any heart conditions.

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Geriatrics

Caution

Satrogyl O Tablet should be given with caution in elderly patients due to an increased risk of side effects. Seek medical advice before using Satrogyl O Tablet .

What if I have taken an overdose of Satrogyl O Tablet

Do not take more than the prescribed dose of Satrogyl O Tablet , as it may cause an overdose. If you suspect you have taken an overdose, please consult a doctor immediately.

Diet & Lifestyle Advise

  • Stay hydrated: Drink plenty of fluids, such as boiled water, coconut water, or oral rehydration salt (ORS) solutions, to replace fluids lost from diarrhoea.
  • Eat bland, easily digestible food: Opt for simple foods like bananas, rice, applesauce, and toast to avoid irritating your gut.
  • Avoid dairy and caffeine: Steer clear of milk, cheese, coffee, and sodas, as they can worsen diarrhoea and interfere with medication absorption.
  • Avoid greasy or spicy foods: High-fat and heavily seasoned meals can trigger stomach cramps and prolong recovery.
  • Practice strict hand hygiene: Wash your hands thoroughly with soap and water before eating and after using the bathroom to prevent spreading the infection.

Health Queries

I have been having watery loose motions for the past two days. Is it safe and effective to take Satrogyl O and Lomfen to treat this condition?

Veda Maddala

Veda Maddala

M Pharmacy

It is not recommended to self-medicate with the combination of satranidazole and ofloxacin, or with loperamide, without a doctor's evaluation. Satranidazole and ofloxacin are powerful antimicrobials meant only for specific bacterial or parasitic infections, while loperamide stops bowel movements. Using drugs like loperamide can sometimes trap harmful pathogens in your gut, potentially worsening your condition. For watery diarrhea, the most crucial step is preventing dehydration. Please drink Oral Rehydration Salts (ORS) and plenty of fluids to stay hydrated, and consult a doctor to get a proper diagnosis and a safe, tailored treatment plan.
health query

Have a query?

How Soon It Starts Working

The time required for Satrogyl O Tablet to start to work: Satrogyl O Tablet ideally shows its action within 1 to 2 hours after administration. The time for which the effects of Satrogyl O Tablet last: The duration of action for Satrogyl O Tablet is unknown.

What if you forget to take Satrogyl O Tablet

If you miss a dose of Satrogyl O Tablet , take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take an extra dose to make up for a missed dose.

Storage

•Proper storage ensures your medicine remains effective and safe to use.. •Store Satrogyl O Tablet tablets at room temperature, ideally between 15°C and 30°C (59°F to 86°F). .

Drug Warnings

  • Complete the entire course: Never stop taking Satrogyl O Tablet early, even if your symptoms clear up, as this can make the infection return and become harder to treat.
  • Strictly avoid alcohol: Do not consume alcohol during treatment and for at least 3 days after finishing your course to avoid severe stomach upset, rapid heartbeat, and vomiting.
  • Protect your skin from the sun: This medicine can make your skin highly sensitive to sunlight. Wear protective clothing and apply a high-SPF sunscreen when going outdoors.
  • Watch for tendon pain: Stop taking the medicine and seek immediate medical help if you experience sudden pain, swelling, or stiffness in any tendon, particularly the Achilles tendon.
  • Be cautious when driving: This medicine may cause dizziness or sleepiness. Do not drive or operate machinery until you know how it affects you.
  • Do not take with antacids: Avoid taking antacids, iron supplements, or multivitamins containing zinc within two hours of taking Satrogyl O Tablet , as they can stop your body from absorbing the medicine.

Drug-Drug Interactions

verifiedApollotooltip

Inform your doctor if you are taking any of the following medicines, as they may interact with Satrogyl O Tablet .

  • Antacids and mineral supplements: Medicines containing magnesium, aluminium, calcium, iron, or zinc can bind to this medicine in your gut and significantly reduce its absorption.
  • Blood thinners (like warfarin): Taking Satrogyl O Tablet alongside blood thinners may increase the risk of bleeding. Your doctor may need to monitor your blood clotting times closely.
  • Corticosteroids: Combining these can increase the risk of tendon inflammation or tendon rupture, especially in older adults.
  • Diabetes medicines: This medicine may alter your blood sugar levels, increasing the risk of low blood sugar. Monitor your blood glucose levels regularly.
Satranidazole + OfloxacinAmiodarone
Critical
Satranidazole + OfloxacinMesoridazine
Critical

Drug-Drug Interactions

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Satranidazole + OfloxacinAmiodarone
Critical
How does the drug interact with Satrogyl O Tablet:
Co-administration of Amiodarone with Satranidazole and Ofloxacin can increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking Amiodarone with Satranidazole and Ofloxacin can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Satranidazole + OfloxacinMesoridazine
Critical
How does the drug interact with Satrogyl O Tablet:
Co-administration of Mesoridazine with Ofloxacin and Satranidazole can increase the risk of irregular heart rhythm and other side effects.

How to manage the interaction:
Although taking Mesoridazine with Ofloxacin and Satranidazole can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, nausea, vomiting, weakness, confusion, tingling in hands or feet, feeling of heaviness in the legs, or slow or rapid heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Satranidazole + OfloxacinZiprasidone
Critical
How does the drug interact with Satrogyl O Tablet:
Co-administration of Ziprasidone with Ofloxacin and Satranidazole can increase the risk of irregular heart rhythm and other side effects.

How to manage the interaction:
Although taking Ziprasidone with Ofloxacin and Satranidazole can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, nausea, vomiting, weakness, confusion, tingling in hands or feet, feeling of heaviness in the legs, or slow or rapid heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Satranidazole + OfloxacinSotalol
Critical
How does the drug interact with Satrogyl O Tablet:
Co-administration of Sotalol with Ofloxacin and Satranidazole can increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking Sotalol with Ofloxacin and Satranidazole can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or slow or rapid heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Satranidazole + OfloxacinBepridil
Critical
How does the drug interact with Satrogyl O Tablet:
Co-administration of Bepridil with Ofloxacin and Satranidazole can increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking Bepridil with Ofloxacin and Satranidazole can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Satranidazole + OfloxacinDronedarone
Critical
How does the drug interact with Satrogyl O Tablet:
Co-administration of Dronedarone with Ofloxacin and Satranidazole can increase the risk of irregular heart rhythm and other side effects.

How to manage the interaction:
Although taking Dronedarone with Ofloxacin and Satranidazole can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, nausea, vomiting, weakness, confusion, tingling in hands or feet, feeling of heaviness in the legs, or slow or rapid heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Satranidazole + OfloxacinCisapride
Critical
How does the drug interact with Satrogyl O Tablet:
Co-administration of Cisapride with Ofloxacin and Satranidazole can increase the risk of irregular heart rhythm and other side effects.

How to manage the interaction:
Although taking Cisapride with Ofloxacin and Satranidazole can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, nausea, vomiting, weakness, confusion, tingling in hands or feet, feeling of heaviness in the legs, or slow or rapid heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Satranidazole + OfloxacinSaquinavir
Critical
How does the drug interact with Satrogyl O Tablet:
Co-administration of Saquinavir with Ofloxacin and Satranidazole can increase the risk of irregular heart rhythm and other side effects.

How to manage the interaction:
Although taking Saquinavir with Ofloxacin and Satranidazole can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, nausea, vomiting, weakness, confusion, tingling in hands or feet, feeling of heaviness in the legs, or slow or rapid heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Satranidazole + OfloxacinQuinidine
Critical
How does the drug interact with Satrogyl O Tablet:
Co-administration of Quinidine with Ofloxacin and Satranidazole can increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking Quinidine with Ofloxacin and Satranidazole can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or slow or rapid heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Satranidazole + OfloxacinThioridazine
Critical
How does the drug interact with Satrogyl O Tablet:
Co-administration of Thioridazine with Ofloxacin and Satranidazole can increase the risk of irregular heart rhythm and other side effects.

How to manage the interaction:
Although taking Thioridazine with Ofloxacin and Satranidazole can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, nausea, vomiting, weakness, confusion, tingling in hands or feet, feeling of heaviness in the legs, or slow or rapid heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip
  • Dairy products and calcium-fortified juices: Avoid taking this medicine with large amounts of milk, yoghurt, or calcium-fortified drinks alone, as calcium can reduce the medicine's absorption. Taking it as part of a full meal is generally fine.
  • Alcohol: Do not consume alcoholic drinks, as it can trigger a severe reaction causing headaches, nausea, fast heartbeat, and flushing.
OFLOXACIN-200MG+SATRANIDAZOLE-300MGCalcium rich foods, Caffeine containing foods/drinks
Moderate

Drug-Food Interactions

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OFLOXACIN-200MG+SATRANIDAZOLE-300MGCalcium rich foods, Caffeine containing foods/drinks
Moderate
Common Foods to Avoid:
Almonds, Bok Choy, Calcium-Fortified Soy Milk, Cheese, Kale, Milk, Ragi, Seasame Seeds, Tofu Set With Calcium, Yogurt, Cocoa, Coffee, Dark Chocolate, Energy Drinks With Caffeine, Green Tea, Kola Nut, Tea, Tiramisu

How to manage the interaction:
Consumption of caffeine, calcium, iron, magnesium, and aluminum containing food while on the treatment with Ofloxacin can lead to decrease in blood levels of Ofloxacin. Avoid or limit consumption of caffeine, calcium, iron, magnesium, and aluminum containing food while on the treatment with Ofloxacin.

All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTIBIOTIC COMBINATION]

FAQs

Satrogyl O Tablet is used to treat diarrhoea and dysentery. It helps treat bacterial infections, including intra-abdominal infection, gynaecological and pelvic infections, foot ulcers in diabetes, post-operative infections, dental infections, and infections in immunocompromised patients.
Satrogyl O Tablet contains Ofloxacin and Satranidazole. These drugs are antibiotics that kill and prevent the bacterial growth that causes diarrhoea, dysentery, and other bacterial infections.
Please let your doctor know if you have a history of allergic reactions to medicines, liver or kidney diseases, high blood pressure, nerve problems (peripheral neuropathy), mental/mood disorders (depression), tendonitis (inflammation of the tendon, a tissue connecting muscle and bone), fits, blood dyscrasia (decreased peripheral blood cell counts), colitis (inflammation of the colon), diabetes, myasthenia gravis (muscle weakness), dehydration and undergoing dialysis treatment.
Satrogyl O Tablet consists of Ofloxacin, a quinolone antibiotic that may cause hypoglycaemia (low blood sugar levels) or hyperglycaemia (high blood sugar levels). It is advised to consult your doctor before using Satrogyl O Tablet and monitor your blood sugar levels regularly.
Do not stop using Satrogyl O Tablet even if you feel better until the doctor's advised course is finished. Your symptoms may improve, but the infection may not be cured completely.
For most healthy individuals, taking ibuprofen with Satrogyl O Tablet is generally safe. However, those with a history of seizures, epilepsy, other nervous system disorders, or kidney problems, as well as those taking medicines that affect the brain, should use this combination with caution and under medical supervision.
Satrogyl O Tablet contains a quinolone antibiotic, Ofloxacin, which can affect live vaccines, such as the typhoid vaccine, and decrease its effectiveness. Please consult a doctor before you start Satrogyl O Tablet if you are undergoing any vaccinations.
It is recommended to maintain a minimum gap of two hours between magnesium/aluminium antacids, sucralfate, zinc or iron preparations and Satrogyl O Tablet .
Satrogyl O Tablet may cause side effects like nausea, vomiting, stomach pain, loss of appetite, dizziness, and headache. Most of these side effects of Satrogyl O Tablet do not require medical attention and typically resolve on their own over time. If these side effects persist longer, please consult your doctor.
Do not exceed the recommended dose as it may cause unpleasant side effects. Consult the doctor if you have taken an overdose of Satrogyl O Tablet .
Consult the doctor if you have no improvement even after taking Satrogyl O Tablet for the prescribed duration. The doctor might adjust the dose or prescribe alternative medicine based on your condition.
Consult your doctor before taking other medications with Satrogyl O Tablet to prevent any potential interactions. Please inform the doctor if you are taking blood thinners, pain medications, or herbal supplements.
Before starting Satrogyl O Tablet , inform the doctor if you are allergic to any of the components in Satrogyl O Tablet , have epilepsy, tendonitis (tendon inflammation), glucose-6-dehydrogenase deficiency, are pregnant or breastfeeding, have a history of mental illness, or have liver/kidney/heart problems.
If you miss a dose of Satrogyl O Tablet , take it as soon as you remember. However, if it is almost time for the scheduled dose, skip the missed dose and take the next dose at the scheduled time.
Alcohol consumption may worsen the side effects of Satrogyl O Tablet , like dizziness and visual disturbances. It is better to avoid alcohol while you are being treated with Satrogyl O Tablet .
Satrogyl O Tablet may cause dizziness, sleepiness and visual disturbances. Therefore, avoid driving or operating machinery unless you are alert.
Store Satrogyl O Tablet at room temperature in a dry place. Keep it out of sight and reach of children.
You should take Satrogyl O Tablet exactly as directed by your doctor. It is highly recommended to take the tablet with a full glass of water and along with food to prevent stomach irritation. Try to take your doses at evenly spaced intervals every day to keep a constant level of the medicine in your system. Talk to your doctor or pharmacist for specific instructions.
If you experience sudden tendon pain, swelling, or inflammation (especially in the ankle or heel), stop taking Satrogyl O Tablet immediately, rest the affected area, and contact your doctor. This medicine is associated with a small risk of tendon inflammation and rupture, which requires urgent medical evaluation.
No, Satrogyl O Tablet is specifically designed to treat infections caused by bacteria and certain parasites. It will not work against viral infections like the common cold, flu, or viral stomach bugs. Using antibiotics unnecessarily can lead to antibiotic resistance, making future bacterial infections harder to treat. Talk to your doctor for an accurate diagnosis.

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Country of origin

India

Manufacturer/Marketer address

Alkem Laboratories Limited, Devashish Building, Alkem House, Senapati Bapat Road, Lower Parel, Mumbai - 400 013.
Other Info - SAT0001
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