Rifafrez 400 mg Tablet 10's is used to treat infectious traveller's diarrhoea, hepatic encephalopathy and irritable bowel syndrome with diarrhoea (IBS-D). Traveller’s diarrhoea is an infection in which there is a passage of unformed stools. Hepatic encephalopathy causes loss of brain function when a damaged liver is unable to remove toxins from the blood. Irritable bowel syndrome is a condition which affects the large intestine.

Rifafrez 400 mg Tablet 10's contains Rifaximin, which works by acting on the bowel and preventing the spread of infections caused by the loss of beneficial gut bacteria. 

Common side effects of Rifafrez 400 mg Tablet 10's include headache, leg swelling, nausea, dizziness, fatigue, ascites (excess fluid buildup in the abdomen), and increased liver enzymes (ALT). Most of these side effects do not require medical attention and will resolve gradually over time. However, talk to your doctor if you experience these side effects persistently.

Take Rifafrez 400 mg Tablet 10's by mouth with or without food as directed by your doctor. The dosage is based on your medical condition and response to treatment. To help you remember, take it at the same time each day. Do not chew, crush, or break the medicine.

Before starting Rifafrez 400 mg Tablet 10's, please inform your doctor if you have any allergies (to any antibiotic) or kidney or liver problems. Do not take Rifafrez 400 mg Tablet 10's for more than 3 days unless your doctor prescribes it. Inform your doctor if you are pregnant or breastfeeding without talking to your doctor. Rifafrez 400 mg Tablet 10's is not recommended for children as efficacy and safety have not been established.

Rifafrez 400 mg Tablet 10's is used in the treatment of travelles' diarrhoea, liver encephalopathy, and irritable bowel syndrome due to diarrhoea. The detailed uses of Rifafrez 400 mg Tablet 10's are as follows:

• Diarrhoea in Travellers: Rifafrez 400 mg Tablet 10's is frequently used to treat patients' diarrhoea brought on by non-invasive strains of Escherichia coli when they are visiting places with contaminated food or water.
• Irritable Bowel Syndrome (IBS): By treating intestinal bacterial overgrowth, Rifafrez 400 mg Tablet 10's can help reduce IBS symptoms, especially those with diarrhoea as the predominant symptom.
• Simple Infections: Rifafrez 400 mg Tablet 10's works well for treating simple gastrointestinal infections that might not be improving with other antibiotics.
• Complications Associated with Liver Disease: By reducing the amount of ammonia-producing bacteria in the gut, this medication helps treat hepatic encephalopathy. This condition can develop in people with liver disease.

• Take Rifafrez 400 mg Tablet 10's with or without food as advised by your doctor. • It is advised to take Rifafrez 400 mg Tablet 10's three times daily; however, follow your doctor’s recommendation regarding the dosage and duration. • Swallow Rifafrez 400 mg Tablet 10's as a whole with a glass of water. • Do not crush, chew or break it.

• Rifafrez 400 mg Tablet 10's is used to treat traveller’s diarrhoea caused by noninvasive strains of E.coli.
• Rifafrez 400 mg Tablet 10's is a broad-spectrum antibiotic that is effective against gram-positive and gram-negative bacteria, aerobic and anaerobic bacteria, and ammonia-producing bacteria.
• This medicine is a gastrointestinal-selective antibiotic with a broad spectrum of antimicrobial activity.
• Rifafrez 400 mg Tablet 10's is bactericidal in nature and works by killing the bacteria that cause infections. Thus, it helps in treating and preventing the spread of infections.
• Thus, Rifafrez 400 mg Tablet 10's helps in relieving abdominal pain and diarrhoea.
• Rifafrez 400 mg Tablet 10's should not be used in patients with diarrhoea complicated by fever or blood in the stool and diarrhoea due to pathogens other than Escherichia coli (E.coli).

• Do not take Rifafrez 400 mg Tablet 10's if you are allergic to any of its contents, if you have a fever, blood in stools, passed 8 or more unformed stools in the last 24 hours, constipation, vomiting, and abdominal pain caused by blockage of the bowel.
• Talk to your doctor if your condition does not improve, symptoms continue or re-appear even after taking Rifafrez 400 mg Tablet 10's for 3 days.
• Do not take Rifafrez 400 mg Tablet 10's for more than 3 days unless prescribed; if there is no symptomatic improvement, consult your doctor.
• Avoid taking Rifafrez 400 mg Tablet 10's if you are pregnant or breastfeeding; talk to your doctor; he/she may prescribe you with alternate medicine.
• Rifafrez 400 mg Tablet 10's is not recommended for children below 12 years of age as the efficacy and safety have not been established.
• Patients with liver complications should avoid taking Rifafrez 400 mg Tablet 10's or consult a doctor before using Rifafrez 400 mg Tablet 10's.
• Monitor bleeding time parameters like INR and prothrombin time while using Rifafrez 400 mg Tablet 10's.