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  3. Rzole-20 Tablet 10's

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Rzole-20 Tablet 10's, Pack of 10 TABLETS
Rzole-20 Tablet 10's, Pack of 10 TABLETS
Rzole-20 Tablet 10's, Pack of 10 TABLETS
Rzole-20 Tablet 10's, Pack of 10 TABLETS
Rzole-20 Tablet 10's, Pack of 10 TABLETS
Rzole-20 Tablet 10's, Pack of 10 TABLETS
Rzole-20 Tablet 10's, Pack of 10 TABLETS
Rzole-20 Tablet 10's, Pack of 10 TABLETS
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Synonym :

RABEPRAZOLE SODIUM

Composition :

RABEPRAZOLE-20MG

Manufacturer/Marketer :

Mano Pharma

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Rzole-20 Tablet

Rzole-20 Tablet belongs to a group of medicines called proton pump inhibitors, which are used to reduce the amount of acid produced in the stomach. It is commonly prescribed to treat duodenal ulcers (sores in the upper part of the small intestine), gastro-oesophageal reflux disease or GERD (when stomach acid flows back into the food pipe), heartburn (a burning feeling in the chest caused by acid), and erosive oesophagitis (damage to the lining of the food pipe due to acid). It is also used to treat infections caused by a stomach bacteria called Helicobacter pylori (along with antibiotics), and a rare condition called Zollinger-Ellison syndrome (when the stomach makes too much acid).

Rzole-20 Tablet contains Rabeprazole, which works by blocking the acid-producing pumps in the stomach. By reducing acid levels, it helps relieve symptoms, allows ulcers and damaged areas to heal, and prevents new ulcers from forming.

Your doctor will decide the correct dose and duration depending on your condition, so it’s essential to follow their instructions carefully. Some people may experience side effects while taking Rzole-20 Tablet . Common ones include headache, dizziness, diarrhoea, constipation, nausea, vomiting, gas (bloating), weakness, or a runny nose. These are usually mild and go away on their own. However, if any of these symptoms continue or become bothersome, you should contact your doctor.

Before taking Rzole-20 Tablet , inform your doctor if you have any liver problems or a stomach tumour. Long-term use may lower magnesium and vitamin B12 levels, and slightly increase the risk of bone fractures. Avoid alcohol, as it can increase stomach acid and side effects like drowsiness. Additionally, this medication may cause drowsiness or dizziness, so avoid driving or operating machinery until you feel fully alert. Rzole-20 Tablet is not recommended for children, and if you are pregnant or breastfeeding, consult your doctor before using it.

Side Effects of Rzole-20 Tablet

  • Headache
  • Dizziness
  • Diarrhoea
  • Constipation
  • Nausea
  • Vomiting
  • Flatulence (wind)
  • Weakness

Uses of Rzole-20 Tablet

Rzole-20 Tablet is used to treat the following conditions:

  • Gastro-oesophageal Reflux Disease (GERD): Relieves heartburn and acid reflux by reducing stomach acid.
  • Erosive Oesophagitis: Heals damage to the food pipe caused by excess stomach acid.
  • Duodenal Ulcers: Helps heal sores in the upper part of the small intestine.
  • Gastric Ulcers: Treats and heals ulcers in the stomach lining.
  • Helicobacter pylori Infection (with antibiotics): Helps eliminate bacteria that cause ulcers.
  • Zollinger-Ellison Syndrome: Controls excessive acid production in the stomach.

Directions for Use

  • Rzole-20 Tablet can be taken with or without food depending on the medical condition. However, it is preferable to take it at least 30 minutes before a meal for better efficacy.
  • It is usually taken 1-2 times daily or as prescribed by your doctor.
  • Swallow Rzole-20 Tablet as a whole with a glass of water.
  • Do not crush or chew this medication.

Key Benefits

  • Rzole-20 Tablet contains Rabeprazole, a proton pump inhibitor (PPI) used to treat conditions caused by excess stomach acid.
  • It is commonly prescribed to manage acid-related disorders such as gastric and duodenal ulcers, acid reflux, and GERD (gastro-oesophageal reflux disease).
  • Rabeprazole works by blocking proton pumps in the stomach lining, which are responsible for producing acid.
  • By reducing acid levels, Rzole-20 Tablet helps relieve symptoms like heartburn, indigestion, and sour burps.
  • It also promotes the healing of ulcers and acid-related damage in the oesophagus (food pipe).
  • When taken as prescribed, Rzole-20 Tablet helps prevent the recurrence of ulcers and effectively manages chronic conditions such as GERD and Zollinger-Ellison syndrome.
  • Maintaining a healthy diet, avoiding spicy or acidic foods, reducing stress, quitting smoking, and limiting alcohol can improve the effectiveness of Rzole-20 Tablet and support better digestive health over time.

How Rzole-20 Tablet Works

Rzole-20 Tablet contains 'Rabeprazole' that works by blocking the action of the enzyme known as gastric proton pump which is responsible for the production of acid. This helps in reducing the amount of acid produced, heals the ulcers and prevents the formation of new ulcers.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Rzole-20 Tablet
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Here are the steps to cope with constipation as a side effect of medication:
  • Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
  • Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
  • Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
  • Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
  • Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
  • Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Here are the steps to manage Gastrointestinal Air and Swelling (GAS) caused by medication:
  • Tell your doctor about your GAS symptoms. They may change your medication regimen or prescribe additional drugs to help you manage them.
  • To manage GAS symptoms, eat a balanced diet of fibre, vegetables, and fruits.
  • Drink enough water throughout the day to avoid constipation and treat GAS symptoms.
  • Regular exercise like yoga and walking may help stimulate digestion and alleviate GAS symptoms.
  • Take probiotics only if your doctor advises, as they may help alleviate GAS symptoms by promoting gut health.
  • Take medication for GAS symptoms only if your doctor advises, as certain medications can interact with your existing prescriptions or worsen symptoms.
  • If symptoms persist, worsen, or are accompanied by severe abdominal pain, vomiting, or bleeding, seek immediate medical attention.
  • Apply a hot/cold pack to the affected area.
  • Doing gentle exercises can help cope with pain by stretching muscles.
  • Get enough sleep. It helps enhance mood and lower pain sensitivity.
  • Avoid alcohol, smoking and tobacco as they can increase pain.
  • Follow a well-balanced meal.
  • Meditation and massages may also help with pain.
  • Drink warm fluids such as warm water with honey, broth, soup or herbal tea to soothe sore throat.
  • Gargle with warm salt water.
  • Suck on lozenges to increase the production of saliva and soothe your throat.
  • Use a humidifier to soothe sore throat as it adds moisture to the air and makes breathing easier.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.

What if I have taken an overdose of Rzole-20 Tablet

Do not take more than the prescribed dose. Using more medication will not improve your symptoms; rather, they may cause poisoning or serious side effects. If you suspect that you may have overdosed of Rzole-20 Tablet or if you experience any adverse events, please go to the emergency department of the closest hospital.

Drug Warnings

  • Do not take Rzole-20 Tablet if you are allergic to Rabeprazole or any of its ingredients.
  • Inform your doctor if you have liver problems, gastrointestinal conditions, or are scheduled for specific lab tests (e.g., Chromogranin A), as Rabeprazole may affect results.
  • Consult your doctor if you are pregnant, planning to become pregnant, or breastfeeding, before starting Rzole-20 Tablet .
  • Seek medical attention if you experience symptoms such as severe abdominal pain, persistent diarrhoea, dizziness, muscle cramps, or signs of low magnesium or vitamin B12 deficiency.
  • Let your doctor know about all other medications you are taking, including over-the-counter drugs, herbal products, or supplements, to avoid interactions.
  • Use in children is not recommended, as the safety and effectiveness of Rzole-20 Tablet have not been established in pediatric patients.
  • Elderly patients (65 years and above) should use Rzole-20 Tablet with caution, as they may be at greater risk for side effects like low magnesium levels, vitamin B12 deficiency, and bone fractures with long-term use.

Drug-Drug Interactions

verifiedApollotooltip
RabeprazoleErlotinib
Critical
RabeprazoleRilpivirine
Critical

Drug-Drug Interactions

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RabeprazoleErlotinib
Critical
How does the drug interact with Rzole-20 Tablet:
When used in combination with erlotinib, Rzole-20 Tablet may prevent the absorption of erlotinib into the circulation, which might make erlotinib less effective in treating cancer.

How to manage the interaction:
Taking Rzole-20 Tablet with Erlotinib is not recommended as it can result in an interaction, it should be taken only if a doctor has advised it. Do not stop using any medications without consulting a doctor.
RabeprazoleRilpivirine
Critical
How does the drug interact with Rzole-20 Tablet:
Co-administration of Rzole-20 Tablet can make Rilpivirine less effective by reducing its absorption in the body.

How to manage the interaction:
Taking Rzole-20 Tablet with Rilpivirine is not recommended, but can be taken if prescribed by the doctor. Do not discontinue the medications without consulting a doctor.
RabeprazoleDasatinib
Severe
How does the drug interact with Rzole-20 Tablet:
Taking Rzole-20 Tablet together with Dasatinib results in decreased levels of Dasatinib and its effectiveness.

How to manage the interaction:
Although taking Rzole-20 Tablet and Dasatinib together can result in an interaction, it can be taken if a doctor has prescribed it. Do not discontinue any medications without a doctor's advice.
RabeprazoleIdelalisib
Severe
How does the drug interact with Rzole-20 Tablet:
When Rzole-20 Tablet and Idelalisib are taken in combination, Idelalisib may increase the level or impact of Rzole-20 Tablet.

How to manage the interaction:
Although taking Rzole-20 Tablet and Idelalisib together can result in an interaction, it can be taken if a doctor has prescribed it. Do not discontinue any medications without a doctor's advice.
RabeprazolePazopanib
Severe
How does the drug interact with Rzole-20 Tablet:
Taking Rzole-20 Tablet together with Pazopanib can result in a decreased effectiveness of Pazopanib in treating the disease.

How to manage the interaction:
Although taking Rzole-20 Tablet and Pazopanib together can result in an interaction, but can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without talking to a doctor.
RabeprazoleGefitinib
Severe
How does the drug interact with Rzole-20 Tablet:
Taking Rzole-20 Tablet together with Gefitinib results in decreased levels of gefitinib in your blood. This can result in a decreased effectiveness of gefitinib in treating the disease.

How to manage the interaction:
Although taking Rzole-20 Tablet and Gefitinib together can possibly result in an interaction, it can be taken if your doctor has prescribed it. To lessen the effects of the interaction, it is advised that you take gefitinib 12 hours before or 12 hours after Rzole-20 Tablet. Do not discontinue any medications without a doctor's advice.
RabeprazoleMethotrexate
Severe
How does the drug interact with Rzole-20 Tablet:
Co-administration of Methotrexate with Rzole-20 Tablet can increase the blood levels and side effects of Methotrexate.

How to manage the interaction:
Although there is a possible interaction between Rzole-20 Tablet and Methotrexate, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without consulting a doctor.
RabeprazoleClopidogrel
Severe
How does the drug interact with Rzole-20 Tablet:
Taking Clopidogrel with Rzole-20 Tablet can reduce the effectiveness of Clopidogrel.

How to manage the interaction:
Taking Clopidogrel and Rzole-20 Tablet together possibly has an interaction, but you can take these medications together if a doctor has advised it. Do not stop using any medications without talking to a doctor.
RabeprazoleAcalabrutinib
Severe
How does the drug interact with Rzole-20 Tablet:
Taking Rzole-20 Tablet together with Acalabrutinib results in a decreased effectiveness of Acalabrutinib.

How to manage the interaction:
Although taking Rzole-20 Tablet and Acalabrutinib together can result in an interaction, it can be taken if a doctor has prescribed it. Do not discontinue any medications without a doctor's advice.
RabeprazolePhenytoin
Severe
How does the drug interact with Rzole-20 Tablet:
When Phenytoin and Rzole-20 Tablet are taken in combination, Phenytoin will reduce the concentration or impact of Rzole-20 Tablet.

How to manage the interaction:
Although taking Phenytoin and Rzole-20 Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. Do not discontinue any medications without a doctor's advice.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat smaller meals more often.
  • Avoid smoking and alcohol consumption. Alcohol intake leads to increased production of stomach acid, thereby increasing acidity and heartburn.
  • Maintain a healthy weight by regular exercising.
  • Avoid lying down after eating to prevent acid reflux.
  • Avoid tight-fitting clothes as it might increase the pressure on the abdomen, leading to acid reflux.
  • Practise relaxation techniques and avoid stress by doing yoga or meditation.
  • Avoid foods such as high-fat, spicy food, chocolates, citrus fruits, pineapple, tomato, onion, garlic, tea, and soda.
  • Avoid sitting continuously, as it may trigger acidity. Take a 5-minute break every hour by brisk walking or stretching.

Habit Forming

No

Therapeutic Class

ANTIULCERS

Rzole-20 Tablet Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Unsafe

Avoid consumption of alcohol while taking Rzole-20 Tablet . Alcohol intake leads to increased production of stomach acid, thereby increasing acidity and heartburn.

bannner image

Pregnancy

Caution

Please consult your doctor if you are pregnant. Your doctor will weigh the benefits and any potential risks before prescribing Rzole-20 Tablet .

bannner image

Breast Feeding

Caution

Please consult your doctor if you are breastfeeding. Your doctor will decide if Rzole-20 Tablet can be taken by breastfeeding mothers or not.

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Driving

Caution

Rzole-20 Tablet may cause dizziness and sleepiness. Do not drive or operate machinery unless you are alert.

bannner image

Liver

Caution

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

bannner image

Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

bannner image

Children

Unsafe

Rzole-20 Tablet is not recommended for children as the safety and effectiveness were not established.

Have a query?

FAQs

Rzole-20 Tablet is used to treat duodenal ulcers, gastro-oesophageal reflux disease (reflux of gastric contents into the oesophagus), heartburn, erosive oesophagitis (acid-related damage to the lining of the oesophagus), infections caused by Helicobacter pylori when given along with an antibiotic, and Zollinger-Ellison syndrome.

Rzole-20 Tablet works by blocking the action of the enzyme known as gastric proton pump that is responsible for the production of acid. This helps in reducing the amount of acid produced, heals the ulcers and prevents the formation of new ulcers.

Talk to your doctor if you do not feel better even after taking Rzole-20 Tablet for 14 days. Do not take Rzole-20 Tablet for longer durations unless prescribed by the doctor. If Rzole-20 Tablet is prescribed for longer durations, a regular check-up is advised.

Do not discontinue Rzole-20 Tablet without consulting your doctor. To treat your condition effectually, continue taking Rzole-20 Tablet for as long as prescribed. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Rzole-20 Tablet .

Diarrhoea might be a side-effect of Rzole-20 Tablet . Drink lots of fluids and eat non-spicy food if you experience diarrhoea. If you find blood in stools (tarry stools) or if you experience severe diarrhoea, consult your doctor. Prolonged intake of Rzole-20 Tablet is linked with a greater risk of Clostridium difficile-associated diarrhoea, so if you develop diarrhoea that does not improve, immediately consult a doctor.

Dry mouth could be a side effect of Rzole-20 Tablet . Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly, and chewing sugar-free gum/candy might help stimulate saliva and thereby prevent dry mouth.

On long-term treatment, Rzole-20 Tablet might increase the risk of fractures of the hip, spine, and wrist. Inform your doctor if you have osteoporosis or if you are taking corticosteroids.

Rzole-20 Tablet should be used with caution in the elderly as it may cause bone weakness and increased risk of fractures if taken for longer duration.

Inform your doctor before taking Rzole-20 Tablet if you are due to have Chromogranin A blood test. Rzole-20 Tablet may cause abnormal blood and liver enzyme values. Inform the person doing the tests that you are taking Rzole-20 Tablet . This medicine may cause dizziness and sleepiness, so drive only if you are alert.

Long term treatment with Rzole-20 Tablet may cause malabsorption of vitamin B12 leading to its deficiency. Consult the doctor if you notice symptoms of cyanocobalamin deficiency like tiredness, sore mouth, mouth ulcers and pins & needles sensation.

Rzole-20 Tablet can be taken on an empty stomach as it helps regulate acid production.

Side effects of Rzole-20 Tablet include headache, dizziness, diarrhoea, constipation, nausea, vomiting, flatulence (wind), weakness, and runny nose. Consult the doctor if the side effects persist or worsen.

Country of origin

India

Manufacturer/Marketer address

No. 447, Poonamallee High Road, Aminjikarai, Chennai 600029.
Other Info - RZO0003

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Author Details

Santoshini Reddy GDoctor badge

Written By

Santoshini Reddy G

M Pharmacy

Bayyarapu Mahesh KumarDoctor badge

Reviewed By

Bayyarapu Mahesh Kumar

M Pharmacy

Last Updated

Aug 8, 2025 | 11:56 AM IST

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Reference

  1. https://www.medicines.org.uk/emc/files/pil.2842.pdf
  2. https://www.accessdata.fda.gov/drugsatfda_docs/label/2014/020973s035204736s005lbl.pdf
  3. https://www.nhs.uk/medicines/rabeprazole/
  4. https://www.drugs.com/mtm/rabeprazole.html

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