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  3. RISOFOS 150MG TABLET

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RISOFOS 150MG TABLET, Pack of 1 TABLET
RISOFOS 150MG TABLET, Pack of 1 TABLET
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Written By Veda Maddala , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
RISOFOS 150MG TABLET is used to treat osteoporosis (weak and brittle bones) and Paget’s disease of bone. It contains Risedronic acid which prevents the bones from breaking and keeps them strong. In some cases, this medicine may cause side effects such as headache, nausea, indigestion, stomach pain, cramps or discomfort, constipation, and diarrhoea. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Composition :

RISEDRONIC ACID-150MG

Manufacturer/Marketer :

Cipla Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About RISOFOS 150MG TABLET

RISOFOS 150MG TABLET belongs to the class of medicines called bisphosphonates used to treat or prevent osteoporosis (weak and brittle bones) caused by menopause or taking steroids for a long time. Also, RISOFOS 150MG TABLET is used to treat Paget’s disease of bone. Osteoporosis is a bone disease that weakens and thins bones by decreasing bone density, common in post-menopausal women.  As the density of bones decreases, they weaken and are more likely to break.

RISOFOS 150MG TABLET contains Risedronic acid that works by binding to the bone tightly and preventing the removal of calcium by osteoclasts (a type of bone cell that destroys bone tissue). This prevents osteoclasts from breaking down the bone and keeps the bones strong and minimizes the risk of bones breaking.

Take RISOFOS 150MG TABLET as prescribed by your doctor. You are advised to take RISOFOS 150MG TABLET for as long as your doctor has prescribed it for you based on your medical condition. In some cases, you may experience headache, nausea, indigestion, stomach pain, cramps or discomfort, constipation, diarrhea, pain in the muscles, joints, or bones, feeling of fullness or bloating. Most of these side effects of RISOFOS 150MG TABLET do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to RISOFOS 150MG TABLET, any sugars, or any other medicines, please tell your doctor. Avoid taking RISOFOS 150MG TABLET if you are pregnant or breastfeeding and consult a doctor. RISOFOS 150MG TABLET is not recommended for children below 18 years as the safety and effectiveness were not established. Avoid taking RISOFOS 150MG TABLET if you have hypocalcemia (low calcium levels in the blood) and severe kidney problems. Avoid drinking alcohol as heavy drinking may also cause bone loss. Avoid smoking as it may decrease bone mineral density and increase the risk of fractures. RISOFOS 150MG TABLET may cause osteonecrosis of the jaw (ONJ) in some patients. Therefore, if you experience any problems with teeth or mouth such as loose teeth, swelling or pain, non-healing of sores, or discharge, consult your doctor and dentist as these might be signs of osteonecrosis of the jaw.

Uses of RISOFOS 150MG TABLET

Treatment of Osteoporosis, Paget's disease of the bone.

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Directions for Use

• RISOFOS 150MG TABLET should be taken on an empty stomach, at least 30 minutes before or 2 hours after a meal. Avoid taking RISOFOS 150MG TABLET with milk, as it contains calcium, which may reduce the effect of RISOFOS 150MG TABLET.• It is recommended to take RISOFOS 150MG TABLET once daily or as advised by your doctor.• Swallow RISOFOS 150MG TABLET as a whole with a glass of water while in an upright position to prevent heartburn.• Do not crush, chew, or break it.• Do not lie down for half an hour after taking RISOFOS 150MG TABLET.

Medicinal Benefits

Risedronate (risedronate sodium) helps your bones stay as strong as possible. RISOFOS 150MG TABLET is used to treat osteoporosis and Paget’s disease. In osteoporosis, risedronate slows down the cells that break down bone. This maintains bone density and makes your bones stronger and less likely to break. In Paget's disease of bone, risedronate reduces the abnormal bone turnover that this condition causes. This helps to reduce deformity and pain and makes your bones stronger and less likely to break.

How RISOFOS 150MG TABLET Works

RISOFOS 150MG TABLET contains Risedronic acid that works by binding to the bone tightly and preventing the removal of calcium by osteoclasts (a type of bone cell that destroys bone tissue). This prevents osteoclasts from breaking down the bone and keeps the bones strong and minimizes the risk of bones breaking.

Storage

Keep RISOFOS 150MG TABLET out of reach and sight of children.
Side effects of Risofos 150mg Tablet
Managing back pain as a side effect of medication requires a combination of self-care techniques, lifestyle modifications, and medical interventions. Here are the steps:
  • Talk to your doctor about your back pain and potential medication substitutes or dose changes.
  • Try yoga or Pilates and other mild stretching exercises to increase flexibility and strengthen your back muscles.
  • To lessen the tension on your back, sit and stand upright and maintain proper posture.
  • To alleviate discomfort and minimize inflammation, apply heat or cold packs to the afflicted area.
  • Under your doctor's supervision, think about taking over-the-counter painkillers like acetaminophen or ibuprofen.
  • Make ergonomic adjustments to your workspace and daily activities to reduce strain on your back.
  • To handle tension that could make back pain worse, try stress-reduction methods like deep breathing or meditation.
  • Use pillows and a supportive mattress to keep your spine in the right posture as you sleep.
  • Back discomfort can worsen by bending, twisting, and heavy lifting.
  • Speak with a physical therapist to create a customized training regimen to increase back strength and flexibility.
Here are the steps to manage Joint Pain caused by medication usage:
  • Please inform your doctor about joint pain symptoms, as they may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Your doctor may prescribe common pain relievers if necessary to treat joint discomfort.
  • Maintaining a healthy lifestyle is key to relieving joint discomfort. Regular exercise, such as low-impact sports like walking, cycling, or swimming, should be combined with a well-balanced diet. Aim for 7-8 hours of sleep per night to assist your body in repairing and rebuilding tissue.
  • Applying heat or cold packs to the affected joint can help reduce pain and inflammation.
  • Please track when joint pain occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
  • If your joint pain is severe or prolonged, consult a doctor to rule out any underlying disorders that may require treatment.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
Here are the step-by-step strategies to manage the side effects of "indigestion" caused by medication usage:
  • Take medications with food (if recommended): It can help prevent stomach distress and indigestion.
  • Eat smaller, more frequent meals: Divide daily food intake into smaller, more frequent meals to ease digestion.
  • Avoid trigger foods: Identify and avoid foods that trigger indigestion, such as spicy, fatty, or acidic foods.
  • Stay upright after eating: Sit or stand upright for at least 1-2 hours after eating to prevent stomach acid from flowing into the oesophagus.
  • Avoid carbonated drinks: Avoid drinking carbonated beverages, such as soda or beer, which can worsen indigestion.
  • Manage stress: To alleviate indigestion, engage in stress-reducing activities like deep breathing exercises or meditation.
  • Consult a doctor if needed: If indigestion worsens or persists, consult a healthcare professional to adjust the medication regimen or explore alternative treatments.
Here are the steps to manage angioedema (Swelling Under The Skin) as a side effect of medication:
  • If you experience angioedema, inform your doctor immediately. Treatment can help keep the swelling under control.
  • Seek medical attention if symptoms are severe, such as difficulty breathing or swallowing.
  • Follow your doctor's instructions to manage symptoms, which may include stopping or adjusting the medication that triggered angioedema.
  • Your doctor may also recommend antihistamines, steroids, or other treatments to reduce swelling and inflammation.
  • Make dietary and lifestyle changes as recommended, such as avoiding trigger foods or reducing stress.
  • Monitor your condition closely and track your symptoms to report them to your doctor.
  • Consult your doctor again if symptoms worsen or do not improve or if you experience any new or concerning symptoms.
  • See a doctor or dermatologist to identify and stop the medicine responsible for causing the problem.
  • Your doctor may prescribe antibiotics, steroid creams, or immune system-targeting medications to heal your skin, manage symptoms, and prevent new blisters.
  • Follow your doctor’s advice on how to care for blisters.
  • Limit activities if necessary, as blisters on your hands or feet may affect your mobility.
  • Try not to scratch the affected area and avoid exposure to excessive heat and sun.
  • Wear loose, cotton clothing to avoid irritation of your skin.
  • If you have blisters in your mouth, stick to softer foods and avoid crunchy ones.

What if I have taken an overdose of RISOFOS 150MG TABLET

Take RISOFOS 150MG TABLET only as prescribed by the physician. Avoid exceeding the recommended dose as it could lead to an overdose. Symptoms of overdose may include numbness or tingling around the mouth or in hands or feet, muscle spasms/cramps/twitches, and seizures. If you experience these symptoms or suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

If you are allergic to RISOFOS 150MG TABLET,  or any other medicines, please tell your doctor. Avoid taking RISOFOS 150MG TABLET if you are pregnant or breastfeeding and consult a doctor. RISOFOS 150MG TABLET is not recommended for children below 18 years as the safety and effectiveness were not established. Avoid taking RISOFOS 150MG TABLET if you have hypocalcaemia (low calcium levels in the blood) and severe kidney problems. Avoid drinking alcohol as heavy drinking may also cause bone loss. If you have parathyroid hormone abnormalities, lack of vitamin D, swelling, numbness or pain in the jaw, loose tooth, heavy jaw feeling or had  Barrett’s oesophagus (abnormal change in the cells lining the lower oesophagus), inform your doctor before taking RISOFOS 150MG TABLET. Avoid smoking as it may decrease bone mineral density and increase the risk of fractures. RISOFOS 150MG TABLET may cause osteonecrosis of the jaw (ONJ) in some patients. Therefore, if you experience any problems with teeth or mouth such as loose teeth, swelling or pain, non-healing of sores or discharge, consult your doctor and dentist as these might be signs of osteonecrosis of the jaw. Your doctor may prescribe calcium and vitamin D supplements if you do not take sufficient from your diet.

Drug-Drug Interactions

verifiedApollotooltip
Risedronic acidEtelcalcetide
Severe
Risedronic acidDeferasirox
Severe

Drug-Drug Interactions

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Risedronic acidEtelcalcetide
Severe
How does the drug interact with Risofos 150mg Tablet:
Taking Etelcalcetide with Risofos 150mg Tablet may decrease calcium levels in the blood.

How to manage the interaction:
Co-administration of Risofos 150mg Tablet with Etelcalcetide can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult your doctor immediately if you experience symptoms such as numbness or tingling around the mouth, muscle pain, fits, mental changes (irritability, depression, psychosis), increased pressure on the brain, and irregular heartbeat. Do not stop using any medications without first talking to a doctor.
Risedronic acidDeferasirox
Severe
How does the drug interact with Risofos 150mg Tablet:
Taking Risofos 150mg Tablet (oral form) with Deferasirox can increase the risk of bleeding and ulcers in the stomach.

How to manage the interaction:
Taking Risofos 150mg Tablet with Deferasirox together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, consult your doctor if you experience abdominal pain, bloating, sudden dizziness or lightheadedness, nausea, vomiting (especially with blood), loss of hunger, or black, tarry stools. Do not discontinue any medications without consulting a doctor.
Risedronic acidCimetidine
Severe
How does the drug interact with Risofos 150mg Tablet:
Taking Risofos 150mg Tablet with Cimetidine can increase the blood levels of Risofos 150mg Tablet.

How to manage the interaction:
Although there is a possible interaction between Risofos 150mg Tablet and Cimetidine, you can take these medicines together if prescribed by a doctor. In case you experience any unusual side effects, consult a doctor. Do not discontinue any medications without first consulting your doctor.
Risedronic acidNizatidine
Severe
How does the drug interact with Risofos 150mg Tablet:
Taking Risofos 150mg Tablet with nizatidine can increase the blood levels of Risofos 150mg Tablet.

How to manage the interaction:
There may be a possibility of interaction between Risofos 150mg Tablet and Nizatidine, but it can be taken if prescribed by a doctor. In case you experience any unusual side effects, consult a doctor. Do not stop using any medications without talking to a doctor.
Risedronic acidFamotidine
Severe
How does the drug interact with Risofos 150mg Tablet:
Taking Famotidine with Risofos 150mg Tablet can increase the blood levels of Risofos 150mg Tablet.

How to manage the interaction:
There may be a possibility of interaction between Risofos 150mg Tablet and Famotidine, but it can be taken if prescribed by a doctor. In case you experience any unusual side effects, consult a doctor. Do not stop using any medications without talking to a doctor.
Risedronic acidIbuprofen
Severe
How does the drug interact with Risofos 150mg Tablet:
Taking Risofos 150mg Tablet with ibuprofen can increase the risk of developing kidney problems, gastrointestinal bleeding, and ulcers.

How to manage the interaction:
Co-administration of Risofos 150mg Tablet and Ibuprofen can lead to an interaction but it can be taken if your doctor has advised it. However, consult your doctor if you experience abdominal pain, bloating, sudden dizziness or lightheadedness, nausea, vomiting (especially with blood), loss of appetite, and/or black, tarry stools. Do not discotinue any medications without consulting a doctor.

Drug-Food Interactions

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RISEDRONIC ACID-150MGVitamin B complex foods, Vitamin B12 rich foods
Moderate

Drug-Food Interactions

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RISEDRONIC ACID-150MGVitamin B complex foods, Vitamin B12 rich foods
Moderate
Common Foods to Avoid:
Avocado, Beetroot, Cereals, Cheese, Chicken, Black Beans, Eggs, Clams, Chickpea, Whole Grains, Shellfish, Spinach, Salmon, Red Meat, Oysters, Potatoes, Kidney Beans, Mackerel, Milk, Kale, Tuna, Yogurt, Liver, Low-Fat Milk, Trout, Fortified Breakfast Cereal, Fish, Beef

How to manage the interaction:
Products containing magnesium, aluminum, calcium, iron, and/or other minerals may decrease the blood levels of Risofos 150mg Tablet. If you are on multivitamins, and prescribed with Risofos 150mg Tablet, inform the doctor.

Diet & Lifestyle Advise

  • Include dairy products like milk, yogurt, cheese, or milk-based custard in your diet.
  • Eat daily a serving of broccoli, cabbage, bok choy (Chinese white cabbage), spinach, and other green leafy vegetables.
  • Snack on calcium-rich nuts like Brazil nuts or almonds.
  • Sprinkle sesame seeds over your food, vegetables, and salads. Sesame seeds are high in calcium.
  • Avoid or reduce the intake of caffeine, soft drinks, and alcohol that inhibit calcium absorption.
  • Replace the meat with tofu or tempeh for extra calcium in your food.

Habit Forming

No

Therapeutic Class

BONE ENHANCERS
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Alcohol

Caution

The interaction of alcohol with RISOFOS 150MG TABLET is unknown. Please consult a doctor before consuming alcohol with RISOFOS 150MG TABLET.

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Pregnancy

Caution

RISOFOS 150MG TABLET is a category C pregnancy drug and is given to pregnant women only if the doctor thinks benefits outweigh risks. Please consult a doctor if you are pregnant.

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Breast Feeding

Caution

RISOFOS 150MG TABLET is given to breastfeeding women only if the doctor thinks benefits are greater than risks. Please consult a doctor if you are breastfeeding.

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Driving

Caution

RISOFOS 150MG TABLET usually does not affect your ability to drive or operate machinery.

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Liver

Caution

Take RISOFOS 150MG TABLET with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Take RISOFOS 150MG TABLET with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required. Avoid taking RISOFOS 150MG TABLET if you have severe kidney problems.

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Children

Unsafe

RISOFOS 150MG TABLET is not recommended for children below 18 years as the safety and effectiveness were not established.

FAQs

RISOFOS 150MG TABLET is used to treat osteoporosis (weak and brittle bones) and Paget's disease of bone.

RISOFOS 150MG TABLET contains Risedronic acid used to treat osteoporosis and Paget’s disease. In osteoporosis, risedronate slows down the cells that break down bone. This maintains bone density and makes your bones stronger and less likely to break. In Paget's disease of bone, risedronate reduces the abnormal bone turnover that this condition causes. This helps to reduce deformity and pain and makes your bones stronger and less likely to break.

You are not recommended to take RISOFOS 150MG TABLET if you have hypocalcemia (low levels of calcium in the blood) as it may worsen the condition. However, the levels of calcium and vitamin D may be checked before starting treatment with RISOFOS 150MG TABLET.

RISOFOS 150MG TABLET may cause osteonecrosis (bone damage) of the jaw. Therefore, to prevent such condition, maintain good oral hygiene and have regular dental check-ups while taking RISOFOS 150MG TABLET. Also, is you wear dentures, make sure they fit properly. However, if you experience any problems with teeth or mouth such as loose teeth, swelling or pain, non-healing of sores or discharge, consult your doctor and dentist as these might be signs of osteonecrosis of the jaw.

You are not recommended to take RISOFOS 150MG TABLET with milk as it contains calcium and may reduce the effect of RISOFOS 150MG TABLET. Therefore, take RISOFOS 150MG TABLET with a glass of water 30 minutes before food for effective results.

You are not recommended to take RISOFOS 150MG TABLET with antacids containing magnesium and aluminium as co-administration of these two medicines at the same time may reduce the effectiveness of RISOFOS 150MG TABLET. You may take antacids, calcium or iron supplements after 30 minutes of taking RISOFOS 150MG TABLET. However, please consult a doctor before taking RISOFOS 150MG TABLET with other medicines.

RISOFOS 150MG TABLET may rarely cause unusual fracture of the thigh bone, especially in patients taking RISOFOS 150MG TABLET for a prolonged duration. However, if you experience weakness, pain or discomfort in the thigh, groin or hip, please consult a doctor as these might be early signs of a possible thigh bone fracture.

Take RISOFOS 150MG TABLET in the morning or at least 30 minutes before eating or 2 hours after food as prescribed by your doctor. Swallow it as a whole with a glass of water while in an upright position to prevent heartburn. Do not break, crush or chew it. Do not lie down for half an hour after taking RISOFOS 150MG TABLET.

You should not lie down after taking RISOFOS 150MG TABLET because it can cause irritation or ulcers in esophagus (the tube that connects your mouth to your stomach). Remaining upright helps ensure RISOFOS 150MG TABLET reaches your stomach quickly and reduces the risk of esophageal irritation.

Yes, RISOFOS 150MG TABLET can cause hair loss as a side effect, although it is not very common. If you experience hair loss while taking RISOFOS 150MG TABLET, please consult your doctor.

RISOFOS 150MG TABLET is prescribed by a doctor only if the benefits outweighs the risk. Therefore, please consult your doctor if you are pregnant.

Ensure your diet is rich in calcium and vitamin D, include dairy products, leafy greens, nuts, and fortified foods. Engage in regular weight-bearing exercises like walking, jogging, or dancing to strengthen your bone. Drink plenty of water throughout the day to stay hydrated. Avoid or reduce the intake of caffeine, soft drinks, and alcohol that inhibit calcium absorption.

The common side effects of RISOFOS 150MG TABLET are headache, nausea, indigestion, stomach pain, cramps or discomfort, constipation, diarrhoea, pain in the muscles, joints, or bones, feeling of fullness or bloating. If any of these side effects persists or worsen, please consult your doctor.

Country of origin

India

Manufacturer/Marketer address

Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013
Other Info - RIS0043

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Author Details

Veda MaddalaDoctor badge

Written By

Veda Maddala

M Pharmacy

Bayyarapu Mahesh KumarDoctor badge

Reviewed By

Bayyarapu Mahesh Kumar

M Pharmacy

Last Updated

Jul 18, 2025 | 6:47 AM IST

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Reference

  1. https://www.medicines.org.uk/emc/files/pil.3029.pdf
  2. https://www.nhs.uk/medicines/risedronate/
  3. https://www.drugs.com/mtm/risedronate.html

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