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compositionComposition:RITUXIMAB-100MG
prescriptionPrescription Medicine
Rituxem 100 mg/10 ml Injection 10 ml

Rituxem 100 mg/10ml Injection is used to treat Non-Hodgkin's disease, rheumatoid arthritis, chronic lymphocytic leukaemia, granulomatosis and pemphigus vulgaris. It contains Rituximab, which works by inhibiting the DNA and RNA transcription that is essential for cancer cell growth. This helps prevent the growth and further spread of cancerous or non-cancerous cells. On the other hand, It works by interfering with the immune system process that causes inflammation in the joint tissues. Thus, it reduces pain and inflammation and prevents joint damage and disease progression over time.

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Written By Lakshmithulasi Yarragunta ,
Reviewed By Santoshini Reddy G , M Pharmacy
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More about the Product

Composition :

RITUXIMAB-100MG

Manufacturer/Marketer :

Emcure Pharmaceuticals Ltd

Consume Type :

Parenteral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Rituxem 100 mg/10ml Injection

Rituxem 100 mg/10ml Injection belongs to a class of medicines called monoclonal antibodies used in the treatment of non-Hodgkin’s disease and chronic lymphocytic leukaemia. This medicine is also used in treating rheumatoid arthritis in combination with methotrexate and granulomatosis in combination with glucocorticoids. It is also used to treat Pemphigus Vulgaris (PV) and mature B-cell acute leukaemia (B-AL).

Rituxem 100 mg/10ml Injection contains Rituximab, which works by inhibiting the DNA and RNA transcription that is essential for cancer cell growth. This helps prevent the growth and further spread of cancerous or non-cancerous cells. On the other hand, Rituxem 100 mg/10ml Injection works by interfering with the immune system process that causes inflammation in the joint tissues. Thus, it reduces pain and inflammation and prevents joint damage and disease progression over time

Rituxem 100 mg/10ml Injection may cause certain side effects, such as pale skin, painful urination, night sweats, flushing, back pain, nausea, vomiting, diarrhoea, stomach pain, mouth sores, peeling of skin, injection site reactions and pain at the site of injection. These side effects do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor. Rituxem 100 mg/10ml Injection is a parenteral preparation. A trained healthcare professional will administer it. Hence, do not self-administer.

Rituxem 100 mg/10ml Injection should be avoided if you are allergic to it or any other components present in it. Let your doctor know about your complete medical history, including current medication, to rule out any side effects/interactions. Also, inform your doctor if you have liver/kidney disease, hepatitis B virus infection, cardiac disorders, any active infections, or gastrointestinal disorders before receiving this injection. Rituxem 100 mg/10ml Injection may cause bowel obstruction and perforation, reactivation of Hepatitis B infection, Cardiac arrhythmias, tumour lysis syndrome, and angina in some patients. Hence, careful monitoring should be done during the entire treatment. Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding.

Uses of Rituxem 100 mg/10ml Injection

Rituxem 100 mg/10ml Injection is used in the treatment of Non-Hodgkin’s disease, rheumatoid arthritis, chronic lymphocytic leukaemia, granulomatosis and pemphigus vulgaris. The detailed uses of Rituxem 100 mg/10ml Injection are as follows:

  • Non-Hodgkin’s Lymphoma (NHL) : Rituxem 100 mg/10ml Injection is used to treat Non-Hodgkin’s Lymphoma alone or with chemotherapy.
  • Chronic Lymphocytic Leukemia (CLL) : Rituxem 100 mg/10ml Injection is used in the treatment of Chronic Lymphocytic Leukemia (CLL) and B-cell Acute Lymphoblastic Leukemia (B-ALL.
  • Rheumatoid Arthritis (RA): Rituxem 100 mg/10ml Injection is used in the treatment of rheumatoid arthritis.
  • Granulomatosis with Polyangiitis (GPA) and Microscopic Polyangiitis (MPA): Rituxem 100 mg/10ml Injection helps to treat Granulomatosis with Polyangiitis and Microscopic Polyangiitis.
  • Pemphigus Vulgaris: Rituxem 100 mg/10ml Injection is used to treat pemphigus vulgaris for moderate to severe cases.

Key Benefits

Rituxem 100 mg/10ml Injection contains Rituximab, which belongs to the class of monoclonal antibodies. It works by inhibiting the DNA and RNA transcription that is essential for cancer cell growth. This helps prevent the growth and further spread of cancerous or non-cancerous cells. On the other hand, Rituxem 100 mg/10ml Injection works by interfering with the immune system process that causes inflammation in the joint tissues. Thus, it reduces pain and inflammation and prevents joint damage and disease progression over time.

Side effects of Rituxem 100 mg/10 ml Injection 10 ml
Here's a comprehensive approach to managing medication-triggered fever:
  • Inform your doctor immediately if you experience a fever after starting a new medication.
  • Your doctor may adjust your medication regimen or dosage as needed to minimize fever symptoms.
  • Monitor your body temperature to monitor fever progression.
  • Drink plenty of fluids, such as water or electrolyte-rich beverages, to help your body regulate temperature.
  • Get plenty of rest and engage in relaxation techniques, such as deep breathing or meditation, to help manage fever symptoms.
  • Under the guidance of your doctor, consider taking medication, such as acetaminophen or ibuprofen, to help reduce fever.
  • If your fever is extremely high (over 103°F), or if you experience severe symptoms such as confusion, seizures, or difficulty breathing, seek immediate medical attention.
  • Nourish your body with a balanced diet with protein-rich foods like fish, eggs, and beans. Fruits, vegetables, and nuts provide essential vitamins and minerals. If necessary, consider vitamin B12 and folate supplements.
  • Practice good hygiene to protect yourself from infections. Wash your hands often, stay up-to-date on vaccinations, avoid crowded areas, and take care when handling food, pets, and diapers.
  • Aim for a good night's sleep, targeting 8 hours of sleep. Find calm through stress-reducing practices like yoga, meditation, or deep breathing. Regular physical activity can also help.
  • Stay healthy by drinking plenty of water, eating probiotic-rich foods like yoghurt, and limiting processed foods and sugars. Consult your doctor, if you are having difficulties or concerns.
  • Rest well; get enough sleep.
  • Wear comfortable layers of clothes and get to a warm place.
  • Drink warm fluids like coffee, tea or hot chocolate.
  • Warm up using a blanket or heating pad.
  • Talk to your doctor about medicines to manage neutropenia based on the underlying cause.
  • Avoid contact with people who are sick.
  • Wash your hands regularly with soap and water.
  • Avoid unpasteurized dairy products.
Here are the steps to manage the medication-triggered Upper respiratory tract infection:
  • Inform your doctor about the symptoms you're experiencing due to medication.
  • Your doctor may adjust your treatment plan, which could include changing your medication, adding new medications, or offering advice on managing your symptoms.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • Stay hydrated by drinking plenty of fluids to help loosen and clear mucus from your nose, throat, and airways.
  • Get plenty of rest and engage in stress-reducing activities to help your body recover. If your symptoms don't subside or worsen, consult your doctor for further guidance.
Here are the steps to manage the medication-triggered Common Cold:
  • Inform your doctor about the common cold symptoms you're experiencing due to medication.
  • Your doctor may adjust your treatment plan, which could include changing your medication, adding new medications, or offering advice on managing your symptoms.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • Drink plenty of fluids, such as warm water or soup, to help thin out mucus.
  • Get plenty of rest and engage in stress-reducing activities to help your body recover. If your symptoms don't subside or worsen, consult your doctor for further guidance.

Directions for Use

  • Follow your doctor’s instructions on the dosage and timing of this medication to ensure safety.
  • Rituxem 100 mg/10ml Injection will be administered by the doctor or healthcare professional.
  • Do not self-administer.

How Rituxem 100 mg/10ml Injection Works

Rituxem 100 mg/10ml Injection contains Rituximab, which works by inhibiting the DNA and RNA transcription that is essential for cancer cell growth. This helps prevent the growth and further spread of cancerous or non-cancerous cells. On the other hand, Rituxem 100 mg/10ml Injection works by interfering with the immune system process that causes inflammation in the joint tissues. Thus, it reduces pain and inflammation and prevents joint damage and disease progression over time.
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Alcohol

Consult your doctor

It is not known if alcohol interacts with Rituxem 100 mg/10ml Injection. Please consult the doctor.

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Pregnancy

Caution

If you are pregnant or planning pregnancy, inform your doctor before receiving Rituxem 100 mg/10ml Injection. Your doctor may prescribe this medicine if the benefits outweigh the risks.

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Breast Feeding

Caution

If you are a nursing mother, inform your doctor before receiving Rituxem 100 mg/10ml Injection. Your doctor may prescribe this medicine if the benefits outweigh the risks.

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Driving

Not applicable

Rituxem 100 mg/10ml Injection will be administered in the hospital setting. Hence, avoid driving.

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Liver

Caution

If you have a pre-existing or a history of liver disease, inform your doctor before receiving Rituxem 100 mg/10ml Injection. A dose adjustment of this medicine or a suitable alternative may be advised based on your condition.

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Kidney

Caution

If you have a pre-existing or a history of kidney disease, inform your doctor before receiving Rituxem 100 mg/10ml Injection. A dose adjustment of this medicine or a suitable alternative may be advised based on your condition.

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Children

Consult your doctor

Rituxem 100 mg/10ml Injection will be given to the children only if needed. If administered, careful monitoring of the child is needed.

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Heart

Caution

Rituxem 100 mg/10ml Injection may increase the risk of heart problems. Therefore, please inform your doctor if you have any heart-related problems before using Rituxem 100 mg/10ml Injection.

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Geriatrics

Caution

Rituxem 100 mg/10ml Injection should be used with caution in elderly people. Therefore, please consult your doctor before using Rituxem 100 mg/10ml Injection.

What if I have taken an overdose of Rituxem 100 mg/10ml Injection

Since Rituxem 100 mg/10ml Injection is given in a controlled medical setting by a healthcare professional, an overdose is not likely to occur. If you think there has been an overdose or experiencing any adverse events, get medical care right away. In a medical setting, an overdose would be treated quickly.

Diet & Lifestyle Advise

  • After your treatment begins, dietary adjustments can help you control side effects.
  • Anyone suffering from a chronic illness, including cancer, should consume foods high in protein, healthy fats, whole grains, and vitamins and minerals.
  • Plant-based proteins are among the greatest meals to take during chemotherapy or other cancer treatments. They have the highest concentrations of vitamins and minerals, such as nuts, seeds, beans, and legumes.
  • Eat a healthy diet and exercise regularly to maintain proper weight.
  • Include leafy vegetables, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, and herbs.
  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
  • Get optimal sleep; rest well.
  • Avoid smoking and alcohol consumption.
  • Avoid fast and fried food, processed meats, refined carbs and added sugars.

Have a query?

How Soon It Starts Working

The time required for Rituxem 100 mg/10ml Injection to start to work: The exact onset of time for Rituxem 100 mg/10ml Injection is unknown. The time for which the effects of Rituxem 100 mg/10ml Injection last: The duration of Rituxem 100 mg/10ml Injection effect is unknown.

What if you forget to take Rituxem 100 mg/10ml Injection

As this medicine is administered in a hospital by your healthcare professional, the chances of missing a dose are less. However, if you have any concerns, contact your doctor.

Storage

• Store in a cool and dry place away from sunlight. • Keep Rituxem 100 mg/10ml Injection out of the sight and reach of children. • Cold chain - To be stored in cold places at 2ºC to 8ºC.
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Keep Refrigerated. Do not freeze.Prepaid payment required.

Drug Warnings

Rituxem 100 mg/10ml Injection should be avoided if you are allergic to it or any other components present in it. Let your doctor know about your complete medical history, including current medication, to rule out any side effects/interactions. Before administration, inform your doctor if you have liver/kidney disease, hepatitis B Virus infection, cardiac disorders, any active infections, or gastrointestinal disorders. Rituxem 100 mg/10ml Injection may cause bowel obstruction and perforation, reactivation of Hepatitis B infection, Cardiac arrhythmias, tumour lysis syndrome (tumour cells release their contents into the bloodstream), and angina in some patients. Hence, careful monitoring should be done during the entire treatment. Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding.

Drug-Drug Interactions

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Drug-Drug Interactions: Rituxem 100 mg/10ml Injection may interact with vaccines, antineoplastic drugs (cisplatin), and other medicines.

Drug-Food Interactions: No interactions found.

Drug-Disease Interactions: Inform your doctor if you have kidney or liver disease, gastrointestinal disorders, and pulmonary disorders before receiving Rituxem 100 mg/10ml Injection.

RituximabRotavirus vaccine
Critical
RituximabCladribine
Severe

Drug-Drug Interactions

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RituximabRotavirus vaccine
Critical
How does the drug interact with Rituxem 100 mg/10 ml Injection 10 ml:
Taking Rituxem 100 mg/10 ml Injection 10 ml and Rotavirus vaccine together may increase risk of side effects.

How to manage the interaction:
Taking Rituxem 100 mg/10 ml Injection 10 ml with Rotavirus vaccine is not recommended as it can possibly result in an interaction, it can be taken if a doctor has prescribed it. In case you experience any unusual symptoms, consult a doctor. Do not stop using any medications without consulting a doctor.
RituximabCladribine
Severe
How does the drug interact with Rituxem 100 mg/10 ml Injection 10 ml:
Combining Rituxem 100 mg/10 ml Injection 10 ml with Cladribine can increase the risk of infections.

How to manage the interaction:
Co-administration of Cladribine with Rituxem 100 mg/10 ml Injection 10 ml can possibly result in an interaction, but it can be taken if your doctor has advised it. However, consult your doctor if you experience fever, chills, loose stools, sore throat, muscle aches, difficulty breathing, and pain or burning sensation while urinating. Do not stop using any medications without talking to a doctor.
RituximabNatalizumab
Severe
How does the drug interact with Rituxem 100 mg/10 ml Injection 10 ml:
Combining Rituxem 100 mg/10 ml Injection 10 ml with Natalizumab may increase the risk of infections.

How to manage the interaction:
Although taking Rituxem 100 mg/10 ml Injection 10 ml and Natalizumab together can evidently cause an interaction, it can be taken if your doctor has suggested it. However, consult the doctor immediately if you experience symptoms such as fever, chills, loose stools, sore throat, muscle aches, shortness of breath, blood in phlegm, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without consulting a doctor.
RituximabBaricitinib
Severe
How does the drug interact with Rituxem 100 mg/10 ml Injection 10 ml:
Taking Rituxem 100 mg/10 ml Injection 10 ml with Baricitinib may significantly increases the risk of infections.

How to manage the interaction:
Although taking Rituxem 100 mg/10 ml Injection 10 ml and Baricitinib together can cause an interaction, it can be taken if A doctor has suggested it. However, consult the doctor immediately if you experience symptoms such as fever, chills, loose stools, sore throat, muscle aches, breathing difficulty, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without consulting a doctor.
RituximabInfliximab
Severe
How does the drug interact with Rituxem 100 mg/10 ml Injection 10 ml:
Taking Infliximab with Rituxem 100 mg/10 ml Injection 10 ml may increase the risk of infections.

How to manage the interaction:
Taking Rituxem 100 mg/10 ml Injection 10 ml with Infliximab together can result in an interaction, but it can be taken if your doctor has advised it. However, consult the doctor immediately if you experience symptoms such as fever, chills, loose stools, sore throat, muscle aches, shortness of breath, blood in phlegm, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without talking to a doctor.
RituximabClozapine
Severe
How does the drug interact with Rituxem 100 mg/10 ml Injection 10 ml:
Taking Rituxem 100 mg/10 ml Injection 10 ml with Clozapine can increase the risk of infections.

How to manage the interaction:
Although taking Rituxem 100 mg/10 ml Injection 10 ml and Clozapine together can evidently cause an interaction, it can be taken if your doctor has suggested it. However, consult your doctor if you experience fever, chills, loose stools, sore throat, muscle aches, shortness of breath, blood in phlegm, red or inflamed skin, body sores, and pain or burning during urination. Do not discontinue any medications without consulting a doctor.
RituximabAdalimumab
Severe
How does the drug interact with Rituxem 100 mg/10 ml Injection 10 ml:
Taking adalimumab with Rituxem 100 mg/10 ml Injection 10 ml may increase the risk of infections.

How to manage the interaction:
Co-administration of Rituxem 100 mg/10 ml Injection 10 ml with Adalimumab can result in an interaction, but it can be taken if your doctor has advised it. However, consult the doctor immediately if you experience symptoms such as fever, chills, loose stools, sore throat, muscle aches, shortness of breath, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without consulting a doctor.
RituximabDeferiprone
Severe
How does the drug interact with Rituxem 100 mg/10 ml Injection 10 ml:
Taking Rituxem 100 mg/10 ml Injection 10 ml with Deferiprone may increase the risk of infections.

How to manage the interaction:
Taking Rituxem 100 mg/10 ml Injection 10 ml with Deferiprone together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, consult the doctor immediately if you experience symptoms such as fever, chills, loose stools, sore throat, muscle aches, shortness of breath, blood in phlegm, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without consulting a doctor.
RituximabLeflunomide
Severe
How does the drug interact with Rituxem 100 mg/10 ml Injection 10 ml:
Taking Rituxem 100 mg/10 ml Injection 10 ml with Leflunomide can increase the risk of infections.

How to manage the interaction:
Taking Rituxem 100 mg/10 ml Injection 10 ml with Leflunomide together can result in an interaction, it can be taken if your doctor has advised it. However, consult the doctor immediately if you experience fatigue, dizziness, lightheadedness, unusual bleeding or bruising, fever, chills, loose stools, sore throat, muscle aches, shortness of breath, blood in phlegm, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without a doctor's advice.
RituximabTofacitinib
Severe
How does the drug interact with Rituxem 100 mg/10 ml Injection 10 ml:
Taking Rituxem 100 mg/10 ml Injection 10 ml and Tofacitinib may increase the risk infections.

How to manage the interaction:
Taking Tofacitinib with Rituxem 100 mg/10 ml Injection 10 ml together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, consult the doctor immediately if you experience symptoms such as fever, chills, loose stools, sore throat, muscle aches, shortness of breath, blood in phlegm, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Therapeutic Class

[CHEMOTHERAPY]

FAQs

Rituxem 100 mg/10ml Injection is used to treat Non-Hodgkin’s disease, rheumatoid arthritis, chronic lymphocytic leukaemia, granulomatosis and pemphigus vulgaris.

Rituxem 100 mg/10ml Injection contains Rituximab, which works by inhibiting the DNA and RNA transcription that is essential for cancer cell growth.

Rituxem 100 mg/10ml Injection may cause bowel obstruction and perforation, reactivation of Hepatitis B infection, Cardiac arrhythmias, tumour lysis syndrome, and angina in some patients. Hence, inform your oncologist about your complete medical history, including current medication, to rule out any side effects/interactions.

Rituxem 100 mg/10ml Injection contains the active substance rituximab. This is a type of protein called a monoclonal antibody.

The common side effects of Rituxem 100 mg/10ml Injection are pale skin, painful urination, night sweats, flushing, back pain, nausea, vomiting, diarrhoea, stomach pain, mouth sores, peeling of skin, injection site reactions and pain at the site of injection. If any of these side effects persist or worsen, please consult your doctor.

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Author Details

Santoshini Reddy GDoctor badge

Reviewed By

  • Santoshini Reddy G

    M Pharmacy

Last Updated

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Country of origin

India

Manufacturer/Marketer address

A €“ 504, Shapath-4, B/S Hotel Crowne Plaza, Opp. Karnavati Club, S. G. Highway ,Ahmedabad 380 051 Gujarat
Other Info - RIT0185
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