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compositionComposition:QUININE-300MG
prescription
Prescription Medicine
info
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REZQ 300MG INJECTION 1ML is used to treat malaria. REZQ 300MG INJECTION 1ML contains Quinine, which treats malaria by increasing the levels of hemozoin (a toxic substance to the malarial parasite) in the blood. As a result, it kills the parasite and helps to stop the infection from spreading further. Common side effects of REZQ 300MG INJECTION 1ML are injection site reactions, nausea, restlessness, visual disturbances, vertigo (sudden internal or external spinning sensation), difficulty hearing or ringing in the ears, confusion and nervousness.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

QUININE-300MG

Manufacturer/Marketer :

Shreya Life Sciences Pvt Ltd

Consume Type :

Parenteral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About REZQ 300MG INJECTION 1ML

REZQ 300MG INJECTION 1ML is a prescription injection used to treat severe and life-threatening malaria infections. It is prescribed when the malaria parasite is resistant to other medications or when the patient is too ill to take pills by mouth. This critical medical treatment helps clear the infection from the bloodstream.

Since this medicine is given as an injection, a healthcare professional will inject it in a hospital or clinic. It is typically given at regular intervals to keep a steady amount of the medicine in your body. To support your recovery during treatment, it is important to rest completely and drink plenty of fluids to protect your kidneys.

While receiving this medicine, you may experience mild side effects like ringing in your ears or temporary headache. However, you must tell your healthcare team immediately if you notice severe side effects, such as a very fast or irregular heartbeat, severe dizziness, or sudden vision changes.

Before starting this treatment, tell your doctor if you have a history of heart, kidney, or liver disease. Do not take this medicine if you have had a severe allergic reaction to it in the past, or if you have a genetic condition called G6PD deficiency.

This medicine can interact with other drugs, including heart medications and blood thinners, which can increase your risk of severe side effects. You should also avoid alcohol during treatment as it can increase dizziness and liver strain. If you are pregnant, breastfeeding, or an older adult, consult your doctor to ensure this treatment is safe for you.

Uses of REZQ 300MG INJECTION 1ML

REZQ 300MG INJECTION 1ML is used in the treatment of malaria. The detailed uses of REZQ 300MG INJECTION 1ML are as follows:

  • Severe malaria: REZQ 300MG INJECTION 1ML helps by targeting and killing the malaria parasites inside your red blood cells, resolving life-threatening complications.
  • Malaria when oral medicines cannot be taken: REZQ 300MG INJECTION 1ML helps patients who are unable to swallow tablets due to severe vomiting, nausea, or unconsciousness caused by the infection.

Key Benefits

REZQ 300MG INJECTION 1ML helps treat severe malaria by killing the malaria parasites in your bloodstream. The following are the benefits of this medication:

  • Works rapidly when injected directly into the bloodstream to relieve malaria symptoms, such as high fever, severe chills, and intense body aches.
  • Provides an effective treatment for severe malaria, especially when oral treatment is not suitable or cannot be taken.
  • Ensures reliable absorption when administered by injection, making it effective even in patients with severe nausea or vomiting.

Directions for Use

  • Your doctor will determine the dosage and frequency depending on your condition.
  • REZQ 300MG INJECTION 1ML will be administered by a healthcare professional.
  • Do not self-administer.

How REZQ 300MG INJECTION 1ML Works

REZQ 300MG INJECTION 1ML works by attacking the malaria parasites that have invaded your red blood cells. Once injected, the medicine enters these cells and interferes with the parasite's internal survival process. Normally, the malaria parasite digests haemoglobin (the protein in your blood that carries oxygen) to grow. However, this digestion process produces a toxic substance that the parasite must neutralise to survive. This medicine blocks the parasite from neutralising this toxin. As the toxic buildup increases, it poisons and destroys the parasite, stopping the infection from spreading and allowing your body to recover.
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Alcohol

Caution

Avoid alcohol while using REZQ 300MG INJECTION 1ML since it can worsen the side effects.

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Pregnancy

Caution

REZQ 300MG INJECTION 1ML is not recommended for use in pregnancy unless clearly necessary. Hence, inform your doctor if you are pregnant or suspect pregnancy. Your doctor will weigh the benefits and potential risks before prescribing REZQ 300MG INJECTION 1ML.

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Breast Feeding

Caution

REZQ 300MG INJECTION 1ML is not recommended for use while breastfeeding unless clearly necessary. So, inform your doctor if you are a breastfeeding mother. Your doctor will weigh the benefits and potential risks before prescribing REZQ 300MG INJECTION 1ML.

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Driving

Caution

REZQ 300MG INJECTION 1ML may affect your ability to drive or operate machinery. Hence, avoid driving or using machinery until you are alert.

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Liver

Caution

Let your doctor know if you have any history of liver diseases before using the REZQ 300MG INJECTION 1ML. Your doctor may suggest tests for monitoring your liver function while on treatment with REZQ 300MG INJECTION 1ML.

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Kidney

Caution

Let your doctor know if you have any history of kidney diseases before using the REZQ 300MG INJECTION 1ML. Your doctor may suggest tests for monitoring your liver function while on treatment with REZQ 300MG INJECTION 1ML. Dose adjustments may be necessary based on your condition.

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Children

Safe if prescribed

Your doctor will weigh the benefits and potential risks before prescribing REZQ 300MG INJECTION 1ML. The dose of this medicine will be decided by your doctor based on the age and condition of your child.

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Heart

Caution

REZQ 300MG INJECTION 1ML can affect heart rhythm and worsen existing cardiac conditions, so it's risky for heart patients. Always consult your doctor before use to avoid serious complications.

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Geriatrics

Caution

Geriatric patients should receive REZQ 300MG INJECTION 1ML only under strict medical supervision. Older adults are more susceptible to side effects like heart rhythm disturbances and low blood sugar, so careful evaluation is essential before use.

What if I have taken an overdose of REZQ 300MG INJECTION 1ML

Since this medicine is injected under strict medical supervision, an overdose is rare. However, if you receive too much of this medicine, it can lead to serious heart rhythm issues, severe vision changes, or low blood pressure. If you suspect an overdose or experience sudden, severe symptoms, seek immediate emergency medical help.

Diet & Lifestyle Advise

  • Drink plenty of fluids: Staying well-hydrated with water, broths, or oral rehydration solutions helps your body flush out toxins and supports your kidneys during malaria recovery.
  • Keep a source of sugar nearby: This medicine can cause your blood sugar to drop. Keep fruit juice or sugary snacks close by, especially if you feel shaky, sweaty, or unusually weak.
  • Prioritise complete bed rest: Rest is vital to help your immune system fight the infection and to prevent dizziness or falls during treatment.
  • Eat gentle, simple foods: When you are able to eat, choose bland foods like rice, toast, or crackers to help settle your stomach.
     
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How Soon It Starts Working

The time required for REZQ 300MG INJECTION 1ML to start to work: The time required for REZQ 300MG INJECTION 1ML to show its action is unknown. The time for which the effects of REZQ 300MG INJECTION 1ML last: The duration of action for REZQ 300MG INJECTION 1ML is unknown.

What if you forget to take REZQ 300MG INJECTION 1ML

Because this medicine is injected by a healthcare professional in a hospital or clinic, it is highly unlikely that you will miss a dose. If you think a scheduled injection was missed, notify your healthcare provider immediately.

Storage

• The vials should be kept at room temperature, between 20°C and 25°C (68°F to 77°F).

Drug Warnings

  • Inspect the vial: Ensure the injection fluid is clear and free of any visible particles before it is injected.
  • Monitor your heart: Request or ensure that your medical team monitors your heart rhythm (ECG) during the infusion, as this medicine can affect your heart's electrical activity.
  • Check blood sugar levels regularly: Ensure your blood sugar is monitored closely, especially if you are pregnant, as this treatment can cause sudden, severe drops in blood sugar.
  • Rise slowly from lying or sitting: To prevent falls from sudden dizziness, take your time when standing up during or after your treatment.
  • Report hearing changes immediately: Tell your healthcare team right away if you experience sudden ringing in your ears, muffled hearing, or vision changes.
     

Drug-Drug Interactions

verifiedApollotooltip
  • Heart rhythm medications (e.g., amiodarone, quinidine): Combining this medicine with drugs that affect your heart's electrical rhythm can increase the risk of serious, irregular heartbeats.
  • Blood thinners (e.g., warfarin): It may increase the effects of blood-thinning medicines, which can raise your risk of bleeding or bruising.
  • Stomach acid reducers (e.g., magnesium hydroxide, aluminium hydroxide): Some antacids can interfere with how your body absorbs or processes this medicine.
     
QuinineZiprasidone
Critical
QuininePazopanib
Severe

Drug-Drug Interactions

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QuinineZiprasidone
Critical
How does the drug interact with Rezq 300mg Injection 1ml:
Co-administration of Rezq 300mg Injection 1ml with Ziprasidone can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Rezq 300mg Injection 1ml with Ziprasidone together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any symptoms such as sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not discontinue any medications without consulting a doctor.
QuininePazopanib
Severe
How does the drug interact with Rezq 300mg Injection 1ml:
Taking Pazopanib with Rezq 300mg Injection 1ml may significantly reduces the blood levels of pazopanib.

How to manage the interaction:
Although there is a interaction between Pazopanib and Rezq 300mg Injection 1ml, but it can be taken if your doctor has advised it. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, fast or pounding heartbeats, chest pain or tightness, pain in your arms, back, neck, or jaw, shortness of breath, numbness or weakness on one side of your body, and difficulty speaking. Do not stop using any medications without a doctor's advice.
QuinineLidocaine
Severe
How does the drug interact with Rezq 300mg Injection 1ml:
Taking Lidocaine with Rezq 300mg Injection 1ml may cause methemoglobinemia (blood disorder in which too little oxygen is delivered to your cells).

How to manage the interaction:
Although taking Lidocaine and Rezq 300mg Injection 1ml together can evidently cause an interaction, it can be taken if your doctor has suggested it. However, consult the doctor immediately if you develop gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion. Do not stop using any medications without consulting doctor.
QuinineGatifloxacin
Severe
How does the drug interact with Rezq 300mg Injection 1ml:
Taking Gatifloxacin with Rezq 300mg Injection 1ml can increase the risk or severity of irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Gatifloxacin with Rezq 300mg Injection 1ml together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
QuinineMoxifloxacin
Severe
How does the drug interact with Rezq 300mg Injection 1ml:
Using moxifloxacin together with Rezq 300mg Injection 1ml can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Moxifloxacin with Rezq 300mg Injection 1ml together can possibly result in an interaction, but it can be taken if your doctor has advised it. If you experience any symptoms like an irregular heartbeat, heart problems, or feeling dizzy or short of breath, call your doctor right away. Do not discontinue any medications without first consulting your doctor.
QuinineAlfuzosin
Severe
How does the drug interact with Rezq 300mg Injection 1ml:
Taking Alfuzosin and Rezq 300mg Injection 1ml can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Alfuzosin and Rezq 300mg Injection 1ml together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
QuinineErythromycin
Severe
How does the drug interact with Rezq 300mg Injection 1ml:
Coadministration of Rezq 300mg Injection 1ml and erythromycin may significantly increase the blood levels and effects of Rezq 300mg Injection 1ml

How to manage the interaction:
Although taking erythromycin and Rezq 300mg Injection 1ml together can possibly result in an interaction, they can be taken together if prescribed by a doctor. However, if you experience headache, flushing, sweating, nausea, vomiting, diarrhoea, stomach pain, dizziness, ringing in the ears, hearing loss, blurred vision, vision loss, and abnormal heart rhythm, contact your doctor immediately. Do not stop using any medications without consulting a doctor.
QuinineVigabatrin
Severe
How does the drug interact with Rezq 300mg Injection 1ml:
Co-administration of Vigabatrin with Rezq 300mg Injection 1ml may increase the risk of serious side effects associated with vision loss, especially if used together for prolonged periods.

How to manage the interaction:
There may be a possibility of interaction between Vigabatrin and Rezq 300mg Injection 1ml, but it can be taken if prescribed by a doctor. Routine vision testing is advised during treatment with vigabatrin. Do not discontinue any medications without a doctor's advice.
QuinineCeritinib
Severe
How does the drug interact with Rezq 300mg Injection 1ml:
Taking Ceritinib with Rezq 300mg Injection 1ml may increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking Ceritinib and Rezq 300mg Injection 1ml together can evidently cause an interaction, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
QuinineEfavirenz
Severe
How does the drug interact with Rezq 300mg Injection 1ml:
Taking Efavirenz and Rezq 300mg Injection 1ml can increase the risk or severity of irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Efavirenz and Rezq 300mg Injection 1ml together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip
  • Alcohol: Avoid alcohol during treatment, as it can worsen dizziness and drowsiness, and increase the risk of liver strain.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTI- MALARIALS]

FAQs

REZQ 300MG INJECTION 1ML is used to treat Malaria.
REZQ 300MG INJECTION 1ML belongs to the class of anti-malarial drugs, containing Quinine that treats malaria by increasing the levels of hemozoin (a toxic substance to the malarial parasite) in the blood. As a result, it kills the parasite and helps to stop the infection from spreading further.
You should not take REZQ 300MG INJECTION 1ML if you have or ever had a heart rhythm disorder called Long QT syndrome, glucose-6-phosphate dehydrogenase deficiency (G-6-PD), myasthenia gravis (a muscle disorder), optic neuritis (inflammation of the nerves in your eyes) if taking REZQ 300MG INJECTION 1ML in the past ever caused bleeding.
REZQ 300MG INJECTION 1ML can cause a lowering of blood sugar levels. So, if you are diabetic, please inform your doctor before starting treatment with REZQ 300MG INJECTION 1ML, and dose adjustment might be required depending upon your medical condition.
REZQ 300MG INJECTION 1ML may affect the heart rhythm and cause QT prolongation (heart muscle takes longer than usual to recharge between beats). This QT prolongation can cause a serious fast/irregular heartbeat. Hence it is advised to inform your doctor if you have any heart-related problems like heart failure, slow heartbeat, QT prolongation in EKG or ECG (electrocardiogram) and a family history of heart diseases.
Glucose-6-phosphate dehydrogenase deficiency is a hereditary condition that affects red blood cells. A defect in an enzyme called glucose-6-phosphate dehydrogenase in affected individuals causes red blood cells to break down prematurely. It leads to hemolytic anaemia, which happens when red blood cells are destroyed faster than the body can replenish them.
REZQ 300MG INJECTION 1ML is injected slowly into a vein as an intravenous (IV) infusion or given as a deep injection into a large muscle. This must only be done by a healthcare professional in a medical setting. Talk to your doctor if you have questions about how it will be given.
The injection is used for severe malaria or when a patient is too sick, vomiting, or unable to swallow pills. Once you are feeling better and can tolerate oral medications, your doctor may switch you to tablets. Talk to your doctor for more details.
Yes, ringing in the ears (tinnitus) is a known side effect of this medicine. It is usually temporary and improves once the treatment is completed. If it becomes severe, talk to your doctor or pharmacist.
Severe malaria is highly dangerous for both mother and baby, so REZQ 300MG INJECTION 1ML is often used if it is the most effective option. Your doctor will weigh the benefits against the risks. Talk to your doctor to understand your options.
No, you should avoid alcohol. Alcohol can worsen side effects like dizziness and put extra strain on your liver while you are recovering from a severe infection. Talk to your doctor or pharmacist.
Dizziness is a common side effect. Sit or lie down immediately to avoid falling, and inform your nurse or doctor right away so they can check your blood pressure and blood sugar. Talk to your doctor if this feeling persists.

Disclaimer

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Country of origin

India

Manufacturer/Marketer address

SHREYA HOUSE, 301/A, Pereira Hill Road, Andheri East, Mumbai - 400 099, India
Other Info - REZ0005
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