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  3. Ryso-Cort 30 Tablet

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Ryso-Cort 30 Tablet, Pack of 1 Tablet
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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Ryso-Cort 30 Tablet is used to treat Duchenne muscular dystrophy in adults and children above 2 years of age. It contains Deflazacort, which inhibits the production of chemicals called cytokines responsible for inflammation. Some people may experience side effects such as nausea, chest pain, vomiting, drowsiness, headache, dizziness, skin rash, tremors, nervousness, diarrhea and fast heartbeats. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Composition :

DEFLAZACORT-30MG

Manufacturer/Marketer :

Rybin Pharma

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Ryso-Cort 30 Tablet

Ryso-Cort 30 Tablet is used to treat autoimmune conditions like Duchenne muscular dystrophy in adults and children above 2 years of age. Autoimmune disease is a health disorder in which the immune system doesn't work normally and is unable to distinguish between foreign cells and native cells.

Ryso-Cort 30 Tablet is an immunosuppressive drug that binds to immune cells, resulting in the inhibition of inflammation and autoimmune diseases that occur due to the production of chemicals called cytokines, which are responsible for inflammation.

Some people may experience nausea, chest pain, vomiting, drowsiness, headaches, dizziness, skin rashes, tremors, nervousness, diarrhoea, and fast heartbeats. If the side effects persist or worsen, please consult your doctor.

Before starting Ryso-Cort 30 Tablet, please inform your doctor that you are allergic or hypersensitive to Ryso-Cort 30 Tablet. Extra care is needed when a patient has an existing infection being treated (systemic infection) or has recently received live virus vaccines. A doctor's consultation is required as Ryso-Cort 30 Tablet is not safe to use during pregnancy.

Uses of Ryso-Cort 30 Tablet

Ryso-Cort 30 Tablet used in the treatment of Duchenne muscular dystrophy (DMD). The detailed uses of Ryso-Cort 30 Tablet are as follows:

  • Treatment of DMD: Ryso-Cort 30 Tablet used to treat Duchenne muscular dystrophy by slowing muscle degeneration, preserving strength, and improving mobility.
  • Anti-Inflammatory Treatment: Ryso-Cort 30 Tablet helps reduce inflammation and alleviate symptoms associated with conditions such as arthritis, bursitis, and tendinitis.
  • Autoimmune Disorders Management: Ryso-Cort 30 Tablet helps to manage autoimmune diseases like lupus and multiple sclerosis by suppressing the immune response.
  • Relief from Allergic Reactions: Ryso-Cort 30 Tablet provides relief from symptoms of allergic reactions, such as allergic rhinitis, by reducing inflammation and immune response.
  • Managing Respiratory Conditions: Ryso-Cort 30 Tablet is also involved in managing respiratory conditions like asthma and COPD by reducing airway inflammation.
  • Skin Disorders Treatment: Ryso-Cort 30 Tablet treats skin conditions like eczema and psoriasis by reducing inflammatory responses.

Have a query?

Directions for Use

  • Ryso-Cort 30 Tablet can be taken with or without food.
  • It is usually taken once daily at the same time each day or as prescribed by your doctor.
  • Swallow Ryso-Cort 30 Tablet as a whole with a glass of water.
  • Do not crush or chew this medication.
  • If you cannot swallow the tablet as a whole, you may break it in half and take both halves separately.

Medicinal Benefits

  • Ryso-Cort 30 Tablet is used in the treatment of Duchenne muscular dystrophy (DMD).
  • It is beneficial in inflammatory diseases, including asthma, arthritis, and allergies.
  • It works by reducing the formation of inflammatory substances and suppressing the immune system's response to prevent self-damage (autoimmune reactions that occur in organ transplants, autoimmune diseases, or cancer).
  • Ryso-Cort 30 Tablet is a steroid that interacts with overactive immune cells, slowing their activity and decreasing the damaging effects they cause in the body.
  • Ryso-Cort 30 Tablet makes organ transplantation possible and treats muscle disorders like Duchenne muscular dystrophy.

How Ryso-Cort 30 Tablet Works

Ryso-Cort 30 Tablet is an immunosuppressive drug that works by binding to immune system cells and turns off the receptors that lead to their abnormal functioning or damaging effects. Ryso-Cort 30 Tablet binds to immune cells, resulting in the inhibition of inflammation and autoimmune diseases that occur due to the production of chemicals called cytokines, which are responsible for inflammation. Thus, Ryso-Cort 30 Tablet is beneficial in autoimmune diseases and inflammation that causes harm in various organs, especially in joints in arthritis, skin, and psoriasis. Ryso-Cort 30 Tablet makes organ transplantation possible, and treats muscle disorders like Duchenne muscular dystrophy.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Ryso-Cort 30 Tablet
  • Eat a balanced diet containing enough proteins, fibre, healthy fats, vegetables and fruits.
  • Get quality sleep for about 7-9 hours.
  • Try to manage stress with meditation or yoga.
  • Drink enough water.
  • Exercise regularly as it helps regulate appetite.
Here are the steps to manage the medication-triggered Upper respiratory tract infection:
  • Inform your doctor about the symptoms you're experiencing due to medication.
  • Your doctor may adjust your treatment plan, which could include changing your medication, adding new medications, or offering advice on managing your symptoms.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • Stay hydrated by drinking plenty of fluids to help loosen and clear mucus from your nose, throat, and airways.
  • Get plenty of rest and engage in stress-reducing activities to help your body recover. If your symptoms don't subside or worsen, consult your doctor for further guidance.
Here are the steps to manage the medication-triggered Cough:
  • Tell your doctor about the cough symptoms you're experiencing, which may be triggered by your medication.
  • Your doctor may adjust your treatment plan by changing your medication, adding new medications, or providing guidance on managing your cough symptoms.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • Stay hydrated by drinking plenty of fluids, such as water, tea, or soup, to help thin out mucus and soothe your throat.
  • Get plenty of rest and engage in stress-reducing activities to help your body recover. If your cough persists or worsens, consult your doctor for further guidance.
  • Drink six to eight glasses of water per day to be healthy.
  • Healthy urinary habits can help minimize pollakiuria (frequent urinating).
  • Avoid liquids containing caffeine, artificial sweeteners, and soda, as they might cause bladder discomfort.
  • Add bladder-friendly foods such as omega-3 fatty acids, blueberries, and cranberries.
Here are the steps to manage the medication-triggered Common Cold:
  • Inform your doctor about the common cold symptoms you're experiencing due to medication.
  • Your doctor may adjust your treatment plan, which could include changing your medication, adding new medications, or offering advice on managing your symptoms.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • Drink plenty of fluids, such as warm water or soup, to help thin out mucus.
  • Get plenty of rest and engage in stress-reducing activities to help your body recover. If your symptoms don't subside or worsen, consult your doctor for further guidance.
  • Regular cleansing will help get rid of dead skin cells and stop ingrown hairs.
  • Keep your hormones in balance by managing your stress, eating well and exercising regularly.
  • Shaving, waxing, and bleaching are ways to get rid of extra hair.

What if I have taken an overdose of Ryso-Cort 30 Tablet

Do not take more than the prescribed dose of Ryso-Cort 30 Tablet as it may cause severe side effects. If you suspect you have taken an overdose, please consult a doctor immediately.

Drug Warnings

  • Patients with a history of tuberculosis (TB), heart disease or heart failure stomach disorders (gastritis, peptic ulcer), diabetes (including family history), osteoporosis (bone disease), myasthenia gravis (muscle weakness), depression, mental distress, history of muscular problems caused by corticosteroids, kidney and liver dysfunction (including hepatic insufficiency and cirrhosis), should consult a doctor before using Ryso-Cort 30 Tablet. 
  • This medicine is not recommended for children less than 5 years of age, lactating mothers and pregnant women.
  • Avoid going near people who are sick or infected while using Ryso-Cort 30 Tablet. 
  • Before taking Ryso-Cort 30 Tablet and for at least 4-6 weeks, do not take any live vaccine, as it may cause severe allergic reactions.
  •  Do not quit taking deflazacort without consulting your physician. Symptoms such as loss of appetite, stomach upset, vomiting, drowsiness, confusion, headache, fever, joint and muscle pain, peeling skin, and weight loss may occur when the medication is stopped suddenly.

Drug-Drug Interactions

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DeflazacortDesmopressin
Critical
DeflazacortRifampicin
Severe

Drug-Drug Interactions

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DeflazacortDesmopressin
Critical
How does the drug interact with Ryso-Cort 30 Tablet:
Co-administration of Ryso-Cort 30 Tablet and Desmopressin may increase the risk of hyponatremia (low levels of salt in the blood).

How to manage the interaction:
Although co- administration of Daflazacort with Desmopression can possibly lead to an interaction, it can be taken in case a doctor advices you. You should seek medical attention if you experience loss of appetite, nausea, vomiting, headache, lethargy, irritability, difficulty in concentrating, memory impairment, confusion, muscle spasm, weakness, unsteadiness, decreased urination, or sudden weight gain. Do not stop using any medications without consulting a doctor.
DeflazacortRifampicin
Severe
How does the drug interact with Ryso-Cort 30 Tablet:
Taking Rifampicin with Ryso-Cort 30 Tablet may reduce the blood levels of Ryso-Cort 30 Tablet, which may make the medication less effective in treating the condition.

How to manage the interaction:
Although there is an interaction between Ryso-Cort 30 Tablet and rifampicin, they can be taken together if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.
DeflazacortNorfloxacin
Severe
How does the drug interact with Ryso-Cort 30 Tablet:
Norfloxacin can cause tendinitis (inflammation of the thick fibrous cords that attach muscle to bone) and tendon rupture (injury to the soft tissue that connect muscle to bone), and the risk may be increased when combined with other drugs such as Ryso-Cort 30 Tablet.

How to manage the interaction:
Although there is an interaction, Norfloxacin can be taken with Ryso-Cort 30 Tablet if prescribed by the doctor. However, if you experience pain, or swelling at the back of the ankle, biceps, shoulder, hand, or thumb, consult a doctor immediately. Avoid exercise or use of the affected area until further instruction from your doctor. Do not stop using any medications without talking to a doctor.
DeflazacortOfloxacin
Severe
How does the drug interact with Ryso-Cort 30 Tablet:
Co-administration Bempedoic acid and Ryso-Cort 30 Tablet can result in tendinitis (inflammation of the thick fibrous cords that connect muscle to bone) and tendon rupture.

How to manage the interaction:
Although taking Bempedoic acid and Ryso-Cort 30 Tablet together may cause an interaction, they can be taken if prescribed by a doctor. Consult a doctor if you have pain, swelling, or inflammation in a muscle location such as the back of the ankle, shoulder, or biceps. Do not discontinue any medications without consulting a doctor.
DeflazacortCarbamazepine
Severe
How does the drug interact with Ryso-Cort 30 Tablet:
Taking Carbamazepine with Ryso-Cort 30 Tablet may significantly reduce the blood levels of Ryso-Cort 30 Tablet, which may make the medication less effective in treating the condition.

How to manage the interaction:
Although using Carbamazepine and Ryso-Cort 30 Tablet together can possibly result in an interaction, they can be taken together if advised by your doctor. Do not stop taking any medications without consulting a doctor.
DeflazacortDabrafenib
Severe
How does the drug interact with Ryso-Cort 30 Tablet:
Co- administration of Dabrafenib with Ryso-Cort 30 Tablet may significantly reduce the blood levels of Ryso-Cort 30 Tablet, which may make the medication less effective in treating the condition.

How to manage the interaction:
Although using Dabrafenib and Ryso-Cort 30 Tablet together can possibly result in an interaction, they can be taken together if advised by your doctor. Do not stop taking any medications without consulting a doctor.
DeflazacortEfavirenz
Severe
How does the drug interact with Ryso-Cort 30 Tablet:
Taking Efavirenz with Ryso-Cort 30 Tablet may significantly reduce the blood levels of Ryso-Cort 30 Tablet, which may make the medication less effective in treating the condition.

How to manage the interaction:
Although using Efavirenz and Ryso-Cort 30 Tablet together can result in an interaction, they can be taken together if advised by your doctor. However, consult your doctor if your condition worsens. Do not stop taking any medications without consulting a doctor.
DeflazacortBempedoic acid
Severe
How does the drug interact with Ryso-Cort 30 Tablet:
Co-administration of Bempedoic acid and Ryso-Cort 30 Tablet can increase the risk of tissue injury near muscles and joints.

How to manage the interaction:
Although there is an interaction, Bempedoic acid can be taken with Ryso-Cort 30 Tablet if prescribed by the doctor. However, consult a doctor immediately if you experience pain or swelling in joints. Avoid exercise or use of the affected area. Do not stop using any medications without talking to a doctor.
DeflazacortAmprenavir
Severe
How does the drug interact with Ryso-Cort 30 Tablet:
Coadministration of Amprenavir with Ryso-Cort 30 Tablet can increase the levels of Ryso-Cort 30 Tablet in the body.

How to manage the interaction:
Taking Amprenavir with Ryso-Cort 30 Tablet together can result in an interaction. It can be taken if your doctor has advised it. However, if you experience symptoms like muscle weakness, excessive growth of facial or body hair, sudden dizziness, lightheadedness, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
DeflazacortFosphenytoin
Severe
How does the drug interact with Ryso-Cort 30 Tablet:
Taking Fosphenytoin with Ryso-Cort 30 Tablet may significantly reduce the blood levels of Ryso-Cort 30 Tablet, which may make the medication less effective in treating the condition.

How to manage the interaction:
Although using Fosphenytoin and Ryso-Cort 30 Tablet together can possibly result in an interaction, they can be taken together if advised by your doctor. Do not stop taking any medications without consulting a doctor.

Drug-Food Interactions

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DEFLAZACORT-30MGGrapefruit and Grapefruit Juice
Moderate

Drug-Food Interactions

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DEFLAZACORT-30MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit Juice, Grapefruit

How to manage the interaction:
Consuming grapefruit juice while on Ryso-Cort 30 Tablet therapy may elevate Ryso-Cort 30 Tablet levels in the bloodstream. Avoid or limit the consumption of grapefruit and grapefruit juice.

Diet & Lifestyle Advise

  • A patient needs to take extra care of their hygiene and stay away from places or people believed to be a cause of infection, as this drug affects the immune system. Therefore, proper care is necessary.
  • Maintain a healthy lifestyle by practising meditation and Yoga.
  • Eat fresh fruits, green leafy vegetables and dry fruits, etc.

Habit Forming

No

Therapeutic Class

ANTI- INFLAMMATORY AGENTS

All Substitutes & Brand Comparisons

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Alcohol

Caution

The effect of taking both alcohol and Ryso-Cort 30 Tablet may lead to bleeding and ulcers in the stomach. A doctor's consultation is recommended.

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Pregnancy

Unsafe

Not recommended in pregnant females. Ryso-Cort 30 Tablet crosses the placenta and increases the risk of fetal and neonatal damage.

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Breast Feeding

Consult your doctor

No adverse effect is reported, yet it is advised to have a doctor's consultation for breastfeeding mothers.

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Driving

Unsafe

A patient may experience muscle weakness/feel tired. Do not drive and do not use tools or machines while using this drug.

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Liver

Caution

If you've ever had hepatitis B or if you are a carrier of hepatitis B, using Ryso-Cort 30 Tablet can cause this virus to become active or get worse. You may need frequent liver function tests. If you need surgery, tell the surgeon ahead of time that you are using Ryso-Cort 30 Tablet.

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Kidney

Consult your doctor

Before using Ryso-Cort 30 Tablet, it is recommended to have a doctor's consultation. It may affect the kidneys in a few cases.

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Children

Unsafe

Ryso-Cort 30 Tablet is not recommended for children below 5 years of age. Children between 5-10 years of age should consult a doctor before using Ryso-Cort 30 Tablet.

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Heart

Caution

Ryso-Cort 30 Tablet can be used in heart patients if prescribed by the physician. Please consult your physician if you have any concerns.

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Geriatrics

Unsafe

Ryso-Cort 30 Tablet should be avoided in geriatric patients, as it can cause adverse effects like stroke, falls, or death in some patients.

FAQs

Ryso-Cort 30 Tablet is used to treat Duchenne muscular dystrophy. It may also be used to treat allergic and inflammatory disorders.

Not recommended for mild allergies. Ryso-Cort 30 Tablet is recommended only after consulting a doctor, as it is a strong medicine that produces considerable side effects, and is used only in moderate to severe cases.

It is not recommended to take Ryso-Cort 30 Tablet with alcohol as it may cause stomach bleeding.

No, it is not recommended to be used in seasonal allergy or mild cases. Only on a doctor's consultation, Ryso-Cort 30 Tablet may be used in extreme cases of seasonal allergy.

You should not use Ryso-Cort 30 Tablet if you have taken live vaccines of mumps, measles, rubella (MMR), polio, rotavirus, yellow fever, typhoid, nasal flu (influenza), varicella (chickenpox), and zoster (shingles). Do not take Ryso-Cort 30 Tablet if you have a compromised immune system, eye problems or weak bones.

Other Info - RYSO881

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Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Nov 21, 2025 | 11:20 AM IST

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Reference

  1. https://pubchem.ncbi.nlm.nih.gov/compound/Deflazacort
  2. https://www.medicines.org.uk/emc/files/pil.6287.pdf
  3. https://www.mims.com/india/drug/info/deflazacort?type=full&mtype=generic
  4. https://medlineplus.gov/druginfo/meds/a617024.html
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