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Sartace 2.5mg/50mg Tablet belongs to the group of medications called ‘antihypertensives’ used in the treatment of hypertension (high blood pressure). High blood pressure is a chronic (long-term) condition in which blood pressure is elevated persistently in higher than normal levels. If left untreated, this condition can increase the risk of heart-related diseases like heart attack, heart failure, stroke, irregular heartbeat and other complications.
Sartace 2.5mg/50mg Tablet contains Ramipril and Losartan. Ramipril is an angiotensin-converting enzyme (ACE) inhibitor and works by lowering the body’s production of substances that could narrow the blood vessels and increase blood pressure. Losartan is an angiotensin-II receptor blocker (ARB) that narrows the blood vessels increasing the blood pressure, therefore blocking angiotensin can result in the widening of the narrowed blood vessels. Together, Sartace 2.5mg/50mg Tablet allows the blood to flow more smoothly in the blood vessels.
You should take this medicine exactly as prescribed by the doctor. Sartace 2.5mg/50mg Tablet may cause side effects such as headache, dizziness, hypotension (abnormally low blood pressure), especially when you stand or sit up quickly, dry cough, weakness, stomach pain, diarrhea, indigestion, feeling or being sick, skin rash, chest pain, muscle cramps, hyperkalemia (increased potassium levels in the blood), and hypoglycemia (decreased glucose levels in the blood). If any of these side effects persist or get worse, inform your doctor immediately.
It is not recommended to take Sartace 2.5mg/50mg Tablet if you are allergic to any contents of it, have severe liver impairment, have angioedema (serious allergic reaction), having dialysis treatment, have renal artery stenosis (a kidney problem in which blood supply to the kidney is reduced), and have severe hypotension (abnormally low blood pressure). It is also not recommended for use in children, pregnant and breastfeeding women. The dose may have to be adjusted in elderly people. It is not advised to consume alcohol as it can increase dizziness. Sartace 2.5mg/50mg Tablet may cause dizziness, so do not drive or operate heavy machinery if you feel dizzy.
Sartace 2.5mg/50mg Tablet is used in the treatment of hypertension (high blood pressure). The detailed uses of Sartace 2.5mg/50mg Tablet are as follows:
Sartace 2.5mg/50mg Tablet is used in the treatment of hypertension. It works by lowering the body’s production of substances that could increase blood pressure and also widens narrowed blood vessels. It allows the blood to flow more smoothly in the blood vessels. It can reduce the risk of heart failure, stroke and delay worsening of kidney problems. It can also be given as a treatment for chronic heart failure.
Caution
It is not advised to consume alcohol while taking Sartace 2.5mg/50mg Tablet as it can increase dizziness.
Unsafe
It is not recommended to take Sartace 2.5mg/50mg Tablet while you are pregnant (especially during the second and third trimesters) as it may be harmful to the unborn baby. Consult your doctor before the use of Sartace 2.5mg/50mg Tablet.
Unsafe
It is not recommended to take Sartace 2.5mg/50mg Tablet while you are breastfeeding as it may cause harmful effects on the nursing baby. Consult your doctor before the use of Sartace 2.5mg/50mg Tablet.
Caution
Sartace 2.5mg/50mg Tablet may cause dizziness, so do not drive or operate heavy machinery if you feel dizzy.
Caution
Sartace 2.5mg/50mg Tablet should be given with caution in patients with a history of liver diseases. The dose may be adjusted by your doctor as required.
Caution
Sartace 2.5mg/50mg Tablet should be given with caution in patients with a history of kidney diseases. The dose may be adjusted by your doctor as required.
Unsafe
Sartace 2.5mg/50mg Tablet is not recommended for use in children as the efficacy and safety have not been established.
Safe if prescribed
Sartace 2.5mg/50mg Tablet is generally safe for heart patients if prescribed, but should be used under medical supervision.
Caution
Elderly patients may require caution and dose adjustments, as Sartace 2.5mg/50mg Tablet may increase the risk of side effects.

Have a query?
Before taking Sartace 2.5mg/50mg Tablet, inform your doctor if you have heart, kidney or liver problems. Sartace 2.5mg/50mg Tablet may sometimes cause a decrease in blood pressure than normal, especially in dehydrated people are taking diuretics (medicines to treat edema) and have low levels of sodium. Regularly check your blood pressure levels to avoid any risk. Sartace 2.5mg/50mg Tablet should also be used with caution in patients who are taking treatment for allergy, have hyperkalemia (high potassium levels), have adrenal gland problems and have systemic lupus erythematosus (a skin disease).
Drug-Drug Interactions: Sartace 2.5mg/50mg Tablet may interact with non-steroidal anti-inflammatory drugs (NSAIDs) (ibuprofen and indomethacin), pain killer(aspirin), medicines used for the treatment of low blood pressure, shock, cardiac failure, or allergies (ephedrine, noradrenaline), medicine used to treat long-term heart failure (sacubitril+valsartan), medicine that suppress immune system (ciclosporin, sirolimus, and everolimus), water pill (furosemide), medicines which can increase the amount of potassium in your blood (spironolactone, triamterene, amiloride, trimethoprim and trimethoprim+sulfamethoxazole), blood thinner (heparin), steroid medicine (prednisolone), medicine to treat gout (allopurinol), medicine to treat heart rhythm problems (procainamide), medicines used to treat cancer (temsirolimus and amifostine), antipsychotics, medicine used to treat type 2 diabetes (vildagliptin and insulin), medicine used to treat diarrhea (racecadotril), medicine to treat high blood pressure (aliskiren), and antidepressants (baclofen and lithium).
Drug-Food Interactions: Sartace 2.5mg/50mg Tablet may interact with alcohol and increase dizziness.
Drug-Disease Interactions: Sartace 2.5mg/50mg Tablet should not be used in patients with liver impairment, angioedema (serious allergic reaction), under dialysis treatment, renal artery stenosis (a kidney problem in which blood supply to the kidney is reduced) and severe hypotension (abnormally low blood pressure).
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Sartace 2.5mg/50mg Tablet is used to treat hypertension (high blood pressure).
Sartace 2.5mg/50mg Tablet contains Ramipril and Losartan. Ramipril is an angiotensin-converting enzyme (ACE) inhibitor and works by lowering the body’s production of substances that could narrow the blood vessels and increase blood pressure. Losartan is an angiotensin-II receptor blocker (ARB) which narrows the blood vessels increasing the blood pressure, therefore blocking angiotensin can result in widening of the narrowed blood vessels. Together, Sartace 2.5mg/50mg Tablet can effectively reduce blood pressure and prevent complications associated with it.
Sartace 2.5mg/50mg Tablet can be safely taken as long as your doctor has prescribed it to you. High blood pressure is a life-long condition and you should not abruptly stop taking the medicine. Discontinuing Sartace 2.5mg/50mg Tablet may lead to increased blood pressure with a high risk of heart attack and stroke in the future.
Please inform your doctor before surgery if you are taking Sartace 2.5mg/50mg Tablet as it needs to be stopped. Sartace 2.5mg/50mg Tablet might lower the blood pressure further if taken along with general anesthesia.
Sartace 2.5mg/50mg Tablet may cause side-effects such as headache, dizziness, hypotension (abnormally low blood pressure), especially when you stand or sit up quickly, dry cough, weakness, stomach pain, diarrhea, indigestion, feeling or being sick, skin rash, chest pain, muscle cramps, hyperkalemia (increased potassium levels in the blood) and hypoglycemia (decreased glucose levels in the blood). If any of these side-effects persist or get worse, inform your doctor immediately.
Sartace 2.5mg/50mg Tablet is probably safe for diabetic patients if it is prescribed by a doctor. Sartace 2.5mg/50mg Tablet protects the kidney and slows down the decrease of kidney function in hypertensive (high blood pressure) and type 2 diabetic patients.
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