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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Rosave-C Capsule is a combination medication that contains Rosuvastatin (a statin) and Clopidogrel (an antiplatelet). It helps prevent heart attacks, strokes, and chest pain (angina) by lowering bad cholesterol and fats in the blood and preventing blood clots. Common side effects may include headache, nausea, ankle swelling, and a slow heartbeat. Take this medicine exactly as prescribed. Tell your doctor if you have liver problems, bleeding issues, or if you're pregnant, breastfeeding, or taking other blood thinners. Avoid drinking alcohol while on this medication.

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Manufacturer/Marketer :

Alembic Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Rosave-C Capsule

Rosave-C Capsule is a combination of two types of medicines: a statin and an antiplatelet. It is used to help prevent heart attacks, strokes, and chest pain (angina) in people who are at high risk of heart problems. A heart attack happens when the coronary arteries, blood vessels that supply blood and oxygen to the heart, become blocked by fatty deposits (plaques), including cholesterol. These plaques narrow the arteries, leading to atherosclerosis and coronary artery disease, which are the leading causes of most heart attacks.

Rosave-C Capsule contains two active ingredients that work together to protect your heart. Rosuvastatin lowers cholesterol production in the liver. It reduces bad cholesterol (LDL) and triglycerides (TG) while increasing good cholesterol (HDL). Clopidogrel is an antiplatelet medicine (blood thinner) that prevents blood cells (platelets) from clumping together and forming clots. Together, these medicines improve blood flow and reduce the risk of blocked arteries, helping prevent serious heart and brain complications.

Take Rosave-C Capsule exactly as prescribed by your doctor, usually once a day with or without food. Do not skip doses or stop taking the medicine without consulting a doctor. Common side effects may include headache, nausea, dizziness, swollen ankles (oedema), and in rare cases, slow heart rate. Most side effects are mild and go away on their own, but contact your doctor if they persist or worsen. If you miss a dose, take it as soon as you remember. If it’s almost time for your next dose, skip the missed one. Do not take two doses at the same time.

Do not stop taking Rosave-C Capsule without consulting your doctor, as stopping it suddenly may increase your risk of heart attack or stroke. Please inform your doctor of any medical conditions or allergies you may have before starting Rosave-C Capsule . Always inform your doctor that you are taking Rosave-C Capsule before any surgery or if a new medicine is prescribed. Rosave-C Capsule should not be used during pregnancy or breastfeeding, as it may harm the baby. It is also not recommended for use in children below 10 years.

Uses of Rosave-C Capsule

Rosave-C Capsule is used to reduce the risk of serious heart and blood vessel problems in people at high risk of cardiovascular disease. It is commonly prescribed for:

  • Prevention of heart attacks: It helps lower LDL (bad) cholesterol and reduces the formation of blood clots that could block the coronary arteries.
  • Prevention of strokes: It improves blood flow to the brain and decreases the risk of clot-related (thrombotic) events.
  • Management of chest pain (angina): It enhances the blood supply to the heart muscles, relieving chest pain and discomfort caused by reduced blood flow.
  • Slowing the progression of atherosclerosis: It reduces the buildup of cholesterol and plaque in blood vessels, helping to maintain healthy arteries.
  • Secondary prevention of cardiovascular events: It is used in people who have already had a heart attack, stroke, or undergone heart procedures such as angioplasty or bypass surgery to help prevent future events.

Directions for Use

  • Take Rosave-C Capsule with or without food as advised by your doctor.
  • It is recommended to follow your doctor’s recommendations regarding the dosage and duration.
  • Swallow it as a whole with a glass of water.
  • Do not crush, chew or break it.

Medicinal Benefits

  • Rosave-C Capsule effectively reduces the risk of heart attacks and strokes by lowering bad cholesterol and preventing blood clots.
  • Slows the progression of atherosclerosis, helping keep arteries open and reducing cardiovascular strain.
  • Provides dual protection. Rosuvastatin stabilises cholesterol plaques, while Clopidogrel prevents clot formation on them.
  • Improves long-term cardiovascular outcomes in patients with coronary artery disease or those who’ve had angioplasty or bypass surgery.
  • Lowers the chance of future cardiovascular events in high-risk individuals or those with a history of heart attack or stroke.

How Rosave-C Capsule Works

Rosave-C Capsule is a combination of two medications, Rosuvastatin and Clopidogrel, used to reduce the risk of heart attack, stroke, and other cardiovascular events. Rosuvastatin is a statin that lowers cholesterol by inhibiting the HMG-CoA reductase enzyme, thereby reducing levels of LDL (bad cholesterol) and triglycerides while increasing HDL (good cholesterol). Clopidogrel is an antiplatelet agent that prevents blood platelets from clumping together, helping to reduce the risk of harmful blood clots. Together, they work to manage high cholesterol and prevent clot-related complications, offering comprehensive protection against serious heart and blood vessel conditions.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Rosave-C Capsule
Here are the step-by-step strategies to manage the side effects of " Muscle Pain" caused by medication usage:
  • Report to Your Doctor: Inform your doctor about the muscle pain, as they may need to adjust your medication.
  • Stretch Regularly: Gentle stretching can help relieve muscle pain and stiffness.
  • Stay Hydrated: Adequate water intake supports muscle health by removing harmful substances and maintaining proper muscle function.
  • Warm or Cold Compresses: Apply cold or warm compresses to the affected area to reduce pain and inflammation.
  • Rest and Relaxation: Adequate rest helps alleviate muscle strain, while relaxation techniques like deep breathing and meditation can soothe muscle tightness, calm the mind, and promote relief from discomfort.
  • Gentle Exercise: Participate in low-impact activities, such as yoga or short walks, to improve flexibility, reduce muscle tension, and alleviate discomfort.
  • Consult a physician: If your symptoms don't improve or get worse, go to the doctor for help and guidance.
Here are the steps to manage Joint Pain caused by medication usage:
  • Please inform your doctor about joint pain symptoms, as they may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Your doctor may prescribe common pain relievers if necessary to treat joint discomfort.
  • Maintaining a healthy lifestyle is key to relieving joint discomfort. Regular exercise, such as low-impact sports like walking, cycling, or swimming, should be combined with a well-balanced diet. Aim for 7-8 hours of sleep per night to assist your body in repairing and rebuilding tissue.
  • Applying heat or cold packs to the affected joint can help reduce pain and inflammation.
  • Please track when joint pain occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
  • If your joint pain is severe or prolonged, consult a doctor to rule out any underlying disorders that may require treatment.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
Here are the steps to cope with constipation as a side effect of medication:
  • Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
  • Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
  • Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
  • Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
  • Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
  • Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.

What if I have taken an overdose of Rosave-C Capsule

Do not take more than the prescribed dose. Using more medication will not improve your symptoms; rather, they may cause poisoning or serious side effects. If you suspect that you may have overdosed of Rosave-C Capsule or if you experience any adverse events, please go to the emergency department of the closest hospital.

Drug Warnings

  • Do not take Rosave-C Capsule if you are allergic to any of its ingredients.
  • Do not use Rosave-C Capsule if you are pregnant, planning to become pregnant, or breastfeeding, as Rosuvastatin may harm the unborn baby and is strictly contraindicated during pregnancy.
  • Avoid Rosave-C Capsule if you have active liver disease or any active bleeding conditions, such as stomach ulcers or brain haemorrhage, unless specifically advised by your doctor.
  • Inform your doctor about all medications you are taking, especially antibiotics (like clarithromycin), antifungals (like itraconazole), HIV medicines, or blood thinners like warfarin, due to the risk of serious interactions.
  • Tell your doctor you are taking Rosave-C Capsule before any surgery or if a new medicine is being prescribed, to avoid potential complications or interactions.
  • Do not stop taking Rosave-C Capsule suddenly without medical advice, as this may increase the risk of heart attack, stroke, or other serious cardiovascular events.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Rosave-C Capsule:
Taking Rosave-C Capsule together with mifepristone increases the risk of vaginal bleeding in women.

How to manage the interaction:
Although taking Rosave-C Capsule with mifepristone is not recommended, that would certainly result in interaction, it can be taken if a doctor prescribes it. If you experience prolonged and heavy bleeding, consult a doctor immediately. Do not discontinue any medication without consulting a doctor.
How does the drug interact with Rosave-C Capsule:
When Selexipag and Rosave-C Capsule are taken together, the body's ability to break down Selexipag may be reduced.

How to manage the interaction:
Taking Rosave-C Capsule with Selexipag is not recommended, please consult your doctor before taking it. They can be taken if prescribed by your doctor.
How does the drug interact with Rosave-C Capsule:
Coadministration of Nicotinamide with Rosave-C Capsule may increase the risk and severity of side effects like rhabdomyolysis (breakdown of skeletal muscle) or kidney damage which can be fatal.

How to manage the interaction:
Taking Nicotinamide with Rosave-C Capsule together can result in an interaction, but it can be taken if your doctor has advised it. If you notice any symptoms like unexplained muscle pain, muscle stiffness or tenderness, fever, dark-coloured urine, or weakness, you should contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Rosave-C Capsule:
Co-administration of Rosave-C Capsule and Darunavir can increase the blood levels of Rosave-C Capsule and can increase the risk of liver damage and rhabdomyolysis(breakdown of skeletal muscle tissue).

How to manage the interaction:
Co-administration of Rosave-C Capsule and Darunavir can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like muscle pain, tenderness, weakness, dark-colored urine, fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, and yellowing of the skin or eyes, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Rosave-C Capsule:
Co-administration of Gemfibrozil and Rosave-C Capsule may increase the risk or severity of side effects like muscle injury.

How to manage the interaction:
Co-administration of Gemfibrozil and Rosave-C Capsule can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like muscle pain, tenderness, weakness, or dark-colored urine, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Rosave-C Capsule:
Co-administration of leflunomide and Rosave-C Capsule can increase the risk of developing liver problems.

How to manage the interaction:
Co-administration of Leflunomide and Rosave-C Capsule can lead to an interaction, they can be taken together if prescribed by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, or yellowing of the skin or eyes, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Rosave-C Capsule:
Co-administration of ciclosporin with Rosave-C Capsule can increase blood levels of Rosave-C Capsule. This can increase the risk of developing side effects.

How to manage the interaction:
Co-administration of cyclosporine and Rosave-C Capsule can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like muscle pain, tenderness, weakness, or dark-colored urine, light colour stools, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
RosuvastatinSaquinavir
Severe
How does the drug interact with Rosave-C Capsule:
Co-administration of Saquinavir and Rosave-C Capsule can increase the blood levels of Rosave-C Capsule and can increase the risk of developing liver damage and rhabdomyolysis(breakdown of skeletal muscle tissue).

How to manage the interaction:
Co-administration of Saquinavir and Rosave-C Capsule can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like muscle pain, tenderness, weakness, dark-colored urine, fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, and yellowing of the skin or eyes, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Rosave-C Capsule:
Co-administration of Rosave-C Capsule and Fenofibrate can increase the blood levels of Rosave-C Capsule and can increase the risk of liver damage and rhabdomyolysis(breakdown of skeletal muscle tissue).

How to manage the interaction:
Co-administration of Rosave-C Capsule and Fenofibrate can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like muscle pain, tenderness, weakness, dark-colored urine, fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, and yellowing of the skin or eyes, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Rosave-C Capsule:
Taking Rosave-C Capsule with clopidogrel can increase the blood levels of Rosave-C Capsule. This can increase the risk of side effects.

How to manage the interaction:
Although taking clopidogrel together with Rosave-C Capsule may result in an interaction, it can be taken if prescribed by your doctor. However, consult your doctor immediately if you experience chills, joint pain or swelling, skin rash, itching, nausea, vomiting, dark-colored urine, and/or yellowing of the skin or eyes. Do not discontinue any medication without consulting your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Follow a Mediterranean or DASH diet rich in vegetables, fruits, whole grains, legumes, nuts, and healthy fats, such as olive oil, which has been shown to reduce the risk of cardiovascular events.
  • Limit your intake of saturated fats and eliminate trans fats to lower LDL cholesterol and reduce your risk of atherosclerosis.
  • Reduce sodium intake to less than 2,300 mg per day to help control blood pressure and lower the risk of stroke and heart disease.
  • Engage in at least 150 minutes of moderate aerobic exercise per week, such as brisk walking, swimming, or cycling, to improve heart health and cholesterol levels.
  • Quit smoking and avoid secondhand smoke exposure, as tobacco significantly increases the risk of clot formation and arterial damage.
  • Limit alcohol consumption to no more than one standard drink per day for women and two for men, as excessive alcohol raises blood pressure and cardiovascular risk.
  • Maintain a healthy weight (BMI 18.5–24.9); even modest weight loss improves cholesterol, blood pressure, and blood sugar control.
  • Manage blood sugar effectively, especially in patients with diabetes, to prevent accelerated vascular damage and cardiovascular complications.
  • Reduce chronic stress through techniques like mindfulness, relaxation, or yoga, and aim for 7–8 hours of quality sleep to support overall cardiovascular health.
  • Take medications like Rosuvastatin and Clopidogrel exactly as prescribed, and attend regular medical check-ups to monitor lipid levels, clotting function, and overall cardiovascular risk.

Habit Forming

No

Therapeutic Class

ANTICOAGULANT/ANTITHROMBOTIC
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Alcohol

Unsafe

Rosave-C Capsule should not be taken with alcohol as it may worsen your liver condition with increased secretion of liver enzymes like transaminase. Keep your doctor informed if you drink alcohol.

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Pregnancy

Unsafe

Rosave-C Capsule contains Rosuvastatin, which is a pregnancy category X medicine. It may cause harm to both the pregnant mother and the fetus. Hence, it is not recommended for pregnant women and those who are planning for a pregnancy. Your doctor may prescribe it only in extreme cases.

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Breast Feeding

Caution

Take Rosave-C Capsule only when prescribed, it is known to pass on in a limited quantity via breast milk to the child.

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Driving

Caution

Drive with caution, Rosave-C Capsule usually causes blurry vision and may affect driving ability.

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Liver

Caution

Rosave-C Capsule to be taken with caution, especially if you have a history of liver diseases/conditions. The dose may have to be adjusted by your doctor.

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Kidney

Caution

Rosave-C Capsule to be taken with caution, especially if you have a history of kidney diseases/conditions. The dose may have to be adjusted by your doctor.

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Children

Caution

Rosave-C Capsule is not recommended for children below the age of 10 years. The safety and effectiveness of Rosave-C Capsule have not been established in children due to limited testing of Rosave-C Capsule on children by competent authorities worldwide.

Have a query?

FAQs

Rosave-C Capsule is used to prevent heart attacks and strokes in the future. It lowers the raised level of cholesterol and fats (triglycerides) in the body.

Rosave-C Capsule is composed of two medicines, namely: Rosuvastatin and Clopidogrel. Rosuvastatin is a lipid-lowering medication that inhibits the enzyme responsible for producing cholesterol in the body. As a result, it lowers the bad cholesterol (low-density lipoproteins or LDL) and triglycerides (TG), and increases the levels of good cholesterol (high-density lipoproteins or HDL). Clopidogrel is a blood thinner (anticoagulant) that collectively prevents the formation of clots in the blood vessels. Together, Rosave-C Capsule reduces the increased levels of bad cholesterol (low-density lipoprotein and triglycerides) and prevents blood clots, thereby reducing the risk of heart attack, stroke, and heart-related chest pain (angina).

Yes, Rosave-C Capsule contains clopidogrel that prevents blood clotting. It works by preventing platelets (a type of blood cell) from sticking together and forming clots, thereby preventing heart attacks and strokes.

No, Rosave-C Capsule contains Rosuvastatin, pregnancy category X medicine, and can harm both pregnant mother and unborn baby. Even if you are planning for pregnancy, tell your doctor that you are using Rosave-C Capsule .

If you accidentally take an overdose of Rosave-C Capsule , you may have liver problems (increased secretion of liver enzymes) and bleeding complications. If problems persist, please go to the nearest clinic or hospital immediately.

It would be best if you had total lipid profile (TG, HDL, LDL, VLDL, TC) and Blood coagulation tests like Complete blood count (CBC), Factor V assay, Fibrinogen Test, Prothrombin time (PT or PT-INR), Platelet count, Thrombin time and Bleeding time to analyze your blood clot timing and cholesterol level.

Do not drink grapefruit juice while taking Rosave-C Capsule . Grapefruit juice may increase the blood-thinning effect of your medicine.

Yes, prolonged use of Rosave-C Capsule may cause muscle diseases like myopathy and rhabdomyolysis. So if you feel any musculoskeletal pain after taking Rosave-C Capsule , consult your doctor about this issue.

Yes, taking Rosave-C Capsule can increase bleeding risk as it contains aspirin and clopidogrel, which belong to a class of blood-thinning agents. Therefore, please exercise caution when shaving, cutting fingernails or toenails, or using sharp objects to prevent bleeding. Before undergoing any surgical procedure, please inform your doctor that you are taking Rosave-C Capsule .

Consult your doctor before taking other medications while on treatment with Rosave-C Capsule to prevent any potential interactions. Let the doctor know if you are taking antibiotics, anti-HIV drugs, antifungal, blood thinners, anti-arthritis medicines, oral contraceptives, cardiac medicines or immunosuppressants.

If you are due to undergo any surgery or dental procedure, inform the doctor that you are taking Rosave-C Capsule . The doctor might ask you to stop Rosave-C Capsule before surgery as it might increase the risk of bleeding.

Follow a healthy diet and exercise regularly. Avoid smoking and alcohol consumption. Manage stress by doing meditation. Be cautious while using sharp objects.

It might be safe to use paracetamol while taking Rosave-C Capsule as other painkillers may increase the risk of bleeding. However, consult the doctor before using any painkiller medicines.

Side effects of Rosave-C Capsule include headaches, ankle swelling due to fluid retention (oedema), slow heart rate, and nausea. If the side effects are persistent, reach out to your doctor.

Country of origin

India

Manufacturer/Marketer address

Alembic Road, Vadodara - 390 003, Gujarat,INDIA
Other Info - ROS0436

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