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Risorine Kit is primarily used to treat tuberculosis (TB). Tuberculosis is an infectious disease that mainly affects the lungs but can also spread to other body parts such as kidneys, brain, spine, and bone marrow. It contains Rifampicin, Ethambutol, Isoniazid, Piperine and Pyrazinamide. Risorine Kit works by killing the bacteria named Mycobacterium tuberculosis, which causes TB (tuberculosis). Thus, it helps treat tuberculosis. In some cases, this medicine may cause side effects such as nausea, vomiting, stomach pain, headache, and dizziness.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

ETHAMBUTOL-800MG+ISONIAZID-300MG+PIPERINE-10MG+PYRAZINAMIDE-750MG+RIFAMPICIN-200MG

Manufacturer/Marketer :

Cadila Healthcare Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Risorine Kit

Risorine Kit is an oral prescription medication used to treat tuberculosis (TB), a bacterial infection that primarily affects the lungs. The medical purpose of this combination therapy is to completely eliminate TB bacteria from the body and prevent the infection from spreading. It is highly effective when taken exactly as directed by your healthcare provider.

To work effectively, Risorine Kit must be taken daily and with absolute consistency to prevent the bacteria from becoming resistant to the treatment. It is best to take this medicine on an empty stomach, either one hour before or two hours after a meal, with a full glass of water. Eating a balanced, nutrient-dense diet and getting plenty of rest can help your body recover faster during treatment.

While taking Risorine Kit, you may experience mild side effects, such as a harmless red-orange discoloration of your urine, sweat, or saliva. However, you must contact your doctor immediately if you experience serious side effects, such as yellowing of your eyes or skin, severe stomach pain, or changes in your vision.

Do not take this if you have severe liver damage or have had a severe allergic reaction to this medication in the past. Before starting, talk to your doctor if you have a history of liver disease, kidney issues, gout, or diabetes.

This medication can interact with other substances, including alcohol, which significantly increases your risk of liver damage, and certain other prescription drugs like blood thinners or hormonal birth control. If you are pregnant, breastfeeding, or elderly, you must consult your doctor to discuss the risks and benefits before starting treatment.

Uses of Risorine Kit

Risorine Kit is used in the treatment of Tuberculosis. The detailed uses of Risorine Kit are as follows:

  • Tuberculosis (TB): Risorine Kit is prescribed to treat active tuberculosis infections in the lungs and other parts of the body by stopping the growth and spread of the responsible bacteria.

Key Benefits

  • Helps treat tuberculosis effectively by attacking TB bacteria in multiple ways.
  • Supports faster recovery, helping improve overall strength and lung health.
  • Combines multiple medicines in one dose, making treatment simpler and easier to follow.
  • Reduces the risk of drug-resistant TB by using a combination of anti-TB medicines.
  • Lowers the number of TB bacteria in the body, helping clear the infection.
  • Helps reduce the spread of TB to family members and others when taken as prescribed.
  • Improves the chances of successful treatment by encouraging completion of the full course.

Directions for Use

  • Take Risorine Kit on an empty stomach for optimal absorption.
  • Follow your doctor's instructions on the dosage and timing of this medication, to ensure the safety.
  • Swallow the medicine as a whole with a glass of water.
  • Do not crush, break, or chew it.

How Risorine Kit Works

Risorine Kit contains five active components that work together to kill tuberculosis (TB) bacteria in different ways, helping prevent the bacteria from surviving or becoming resistant to treatment. •Rifampicin blocks a bacterial enzyme called RNA polymerase, preventing the TB bacteria from making the RNA needed to produce essential proteins. Without these proteins, the bacteria cannot survive or multiply. •Isoniazid prevents the bacteria from making mycolic acids, which are essential building blocks of their protective outer cell wall. Without this protective layer, the bacteria become weak and die. •Pyrazinamide works best in the acidic environment inside infected cells, where dormant TB bacteria often hide. It helps destroy these difficult-to-reach bacteria, reducing the chance of the infection returning. •Ethambutol slows bacterial growth by preventing the bacteria from building important components of their cell wall. This makes it harder for the bacteria to multiply and helps the other anti-TB medicines work more effectively. •Piperine is included in some formulations to improve the absorption (bioavailability) of certain medicines in the combination, which may help them work more effectively. However, piperine is not included in all tuberculosis treatment regimens, so you should always take the exact brand or formulation prescribed by your doctor. •By attacking TB bacteria through several different mechanisms at the same time, this combination effectively treats the infection while helping reduce the risk of antibiotic resistance.
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Alcohol

Caution

Avoid alcohol consumption while taking Risorine Kit as it could lead to unpleasant side effects.

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Pregnancy

Caution

Please consult your doctor if you are pregnant; your doctor will prescribe Risorine Kit only if the benefits outweigh the risks.

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Breast Feeding

Caution

Risorine Kit may pass into breast milk. Please consult the doctor if you are breastfeeding.

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Driving

Caution

Risorine Kit may cause dizziness, numbness and tingling in hands and feet. Do not drive or operate machinery if you experience these symptoms.

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Liver

Caution

Dose adjustment may be needed. Please consult your doctor if you have liver impairment/liver disease before taking Risorine Kit.

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Kidney

Caution

Dose adjustment may be needed. Please consult your doctor if you have any concerns regarding this or if you have kidney impairment/kidney disease before taking Risorine Kit.

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Children

Caution

Please consult the doctor if you have any concerns regarding the usage of Risorine Kit in children.

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Heart

Caution

Risorine Kit should be avoided in individuals with heart problems unless specifically prescribed. It can affect liver function and interact with cardiac drugs, potentially worsening heart conditions. Always consult your doctor before starting it.

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Geriatrics

Caution

Risorine Kit should be avoided in geriatric patients unless prescribed, as it may cause liver toxicity, nerve issues, and interact with age-related conditions. Always consult your doctor to assess risks and ensure safe use.

What if I have taken an overdose of Risorine Kit

In case of an accidental overdose, seek immediate medical attention or contact your local poison control center right away. Overdose symptoms may include severe nausea, vomiting, drowsiness, or yellowing of the skin.

Diet & Lifestyle Advise

  • Avoid alcohol completely: Drinking alcohol while taking this medicine greatly increases the risk of liver damage.
  • Take Vitamin B6 (pyridoxine): If your doctor prescribes Vitamin B6, take it regularly as directed to help reduce the risk of numbness or tingling caused mainly by the isoniazid component.
  • Eat a nutritious, high-protein diet: Include lean meats, eggs, fish, beans, lentils, dairy (taken away from your medicine if advised), and other protein-rich foods to support healing and maintain body weight during TB treatment.
  • Limit foods high in tyramine or histamine if advised: The isoniazid component may occasionally interact with foods such as aged cheeses, cured meats, red wine, and certain fish (such as tuna or mackerel), causing flushing, headache, palpitations, or sweating in some people. Your doctor will advise whether you need to avoid these foods.
  • Separate antacid use: If you need aluminum-containing antacids, take them at least 2 hours after your TB medicine because they can reduce the absorption of some components, particularly ethambutol.

Health Queries

Should all four tablets in the Risorine Kit be taken on an empty stomach?

Bayyarapu Mahesh Kumar

Bayyarapu Mahesh Kumar

M Pharmacy

Risorine Kit is a prescription-only combination therapy used for the treatment of tuberculosis, and it must be taken strictly under the guidance of a qualified doctor. You should never self-administer this kit, as the dosing schedule, duration, and clinical monitoring depend entirely on your specific medical condition, body weight, overall treatment plan, and individual health factors. Please consult your prescribing doctor or pharmacist for precise administration instructions, and follow only their recommended regimen.
health query

Have a query?

How Soon It Starts Working

The time required for Risorine Kit to start to work: The time required for Risorine Kit to show its action is not clinically established. The time for which the effects of Risorine Kit last: The duration of action for Risorine Kit is not clinically established.

What if you forget to take Risorine Kit

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.

Storage

•Store Risorine Kit at room temperature, ideally between 15°C and 30°C (59°F to 86°F).

Drug Warnings

  • Expect your urine, sweat, saliva, tears, and sputum to turn a harmless red-orange color due to rifampicin. Soft contact lenses may become permanently stained.
  • Keep all appointments for blood tests and eye examinations so your doctor can monitor your liver function, kidney function (when needed), and eyesight during treatment.
  • Use a reliable non-hormonal contraceptive method, such as condoms, because rifampicin can reduce the effectiveness of hormonal contraceptives, including birth control pills, patches, implants, and vaginal rings.
  • Never skip doses or stop treatment early, even if you feel better. Completing the full course is essential to cure tuberculosis and prevent drug-resistant TB.
  • Tell every doctor, dentist, or pharmacist treating you that you are taking anti-tuberculosis medicines.

verifiedApollotooltip

Risorine Kit can interact with several medications.

  • Rifampicin may reduce the effectiveness of hormonal contraceptives, warfarin, certain heart medicines, antifungal medicines, antivirals, and several other prescription drugs because it increases the breakdown of these medicines in the body.
  • Antacids containing aluminum can reduce the absorption of some components, particularly ethambutol. Take antacids at least 2 hours after your TB medicine.

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verifiedApollotooltip
  • Taking this medicine with heavy or high-fat meals may reduce the absorption of some components.
  • Alcohol should be avoided completely, as it significantly increases the risk of liver damage.
  • Foods rich in tyramine or histamine (such as aged cheeses, cured meats, red wine, and certain fish) may occasionally cause flushing, headache, sweating, or palpitations. This interaction is mainly related to the isoniazid component.

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Habit Forming

No

Therapeutic Class

[ANTI- TUBERCULOSIS]

FAQs

Risorine Kit is used to treat Tuberculosis.
Risorine Kit works by killing the bacteria named Mycobacterium tuberculosis, which causes TB (tuberculosis).
This medication causes a harmless red-orange discoloration of your urine, sweat, saliva, and tears. This is a normal side effect of the medicine passing through your body. If you wear soft contact lenses, they may become permanently stained, so it is best to avoid wearing them during your treatment. Talk to your doctor if you have concerns.
No, you should avoid alcohol completely while taking Risorine Kit. Combining this medicine with alcohol significantly increases the risk of severe liver damage. Talk to your doctor if you need support in avoiding alcohol.
You should take Risorine Kit on an empty stomach, either one hour before a meal or two hours after. This helps your body absorb the medication fully. If you experience severe stomach upset, talk to your doctor.
If you notice any changes in your vision, such as blurred vision or difficulty distinguishing colors, contact your doctor immediately. This can be a sign of a rare but serious side effect affecting your eyes. Talk to your doctor before taking your next dose.
Your doctor may prescribe Vitamin B6 (pyridoxine) to take alongside Risorine Kit. This vitamin helps prevent nerve damage, which can cause numbness, tingling, or burning sensations in your hands and feet. Talk to your doctor to see if this is necessary for you.
No, you must complete the entire course of Risorine Kit exactly as prescribed, even if you feel completely better. Stopping the treatment early can allow the remaining bacteria to multiply and become resistant to medications, making the infection harder to treat. Talk to your doctor if you are struggling with your treatment schedule.
Yes, Risorine Kit can make hormonal birth control methods (such as pills, patches, vaginal rings, or implants) less effective. You should use a non-hormonal backup method of contraception, such as condoms, while taking this medication. Talk to your doctor or pharmacist about the best birth control options for you.
You should watch for signs of liver damage, which include yellowing of your skin or the whites of your eyes, dark-colored urine, pale stools, severe fatigue, loss of appetite, and persistent nausea or vomiting. If you experience any of these symptoms, contact your healthcare provider immediately. Talk to your doctor.
The isoniazid component may interact with foods that contain high amounts of tyramine or histamine, such as aged cheeses, cured meats, red wine, and certain fish. In some people, this may cause flushing, headache, sweating, or a rapid heartbeat. This reaction is uncommon, but your doctor may recommend limiting these foods during treatment. Talk to your doctor or pharmacist if you have concerns.

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Country of origin

India

Manufacturer/Marketer address

Sarkhej-Dholka Road, Bhat, Ahmedabad-382 210, INDIA.
Other Info - RIS0090
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