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Written By ,
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Rifagrap-M Tablet 10's is used to treat bacterial infections, particularly those affecting the gastrointestinal tract, such as intestinal and parasitic infections. It eliminates harmful bacteria and prevents their growth. Common side effects may include nausea, diarrhea, abdominal pain, headache, dizziness, or a metallic taste.

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Manufacturer/Marketer :

Grapple Life Sciences Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Rifagrap-M Tablet 10's

Rifagrap-M Tablet 10's is an antibiotic combination used to treat bacterial and gastrointestinal infections (including traveller's diarrhoea and irritable bowel syndrome). Gastrointestinal infections are conditions caused by harmful microorganisms, such as bacteria, viruses, or parasites, that affect the digestive system. They often lead to symptoms like nausea, vomiting, diarrhoea, and abdominal pain.

Rifagrap-M Tablet 10's is a combination of Metronidazole and Rifaximin. Metronidazole is an antimicrobial agent that kills bacteria and protozoa by disrupting their DNA. Rifaximin is a non-absorbable antibiotic that works directly in the gut to inhibit bacterial growth. Together, they help relieve symptoms, prevent complications, and promote intestinal health.

Give Rifagrap-M Tablet 10's to your child as prescribed by the doctor. It can cause side effects like nausea, diarrhea, abdominal pain, headache, dizziness, or a metallic taste. These effects are usually temporary and do not require medical attention. However, if they continue or worsen, see your doctor for advice.

If your child is allergic to other medicines, please tell the doctor. Rifagrap-M Tablet 10's should be used only in doses prescribed by a doctor for children. It is recommended that you complete the entire course of Rifagrap-M Tablet 10's as prescribed by the doctor, even if your child feels better after a few days. Rifagrap-M Tablet 10's is used with caution in children with heart, liver/kidney disorder, colitis, blood dyscrasias, or neurologic toxicity.

Uses of Rifagrap-M Tablet 10's

Rifagrap-M Tablet 10's is used in the treatment of Traveller's Diarrhoea, Small Intestinal Bacterial Overgrowth, and Irritable Bowel Syndrome (IBS) in children. The detailed uses of Rifagrap-M Tablet 10's are as follows:<br/>• Traveller’s Diarrhoea (TD): Rifagrap-M Tablet 10's effectively manages symptoms of traveller's diarrhoea by combating bacterial and protozoal infections that cause gastrointestinal distress.<br/>• Treatment of Small Intestinal Bacterial Overgrowth: Rifagrap-M Tablet 10's helps reduce excessive bacterial growth in the small intestine.<br/>• Irritable Bowel Syndrome: Rifagrap-M Tablet 10's may help alleviate symptoms of IBS, such as abdominal pain, bloating, and diarrhea, by targeting gut bacteria and reducing inflammation.<br/>

Directions for Use

• Rifagrap-M Tablet 10's can be taken with or without food.• Follow your doctor's instructions on the dosage and timing of this medication.• Administer the advised dose to the child using the measuring cup/measuring spoon/dropper.• Shake the bottle well before use.

Medicinal Benefits

Rifagrap-M Tablet 10'scombines the benefits of two antibiotics to treat a variety of gastrointestinal conditions. Metronidazole targets bacterial infections and helps treat conditions like gut infections, abscesses, and certain parasitic infections. Rifaximin, a non-absorbable antibiotic, is effective against bacterial overgrowth in the intestines and helps manage conditions like irritable bowel syndrome (IBS) and hepatic encephalopathy. Together, they support gut health, reduce bacterial infections, and improve overall digestive function.

How Rifagrap-M Tablet 10's Works

Rifagrap-M Tablet 10's is a combination of Metronidazole and Rifaximin. Metronidazole is an antimicrobial agent that kills bacteria and protozoa by disrupting their DNA. Rifaximin is a non-absorbable antibiotic that works directly in the gut to inhibit bacterial growth. Together, they help relieve symptoms, prevent complications, and promote intestinal health.

Storage

• Store in a cool and dry place away from sunlight.
• Keep Rifagrap-M Tablet 10's out of the sight and reach of children.
• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

What if I have taken an overdose of Rifagrap-M Tablet 10's

Give Rifagrap-M Tablet 10's only as advised by the physician. Do not exceed the prescribed dose, as it might cause an overdose. If you suspect you have given an overdose, seek immediate medical attention.

Drug Warnings

Avoid giving Rifagrap-M Tablet 10's to your child if she/he is allergic to it. Keep your Pediatrician informed about your child’s health condition, including their previous medications and medical history, to rule out any side effects/interactions. Before administration, inform the pediatrician about all the OTC medicines, including other vitamin supplements that your child is taking. It is advised not to give more than the prescribed dose of medicine. Also, inform your doctor if your child has a history of heart, liver/kidney disorder, colitis, blood dyscrasias, or neurologic toxicity before administration. 

Drug-Drug Interactions

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Critical

Drug-Drug Interactions

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How does the drug interact with Rifagrap-m Tab:
Coadministration of Disulfiram with Rifagrap-m Tab can increase the risk of side effects.

How to manage the interaction:
Taking Rifagrap-m Tab and Disulfiram together is generally avoided as it can lead to an interaction, it can be taken if advised by your doctor. However, if you experience sudden dizziness, confusion, weakness, shortness of breath, or palpitations, contact your doctor. Do not discontinue any medications without consulting a doctor.
Critical
How does the drug interact with Rifagrap-m Tab:
Drinking alcohol while taking Rifagrap-m Tab can increase the risk or severity of side effects.

How to manage the interaction:
Taking Rifagrap-m Tab with Ethanol is avoided as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience flushing, throbbing in head and neck, throbbing headache, difficulty breathing, nausea, vomiting, sweating, thirst, chest pain, rapid heartbeat, palpitation, low blood pressure, dizziness, lightheadedness, blurred vision, and confusion, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
MetronidazoleAmprenavir
Critical
How does the drug interact with Rifagrap-m Tab:
Co-administration of Amprenavir with Rifagrap-m Tab can increase the risk or severity of side effects.

How to manage the interaction:
Taking Rifagrap-m Tab with Amprenavir is generally avoided as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience throbbing in the head and neck, throbbing headache, difficulty breathing, nausea, vomiting, sweating, thirst, chest pain, rapid heartbeat, palpitation, low blood pressure, dizziness, lightheadedness, blurred vision, and confusion, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
RifaximinCholera, live attenuated
Severe
How does the drug interact with Rifagrap-m Tab:
Coadministration of cholera vaccine with Rifagrap-m Tab may reduce the effect of the cholera vaccine.

How to manage the interaction:
Taking Rfaximine and Cholera, live attenuated together can result in an interaction, but it can be taken together if prescribed by a doctor. It is recommended to take the cholera vaccine at least 14 days following the last dosage of Rifagrap-m Tab. Do not discontinue any medicine without consulting a doctor.
How does the drug interact with Rifagrap-m Tab:
Coadministration of Rifagrap-m Tab with warfarin can increase the risk of bleeding.

How to manage the interaction:
There is a possible interaction between Rifagrap-m Tab and warfarin, but they can be taken together if a doctor has prescribed them. Consult a doctor if experience unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness. Do not stop using any medications without talking to a doctor.
How does the drug interact with Rifagrap-m Tab:
Coadministration of Rifagrap-m Tab with mebendazole may increase the risk or severity of side effects.

How to manage the interaction:
Although there is a possible interaction between Rifagrap-m Tab and mebendazole, they can be taken together if your doctor has prescribed them. However, if you experience any unusual symptoms like fever, body ache, painful red rash, cough, peeling of the skin, or Drooling, contact a doctor immediately. Do not stop using any medications without talking to a doctor.
How does the drug interact with Rifagrap-m Tab:
Coadministration of Busulfan and Rifagrap-m Tab may increase the risk of side effects.

How to manage the interaction:
Taking Rifagrap-m Tab and Busulfan together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience unusual bruising or bleeding, fever, diarrhea, sore throat, muscle aches, shortness of breath, or burning during urination, contact a doctor immediately. Do not discontinue the medication without a doctor's advice.
How does the drug interact with Rifagrap-m Tab:
Co-administration of Fluconazole together with Rifagrap-m Tab can increase the risk of an irregular heart rhythm.

How to manage the interaction:
-Taking Rifagrap-m Tab with Fluconazole together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any symptoms such as dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Avoid spicy or greasy foods that could upset the stomach.
  • Serve smaller, more frequent meals to help prevent stomach discomfort.
  • Limit foods high in fiber if the child has diarrhea to avoid worsening symptoms.
  • Include probiotics to support healthy digestion.
  • Avoid sugary drinks and junk food, as these can worsen stomach issues or irritate the gut.

Habit Forming

No

Therapeutic Class

ANTIBIOTICS
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Alcohol

Not applicable

-

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Pregnancy

Not applicable

-

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Breast Feeding

Not applicable

-

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Driving

Not applicable

-

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Liver

Caution

If your child is suffering from liver disease, inform your doctor before using Rifagrap-M Tablet 10's.

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Kidney

Caution

If your child is suffering from kidney disease, inform your doctor before using Rifagrap-M Tablet 10's.

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Children

Safe if prescribed

Rifagrap-M Tablet 10's should be used for children in dose and duration as advised by the doctor.

Have a query?

FAQs

Rifagrap-M Tablet 10's is an antibiotic used to treat bacterial infections, particularly those affecting the gastrointestinal tract, such as traveler's diarrhea, Small Intestinal Bacterial Overgrowth and irritable bowel syndrome.

Rifagrap-M Tablet 10's is a combination of Metronidazole and Rifaximin. Metronidazole is an antimicrobial agent that kills bacteria and protozoa by disrupting their DNA. Rifaximin is a non-absorbable antibiotic that works directly in the gut to inhibit bacterial growth. Together, they help relieve symptoms, prevent complications, and promote intestinal health.

Consult your doctor before giving Rifagrap-M Tablet 10's with other antibiotics to avoid drug interactions.

Giving higher amounts than prescribed to children is ineffective and may lead to negative effects. To ensure safe and effective use, follow your doctor's dosage instructions.

You are not recommended to stop giving Rifagrap-M Tablet 10's to your child without consulting the doctor as it may worsen the condition or cause recurring symptoms. Therefore, use Rifagrap-M Tablet 10's for as long as your doctor has prescribed it, and if your child experiences any difficulty while taking Rifagrap-M Tablet 10's, please consult your doctor.

Common side effects include nausea, headache, dizziness, metallic taste, and diarrhea. If these side effects persist or worsen, seek immediate medical attention.

Country of origin

India

Manufacturer/Marketer address

Scf 1025, 1St & 2nd Floor, Motor Market, Manimajra, Chandigarh 160101, India
Other Info - RIF0287

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