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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Rifacept Kid-3 Tablet is an anti-tuberculosis medicine used to treat and prevent tuberculosis in children. This is a combination medicine which works by inhibiting the production of certain enzymes that are required for bacterial cell wall formation. Common side effects include muscle/joint pain, nausea, vomiting, rash, dark-coloured urine, weakness, dry mouth, stomach pain, and upset stomach. If your child experiences any of these side effects, it's important to consult a healthcare provider to ensure proper care.

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Manufacturer/Marketer :

Concept Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Rifacept Kid-3 Tablet

Rifacept Kid-3 Tablet belongs to the group of anti-tuberculosis drugs, primarily used to treat and prevent tuberculosis. Tuberculosis is an infectious disease that mainly affects the lungs but can also spread to other body parts such as the kidneys, brain, spine, and bone marrow.

Rifacept Kid-3 Tablet combines four drugs: Isoniazid, Pyrazinamide, Pyridoxine hydrochloride (vitamin B6), and Rifampicin. Isoniazid inhibits the biosynthesis of mycolic acid, which is the major component of the bacterial cell wall. Pyrazinamide is an antibiotic that works by stopping the growth of bacteria that cause tuberculosis. Pyridoxine hydrochloride treats nerve damage (neuritis) caused by tuberculosis. Rifampicin inhibits DNA-dependent RNA polymerase activity in the bacteria.

Rifacept Kid-3 Tablet is for paediatric use only. Give Rifacept Kid-3 Tablet to children as advised by the doctor. Rifacept Kid-3 Tablet may cause some common side effects such as muscle/joint pain, nausea, vomiting, rash, dark-coloured urine, weakness, dry mouth, stomach pain, and upset stomach. These side effects are not familiar to everyone and vary individually. If you notice any side effects that are not manageable, please consult your doctor.

Before using the Rifacept Kid-3 Tablet , please inform your doctor of your children's or caregiver's medical conditions, sensitivities, and all drugs they are taking. Continue using Rifacept Kid-3 Tablet for as long as your doctor has prescribed to treat your child's illness effectively. Do not use any other medications or supplements while using Rifacept Kid-3 Tablet unless recommended by the doctor.

Uses of Rifacept Kid-3 Tablet

Rifacept Kid-3 Tablet is used to treat and prevent tuberculosis (TB) in children. The detailed uses of Rifacept Kid-3 Tablet are as follows:<br/>• Treating Active TB: Rifacept Kid-3 Tablet helps treat TB infections in the lungs and other parts of the body in children.<br/>• Preventing TB: It is used to stop latent TB from turning into active TB in children who may have been exposed to it.<br/>• For High-Risk Children: Rifacept Kid-3 Tablet is given to children at high risk of developing TB, such as those with weakened immune systems.<br/>• Combination Therapy: The combination of Isoniazid, Pyrazinamide, Pyridoxine hydrochloride (Vitamin B6), and Rifampicin works together to kill the bacteria causing TB.<br/>

Directions for Use

  • Dissolve the tablet in the prescribed amount of water (usually a teaspoonful).
  • Ensure the tablet is completely dissolved or dispersed in the water.
  • Give the prepared solution to your child as directed by the doctor. Ensure your child drinks the solution after it is fully dispersed.
  • Do not allow the child to crush, chew, or swallow the tablet whole.

Medicinal Benefits

Rifacept Kid-3 Tablet contains a combination of Rifampicin, Isoniazid, Pyrazinamide, and Pyridoxine Hydrochloride, which are used to treat and prevent tuberculosis (TB). These medications work together to kill the bacteria causing TB and help stop its spread. Rifampicin and Isoniazid target the bacteria, while Pyrazinamide helps enhance the effectiveness of the other two. Pyridoxine is included to prevent nerve damage that Isoniazid could cause. This combination therapy helps manage the infection, reduce symptoms, and prevent the recurrence of TB.

How Rifacept Kid-3 Tablet Works

Rifacept Kid-3 Tablet is a combination of four drugs: Isoniazid, Pyrazinamide, Pyridoxine hydrochloride (vitamin B6), and Rifampicin. Isoniazid inhibits the biosynthesis of mycolic acid, which is the major component of the bacterial cell wall. Pyrazinamide is an antibiotic that works by stopping the growth of bacteria that cause tuberculosis. Pyridoxine hydrochloride treats nerve damage (neuritis) caused by tuberculosis. Rifampicin inhibits DNA-dependent RNA polymerase activity in the bacteria.

Storage

• Store in a cool and dry place away from sunlight.
• Keep out of sight and reach of children.
• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Rifacept Kid-3 Tablet
  • If you have excess nerve pain and numbness, soak in Epsom salt and warm water. This can help ease the pain and associated discomfort.
  • Use compression socks and make sure to rest for a while to get relief from pain.
  • Avoid smoking and intake of alcohol or fluids that aggravate the pain.
  • Massage your feet or affected area often to get relief from pain. Take the medication prescribed by your doctor without fail.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
Here are the step-by-step strategies to manage the side effects of " Muscle Pain" caused by medication usage:
  • Report to Your Doctor: Inform your doctor about the muscle pain, as they may need to adjust your medication.
  • Stretch Regularly: Gentle stretching can help relieve muscle pain and stiffness.
  • Stay Hydrated: Adequate water intake supports muscle health by removing harmful substances and maintaining proper muscle function.
  • Warm or Cold Compresses: Apply cold or warm compresses to the affected area to reduce pain and inflammation.
  • Rest and Relaxation: Adequate rest helps alleviate muscle strain, while relaxation techniques like deep breathing and meditation can soothe muscle tightness, calm the mind, and promote relief from discomfort.
  • Gentle Exercise: Participate in low-impact activities, such as yoga or short walks, to improve flexibility, reduce muscle tension, and alleviate discomfort.
  • Consult a physician: If your symptoms don't improve or get worse, go to the doctor for help and guidance.
Managing Medication-Triggered malaise (Feeling Unwell): A Step-by-Step Guide:
  • If you experience persistent or severe malaise (a general feeling of discomfort, illness, or unease) after taking medication, seek medical attention immediately.
  • Inform your doctor about the medication you're taking and the symptoms you're experiencing.
  • Your treatment plan may be modified, which may include adjusting the dosage, substituting with an alternative medication, or discontinuing the medication. Additionally, certain lifestyle changes may be recommended to help manage symptoms.
  • To manage malaise symptoms, follow your doctor's advice, such as getting plenty of rest, staying hydrated, and practicing stress-reducing techniques.
  • Track your symptoms regularly and report any changes or concerns to your healthcare provider to ensure the malaise is managed effectively.

What if I have taken an overdose of Rifacept Kid-3 Tablet

If the child accidentally takes too much medicine, contact a healthcare provider or call emergency services immediately. Overdose symptoms may include unusual tiredness, confusion, or changes in behaviour. It's important to act quickly and follow the advice of medical professionals.

Drug Warnings

Rifacept Kid-3 Tablet should be used only if prescribed by the doctor. The presence of other medical problems or the use of other medications may affect the use of this medicine. Rifacept Kid-3 Tablet is not recommended for those hypersensitive to any substance in Rifacept Kid-3 Tablet . So, before using Rifacept Kid-3 Tablet , let your doctor know about all your children's medical conditions, sensitivities, and all medications, including supplements used. Do not give more than the prescribed dose.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Rifacept Kid-3 Tablet:
Taking darunavir with Rifacept Kid-3 Tablet can decrease the blood levels of darunavir, which may make the medication less effective.

How to manage the interaction:
Although there is an interaction between darunavir and Rifacept Kid-3 Tablet, they can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Rifacept Kid-3 Tablet:
Taking Voriconazole with Rifacept Kid-3 Tablet can increase blood level of Voriconazole.

How to manage the interaction:
Although there is an interaction between Voriconazole with Rifacept Kid-3 Tablet, it can be taken if prescribed by a doctor. However, if you experience any unusual symptoms contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
RifampicinSaquinavir
Critical
How does the drug interact with Rifacept Kid-3 Tablet:
Taking saquinavir with Rifacept Kid-3 Tablet can increase the risk or severity of side effects.

How to manage the interaction:
Although there is an interaction between pyrazinamide and Rifacept Kid-3 Tablet, they can be taken together if prescribed by a doctor. However, if you experience fever, stomach pain, less desire to eat, nausea, yellowing of the skin or eyes, or dark urine, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Rifacept Kid-3 Tablet:
When ranolazine is taken with Rifacept Kid-3 Tablet, it can reduce the blood levels and effects of ranolazine.

How to manage the interaction:
Although there is an interaction between ranolazine and Rifacept Kid-3 Tablet, they can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Rifacept Kid-3 Tablet:
When Indinavir is taken with Rifacept Kid-3 Tablet, it can reduce the blood levels and effects of Indinavir.

How to manage the interaction:
Although there is an interaction between indinavir and Rifacept Kid-3 Tablet, they can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Rifacept Kid-3 Tablet:
Taking pirfenidone with Rifacept Kid-3 Tablet can reduce the levels and effects of pirfenidone

How to manage the interaction:
Although there is an interaction between pirfenidone and Rifacept Kid-3 Tablet, they can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Rifacept Kid-3 Tablet:
When Lovastatin is taken with Rifacept Kid-3 Tablet, can increase the risk of myopathy (muscles problems), including rhabdomyolysis (a condition that causes your muscles to break down, which leads to muscle death).

How to manage the interaction:
Taking Rifacept Kid-3 Tablet with Lovastatin is not recommended but can be taken if a doctor has prescribed it.
IsoniazidLomitapide
Critical
How does the drug interact with Rifacept Kid-3 Tablet:
When Lomitapide is taken with Rifacept Kid-3 Tablet, Rifacept Kid-3 Tablet may increase the blood levels of lomitapide which leads to side effects.

How to manage the interaction:
Taking Rifacept Kid-3 Tablet with Lomitapide is not recommended but can be taken if prescribed by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, exhaustion, nausea, vomiting, dark urine, light stools, and skin or eye yellowing, decreased hunger, consult the doctor.
How does the drug interact with Rifacept Kid-3 Tablet:
When Rifacept Kid-3 Tablet is taken with Regorafenib, it can increase the levels of Regorafenib leading to side effects.

How to manage the interaction:
Taking Regorafenib with Rifacept Kid-3 Tablet is not recommended, it taken can be taken if prescribed by the doctor.
How does the drug interact with Rifacept Kid-3 Tablet:
Co-administration of Teriflunomide with Rifacept Kid-3 Tablet may increase the risk or severity of liver damage.

How to manage the interaction:
Although taking Teriflunomide and Rifacept Kid-3 Tablet together can evidently cause an interaction, it can be taken if a doctor has suggested it. If you have any of these symptoms, it's important to contact your doctor immediately: fever, chills, joint pain, swelling, bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark-colored urine, or bleeding. Do not stop using any medications without a doctor's advice. Do not discontinue the medication without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Alcohol can increase the risk of liver damage. To protect your liver, completely avoid alcohol during treatment.
  • Some foods, especially those high in tyramine (like aged cheese, cured meats, and certain fish), can cause adverse reactions when combined with Isoniazid. Be mindful of what you eat and follow your doctor's advice.
  • A well-balanced diet is key to boosting your immune system and helping your body recover. Focus on fruits, vegetables, whole grains, and lean proteins to stay healthy.
  • Drink plenty of water throughout the day. This helps your kidneys work well and supports overall health during your treatment. Since these medications can affect liver function, make sure to have regular liver function tests as recommended by your doctor.
  • Rifampicin can make your skin more sensitive to sunlight. Therefore, you should wear sunscreen and protective clothing and avoid prolonged sun exposure.
  • To prevent drug resistance and ensure the medication works effectively, take the full course as prescribed by your doctor.
  • Before changing your diet or lifestyle, always check with your doctor. They will guide you on what's best for your health during treatment.

Habit Forming

No

Therapeutic Class

ANTI- TUBERCULOSIS
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Alcohol

Not applicable

It is intended for Children.

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Pregnancy

Not applicable

It is intended for Children.

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Breast Feeding

Not applicable

It is intended for Children.

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Driving

Not applicable

It is intended for Children.

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Liver

Caution

Please inform your doctor if your child has a history of Liver diseases. Your doctor will weigh the benefits and potential risks before prescribing Rifacept Kid-3 Tablet .

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Kidney

Caution

Please inform your doctor if your child has a history of kidney diseases. Your doctor will weigh the benefits and potential risks before prescribing Rifacept Kid-3 Tablet .

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Children

Safe if prescribed

Rifacept Kid-3 Tablet is safe for children if prescribed by a doctor. The dose and duration may vary depending on the age and severity of the infection.

Have a query?

FAQs

Rifacept Kid-3 Tablet belongs to the group of medicines called anti-tuberculosis drugs, which are primarily used to treat and prevent tuberculosis.

Rifacept Kid-3 Tablet contains Isoniazid, Pyrazinamide, Pyridoxine hydrochloride (vitamin B6), and Rifampicin. It interferes with the growth of tuberculosis-causing bacteria and kills them. Thus, Rifacept Kid-3 Tablet effectively treats TB (tuberculosis).

Rifacept Kid-3 Tablet may cause discolouration of teeth, sweat, urine, sputum (phlegm), saliva, or tears. The colour in tears may last for some time even after you stop taking Rifacept Kid-3 Tablet . Do not worry, as it is a common side-effect of Rifacept Kid-3 Tablet .

Common side effects may include muscle/joint pain, nausea, vomiting, rash, dark-coloured urine, weakness, dry mouth, stomach pain, and upset stomach. If these side effects become severe or persistent, consult your child’s doctor.

If you miss a dose, give it as soon as you remember, unless it’s almost time for the next dose. Never double the dose to make up for a missed one.

Yes, Rifacept Kid-3 Tablet can be taken with or without food. If your child experiences stomach discomfort, it may help to give them food.

The length of treatment will depend on your child’s condition. It’s important to complete the course as the doctor prescribes to ensure the infection is fully treated.

If your child vomits immediately after taking Rifacept Kid-3 Tablet , give the same dose again. If vomiting occurs after that time, skip the missed dose and continue with the next scheduled dose.

Country of origin

INDIA

Manufacturer/Marketer address

Plot no: 492, Viduthalai Nagar Extension Near JD Mahal, Pallavaram Thuraipakam Road S.Kulathur,Kovilambakkam, Chennai - 600 117
Other Info - RIF0017

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