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compositionComposition:SAFINAMIDE-100MG
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Safiron 100mg Tablet is used in the treatment of Parkinson’s disease to help manage symptoms such as stiffness, tremors, and difficulty in movement. It helps improve motor control and supports smoother body movements, thereby enhancing daily functioning and quality of life in patients with Parkinson’s disease.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

SAFINAMIDE-100MG

Manufacturer/Marketer :

Intas Pharmaceuticals Ltd

Consume Type :

Oral

Expires on or after :

Dec-28

Return Policy :

Not Returnable

About Safiron 100mg Tablet

Safiron 100mg Tablet is an oral prescription medication used to treat Parkinson's disease. Specifically, it is prescribed as an add-on treatment for people who are already taking levodopa and carbidopa and are experiencing off episodes, which are periods when their regular medication wears off, and symptoms return.

To get the best results, you must take Safiron 100mg Tablet consistently at the same time every single day. You can take this medication with or without food, depending on your preference. Making certain lifestyle changes, such as eating a balanced diet, staying active, and participating in physical therapy, can also support your overall physical function and mobility.

While taking Safiron 100mg Tablet, some people may experience mild side effects like nausea or trouble sleeping. However, you must contact your doctor immediately if you notice serious symptoms, such as severe uncontrolled muscle movements, changes in your vision, or sudden, severe headaches.

Talk to your doctor before starting Safiron 100mg Tablet if you have liver problems, as this condition can affect how your body clears the medicine. Do not take this if you have severe liver damage, or if you are currently taking other monoamine oxidase inhibitors or certain antidepressants.

This medicine can interact with other drugs, including over-the-counter cough medicines and strong pain relievers, which can cause dangerous increases in blood pressure. Avoid drinking alcohol while taking this medicine, and consult your doctor if you are pregnant, planning to become pregnant, breastfeeding, or if you are an elderly individual.

Uses of Safiron 100mg Tablet

Safiron 100mg Tablet used in the treatment of Parkinson's disease. The detailed uses of Safiron 100mg Tablet are as follows:

  • Parkinson's disease: Safiron 100mg Tablet helps by extending the active time of your primary Parkinson's medications, reducing the daily periods when your movement symptoms return or worsen.
  • Movement control difficulties: It helps manage motor symptoms such as tremors, stiffness, and slowness of movement by stabilising chemical levels in the brain.

Key Benefits

Safiron 100mg Tablet helps improve movement in people with Parkinson's disease by reducing periods when symptoms return between doses of their regular medication.

The following are the benefits of Safiron 100mg Tablet:

  • Helps reduce 'off' periods between Parkinson's medication doses.
  • Increases the amount of time with better symptom control.
  • Improves movement and the ability to perform daily activities.
  • Reduces stiffness and movement difficulties.
  • Supports smoother control of Parkinson's symptoms throughout the day.
  • Promotes greater independence and overall quality of life.

Directions for Use

  • Safiron 100mg Tablet can be taken with or without food, but it is best to take it at the same time every day to establish a consistent routine.
  • Swallow Safiron 100mg Tablet as a whole with a glass of water.
  • Do not crush, chew, or break it.
  • Always follow your doctor's exact instructions regarding how to take this medicine, and do not change your dose or stop taking it without consulting them first.

How Safiron 100mg Tablet Works

Safiron 100mg Tablet contains safinamide, which works by helping your brain maintain higher, more consistent levels of dopamine, which is a natural chemical messenger responsible for controlling smooth and coordinated muscle movements. In Parkinson's disease, the brain lacks a sufficient amount of this chemical. This medicine works by blocking a specific enzyme in the brain called monoamine oxidase type B (MAO-B). This enzyme is normally responsible for breaking down dopamine. By stopping this breakdown process, Safiron 100mg Tablet allows the dopamine produced by your other Parkinson's medications to last longer and work more effectively in your body. It also helps regulate other overactive chemical signals in the brain, helping to steady your movements.
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Alcohol

Caution

Safiron 100mg Tablet may cause excessive drowsiness with alcohol, decreasing alertness and affecting your vision.

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Pregnancy

Unsafe

Safiron 100mg Tablet may be unsafe to use during pregnancy. Your doctor will weigh the benefits and potential risks before prescribing Safiron 100mg Tablet. Please consult your doctor before taking Safiron 100mg Tablet.

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Breast Feeding

Unsafe

Safiron 100mg Tablet may be unsafe to use in breastfeeding mothers. Your doctor will weigh the benefits and potential risks before prescribing Safiron 100mg Tablet. Please consult your doctor before taking Safiron 100mg Tablet.

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Driving

Caution

Safiron 100mg Tablet may decrease alertness, affect your vision or make you sleepy and dizzy. Do not drive if these symptoms occur.

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Liver

Caution

Safiron 100mg Tablet should be used with caution in patients with liver disease. A dose adjustment of Safiron 100mg Tablet may be needed. So please consult your doctor before taking Safiron 100mg Tablet.

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Kidney

Caution

Safiron 100mg Tablet should be used with caution in patients with kidney disease. A dose adjustment of Safiron 100mg Tablet may be needed. So please consult your doctor before taking Safiron 100mg Tablet.

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Children

Unsafe

Safiron 100mg Tablet is not recommended for use in children under 12 years.

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Heart

Caution

Safiron 100mg Tablet should be used with extreme caution due to the risk of cardiovascular problems. Please inform your physician if you have any concerns.

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Geriatrics

Safe if prescribed

Safiron 100mg Tablet is safe for use in elderly patients if prescribed by the physician.

What if I have taken an overdose of Safiron 100mg Tablet

If you suspect an overdose or have taken more than your prescribed dose, seek immediate medical attention or contact your local emergency services right away.

Diet & Lifestyle Advise

  • Watch your protein intake timing: High-protein meals (such as meat, dairy, or fish) can interfere with how your body absorbs your primary Parkinson's medication. Try to space out high-protein foods, so you do not eat them at the same time you take your dose.
  • Be cautious with tyramine-rich foods: Consuming very large amounts of foods high in tyramine (such as aged cheeses, air-dried or cured meats, and red wine) can sometimes affect your blood pressure. Speak with your doctor about whether you need to limit these items.
  • Prevent falls: Because Parkinson's disease and its treatments can cause dizziness when standing up, always rise slowly from sitting or lying positions, and keep your walkways clear of clutter.
  • Stay hydrated: Drink plenty of water throughout the day to help manage dry mouth, support digestion, and prevent sudden drops in blood pressure when you stand up.
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How Soon It Starts Working

  • The time required for Safiron 100mg Tablet to start to work: Safiron 100mg Tablet ideally shows its action within 2 to 3 hours after administration.
  • The time for which the effects of Safiron 100mg Tablet last: The effect of Safiron 100mg Tablet lasts for 24 hours.

What if you forget to take Safiron 100mg Tablet

If you miss a dose of Safiron 100mg Tablet, skip the missed dose and take your next scheduled dose the following day at your usual time. Do not take two doses at the same time to make up for a missed one.

Storage

• Store in a cool and dry place away from sunlight.• Keep Safiron 100mg Tablet out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Drug Warnings

  • Check your blood pressure regularly: Because this medication can influence your blood pressure, keep a home log of your readings and report any sudden, high spikes to your healthcare team.
  • Avoid driving if you feel excessively sleepy: If you experience severe daytime drowsiness or find yourself falling asleep suddenly during normal activities, do not drive or operate machinery, and inform your doctor immediately.
  • Monitor for eye health changes: If you have a history of retinal disease or experience any sudden changes in your vision, schedule an eye exam promptly.
  • Watch for new involuntary movements: Report any new or worsening muscle spasms or twitching to your doctor, as your other Parkinson's medications may need to be adjusted.
  • Do not stop taking this medicine suddenly: Abruptly stopping Safiron 100mg Tablet can cause your Parkinson's symptoms to return severely. Always talk to your doctor before making any changes.

verifiedApollotooltip
  • Antidepressants and monoamine oxidase inhibitors (MAOIs) (e.g., sertraline, amitriptyline, phenelzine): Taking Safiron 100mg Tablet with other MAO inhibitors or certain antidepressants can cause a life-threatening buildup of serotonin or a severe spike in blood pressure.
  • Cough and pain medications (e.g., dextromethorphan, tramadol): Combining Safiron 100mg Tablet with cough medicines or strong pain relievers can increase the risk of serious neurological side effects.

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verifiedApollotooltip
  • Tyramine-rich foods: Eating foods with very high levels of tyramine, such as aged cheeses, cured meats, sauerkraut, or tap beers, can interact with this medicine and cause a dangerous increase in blood pressure.

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTIPARKINSON AGENTS]

FAQs

Safiron 100mg Tablet is used to treat the signs and symptoms of Parkinson's disease.
Safiron 100mg Tablet works by increasing the amount of dopamine (a natural substance needed to control movement) in the brain. Thereby improving the symptoms of Parkinson's disease.
Yes, Safiron 100mg Tablet is not recommended in albinism (an inherited condition that causes a lack of colour in the skin, hair and eyes), retinal degeneration, uveitis (inflammation of the middle layer of the eye (uvea)), inherited retinopathy or severe progressive diabetic retinopathy.
Do not stop Safiron 100mg Tablet suddenly; it may cause side effects like confusion, stiff muscles and a high fever. So please consult your doctor before stopping the medicine.
The time it takes for Safiron 100mg Tablet to work can vary depending on the specific medication mechanism and the individual's health condition status.
In some individuals, Safiron 100mg Tablet may cause common side effects like cough, depression, indigestion, flu-like symptoms, insomnia (difficulty sleeping), joint pain, and peripheral oedema. Most of these side effects do not require medical attention and gradually resolve over time. However, if any persists or worsens, please consult your doctor.
Safiron 100mg Tablet can be taken with a glass of water. Do not chew, break, or crush it. Follow your doctor's instructions regarding dose and duration and complete the entire course as prescribed.
Safiron 100mg Tablet belongs to pregnancy category C, which means that animal studies have shown potential risks to the fetus, but there are no good studies in pregnant women. As a result, the medication should only be used during pregnancy if the potential benefits justify the possible risks. Always consult your healthcare provider for personalized guidance.
You can take Safiron 100mg Tablet with or without food. However, it is important to be consistent and take it at the same time each day. Talk to your doctor or pharmacist if you have questions about how to take it.
You should avoid drinking alcohol while taking Safiron 100mg Tablet, as alcohol can increase your risk of experiencing side effects like extreme drowsiness, dizziness, and unpredictable blood pressure changes. Talk to your doctor for specific guidance.
Feeling dizzy or lightheaded when standing is common with Parkinson's treatments. Try to stand up very slowly from a sitting or lying position, and make sure you are drinking enough fluids throughout the day. If the dizziness is severe or does not improve, talk to your doctor.
Yes, especially if it is taken with certain interacting medications or foods extremely high in tyramine. Monitor your blood pressure regularly at home and report any sudden spikes or severe headaches to your healthcare provider immediately. Talk to your doctor for more details.
No, Safiron 100mg Tablet does not cure Parkinson's disease. Instead, it helps manage and control your symptoms, specifically by reducing "off" times and helping you move more easily when used alongside other treatments. Talk to your doctor about your long-term treatment plan.
If you see, hear, or feel things that are not there, or experience unusual changes in your behaviour or thinking, seek medical advice immediately. Do not stop taking your medication abruptly, but talk to your doctor right away for guidance.

Disclaimer

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Country of origin

India
Other Info - SA35475
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