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  3. SAMLOKIND 2.5MG TABLET

SAMLOKIND 2.5MG TABLET, Pack of 10 TABLETS
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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
SAMLOKIND 2.5MG TABLET is used to treat high blood pressure and angina (chest pain). It contains S-amlodipine which works by relaxing the blood vessels; this reduces the heart's workload and makes the heart more efficient at pumping blood throughout the body. In some cases, this medicine may cause side effects such as fatigue, headache, nausea, dizziness, and abdominal pain. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Composition :

S AMLODIPINE-2.5MG

Manufacturer/Marketer :

Mankind Pharma Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

NPPA :

Regulated

About SAMLOKIND 2.5MG TABLET

SAMLOKIND 2.5MG TABLET is used to treat hypertension (high blood pressure) and angina (chest pain). Hypertension (high blood pressure) is a lifelong or chronic condition in which the blood pressure against the artery walls becomes high. The higher this blood pressure, the harder the heart has to pump. 

SAMLOKIND 2.5MG TABLET contains 'S-amlodipine', a calcium channel blocker that acts by relaxing the blood vessels. This reduces the heart's workload and makes the heart more efficient at pumping blood throughout the body. Thus, it helps to lower high blood pressure, reducing the chances of heart attack or stroke.

Take SAMLOKIND 2.5MG TABLET with or without food as prescribed by your doctor with a full glass of water. SAMLOKIND 2.5MG TABLET may be prescribed alone or in combination with other blood pressure-lowering medicines, depending upon your blood pressure levels. Inform your doctor if you are taking any other anti-hypertensive medicine. You may have common side effects like fatigue, ankle swelling, sleepiness, flushing (sense of warmth in the face, ears, neck, and trunk), headache, nausea, dizziness, palpitations, and abdominal pain that usually resolves after some time. You must closely monitor your blood pressure if you have ever had a stroke or heart attack or are currently taking other blood pressure-lowering pills. It is advised to continue taking this drug and do not stop taking it suddenly without consulting your doctor.

Inform your doctor if you are allergic to SAMLOKIND 2.5MG TABLET. Inform your doctor if you are pregnant or are planning to get pregnant, are breastfeeding, have liver disease, kidney disease, heart failure, Shock (including cardiogenic shock), obstruction of the outflow tract of the left ventricle (e.g., high-grade aortic stenosis), unstable angina (excluding Prinzmetal's angina), severe hypotension, hemodynamically unstable heart failure after acute myocardial infarction.

Uses of SAMLOKIND 2.5MG TABLET

Treatment of High blood pressure (hypertension), Heart-related chest pain (angina), and Prevention of a heart attack.

Directions for Use

• Take SAMLOKIND 2.5MG TABLET with or without food as advised by your doctor.• It is advised to take SAMLOKIND 2.5MG TABLET once daily; however, follow your doctor’s recommendation regarding the dosage and duration.• Swallow it as a whole with a glass of water.• Do not crush or chew it.

Medicinal Benefits

SAMLOKIND 2.5MG TABLET is used to treat heart-related conditions like angina (chest pain) and high blood pressure (hypertension). It is a calcium channel blocker that inhibits the entry of calcium (ions) across the heart which relaxes and widens the smooth muscles for better blood flow. Besides this, SAMLOKIND 2.5MG TABLET helps prevent sudden spasms of the coronary artery (blood vessels of the heart) and reduces how hard the heart has to pump blood around the body, lowering its oxygen requirements. It improves an individual’s tolerance to physical activity and exercise and keeps their blood pressure normal during exercise. As a result, it overall protects your heart and keeps your heart healthy.

How SAMLOKIND 2.5MG TABLET Works

SAMLOKIND 2.5MG TABLET contains 'S-amlodipine', a calcium channel blocker that acts by relaxing the blood vessels. This reduces the heart's workload and makes the heart more efficient at pumping blood throughout the body. Thus, it helps to lower high blood pressure, reducing the chances of heart attack or stroke.

Storage

stored at room temperature below 30°C

What if I have taken an overdose of SAMLOKIND 2.5MG TABLET

Avoid exceeding the recommended dose as it could lead to an overdose. Symptoms of overdose may include excessive peripheral vasodilation with marked low blood pressure and reflex tachycardia. If you experience these symptoms or suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

SAMLOKIND 2.5MG TABLET should not be given to people allergic to SAMLOKIND 2.5MG TABLET, have low blood pressure (less than 90 mm of Hg), have had a heart attack, kidney disease, liver disease, pregnant women, or planning to get pregnant and breastfeeding women without the prescription of a doctor. Besides this, it is contraindicated in patients with aortic stenosis (heart valve problem). SAMLOKIND 2.5MG TABLET can pass into breast milk, but its effect on the baby is not known. So, it is better to tell your doctor if you are taking SAMLOKIND 2.5MG TABLET and breastfeeding. SAMLOKIND 2.5MG TABLET is not recommended for use in patients with a known history of hypotension or cardiogenic shock due to the increased risk of worsening the patient's condition. SAMLOKIND 2.5MG TABLET should be used with caution in patients with coronary artery disease due to the increased risk of worsening the patient's condition. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Drug-Drug Interactions

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S-AmlodipineCarbamazepine
Severe
S-AmlodipineCeritinib
Severe

Drug-Drug Interactions

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S-AmlodipineCarbamazepine
Severe
How does the drug interact with Samlokind 2.5mg Tablet:
Taking carbamazepine and Samlokind 2.5mg Tablet together may possibly reduce the blood levels of Samlokind 2.5mg Tablet, which could reduce its treatment outcomes.

How to manage the interaction:
Although taking Carbamazepine and Samlokind 2.5mg Tablet together can possibly result in an interaction, it can be taken if your doctor has prescribed it. Do not stop taking any medications without consulting your doctor.
S-AmlodipineCeritinib
Severe
How does the drug interact with Samlokind 2.5mg Tablet:
Co-administration of Ceritinib together with Samlokind 2.5mg Tablet can slow your heart rate and increase the risk of an irregular heart rhythm which can be severe. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Co-administration of Ceritinib and Samlokind 2.5mg Tablet can lead to an interaction, but they can be taken if advised by your doctor. However, if you experience any symptoms of sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
S-AmlodipineMitotane
Severe
How does the drug interact with Samlokind 2.5mg Tablet:
Co-administration of Mitotane and Samlokind 2.5mg Tablet can reduce the blood levels of Samlokind 2.5mg Tablet.

How to manage the interaction:
Co-administration of Mitotane and Samlokind 2.5mg Tablet can lead to an interaction, but they can be taken if advised by your doctor. Do not stop using any medications without a doctor's advice.
S-AmlodipinePhenytoin
Severe
How does the drug interact with Samlokind 2.5mg Tablet:
Co-administration of Phenytoin and Samlokind 2.5mg Tablet can reduce the blood levels of Amlodipine.

How to manage the interaction:
Co-administration of Phenytoin and Samlokind 2.5mg Tablet can lead to an interaction, but they can be taken if advised by a doctor. Do not stop using any medications without a doctor's advice.
S-AmlodipineSimvastatin
Severe
How does the drug interact with Samlokind 2.5mg Tablet:
Co-administration of Simvastatin and Samlokind 2.5mg Tablet together can increase the blood levels of simvastatin and increase the risk of side effects such as liver damage and rhabdomyolysis (breakdown of skeletal muscle tissue).

How to manage the interaction:
Taking of Simvastatin and Samlokind 2.5mg Tablet can lead to interaction, but they can be taken if advised by your doctor. However, if you experience any symptoms like muscle pain, tenderness, weakness, fever, dark-coloured urine, chills, joint pain, swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, and yellowing of the skin or eyes, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
S-AmlodipineRifapentine
Severe
How does the drug interact with Samlokind 2.5mg Tablet:
The combined use of Rifapentine and Samlokind 2.5mg Tablet can reduce the blood levels of Amlodipine.

How to manage the interaction:
Co-administration of Rifapentine and Samlokind 2.5mg Tablet can lead to an interaction, but they can be taken if advised by your doctor. consult a doctor if your symptoms do not improve. Do not stop using any medications without a doctor's advice.
S-AmlodipineItraconazole
Severe
How does the drug interact with Samlokind 2.5mg Tablet:
Coadministration of Amlodipine with Itraconazole may significantly raise the blood levels and effects of Amlodipine.

How to manage the interaction:
Coadministration of Amlodipine and Itraconazole may interact, but if prescribed by a doctor, they can be used together. Consult a doctor if you develop chest discomfort, trouble breathing, dizziness or fainting, swelling of the hands, ankles, or feet, or any other of these symptoms. Do not discontinue any medications without consulting a doctor.
S-AmlodipineDolasetron
Severe
How does the drug interact with Samlokind 2.5mg Tablet:
Taking Dolasetron and Samlokind 2.5mg Tablet together can increase the risk of an irregular heart rhythm.

How to manage the interaction:
The combined use of Dolasetron and Samlokind 2.5mg Tablet can lead to an interaction, but they can be taken if advised by your doctor. However, if you experience any symptoms like dizziness, lightheadedness, fainting, or irregular heartbeat, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
S-AmlodipineTizanidine
Severe
How does the drug interact with Samlokind 2.5mg Tablet:
Co-administration of Tizanidine and Samlokind 2.5mg Tablet together may have additive effects in lowering your blood pressure.

How to manage the interaction:
Co-administration of Tizanidine and Samlokind 2.5mg Tablet can lead to an interaction, but it can be taken if your doctor advises. However, if you experience any symptoms like headache, dizziness, lightheadedness, fainting, and changes in pulse or heart rate, consult the doctor immediately. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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S AMLODIPINE-2.5MGCalcium rich foods
Moderate

Drug-Food Interactions

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S AMLODIPINE-2.5MGCalcium rich foods
Moderate
Common Foods to Avoid:
Tofu Set With Calcium, Ragi, Seasame Seeds, Kale, Milk, Almonds, Bok Choy, Calcium-Fortified Soy Milk, Cheese, Yogurt

How to manage the interaction:
Calcium-containing products may decrease the effectiveness of calcium channel blockers by saturating calcium channels with calcium. monitoring the effectiveness of calcium channel blocker therapy during co-administration with calcium products.

Diet & Lifestyle Advise

  • Keep your weight under control with a BMI of  19.5-24.9.

  • Do regular physical activity or exercise for at least 150 minutes per week, or about 30 minutes most days of the week. Doing this can help you to lower your raised blood pressure by about 5 mm of Hg.

  • Opt for a diet rich in whole grains, fruits, veggies, and low-fat dairy products.

  • Limit intake of sodium chloride (table salt) in your daily diet to 2300 mg per day or less than 1500 mg is ideal for most adults.

  • If you are taking alcohol, then only one serving for women and two servings for men is advisable.

  • Quitting smoking is the best strategy to lower the risk of heart disease.

  • Avoid chronic stress as it can raise your blood pressure. Try to enjoy and spent time with your loved ones to cope with stress and practice mindfulness techniques.

  • Monitor your blood pressure daily and if there is too much fluctuation, then immediately contact your doctor.

  • Try to include heart-healthy omega-3 fatty acid-containing food drinks in your daily diet. You can also use low-fat cooking oil like olive oil, soybean oil, canola oil, and coconut oil to lower your elevated blood pressure.

Habit Forming

No

Therapeutic Class

ANTI- HYPERTENSIVES

SAMLOKIND 2.5MG TABLET Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Unsafe

You are recommended not to consume alcohol along with SAMLOKIND 2.5MG TABLET to avoid unpleasant side effects like lowering of blood pressure (hypotension).

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Pregnancy

Caution

SAMLOKIND 2.5MG TABLET is not recommended for use in pregnant women unless necessary. All the risks and benefits should be discussed with the doctor before taking SAMLOKIND 2.5MG TABLET.

bannner image

Breast Feeding

Caution

SAMLOKIND 2.5MG TABLET is not recommended for use in breastfeeding women unless necessary. All the risks and benefits should be discussed with the doctor before taking this medicine

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Driving

Unsafe

Drive with caution, SAMLOKIND 2.5MG TABLET usually causes drowsiness and affects driving ability.

bannner image

Liver

Caution

SAMLOKIND 2.5MG TABLET should be used with caution, especially if you have or have had a history of liver disease. Your doctor will have to change the dosage depending on your medical condition and your reaction to treatment.

bannner image

Kidney

Caution

SAMLOKIND 2.5MG TABLET is generally safe to prescribe in patients with kidney diseases, and dose adjustment is generally not required. However, your doctor will decide the appropriate dosage strength depending upon the severity of your condition.

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Children

Caution

SAMLOKIND 2.5MG TABLET can be given safely to children aged 6-12 years provided, the dose has been prescribed by a child specialist. SAMLOKIND 2.5MG TABLET should not be given to the children without consulting a child specialist.

Have a query?

FAQs

SAMLOKIND 2.5MG TABLET is used to treat hypertension (high blood pressure) and angina (chest pain).

SAMLOKIND 2.5MG TABLET contains S-amlodipine, a calcium channel blocker that acts by relaxing the blood vessels. This reduces the heart's workload and makes the heart more efficient at pumping blood throughout the body. Thus, it helps to lower high blood pressure, reducing the chances of heart attack or stroke.

The common side effects of SAMLOKIND 2.5MG TABLET are fatigue, ankle swelling, sleepiness, flushing (sense of warmth in the face, ears, neck, and trunk), headache, nausea, dizziness, palpitations, and abdominal pain resolves after some time.

No, you are advised to inform your doctor and monitor your blood pressure for at least two weeks before stopping the medicine. Depending upon your current blood pressure readings, there is a possibility your doctor may lower your medicine dosage and will not recommend discontinuing it.

In case you have missed a dose of SAMLOKIND 2.5MG TABLET, you are advised to take it as soon as you remember. However, try not to miss a dose in the first place, if it's time for you to take your next dose, then do not take both doses together. Take only one dose, taking a double dose of SAMLOKIND 2.5MG TABLET will lead to low blood pressure.

Yes, SAMLOKIND 2.5MG TABLET is known to cause ankle swelling upon long-term use. Please try to keep your feet up when sitting for long hours. If the problem persists still, consult your doctor and do as advised.

No, you should notify your doctor and monitor your blood pressure for at least two weeks before quitting the medication. Depending on your current blood pressure readings, your doctor may reduce your drug dosage but will not advocate quitting it.

Eating well, exercising regularly, maintaining a healthy weight, quitting smoking, getting enough sleep, and managing stress are all lifestyle changes that can help lower blood pressure.

Uncontrolled hypertension gradually destroys the arteries, causing them to harden. As the arteries constrict and become less flexible, the heart works harder to circulate blood. Uncontrolled high blood pressure can cause a stroke, heart attack, heart failure, and other heart problems, damage to the kidneys, memory, and eyesight, and contribute to erectile dysfunction.

SAMLOKIND 2.5MG TABLET begins to act on the day you take it, but it may take a few weeks before it has full effect.

SAMLOKIND 2.5MG TABLET may cause itching, although it is not common in everyone. It usually fades with time; however, contact your doctor if you experience severe itching.

SAMLOKIND 2.5MG TABLET is generally safe to prescribe in patients with mild kidney dysfunctions, and dose adjustment is generally not required. However, your doctor will decide the appropriate dosage strength depending on the severity of your condition.

You can take it at any time of day but try to make sure it's around the same time every day.

Usually, treatment with SAMLOKIND 2.5MG TABLET is long term, even for the rest of your life. Talk to your doctor if you want to stop taking SAMLOKIND 2.5MG TABLET.

No, SAMLOKIND 2.5MG TABLET is not a beta-blocker. It belongs to a class of medicines known as calcium channel blockers.

More frequent or more severe chest pain, rapid, pounding, or irregular heartbeat and fainting. If you experience any of these symptoms, call your doctor immediately or get emergency medical treatment.

SAMLOKIND 2.5MG TABLET does not interfere with contraception. However, some hormonal methods of contraception, such as the combination pill and contraceptive patch, are generally not indicated if you have high blood pressure.

Consuming significant amounts of grapefruit or grapefruit juice can raise the levels of amlodipine in your blood and exacerbate adverse effects. If you are affected, you may need to avoid eating or drinking grapefruit while taking amlodipine. Also, avoid alcohol consumption, quit smoking, and limit salt intake (Aim for no more than 6g of salt a day).

If oedema occurs while taking amlodipine, stop using it and consult your healthcare provider right away.

Drinking alcohol can make amlodipine lower your blood pressure more than you need. This can make you sleepy or dizzy or bring on a headache.

SAMLOKIND 2.5MG TABLET can make some people feel dizzy. If this happens to you, do not drive a car, ride a bike, or use tools or machinery until you feel better.

SAMLOKIND 2.5MG TABLET contains S-amlodipine, a calcium channel blocker.

SAMLOKIND 2.5MG TABLET is generally safe to take for a long time. In fact, it works best when you take it for a long time.

SAMLOKIND 2.5MG TABLET can be given safely to children aged 6-12 years, provided a child specialist has prescribed the dose. SAMLOKIND 2.5MG TABLET should only be given to the children by consulting a child specialist.

SAMLOKIND 2.5MG TABLET is not recommended for use in pregnant women unless necessary. All the risks and benefits should be discussed with the doctor before taking SAMLOKIND 2.5MG TABLET.

Avoid exceeding the recommended dose, as it could lead to an overdose. Symptoms of overdose may include excessive peripheral vasodilation with marked low blood pressure and reflex tachycardia. If you experience these symptoms or suspect you have taken an overdose, seek immediate medical attention.

Country of origin

India

Manufacturer/Marketer address

208, Okhla Industrial Estate, Phase III, New Delhi - 110020
Other Info - SAM0015

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Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 18, 2025 | 6:49 AM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Reference

  1. https://www.medicines.org.uk/emc/files/pil.2743.pdf
  2. https://www.drugs.com/amlodipine.html
  3. https://www.nhs.uk/medicines/amlodipine/
  4. https://www.rxlist.com/consumer_amlodipine_norvasc/drugs-condition.htm#what_are_warnings_and_precautions_for_amlodipine

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