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  3. S-Hizide Tab

S-Hizide Tab, Pack of 30 CapsuleS
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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

S-Hizide Tab is used to treat liver disease, depression, and osteoarthritis. It works by protecting the liver from toxins, regulating mood and stimulating the production of cartilage. In some cases, this medicine may cause side effects such as headache, vomiting, diarrhoea, and dizziness. Before taking this medicine, inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Synonym :

S ADENOSYL L METHIONINE

Composition :

ADEMETIONINE-100MCG

Manufacturer/Marketer :

Ark Life Science Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About S-Hizide Tab

S-Hizide Tab is used in the treatment of depression, biliary cholangitis (an autoimmune disease of the liver), liver diseases caused by cystic fibrosis, and to reduce pain and swelling in the joints. It is also used to treat liver disease during pregnancy and improve symptoms in people with fibromyalgia.

S-Hizide Tab contains Ademetionine, a naturally occurring substance, produced from methionine (amino acid). S-Hizide Tab ensures sufficient levels of glutathione in the liver are maintained to minimize liver damage. It stimulates the production of cartilage, reduces inflammatory mediators, and has analgesic properties.

In some cases, you may experience common side effects such as abdominal discomfort, abdominal pain, diarrhoea, nausea, dizziness, and insomnia. Most of these side effects do not require medical attention and will resolve gradually over time. However, talk to your doctor if these side effects persist.

Take S-Hizide Tab as recommended by your doctor. It should be taken with a meal for better absorption. Your doctor will decide the dose and duration of medicine based on the type of condition. Do not chew, crush, or break the medicine.

Avoid taking S-Hizide Tab if you are allergic to it. Do not discontinue S-Hizide Tab without consulting your doctor. Consult the doctor if you are pregnant or breastfeeding. S-Hizide Tab can be given to children with extreme caution if recommended by the doctor. Avoid consuming alcohol with S-Hizide Tab as it could lead to increased drowsiness and liver damage. Keep your doctor informed about your health condition and medicines to rule out any side effects.

Uses of S-Hizide Tab

S-Hizide Tab is used for the treatment of depression, primary biliary cholangitis, and osteoarthritis. The detailed uses of S-Hizide Tab are as follows:

  • Depression & Mood Disorders: S-Hizide Tab helps regulate neurotransmitters like serotonin and dopamine and treat depression & mood disorders.
  • Arthritis Management: S-Hizide Tab helps to manage arthritis by reducing inflammation and pain, improving joint function and mobility in conditions like rheumatoid arthritis and osteoarthritis.
  • Treatment for Cholestasis: S-Hizide Tab is frequently recommended to treat pregnancy-related cholestasis, a disorder marked by decreased bile flow that usually results in elevated blood bile acids.
  • Promote Liver Function: S-Hizide Tab may be used to enhance bile production and promote liver function, which will help with fat digestion.
  • Liver Diseases: To improve liver function, S-Hizide Tab is occasionally included in treatment plans for a number of liver disorders, including fatty liver disease.



 

Directions for Use

  • S-Hizide Tab should be taken before a meal, as food may affect its absorption.
  • It is recommended to take S-Hizide Tab once daily or as advised by your doctor.
  • Swallow the whole S-Hizide Tab with a glass of water.
  • Do not crush, chew, or break it.

Medicinal Benefits

  • S-Hizide Tab contains Ademetionine, a naturally occurring substance in cells, tissue, and body fluids.
  • In liver disease, S-Hizide Tab ensures sufficient glutathione levels in the liver to minimize liver damage.
  • It prevents the increase of lipids associated with cirrhosis outside the liver. 
  • In depression, it affects certain chemical messengers (serotonin) in the brain, which communicate between brain cells, thereby regulating mood and treating depression.
  • In osteoarthritis, it stimulates the production of cartilage components, reduces inflammatory mediators, and has analgesic properties. S-Hizide Tab is also effective in treating nerve problems in people with AIDS, or sexual dysfunction in men with depression.

How S-Hizide Tab Works

S-Hizide Tab contains Ademetionine, a naturally occurring substance found in cells, tissue, and body fluids. It is produced from methionine (amino acid) and is used to treat liver disease, depression, and osteoarthritis. S-Hizide Tab ensures sufficient levels of glutathione in the liver are maintained to minimize liver damage. It also prevents the increase of lipids associated with cirrhosis outside the liver. It also affects certain chemical messengers (serotonin) in the brain, which communicate between brain cells, regulating mood and treating depression. It stimulates the production of parts of cartilage, reduces the inflammatory mediator, and has painkilling properties.

Storage

• Store in a cool and dry place away from sunlight.• Keep S-Hizide Tab out of the sight and reach of children.• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

What if I have taken an overdose of S-Hizide Tab

Take S-Hizide Tab only as prescribed by the physician. Do not exceed the recommended dose, as it might cause an overdose. If you suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

  • Do not take S-Hizide Tab if you are allergic to any of its contents
  • Do not use S-Hizide Tab if you have used an MAO inhibitor (antidepressant) in the past 14 days, as a dangerous drug interaction could occur.
  • Let your doctor know if you have any conditions like inflammation of gall bladder and bile ducts, narrowing or blockage of bile ducts, biliary colic, calcified gallstones, improper constriction of the gallbladder, gastric or duodenal ulcer, heart disease, seizure disorders, bone marrow suppression, diabetes, schizophrenia, bipolar disorder, acute alcohol intoxication, glaucoma, thyroid problems, or kidney and liver problems.
  • Do not take S-Hizide Tab if you are pregnant or breastfeeding unless advised by your doctor.
  • S-Hizide Tab can be given to children with caution if recommended by the doctor.
  • Avoid consuming alcohol along with S-Hizide Tab as it could lead to increased drowsiness and liver damage.
  • Keep your doctor informed about your health condition and medicines to rule out any unpleasant side effects.
  • Your doctor may advise a regular liver function test to monitor the liver's function and the treatment progress.

Diet & Lifestyle Advise

Liver disease:

  • Include foods such as bell peppers, citrus fruits, leafy vegetables, tomatoes, milk, fish, low-fat dairy, beans, nuts, lentils, tofu, and tempeh in your diet.
  • Foods rich in vitamins B and C and calcium are good for the gallbladder.
  • Plant-based protein foods such as beans, nuts, lentils, tofu, and tempeh help prevent gallbladder disease.
  • Avoid high-fat, trans-fat, processed foods, white bread, white pasta, and sugars.
  • Avoid tobacco and alcohol consumption.

Depression:

  • Maintaining a healthy diet and regular exercise helps improve overall health and boost self-esteem.
  • Perform meditation and yoga. This helps in relieving stress and provides relaxation.
  • Follow a regular sleep pattern to improve the amount and quality of sleep you get.
  • Include foods rich in omega fatty acids such as fish, nuts, fresh fruits, vegetables, and olive oils.
  • Neurotransmitters are made up of amino acids. Amino acid-rich foods such as meat, dairy products, and certain fruits and vegetables help properly maintain neurotransmitters. 
  • Avoid smoking and alcohol consumption.

Osteoarthritis:

  • Physical activity helps strengthen muscles and relieves joint stiffness. Gentle activities like 20-30 minutes of walking or swimming would be helpful.
  • Performing yoga may also help in improving joint flexibility and pain management.
  • Follow heat or cold therapy, and apply a cold or hot compress on the joints for 15-20 minutes regularly.

Habit Forming

No

Therapeutic Class

NUTRITIONAL SUPPLEMENT

S-Hizide Tab Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Unsafe

Avoid consumption of alcohol while taking S-Hizide Tab as it may cause increased dizziness and liver damage.

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Pregnancy

Consult your doctor

Avoid taking S-Hizide Tab if you are pregnant unless advised by a doctor. Please consult your doctor if you have any concerns regarding this, your doctor will recommend only if the benefits outweigh the risks.

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Breast Feeding

Consult your doctor

Consult your doctor before taking S-Hizide Tab, your doctor will decide whether S-Hizide Tab can be taken by breastfeeding mothers or not.

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Driving

Safe if prescribed

S-Hizide Tab does not affect your ability to drive. However, you are advised to be cautious while driving if you experience dizziness.

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Liver

Consult your doctor

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Consult your doctor

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Caution

S-Hizide Tab can be given to children with caution only if recommended by the doctor.

Have a query?

FAQs

S-Hizide Tab is used to treat various medical conditions, including depression, osteoarthritis, biliary cholangitis (an autoimmune disease of the liver), and excess cholesterol in bile and biliary and liver diseases caused by cystic fibrosis. It is also used to treat liver disease during pregnancy, improve symptoms in people with fibromyalgia, and treat nerve problems in people with AIDS or sexual dysfunction in men with depression.

S-Hizide Tab contains Ademetionine is used in the treatment of liver disease, depression, and osteoarthritis. It is used in liver conditions associated with reduced bile formation (intrahepatic cholestasis). It restores the balance of serotonin, a natural chemical present in the brain. It also blocks the production of certain inflammatory chemical substances that cause pain and swelling in osteoarthritis.

If you miss a dose, take it as soon as you remember. However, if it is time for the next scheduled dose, skip the missed dose and follow your usual dosage.

Do not discontinue S-Hizide Tab without consulting your doctor. To treat your condition effectively, continue taking S-Hizide Tab for as long as advised. Do not be reluctant to speak with your doctor if you feel any difficulty while taking S-Hizide Tab.

Do not take S-Hizide Tab if you have used MAO inhibitors (like isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, tranylcypromine, and others) in the last 14 days as the co-administration of S-Hizide Tab and MAO inhibitor cause serious drug interaction. Let know doctor know about this.

No, the S-Hizide Tab does not cure arthritis. S-Hizide Tab is only used to relieve symptoms of arthritis, such as joint pain, swelling and stiffness.

Yes, S-Hizide Tab is good for the liver. It aids liver function, minimises liver damage and treats liver disease.

S-Hizide Tab contains Ademetionine, a naturally occurring substance found in cells, tissue, and body fluids. It is produced from methionine (amino acid).

Do not take S-Hizide Tab if you are allergic to any of its components, if you have used an MAO inhibitor in the past 14 days, or if you have inflammation of gall bladder and bile ducts, narrowing or blockage of bile ducts, biliary colic, calcified gallstones, improper constriction of the gallbladder, gastric or duodenal ulcer.

S-Hizide Tab may cause side effects such as abdominal discomfort, abdominal pain, diarrhoea, nausea, dizziness, and insomnia. Talk to your doctor if you experience these side effects persistently.

It is not known if S-Hizide Tab is safe to use for the long term. Take S-Hizide Tab for the duration prescribed by the doctor.

Country of origin

India

Manufacturer/Marketer address

# 50/1 & 2-IIIrd Floor,Yusuf Sarai, New Delhi -110016 (India)
Other Info - SHI0065

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Author Details

Santoshini Reddy GDoctor badge

Written By

Santoshini Reddy G

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Aug 8, 2025 | 11:24 AM IST

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Reference

  1. https://www.drugs.com/mtm/s-adenosylmethionine-same.html
  2. https://www.webmd.com/vitamins/ai/ingredientmono-786/same

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