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compositionComposition:SEVELAMER-800MG
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Renvela 800 mg Sachet is used to control high phosphate levels in the body (hyperphosphataemia) in adult patients on dialysis (a blood clearance technique), patients undergoing hemodialysis (using a blood filtration machine), and patients with chronic kidney disease. It is also used for the treatment of bone disease. It contains Sevelamer, which effectively reduces excess phosphate levels in the blood, prevents the unsafe build-up of phosphate in your body and helps keep your bones strong. It may cause common side effects such as vomiting, upper abdominal pain, nausea, constipation, and diarrhoea. Let the doctor know if you are pregnant, breastfeeding, taking other medicines or have pre-existing medical conditions.

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Reviewed By Santoshini Reddy G , M Pharmacy
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More about the Product

Composition :

SEVELAMER-800MG

Manufacturer/Marketer :

Sanofi India Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Renvela 800 mg Sachet

Renvela 800 mg Sachet is an oral powder medication used to control high levels of phosphorus in the blood. This medicine is specifically prescribed for adults with chronic kidney disease who are undergoing dialysis. By keeping your blood phosphorus levels in a safe range, it helps protect your bones and cardiovascular system from harmful mineral buildup.

For this medicine to work effectively, you must take it consistently with every meal and snack as prescribed by your doctor. It is taken orally and must always be mixed with water and consumed during your meals. To get the best results from your treatment, your doctor will also advise you to follow a low-phosphorus diet and make healthy lifestyle choices.

While taking this medication, you may experience mild digestive symptoms like nausea, bloating, or mild constipation. If you experience severe stomach pain, unusual vomiting, or severe constipation, you should contact your doctor immediately.

Do not take this if you have a bowel blockage or a history of severe bowel obstruction. Before starting, tell your doctor if you have swallowing difficulties, severe constipation, or have recently had major stomach or bowel surgery.

This medicine can interact with other oral drugs by stopping them from being properly absorbed, so you may need to take your other pills at different times of the day. If you are pregnant, breastfeeding, or planning a pregnancy, consult your doctor or pharmacist before using this medicine.

Uses of Renvela 800 mg Sachet

Renvela 800 mg Sachet is used to control high phosphate levels in patients with kidney problems. The detailed uses of Renvela 800 mg Sachet are as follows:

  • High blood phosphorus levels (hyperphosphatemia): In patients with chronic kidney disease who are on dialysis, Renvela 800 mg Sachet binds to the phosphorus in food within the digestive tract, preventing it from entering the bloodstream and causing mineral imbalances.

Key Benefits

  • Protects bone health: Keeping phosphorus levels low prevents the body from pulling calcium out of your bones, helping to keep your bones strong and reducing the risk of bone pain or fractures.
  • Reduces harmful calcium buildup: High phosphorus can combine with calcium to form hard deposits in your heart, blood vessels, and lungs. This medicine lowers that risk, protecting your cardiovascular system.
  • Integrates smoothly with meals: The oral powder formulation can be easily mixed with water, making it a convenient option to take alongside your daily meals and snacks.
Side effects of Renvela 800 mg Sachet
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Here are the few steps for dealing with itching caused by drug use:
  • Report the itching to your doctor immediately; they may need to change your medication or dosage.
  • Use a cool, damp cloth on the itchy area to help soothe and calm the skin, reducing itching and inflammation.
  • Keep your skin hydrated and healthy with gentle, fragrance-free moisturizers.
  • Try not to scratch, as this can worsen the itching and irritate your skin.
  • If your doctor prescribes, you can take oral medications or apply topical creams or ointments to help relieve itching.
  • Track your itching symptoms and follow your doctor's guidance to adjust your treatment plan if needed. If the itching persists, consult your doctor for further advice.
Here are the steps to manage Joint Pain caused by medication usage:
  • Please inform your doctor about joint pain symptoms, as they may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Your doctor may prescribe common pain relievers if necessary to treat joint discomfort.
  • Maintaining a healthy lifestyle is key to relieving joint discomfort. Regular exercise, such as low-impact sports like walking, cycling, or swimming, should be combined with a well-balanced diet. Aim for 7-8 hours of sleep per night to assist your body in repairing and rebuilding tissue.
  • Applying heat or cold packs to the affected joint can help reduce pain and inflammation.
  • Please track when joint pain occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
  • If your joint pain is severe or prolonged, consult a doctor to rule out any underlying disorders that may require treatment.
Managing Medication-Triggered Bronchitis (Inflammation of the bronchial tubes): A Step-by-Step Guide:
  • If you experience symptoms like coughing, wheezing, chest tightness, or difficulty breathing after taking medication, seek medical attention immediately.
  • Your healthcare provider will work with you to stop the medication causing the reaction, start alternative treatments, and provide supportive therapy.
  • To manage symptoms and prevent complications, follow your doctor's advice to use inhalers or nebulizers as prescribed, practice good hygiene, avoid irritants, stay hydrated, and get plenty of rest.
  • Regularly track your symptoms and report any changes or concerns to your healthcare provider.
Here are the seven steps to manage medication-triggered Dyspnea (Difficulty Breathing or Shortness of Breath):
  • Tell your doctor immediately if you experience shortness of breath after taking medication.
  • Your doctor may adjust the medication regimen or dosage or give alternative medical procedures to minimize the symptoms of shortness of breath.
  • Monitor your oxygen levels and breathing rate regularly to track changes and potential side effects.
  • For controlling stress and anxiety, try relaxation techniques like deep breathing exercises, meditation, or yoga.
  • Make lifestyle changes, such as quitting smoking, exercising regularly, and maintaining a healthy weight.
  • Seek emergency medical attention if you experience severe shortness of breath, chest pain, or difficulty speaking.
  • Follow up regularly with your doctor to monitor progress, adjust treatment plans, and address any concerns or questions.

Directions for Use

  • Take Renvela 800 mg Sachet with food or as advised by your doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication.
  • Check the label for directions and use as advised. Mix the recommended amount of powder using the dosing spoon in 30 mL of water, stir well, and drink it within 30 minutes.
  • Do not store the dissolved mixture for later use. Avoid mixing the contents with very hot or cold liquids.

How Renvela 800 mg Sachet Works

Renvela 800 mg Sachet works directly inside your digestive system, acting like a chemical sponge. When you eat, your food contains phosphorus, which normally gets absorbed through your stomach and intestines into your bloodstream. When you take this medicine with a meal, it mixes with the food in your digestive tract. Instead of letting the phosphorus pass into your blood, the medicine binds tightly to the phosphorus molecules. Because the medicine itself cannot be absorbed by your body, it stays in your digestive tract and is safely eliminated through your normal bowel movements, carrying the bound phosphorus out with it.
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Alcohol

Consult your doctor

It is not known if alcohol interacts with Renvela 800 mg Sachet. Please consult a doctor.

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Pregnancy

Caution

Sevelamer is a Category C pregnancy medicine. Please consult your doctor if you have any concerns; your doctor will prescribe you Renvela 800 mg Sachet only if the benefits outweigh the risks.

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Breast Feeding

Caution

It is unknown if Sevelamer passes into breastmilk or affects the baby. Please consult your doctor before using Renvela 800 mg Sachet if you are a breastfeeding mother.

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Driving

Safe if prescribed

Renvela 800 mg Sachet has no or negligible influence on the ability to drive or operate any machinery.

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Liver

Caution

Renvela 800 mg Sachet should be used with caution in patients with liver impairment/liver disease. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Safe if prescribed

Renvela 800 mg Sachet may be safe for patients with kidney problems. However, please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Caution

Renvela 800 mg Sachet is not recommended for children below 6 years as its safety and effectiveness are not known.

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Heart

Consult your doctor

Inform your doctor if you have heart disease before using Renvela 800 mg Sachet. Your doctor will prescribe only if the benefits outweigh the risks.

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Geriatrics

Caution

Renvela 800 mg Sachet may require dose adjustment in elderly patients based on their condition and medical requirements.

What if I have taken an overdose of Renvela 800 mg Sachet

If you suspect an overdose, or if someone has accidentally swallowed too much of this medicine, seek immediate medical attention or contact a poison control center right away. While a single overdose is unlikely to be life-threatening, it can lead to severe constipation or other bowel issues.

Diet & Lifestyle Advise

  • Follow a low-phosphorus diet: Work closely with a renal dietitian to limit foods high in phosphorus, such as cheese, milk, nuts, seeds, beans, and chocolate.
  • Avoid processed foods and sodas: Read ingredients carefully and stay away from items containing inorganic phosphate additives (look for words with 'phos' on the label) and dark colas, as these are highly absorbed by the body.
  • Stay safely hydrated: Drink the amount of fluids recommended by your nephrology team to help keep your stools soft and prevent constipation.
  • Keep a food journal: Tracking what you eat can help you identify hidden sources of phosphorus and make it easier to manage your levels.
  • Attend regular blood tests: Always go to your scheduled lab appointments so your healthcare team can track your phosphorus and calcium levels and adjust your treatment plan.
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How Soon It Starts Working

The time required for Renvela 800 mg Sachet to start to work: The time required for Renvela 800 mg Sachet to show its action is not clinically established. The time for which the effects of Renvela 800 mg Sachet last: The duration of action for Renvela 800 mg Sachet is not clinically established.

What if you forget to take Renvela 800 mg Sachet

If you miss a dose, take it with your next meal or snack if it is within a short time of your regular meal. If a long time has passed, skip the missed dose and take your next regular dose with your next meal. Do not take a double dose to make up for a forgotten one, and never take this medicine on an empty stomach.

Storage

• Store Renvela 800 mg Sachet powder packets at room temperature, strictly between 15°C and 30°C (59°F to 86°F).

Drug Warnings

  • Always mix the powder with the recommended amount of water; never attempt to swallow the powder dry, as this can cause a choking hazard or irritate your esophagus.
  • Be sure to drink the mixture within 30 minutes of stirring; if it sits, the powder will settle to the bottom, so stir it again quickly before drinking.
  • Always take this medication with your meals or snacks, as it cannot bind phosphorus if there is no food in your stomach.
  • Monitor your bowel movements closely and let your doctor know immediately if you develop severe constipation or have trouble passing stools.
  • If you take other oral medications, check with your pharmacist to make sure they are spaced out properly so this medicine does not interfere with their absorption.

Drug-Drug Interactions

verifiedApollotooltip
  • Certain antibiotics (such as ciprofloxacin): Taking these at the same time as Renvela 800 mg Sachet can significantly lower their absorption. Take your antibiotic either 1 hour before or 3 hours after taking your phosphate binder.
  • Thyroid medications (such as levothyroxine): This medicine may reduce the absorption of your thyroid hormones. Your doctor may need to monitor your thyroid levels more closely.
  • Immunosuppressants (such as mycophenolate mofetil): The absorption of these medications can be reduced, potentially decreasing their ability to prevent organ transplant rejection. Consult your doctor about proper dosing separation.
SevelamerEnoxacin
Severe

Drug-Drug Interactions

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SevelamerEnoxacin
Severe
How does the drug interact with Renvela 800 mg Sachet:
Co-administration of Enoxacin and Renvela 800 mg Sachet can decrease the blood levels and effectiveness of Enoxacin.

How to manage the interaction:
Co-administration of Enoxacin and Renvela 800 mg Sachet can lead to an interaction, but it can be taken if advised by your doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Renvela 800 mg Sachet:
Gemifloxacin's efficiency can be decreased by Renvela 800 mg Sachet if it prevents the drug from being absorbed into the bloodstream. this is caused by the combined use of gemifloxacin and Renvela 800 mg Sachet.

How to manage the interaction:
Co-administration of enoxacin and Renvela 800 mg Sachet can lead to an interaction, but it can be taken if your doctor advises. It has been advised to separate the dosing of these medications by at least 4 hours and consult the doctor if your symptoms do not improve. Do not stop using any medications without a doctor's advice.
SevelamerErgocalciferol
Severe
How does the drug interact with Renvela 800 mg Sachet:
Co-administration of Renvela 800 mg Sachet with Ergocalciferol can decrease the effects of Ergocalciferol.

How to manage the interaction:
Co-administration of Renvela 800 mg Sachet with Ergocalciferol can lead to an interaction, but they can be taken if advised by your doctor. Consult the doctor if your symptoms worsen. Do not stop using any drugs without a doctor's advice.

Drug-Food Interactions

verifiedApollotooltip
  • No clinically significant food interactions are known with Renvela 800 mg Sachet when used as directed.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[HYPOPHOSPHATEMIC AGENT]

FAQs

Renvela 800 mg Sachet is used to control high phosphate levels in the body (hyperphosphataemia)‚ in adult patients on dialysis (a blood clearance technique), patients undergoing hemodialysis (using a blood filtration machine), and patients with chronic kidney disease. It is also used for the treatment of bone disease.
Renvela 800 mg Sachet contains sevelamer, which binds to phosphate in the gut and reduces its absorption. This helps lower high phosphate levels in the blood and prevents their harmful build-up in the body.
No, do not stop taking Renvela 800 mg Sachet on your own. Taking Renvela 800 mg Sachet is important to maintain phosphate levels and prevent calcification in the blood vessels. Consult your doctor if you consider stopping Renvela 800 mg Sachet treatment.
The side effects of Renvela 800 mg Sachet include diarrhoea, headache, stomach upset, and constipation. If these side effects persist or worsen, please consult your doctor.
Take Renvela 800 mg Sachet for as long as it is prescribed by your doctor. The dose and duration will depend on the response to treatment. Follow your doctor's instructions and do not stop taking Renvela 800 mg Sachet on your own.
Yes, Renvela 800 mg Sachet can be taken with food as it works by binding to phosphate from food.
Renvela 800 mg Sachet should be avoided by patients who are allergic to it and who have low phosphate levels in blood. Additionally, patients having intestinal obstruction should also avoid taking Renvela 800 mg Sachet.
You are recommended to consult your doctor before taking other medicines with Renvela 800 mg Sachet to avoid drug interactions.
No, you should not take this medicine on an empty stomach. It works by binding to phosphorus in your food, so it must be taken during meals or snacks to be effective. Talk to your doctor if you have questions about your eating schedule.
Water is the most common and recommended liquid for mixing this powder. Do not mix it with hot liquids or carbonated beverages. Talk to your doctor or pharmacist for specific liquid recommendations.
You should drink the prepared mixture within 30 minutes of mixing it. If the powder has settled to the bottom before you finish, stir it again vigorously before drinking. Talk to your doctor if you have trouble swallowing the mixture.
This medicine is not absorbed into your bloodstream, which reduces risk, but you should still exercise caution. If you are pregnant, planning to become pregnant, or breastfeeding, talk to your doctor to weigh the benefits and risks before starting this medication.
The medication is designed to bind phosphorus, but it cannot bind all of it if your dietary intake is excessively high. Combining the medicine with a low-phosphorus diet is the most effective way to keep your blood phosphorus levels in a safe range. Talk to your doctor or a renal dietitian for personalized dietary advice.
Yes, constipation is a common side effect of Renvela 800 mg Sachet. If you become constipated, talk to your doctor, who may recommend dietary or fluid changes or a suitable stool softener. Seek medical attention if constipation is severe or accompanied by severe abdominal pain, as these may indicate an intestinal blockage.
Your doctor will regularly monitor your blood tests while you are taking Renvela 800 mg Sachet. These may include serum phosphate, calcium, bicarbonate and chloride levels, and may also include vitamin D, A, E, K and folic acid levels when appropriate. The frequency of testing depends on your condition, treatment response and your doctor's advice.

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Country of origin

India

Manufacturer/Marketer address

CT Survey No.117-B, L&T Business Park, Saki Vihar Road, Powai, Mumbai 400072.
Other Info - REN0172
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