Rucaven 300 mg Tablet 60's

Prescription drug

MRP ₹54000

(Inclusive of all Taxes)

₹8100.0 Cashback (15%)

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Written By Santoshini Reddy G , M Pharmacy

Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Rucaven 300 mg Tablet 60's is indicated in the treatment of ovarian, fallopian tube, and primary peritoneal cancer. It contains Rucaparib, which works by blocking an enzyme that repairs damaged DNA in cancer cells, resulting in their death. Thus, it kills cancer cells and helps treat cancer. In some cases, it may cause side effects such as fatigue, nausea, vomiting, diarrhoea, and decreased or loss of appetite.

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About Rucaven 300 mg Tablet 60's

Rucaven 300 mg Tablet 60's belongs to the group of anti-cancer medicines called PARP (poly adenosine diphosphate-ribose polymerase) indicated in the treatment of ovarian cancer, fallopian tube, and primary peritoneal cancer. It is also indicated in the treatment of prostate cancer that has spread to other areas in the body in people with a specific gene who have received other treatments.

Rucaven 300 mg Tablet 60's contains Rucaparib, which works by blocking an enzyme that repairs damaged DNA in cancer cells, resulting in their death. Thereby, it kills cancer cells and helps treat cancer.

In some cases, Rucaven 300 mg Tablet 60's may cause side effects such as fatigue, nausea, vomiting, diarrhoea, decreased or loss of appetite. Most of these side effects may not require medical attention and resolve gradually over time. However, if any of the side effects persist or worsen, inform your doctor.

Let the doctor know if you are allergic to any of the components in Rucaven 300 mg Tablet 60's. Rucaven 300 mg Tablet 60's is not recommended for use in children as the safety and effectiveness have not been established. Inform your doctor about your health condition and medications to rule out any side effects/interactions.

Uses of Rucaven 300 mg Tablet 60's

Rucaven 300 mg Tablet 60's used in the treatment of ovarian cancer, fallopian tube cancer, primary peritoneal cancer and prostate cancer. The detailed uses of Rucaven 300 mg Tablet 60's are as follows:

Treatment of Ovarian Cancer: Rucaven 300 mg Tablet 60's targets and treats ovarian cancer, particularly in patients with BRCA mutations, by inhibiting PARP enzymes and blocking cancer cell growth.
Managing Fallopian Tube Cancer: Rucaven 300 mg Tablet 60's provides treatment options for patients with fallopian tube cancer, offering a potential therapeutic benefit in managing the disease.
Therapy for Primary Peritoneal Cancer: Rucaven 300 mg Tablet 60's is effective in treating primary peritoneal cancer, helping to control tumor growth and improve patient outcomes.
Treatment of Prostate Cancer: Rucaven 300 mg Tablet 60's is used to treat certain cases of prostate cancer, especially those with specific genetic mutations, such as BRCA1 and BRCA2, providing a targeted treatment approach.

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Directions for Use

Rucaven 300 mg Tablet 60's can be taken with or without food.
Follow your doctor’s instructions on the dosage and timing of this medication. Try to take it at the same time each day or as recommended by a doctor for optimal results.
Swallow the whole tablet with a glass of water.
Do not break, chew or crush Rucaven 300 mg Tablet 60's.

Medicinal Benefits

Rucaven 300 mg Tablet 60's belongs to the group of anti-cancer medicines called PARP (poly adenosine diphosphate-ribose polymerase) indicated in the treatment of prostate cancer. It is also used to help maintain the response to other treatments for certain types of ovarian cancer, fallopian tube, and primary peritoneal cancer that have returned in adults who have partially or completely responded to other chemotherapy treatments and in people with a specific gene who have received treatment with at least two other chemotherapy treatments. Rucaven 300 mg Tablet 60's contains Rucaparib, which works by blocking an enzyme that repairs damaged DNA in the cancer cells, resulting in their death. Thereby, it kills cancer cells and helps treat cancer.

How Rucaven 300 mg Tablet 60's Works

Rucaven 300 mg Tablet 60's contains Rucaparib, which works by blocking an enzyme that repairs damaged DNA in cancer cells, resulting in their death. Thereby, it kills cancer cells and helps treat cancer.

Storage

• Store in a cool and dry place away from sunlight.• Keep Rucaven 300 mg Tablet 60's out of reach and sight of children.• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Side effects of Rucaven 300 mg Tablet

Nausea

Overcome Medication-Induced Nausea: A 9-Step Plan

Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
Divide your daily food intake into smaller, more frequent meals to reduce nausea.
Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
Use ginger (tea, ale, or candies) to help relieve nausea.
Get adequate rest and also avoid strenuous activities that can worsen nausea.
Talk to your doctor about taking anti-nausea medication if your nausea is severe.
Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.

Tiredness/ Weakness

Rest well; get enough sleep.
Eat a balanced diet and drink enough water.
Manage stress with yoga and meditation.
Limit alcohol and caffeine.
Physical activities like walking or jogging might help boost energy and make you feel less tired.

Vomiting

To prevent, manage, and treat Constipation caused by medication usage, follow these steps:

Preventing Vomiting (Before it Happens)
Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
Having a small meal before taking your medication can help reduce nausea and vomiting.
Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
Managing Vomiting (If it Happens)
Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
What to Do if Vomiting Persists
Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.

Anemia

Include iron-rich foods like dark leafy vegetables, lean red meat, legumes and fish in your diet.
Consume vitamin C-rich foods as they aid iron absorption.
Limit tea, cocoa, and coffee as these can slow iron absorption.
Exercise regularly; however, do not overdo it.

Taste Disturbance

Regularly brush and floss your teeth.
Rinse your mouth with water and baking soda a solution to neutralize acid in the mouth. This makes your food taste as it should.
Drink plenty of water or non-caffeinated drinks to prevent dry mouth which may lead to altered taste.
Try ginger, peppermint, fruit or green teas, lemonade, ginger ale or fruit juice to help mask unpleasant tastes.
Try sucking on sugar-free ice pops or ice cubes to prevent dry mouth.

Abnormal liver function test

High levels of liver enzymes need immediate medical attention.
Watch your diet and consume low-fat foods, like green leafy vegetables, fish, whole grains, nuts, etc.
Regularly do strengthening exercises to control your cholesterol levels.
Avoid drinking alcohol as it can affect your liver.
Focus on losing weight as it can help control cholesterol and maintain liver enzymes.
Practice yoga and meditation to improve liver functioning and overall health.

Constipation

Here are the steps to cope with constipation as a side effect of medication:

Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.

What if I have taken an overdose of Rucaven 300 mg Tablet 60's

Do not take more than prescribed dose. Using more medication will not improve your symptoms; rather they may cause poisoning or serious side-effects. If you suspect that you may have overdosed of Rucaven 300 mg Tablet 60's, please go to the emergency department of the closest hospital or nursing home.

Drug Warnings

Do not take Rucaven 300 mg Tablet 60's if you are allergic to any of its components or if you are pregnant or breastfeeding. Rucaven 300 mg Tablet 60's may cause serious side effects like bone marrow problems called Myelodysplastic Syndrome (MDS) or a type of cancer of the blood called Acute Myeloid Leukemia (AML). Seek immediate medical attention if you experience weakness, weight loss, fever, frequent infections, blood in urine or stools, feeling very tired, shortness of breath, and bleeding or bruising more easily. Consult your doctor immediately if you become pregnant during treatment with Rucaven 300 mg Tablet 60's. Let your doctor know if you are taking any other medicines, including supplements and herbal products.

Drug-Drug Interactions

RucaparibZiprasidone

Critical

RucaparibInfliximab

Severe

Drug-Drug Interactions

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RucaparibZiprasidone

Critical

How does the drug interact with Rucaven 300 mg Tablet:
Coadministration of Rucaven 300 mg Tablet and Ziprasidone may increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Rucaven 300 mg Tablet with Ziprasidone together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any symptoms such as sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not discontinue any medications without consulting a doctor.

RucaparibInfliximab

Severe

How does the drug interact with Rucaven 300 mg Tablet:
When Rucaven 300 mg Tablet is taken with Infliximab, can lead to or increase the risk or severity of developing serious infections.

How to manage the interaction:
Co-administration of Infliximab with Rucaven 300 mg Tablet can result in an interaction, but it can be taken if your doctor has advised it. However, if you experience symptoms of fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in sputum, weight loss, red or inflamed skin, body sores, and pain or burning during urination, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

RucaparibPirfenidone

Severe

How does the drug interact with Rucaven 300 mg Tablet:
Taking Pirfenidone with Rucaven 300 mg Tablet can increase the risk or severity of its side effects such as liver disease or gastric problems.

How to manage the interaction:
Co-administration of Pirfenidone with Rucaven 300 mg Tablet can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you have any of the following symptoms: fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, fatigue, lack of appetite, nausea, vomiting, abdominal pain, dark urine, light stools, and/or yellowing of the skin or eyes, consult a doctor immediately.

RucaparibSotalol

Severe

How does the drug interact with Rucaven 300 mg Tablet:
Using sotalol together with Rucaven 300 mg Tablet can increase the risk or severity of irregular heart rhythms which can be severe. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Although there is a possible interaction between Sotalol and Rucaven 300 mg Tablet, you can take these medicines together if prescribed by a doctor. If you experience dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations consult a doctor. Do not stop using any medications without talking to a doctor.

RucaparibMoxifloxacin

Severe

How does the drug interact with Rucaven 300 mg Tablet:
Using moxifloxacin together with Rucaven 300 mg Tablet can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Although there is a possible interaction between Moxifloxacin and Rucaven 300 mg Tablet, you can take these medicines together if prescribed by your doctor. If you notice any of these symptoms - like a fast or irregular heartbeat, severe or long-lasting diarrhea, vomiting, complications, sudden feeling dizzy or lightheaded, fainting, difficulty breathing, or feeling your heart beating fast - make sure to call your doctor right away. Do not stop using any medications without a doctor's advice.

RucaparibCladribine

Severe

How does the drug interact with Rucaven 300 mg Tablet:
Taking Rucaven 300 mg Tablet with Cladribine can increase the risk of developing serious infections.

How to manage the interaction:
There may be a possibility of interaction between Cladribine and Rucaven 300 mg Tablet, but it can be taken if prescribed by a doctor. If you have any of these symptoms, it's important to contact a doctor right away. These symptoms include fever, chills, diarrhea, sore throat, muscle aches, difficulty breathing, weight loss, and pain or burning when you urinate. Do not stop using any medications without a doctor's advice.

RucaparibGatifloxacin

Severe

How does the drug interact with Rucaven 300 mg Tablet:
Taking Gatifloxacin with Rucaven 300 mg Tablet can increase the risk or severity of irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Gatifloxacin with Rucaven 300 mg Tablet together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

Eat a healthy diet and exercise regularly to maintain a proper weight.
Avoid smoking and alcohol consumption.
Include vegetables, fruits, herbs, and spices in your diet.
Avoid fast food, fried food, processed meats, refined carbs, and added sugar.
Get optimal sleep; rest well.

Habit Forming

No

Therapeutic Class

CHEMOTHERAPY

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Alcohol

Consult your doctor

It is not known whether Rucaven 300 mg Tablet 60's interacts with alcohol. Please consult your doctor.

Pregnancy

Unsafe

Rucaven 300 mg Tablet 60's should not be used during pregnancy as it may harm your unborn baby.

Breast Feeding

Unsafe

Avoid breastfeeding whilst on treatment with Rucaven 300 mg Tablet 60's and for at least two weeks after the last dose.

Driving

Caution

In some cases, Rucaven 300 mg Tablet 60's may cause tiredness. So, drive or operate machinery only if you are alert.

Liver

Consult your doctor

If you have a history of liver disease, please inform your doctor before taking Rucaven 300 mg Tablet 60's.

Kidney

Consult your doctor

If you have a history of kidney disease, please inform your doctor before taking Rucaven 300 mg Tablet 60's.

Children

Unsafe

Rucaven 300 mg Tablet 60's is not recommended for children as the safety and effectiveness have not been established.

Heart

Rucaven 300 mg Tablet 60's may be used in patients with heart problems, but only with close monitoring due to potential cardiovascular side effects. Your doctor will assess your heart status and adjust treatment as needed.

Geriatrics

Caution

Rucaven 300 mg Tablet 60's is considered safe for elderly patients, but doctors monitor closely for side effects and organ function. No dose adjustment is typically needed unless other health issues are present.

FAQs

What is the use of Rucaven 300 mg Tablet 60's?

Rucaven 300 mg Tablet 60's is used treat Ovarian cancer, Fallopian tube cancer, Primary peritoneal cancer and Prostate cancer.

How does Rucaven 300 mg Tablet 60's work?

Rucaven 300 mg Tablet 60's works by blocking an enzyme that repairs damaged DNA in the cancer cells, resulting in their death. Thereby, it helps treat cancer.

Does Rucaven 300 mg Tablet 60's cause photosensitivity?

Rucaven 300 mg Tablet 60's may make your skin sensitive to sunlight. Therefore, avoid unnecessary or prolonged exposure to sunlight. Also, wear protective clothing and apply sunscreen.

Does Rucaven 300 mg Tablet 60's cause abdominal pain?

If you experience nausea, vomiting, diarrhoea, or abdominal pain, consult your doctor, as these may be signs that Rucaven 300 mg Tablet 60's is affecting your stomach or bowels.

Country of origin

India

Manufacturer/Marketer address

1st floor, 446/1, Sai krupa ventures, Lucien Life Sciences, Rd Number 20, Jubilee Hills, Hyderabad, Telangana 500033

Other Info - RUC0024

Author Details

Written By

Santoshini Reddy G

M Pharmacy

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Sep 18, 2025 | 11:50 AM IST

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