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Reluease Tablet 10's is a combination medication used to manage symptoms of uterine fibroids. It helps reduce heavy menstrual bleeding, relieve pelvic pain, decrease fibroid size, and improve overall quality of life in affected women.

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Written By Dr. Lakshmithulasi Yarragunta , PharmD (PB)
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Manufacturer/Marketer :

Sun Pharmaceutical Industries Ltd

Consume Type :

Oral

Expires on or after :

Jan-28

Return Policy :

Not Returnable

About Reluease Tablet 10's

Reluease Tablet 10's is a prescription oral medicine used to manage heavy menstrual bleeding associated with uterine fibroids and to treat moderate to severe pain associated with endometriosis in premenopausal women. It helps control hormone levels to reduce these painful and disruptive symptoms, allowing you to return to your normal daily activities. This treatment is typically prescribed for premenopausal women and is not intended for use after menopause.

For the best results, you must take Reluease Tablet 10's consistently once every day at the same time. You can take Reluease Tablet 10's with or without food. To support your treatment, incorporating certain lifestyle adjustments, such as maintaining a balanced diet rich in calcium and vitamin D and performing regular weight-bearing exercises, can help support your bone health during therapy.

While taking Reluease Tablet 10's, some people may experience mild side effects like hot flashes, night sweats, headache, or irregular vaginal bleeding. While these are common as your body adjusts, you should contact your doctor immediately if you experience severe symptoms such as sudden leg pain, shortness of breath, or yellowing of your skin or eyes.

Do not take this if you have a history of blood clots, severe high blood pressure, heart disease, osteoporosis, or liver damage. It is also important to tell your doctor if you have a history of depression or kidney problems before starting Reluease Tablet 10's. Reluease Tablet 10's should not be taken by anyone who is pregnant or trying to become pregnant.

Reluease Tablet 10's can interact with other substances, including certain seizure medications, tuberculosis treatments, and herbal supplements like St. John's Wort, which can make the treatment less effective. Smoking while taking Reluease Tablet 10's significantly increases your risk of serious cardiovascular side effects, including blood clots, stroke, and heart attacks. Always consult your doctor if you are breastfeeding or if you have questions about how your other medications might interact with this treatment.

Uses of Reluease Tablet 10's

Reluease Tablet 10's is used in the treatment of heavy menstrual bleeding associated with uterine fibroids and endometriosis-associated pain. The detailed uses of Reluease Tablet 10's are as follows:

  • Heavy menstrual bleeding from uterine fibroids: Reluease Tablet 10's helps significantly reduce excessive blood loss during your period by regulating the hormones that stimulate fibroid growth and bleeding.
  • Endometriosis-associated pain: Reluease Tablet 10's helps relieve moderate to severe pelvic pain, painful periods, and pain during intercourse by reducing the estrogen levels that cause endometrial tissue to grow outside the uterus.

Key Benefits

Reluease Tablet 10's helps manage heavy menstrual bleeding and endometriosis-related pain by regulating hormone activity. It can reduce excessive bleeding and pelvic pain, helping improve daily comfort and quality of life.

Benefits may include:

  •  Helps reduce heavy menstrual bleeding associated with uterine fibroids and lowers the risk of blood loss related anemia.
  • Helps relieve endometriosis-associated pelvic pain, menstrual cramps, and pain during intercourse.
  • May reduce the frequency and severity of painful periods.
  • Helps improve daily activities, sleep, and overall comfort by controlling troublesome symptoms.
  • Combines three active ingredients in a single daily tablet, making treatment more convenient.
  • Supports long-term symptom management when taken regularly as prescribed by a healthcare professional.

Directions for Use

  • Reluease Tablet 10's can be taken with or without food as advised by the doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safe and effective use.
  • It is advised to take Reluease Tablet 10's within the first 7 days of start of the menstrual bleeding.
  • Swallow Reluease Tablet 10's as a whole with a glass of water.
  • Do not break, crush or chew it

How Reluease Tablet 10's Works

Reluease Tablet 10's contains Relugolix, Estradiol, and Norethindrone Acetate. Relugolix: It is a gonadotropin releasing hormone (GnRH) receptor antagonist that blocks signals responsible for stimulating the ovaries to produce estrogen and progesterone. Lowering these hormone levels helps reduce heavy menstrual bleeding and pain associated with uterine fibroids and endometriosis. Estradiol: It is a form of estrogen given in a low dose as part of an add back approach. It helps reduce the effects of low estrogen levels, such as hot flashes, and helps limit bone loss during treatment. Norethindrone Acetate: It is a progestin that helps protect the lining of the uterus from excessive thickening caused by estrogen. This provides important protection for the uterine lining while estradiol is used.
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Alcohol

Unsafe

You are recommended to avoid alcohol consumption while taking Reluease Tablet 10's to avoid unpleasant side effects. Alcohol intake, along with Reluease Tablet 10's, may cause increased drowsiness.

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Pregnancy

Unsafe

Reluease Tablet 10's is contraindicated for use in pregnant women. Therefore, let your doctor know if you are pregnant or planning for pregnant before taking Reluease Tablet 10's.

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Breast Feeding

Unsafe

Reluease Tablet 10's should not be taken during breastfeeding as it passes into the breastmilk and may harm the nursing baby. Please consult your doctor.

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Driving

Safe if prescribed

Reluease Tablet 10's is unlikely to affect your ability to drive. However, drive or operate heavy machinery only if you are alert.

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Liver

Consult your doctor

If you have a history of liver disease, inform the doctor before taking Reluease Tablet 10's. Reluease Tablet 10's is not recommended for use in patients with severe liver impairment.

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Kidney

Consult your doctor

If you have a history of liver disease, inform the doctor before taking Reluease Tablet 10's.

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Children

Unsafe

Reluease Tablet 10's is not recommended for use in children below 12 years of age.

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Heart

Consult your doctor

Please inform your doctor about any existing heart problems before receiving Reluease Tablet 10's.

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Geriatrics

Consult your doctor

Reluease Tablet 10's is not recommended for use in elderly patients, unless prescribed by the doctor.

What if I have taken an overdose of Reluease Tablet 10's

In case of an accidental overdose, seek immediate medical attention or contact your local poison control center right away, even if you do not feel any symptoms.

Diet & Lifestyle Advise

  • Support bone health: Because hormone therapies can impact bone mineral density, ensure you consume foods rich in calcium and vitamin D, such as dairy products, leafy green vegetables, and fortified foods. Talk to your doctor about whether calcium supplements are right for you.
  • Avoid smoking: Smoking significantly increases your risk of serious cardiovascular complications, such as stroke, heart attack, and blood clots, while taking hormone-containing medications.
  • Manage hot flashes: Limit your intake of caffeine, alcohol, and very spicy foods, as these are common triggers that can worsen hot flashes and night sweats.
  • Keep a symptom diary: Track your bleeding patterns and pain levels daily. Sharing this log with your doctor helps them monitor how well the treatment is working for you.
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How Soon It Starts Working

The time required for Reluease Tablet 10's to start to work: The time required for Reluease Tablet 10's to start to work is unknown.
The time for which the effects of Reluease Tablet 10's last: The effect of Reluease Tablet 10's that lasts is unknown.

What if you forget to take Reluease Tablet 10's

If you miss a dose, take it as soon as you remember on the same day, and then return to your normal daily schedule. If you do not remember until the next day, skip the missed dose entirely and take your regular dose at your scheduled time. Do not take two doses at the same time to make up for a missed tablet.

Storage

•Store Reluease Tablet 10's at room temperature, strictly between 68°F and 77°F (20°C to 25°C).

Drug Warnings

  • Use reliable contraception: Use a reliable non-hormonal method of birth control, such as condoms or a diaphragm, during treatment and for at least 1 week after stopping Reluease Tablet 10's, as it may harm an unborn baby.
  • Avoid hormonal contraceptives: Do not use hormonal contraceptives, such as birth control pills, patches, or hormonal implants, while taking Reluease Tablet 10's unless specifically advised by your doctor, as they may affect how Reluease Tablet 10's works or increase the risk of side effects.
  • Monitor menstrual bleeding: Your periods may become lighter or stop completely during treatment. Tell your doctor if you continue to have heavy, prolonged, or unpredictable bleeding.
  • Monitor bone health: Long-term treatment may reduce bone mineral density. Your doctor may recommend regular bone density scans (DXA scans), particularly if treatment continues for an extended period. Treatment is generally limited to 24 months because of the risk of bone loss.
  • Check your blood pressure regularly: Have your blood pressure monitored during treatment, as Reluease Tablet 10's may cause blood pressure to increase in some people.

verifiedApollotooltip
  • Antifungal medicines (e.g., ketoconazole, itraconazole): These medicines may increase the amount of Reluease Tablet 10's in your body and raise the risk of side effects.
  • Anti-seizure medicines (e.g., carbamazepine): These medicines may lower the amount of Reluease Tablet 10's in your body and reduce its effectiveness.
  • Antibiotics (e.g., erythromycin): These medicines may increase the amount of Reluease Tablet 10's in your body and increase the risk of side effects.

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  • Grapefruit or grapefruit juice: Avoid grapefruit products while taking Reluease Tablet 10's, as they may affect how Reluease Tablet 10's is broken down and increase its levels in your body.

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Habit Forming

No

Therapeutic Class

[MISCELLANEOUS]

FAQs

Reluease Tablet 10's is used to treat heavy menstrual bleeding caused by uterine fibroids in premenopausal women.
Reluease Tablet 10's helps reduce hormone levels that contribute to fibroid symptoms and provides low-dose estrogen and progesterone to maintain hormonal balance and protect bones.
Hormonal contraceptives should not be used together with Reluease Tablet 10's. It is advised to inform your doctor before starting treatment with Reluease Tablet 10's.
Reluease Tablet 10's may decrease bone density, which may increase the chances of fractures or broken bones. Talk to the doctor about the risks and how to prevent them.
Many women notice improvement in bleeding within the first few weeks, but the response may vary from person to person.
Reluease Tablet 10's may cause side effects like hot flashes, decreased sexual interest, headache, hair loss, night sweats, and mood changes.If you have a history of liver disease, inform the doctor before receiving Reluease Tablet 10's. If you notice any side effects that are not manageable, please consult your doctor.
Many women notice a reduction in heavy menstrual bleeding within the first month of starting treatment. Pain relief from endometriosis may also begin within the first few weeks, though it can take up to several months to achieve full benefits. Talk to your doctor if your symptoms do not improve after a few weeks.
Irregular bleeding, spotting, or changes in your menstrual cycle are common during the first few months of taking Reluease Tablet 10's. However, if you experience unusually heavy, continuous, or worsening vaginal bleeding, you should notify your healthcare provider. Consult your doctor about any bleeding concerns.
Moderate alcohol consumption is generally acceptable, but excessive drinking can increase your risk of liver strain and make symptoms like hot flashes worse. It is best to discuss your alcohol intake with your healthcare provider.
Do not take Reluease Tablet 10's if you have uncontrolled or severe high blood pressure, as hormones can elevate blood pressure further and increase the risk of cardiovascular events. If your blood pressure is well-controlled, your doctor will monitor it closely during treatment. Inform your doctor about your cardiovascular health.
It is very common for periods to stop entirely while taking Reluease Tablet 10's. However, because pregnancy is still possible, you should take a pregnancy test if your period stops and you suspect you might be pregnant. Consult your doctor if you have concerns about missed periods or pregnancy.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

Sun Pharmaceutical Industries Ltd., Sun House, Cts No. 201 B/1, Western Express Highway, Goregaon (E), Mumbai 400063
Other Info - REL0554
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