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Rifacept 3 Tablet 10's is used to treat and prevent tuberculosis. It works by stopping the growth of bacteria that cause tuberculosis. In some cases, this medicine may cause side effects such as muscle/joint pain, nausea, vomiting, rash, dark-coloured urine, weakness, dry mouth, stomach pain, and upset stomach. Before taking this medicine, inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Manufacturer/Marketer :

Concept Pharmaceuticals Ltd

Consume Type :

Oral

Expires on or after :

Dec-28

Return Policy :

Not Returnable

About Rifacept 3 Tablet 10's

Rifacept 3 Tablet 10's is a combination prescription medicine used to treat active tuberculosis (TB). It contains four active components that work together to kill the bacteria causing the infection and prevent them from spreading. Because tuberculosis is a highly resilient bacterial infection, this multi-drug combination is essential for targeting the bacteria at different stages of growth.

For this medicine to be fully effective, you must take it with absolute consistency, exactly as prescribed by your doctor. It is typically taken once daily on an empty stomach, either 1 hour before or 2 hours after a meal, as food can significantly reduce how well your body absorbs the active ingredients. While undergoing treatment, making specific lifestyle adjustments, such as avoiding alcohol completely, is vital to protect your body during recovery.

Common side effects of Rifacept 3 Tablet 10's include a harmless red or orange discolouration of your urine, sweat, and saliva, as well as mild nausea or loss of appetite. However, you must contact your doctor immediately if you experience signs of liver damage, such as persistent abdominal pain, dark urine, or yellowing of your eyes and skin. Regular blood tests will be scheduled by your healthcare provider to monitor your body's response and safety throughout the course of treatment.

Before starting Rifacept 3 Tablet 10's, it is important to discuss your complete medical history with your doctor. Do not take this if you have severe liver disease, acute gout, or if you have previously experienced severe allergic reactions to any of the active components in this medicine. People with diabetes, kidney disease, or a history of nerve pain (neuropathy) require careful monitoring while taking this medication.

This medication can interact with several other substances, including blood thinners, seizure medications, and hormonal birth control, making them less effective or increasing the risk of side effects. Avoid alcohol entirely during your treatment, as it drastically increases the strain on your liver. If you are pregnant, breastfeeding, or are caring for an elderly patient, consult your doctor to discuss the risks and benefits before starting therapy.

Uses of Rifacept 3 Tablet 10's

Rifacept 3 Tablet 10's is prescribed as part of a complete treatment plan for active tuberculosis. Its main uses include: 

  • Active Tuberculosis (TB): Rifacept 3 Tablet 10's is prescribed to treat the intensive phase of active tuberculosis. It combines multiple antibacterial agents to eradicate the infection from the lungs and other tissues, while reducing the risk of the bacteria developing resistance to the treatment.
  • Prevention of Treatment-Induced Nerve Pain: The medicine contains a specific protective vitamin component to prevent peripheral nerve damage, which is a common side effect associated with long-term tuberculosis therapy.

Key Benefits

Rifacept 3 Tablet 10's combines multiple anti-TB medicines with vitamin B6 in a single formulation, helping make long-term treatment more manageable. Its main benefits include:

  • Makes treatment easier to follow: Combines several prescribed ingredients in one tablet, reducing the need to take each medicine separately.
  • Supports consistent treatment: A simplified medicine schedule may make it easier to take treatment regularly and complete the prescribed course.
  • Promotes gradual recovery: As treatment controls the infection, symptoms such as cough, fever, night sweats, tiredness, and loss of appetite may gradually improve.
  • Helps restore strength and well-being: Effective treatment supports recovery from TB-related weakness and unintended weight loss, helping you gradually return to daily activities.
  • Protects against nerve problems: Pyridoxine (vitamin B6) helps reduce the risk of tingling, numbness, burning, or pain in the hands and feet associated with isoniazid treatment.

Directions for Use

  • Take Rifacept 3 Tablet 10's on an empty stomach, either 30 minutes before meals or 2 hours after meals, as directed by the doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.
  • Swallow Rifacept 3 Tablet 10's as a whole with a glass of water.
  • Do not chew, crush, or break it.

How Rifacept 3 Tablet 10's Works

Rifacept 3 Tablet 10's contains four active ingredients that work together to treat tuberculosis and help protect nerve health. Isoniazid blocks the production of mycolic acids, which are essential parts of the protective outer layer of TB bacteria. Without these substances, the bacteria cannot maintain their structure and survive. Pyrazinamide becomes active in the acidic environment found within infected cells. It helps kill slow-growing or less active TB bacteria that may be difficult for some other anti-TB medicines to reach. Pyridoxine (vitamin B6) helps prevent or reduce nerve problems associated with isoniazid, including tingling, numbness, burning, or pain in the hands and feet. Rifampicin blocks an enzyme called bacterial RNA polymerase. This prevents TB bacteria from using their genetic instructions to make proteins needed for growth and survival.
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Alcohol

Unsafe

You are recommended to avoid alcohol consumption while taking Rifacept 3 Tablet 10's. Alcohol intake, along with Rifacept 3 Tablet 10's, may cause increased liver damage. Please consult your doctor for more information.

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Pregnancy

Consult your doctor

Please consult your doctor if you are pregnant, planning for pregnancy or think you are pregnant; your doctor will prescribe Rifacept 3 Tablet 10's only if the benefits outweigh the risks.

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Breast Feeding

Unsafe

Rifacept 3 Tablet 10's is not recommended for use during breastfeeding since it is excreted into the breast milk and may harm a nursing baby. However, please consult your doctor before taking Rifacept 3 Tablet 10's if you are a breastfeeding mother.

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Driving

Unsafe

Rifacept 3 Tablet 10's may cause dizziness, vision problems, numbness and tingling sensation in hands and feet. Do not drive or operate machinery if you experience these symptoms.

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Liver

Caution

Please consult your doctor since Rifacept 3 Tablet 10's should be used with caution in patients with liver impairment/liver disease. Regular monitoring of liver function tests is also advised.

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Kidney

Caution

Please consult your doctor since Rifacept 3 Tablet 10's should be used with caution in patients with kidney impairment/kidney disease. Your doctor may adjust the dosage in case of renal dysfunction.

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Children

Caution

Rifacept 3 Tablet 10's is not recommended in children unless the doctor has prescribed it.

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Heart

Caution

Rifacept 3 Tablet 10's should be taken with caution in patients with heart problems. Therefore, please inform your doctor before using Rifacept 3 Tablet 10's.

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Geriatrics

Caution

Rifacept 3 Tablet 10's should be given with caution in elderly patients due to an increased risk of side effects. If you have any concerns about the usage of Rifacept 3 Tablet 10's in geriatrics, please consult your doctor.

What if I have taken an overdose of Rifacept 3 Tablet 10's

In case of an accidental overdose, seek immediate emergency medical attention. Symptoms of an overdose may include severe dizziness, vomiting, slurred speech, blurred vision, or loss of consciousness.

Diet & Lifestyle Advise

  • Strictly avoid alcohol: Drinking alcohol while taking this medicine significantly increases the risk of severe, life-threatening liver damage.
  • Avoid foods high in tyramine and histamine: Foods like aged cheese, red wine, cured meats, soy sauce, yeast extracts, and certain fish (such as tuna or mackerel) can interact with this medicine, causing sudden flushing, sweating, headaches, or a rapid heart rate.
  • Stay well-hydrated: Drink plenty of water throughout the day to help your kidneys efficiently process and flush out the medication's byproducts.
  • Maintain a nutrient-rich diet: Focus on eating balanced, high-protein meals to help your body rebuild strength and recover from the tuberculosis infection.
health query

Have a query?

How Soon It Starts Working

The time required for Rifacept 3 Tablet 10's to start to work: The time required for Rifacept 3 Tablet 10's to show its action is unknown. The time for which the effects of Rifacept 3 Tablet 10's last: The duration of action for Rifacept 3 Tablet 10's is clinically unknown.

What if you forget to take Rifacept 3 Tablet 10's

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and resume your regular timing. Do not take a double dose to make up for a missed one. Consistent daily dosing is critical for successful treatment.

Storage

• Store Rifacept 3 Tablet 10's tablets at room temperature, ideally between 15°C and 30°C (59°F to 86°F).

Drug Warnings

  • Expect orange-red body fluids: Rifampicin may turn urine, sweat, saliva, and tears orange-red. This effect is expected and usually harmless.
  • Avoid soft contact lenses: Orange-red tears may permanently stain soft contact lenses. Wear glasses during treatment if advised by your doctor.
  • Attend all monitoring appointments: Keep scheduled appointments for blood tests and other checks so your doctor can monitor your response and liver health.
  • Use additional contraceptive protection: Rifampicin may reduce the effectiveness of hormonal contraceptives, including birth-control pills, patches, implants, and some other hormonal methods. Ask your doctor about a suitable non-hormonal or additional method.
  • Do not stop treatment early: Continue taking the medicine for the full prescribed duration, even if you feel better. Missing doses or stopping early may cause the infection to return and increase the risk of drug-resistant TB.
  • Avoid alcohol: Alcohol can increase the risk of liver damage during treatment.
  • Report liver-related symptoms promptly: Contact your doctor if you develop yellowing of the skin or eyes, dark urine, persistent nausea or vomiting, severe abdominal pain, or unusual tiredness.

verifiedApollotooltip

The following medicines may interact with Rifacept 3 Tablet 10's and require closer monitoring or dose adjustments:

  • Hormonal Contraceptives: May significantly decrease the effectiveness of birth control pills, patches, vaginal rings, and implants, increasing the risk of unplanned pregnancy.
  • Anticonvulsants (Seizure Medicines): May increase the blood levels of medicines like phenytoin or carbamazepine, raising the risk of toxicity.
  • Blood Thinners: May reduce the effectiveness of oral anticoagulants like warfarin, requiring closer monitoring of blood clotting times.
  • Other Liver-Affecting Medications: Combining this with high doses of acetaminophen or other drugs known to affect the liver increases the risk of severe liver damage.

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verifiedApollotooltip

Certain foods or drinks may affect the safety or tolerability of Rifacept 3 Tablet 10's. Important interactions include:

  • Tyramine and Histamine-Rich Foods: Consuming aged cheeses, cured meats, yeast extracts, tuna, or mackerel can trigger flushing, rapid heart rate, sweating, and headaches due to altered chemical metabolism.

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Habit Forming

No

Therapeutic Class

[ANTI- TUBERCULOSIS]

FAQs

Rifacept 3 Tablet 10's is used to treat and prevent tuberculosis. It kills Mycobacterium tuberculosis which causes TB (tuberculosis).
Rifacept 3 Tablet 10's contains Isoniazid, Pyrazinamide, Pyridoxine (vitamin B6), and Rifampicin. Rifacept 3 Tablet 10's interferes with the growth and tuberculosis causing bacteria and kills it. Thus Rifacept 3 Tablet 10's effectively treats TB (tuberculosis).
Yes. Rifampicin in Rifacept 3 Tablet 10's can reduce the effectiveness of hormonal contraceptives, including birth control pills, patches, vaginal rings, and implants, increasing the risk of unintended pregnancy. Use a reliable non-hormonal method, such as condoms or a copper intrauterine device (IUD), during treatment. Consult your doctor to discuss the most suitable contraceptive option.
Rifacept 3 Tablet 10's may cause discolouration of teeth, sweat, urine, sputum (phlegm), saliva, or tears. The colour in tears may last for some time even after you stop taking Rifacept 3 Tablet 10's. Do not worry, as it is a common side-effect of Rifacept 3 Tablet 10's.
Rifacept 3 Tablet 10's can affect live vaccines like typhoid vaccine and decrease their effectiveness. Please consult a doctor before you start Rifacept 3 Tablet 10's if you are undergoing any vaccinations.
Yes. Rifacept 3 Tablet 10's can cause your tears to turn an orange-red colour due to rifampicin, which may permanently stain soft contact lenses. It is recommended to wear glasses instead of soft contact lenses during treatment. Consult your doctor or optometrist if you have any concerns.
Rifacept 3 Tablet 10's may cause liver problems, especially in people who are 35 and older. Consult your doctor if you notice symptoms, such as yellowing of eyes or skin, dark urine, pale stools, weakness, loss of appetite, nausea or vomiting. Your doctor may advise you to get regular liver tests while taking Rifacept 3 Tablet 10's to check how your liver functions.
This is a completely harmless and expected side effect caused by one of the active ingredients, rifampicin, which has a natural red pigment. It can colour your urine, sweat, saliva, and tears. Talk to your doctor if you experience any other unusual symptoms.
No, you must completely avoid alcohol during your treatment. Both this medication and alcohol are processed by the liver, and combining them significantly increases your risk of serious liver damage. Talk to your doctor if you need support with avoiding alcohol.
You should take this medicine on an empty stomach, either 1 hour before a meal or 2 hours after. Taking it with food reduces how much of the medicine your body absorbs, making it less effective. Talk to your doctor if you struggle with taking it on an empty stomach.
One of the anti-tuberculosis medicines in this tablet can cause nerve damage, leading to numbness, tingling, or burning in your hands and feet. Pyridoxine (vitamin B6) is included to protect your nervous system and prevent these side effects. Talk to your doctor if you still develop tingling sensations.
You must continue taking the medication for the exact duration prescribed, even if your symptoms disappear. Stopping early allows the surviving bacteria to multiply and become resistant to the drugs, making the infection much harder to treat. Talk to your doctor before making any changes.
Your doctor will order regular blood tests to monitor your liver function and blood counts, as some components of this medicine can affect your liver and blood cells. These tests help ensure the medication is safe for you to continue. Talk to your doctor if you have questions about your laboratory results.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

INDIA

Manufacturer/Marketer address

Concept Pharmaceuticals Ltd. 501 Jaisingh Business Center, 119, Sahar Road, Andheri (East) Mumbai - 400 099 India.
Other Info - RIF0266
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