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compositionComposition:INTERFERON ALFA 2B-3MIU
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Prescription Medicine
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Reliferon 3MIU Injection is used for the treatment of Follicular cancer, Hairy cell carcinoma, Malignant melanoma, AIDS-Related Kaposi's Sarcoma, Hodgkin's Lymphoma, Chronic hepatitis B, and Chronic hepatitis C. It contains Interferon alpha 2b as an active ingredient, which belongs to the class of immunomodulators. It works by inhibiting the abnormal growth of cancer cells. On the other hand, it also helps reduce the amount of hepatitis C virus (HCV) in the body.

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Written By Dr. Lakshmithulasi Yarragunta , PharmD (PB)
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

INTERFERON ALFA 2B-3MIU

Manufacturer/Marketer :

Reliance Formulation Pvt Ltd

Consume Type :

Parenteral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Reliferon 3MIU Injection

Reliferon 3MIU Injection is a specialised injection prescribed to treat long-term viral infections, such as chronic hepatitis B and hepatitis C. It is also used in the treatment of certain types of cancer, including skin cancers like melanoma and specific blood cancers. By targeting these complex conditions, this medicine plays an important role in helping to manage disease progression and support long-term recovery.

Because this medication is highly specialised, it must be taken exactly according to the schedule prescribed by your healthcare provider. Consistency is key to keeping the level of the medicine stable in your body, which helps it work effectively. This medicine is injected and can be taken without regard to food, though staying well-hydrated is highly recommended during your treatment course.

While taking Reliferon 3MIU Injection , you may experience common side effects like flu-like symptoms, fever, and fatigue. These symptoms are generally manageable, but you must contact your doctor immediately if you experience serious side effects, such as severe changes in mood, vision changes, or signs of a serious infection. Your healthcare team is there to help you navigate these side effects safely.

Do not take this if you have a history of severe mental health issues, autoimmune hepatitis, or advanced liver damage. Before starting your treatment, you should discuss your complete medical history with your doctor, especially if you have heart disease, kidney issues, or thyroid conditions. This allows your provider to ensure the medicine is safe for your specific health profile.

This medicine can interact with other substances, including alcohol, which should be avoided because it can put extra strain on your liver. It is also important to tell your doctor about all other medicines you are taking, especially those that affect your immune system. If you are pregnant, planning to become pregnant, breastfeeding, or are an older adult, consult your doctor to discuss the risks and benefits before starting this treatment.

Uses of Reliferon 3MIU Injection

Reliferon 3MIU Injection is used to treat certain viral infections and cancers by helping your immune system fight disease and slow the growth of abnormal cells. It may be prescribed for the following conditions:

  • Chronic Hepatitis B: Reliferon 3MIU Injection helps the body's immune system fight the hepatitis B virus, which slows down the virus's ability to multiply and protects the liver from long-term damage.
  • Chronic Hepatitis C: Reliferon 3MIU Injection boosts your natural immune response to help clear the hepatitis C virus from your bloodstream, reducing the risk of permanent liver scarring.
  • Malignant Melanoma: Reliferon 3MIU Injection is used as an additional therapy after surgery to help delay or prevent this serious type of skin cancer from returning or spreading.
  • Certain Leukaemias and Lymphomas: Reliferon 3MIU Injection helps slow down or stop the rapid division and growth of abnormal white blood cells in conditions like hairy cell leukaemia.

Key Benefits

Reliferon 3MIU Injection provides important benefits by helping control viral infections and slowing the progression of certain cancers, including:

  • Helps protect long-term liver health: By controlling chronic hepatitis B and C infections, it reduces ongoing liver inflammation and lowers the risk of complications such as liver scarring, cirrhosis, and liver failure.
  • Supports cancer treatment: It helps slow the growth and spread of abnormal cancer cells, improving the effectiveness of overall cancer management and reducing the risk of disease progression.
  • Strengthens the body's immune response: By enhancing your natural immune defences, Reliferon 3MIU Injection helps your body fight viruses and abnormal cells more effectively, supporting better long-term treatment outcomes.
Side effects of Reliferon 3MIU Injection 0.5 ml
Here's a comprehensive approach to managing medication-triggered fever:
  • Inform your doctor immediately if you experience a fever after starting a new medication.
  • Your doctor may adjust your medication regimen or dosage as needed to minimize fever symptoms.
  • Monitor your body temperature to monitor fever progression.
  • Drink plenty of fluids, such as water or electrolyte-rich beverages, to help your body regulate temperature.
  • Get plenty of rest and engage in relaxation techniques, such as deep breathing or meditation, to help manage fever symptoms.
  • Under the guidance of your doctor, consider taking medication, such as acetaminophen or ibuprofen, to help reduce fever.
  • If your fever is extremely high (over 103°F), or if you experience severe symptoms such as confusion, seizures, or difficulty breathing, seek immediate medical attention.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Rest well; get enough sleep.
  • Wear comfortable layers of clothes and get to a warm place.
  • Drink warm fluids like coffee, tea or hot chocolate.
  • Warm up using a blanket or heating pad.
Here are the step-by-step strategies to manage the side effects of " Muscle Pain" caused by medication usage:
  • Report to Your Doctor: Inform your doctor about the muscle pain, as they may need to adjust your medication.
  • Stretch Regularly: Gentle stretching can help relieve muscle pain and stiffness.
  • Stay Hydrated: Adequate water intake supports muscle health by removing harmful substances and maintaining proper muscle function.
  • Warm or Cold Compresses: Apply cold or warm compresses to the affected area to reduce pain and inflammation.
  • Rest and Relaxation: Adequate rest helps alleviate muscle strain, while relaxation techniques like deep breathing and meditation can soothe muscle tightness, calm the mind, and promote relief from discomfort.
  • Gentle Exercise: Participate in low-impact activities, such as yoga or short walks, to improve flexibility, reduce muscle tension, and alleviate discomfort.
  • Consult a physician: If your symptoms don't improve or get worse, go to the doctor for help and guidance.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
  • Try eating smaller meals (4-5 times) instead of large ones to make it easier on your stomach.
  • Avoid foods that are spicy, fatty, or high in insoluble fibre.
  • Consuming soluble fibre (such as psyllium) can help with constipation, and probiotics may reduce bloating and discomfort.
  • Stay away from carbonated drinks, alcohol, caffeine, and smoking, as they can upset your stomach.
  • Reducing stress, losing weight, and exercising regularly for 20-30 minutes can help improve digestion and reduce stomach issues.
  • Poor sleep can worsen stomach problems, so focus on good sleep habits or use tools like Sleepio to improve your sleep.

Directions for Use

  • Follow your doctor’s instructions on the dosage and timing of this medication.
  • Reliferon 3MIU Injection will be administered by a doctor or nurse in a healthcare facility.
  • Do not self-administer.

How Reliferon 3MIU Injection Works

Reliferon 3MIU Injection contains interferon alfa-2b, an immunomodulatory medicine that helps the body's immune system fight certain viral infections and some types of cancer. Interferon alfa-2b works by attaching to specific receptors on the surface of cells and triggering a series of protective responses within the body. These responses help prevent viruses from multiplying and spreading to healthy cells, allowing the immune system to control the infection more effectively. Interferon alfa-2b also helps slow the growth and multiplication of certain cancer cells. In addition, it stimulates the immune system to recognise and destroy infected or abnormal cells, enhancing the body's natural defence against disease. Together, these actions help control viral infections, slow the progression of certain cancers, and strengthen the body's immune response.
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Alcohol

Caution

It is unknown whether Reliferon 3MIU Injection interacts with alcohol. Consult your doctor for more information.

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Pregnancy

Unsafe

Reliferon 3MIU Injection is not recommended for use in pregnancy as it may cause fetal toxicity and harm your foetus. Hence, if you are pregnant or planning to be pregnant, inform your doctor before receiving Reliferon 3MIU Injection .

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Breast Feeding

Unsafe

Reliferon 3MIU Injection should not be taken if you are breastfeeding, as it passes into breast milk and may harm your infant. Avoid nursing your child while on treatment with this medicine.

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Driving

Caution

Reliferon 3MIU Injection will be administered to hospitalized patients. Driving is not recommended.

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Liver

Caution

If you have a pre-existing or a history of liver disease, inform your doctor before receiving Reliferon 3MIU Injection . Reliferon 3MIU Injection may cause liver impairment. Hence, inform your doctor if you observe any symptoms such as jaundice, dark-coloured urine, or nausea. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Kidney

Caution

Limited data are available on the effect of Reliferon 3MIU Injection in kidney-impaired patients. If you have a pre-existing or a history of kidney disease, inform your doctor.

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Children

Unsafe

Reliferon 3MIU Injection is not recommended for use in children below 18 years as the safety and efficacy are not established.

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Heart

Caution

Reliferon 3MIU Injection may worsen heart conditions like arrhythmias or chest pain, so it's risky for cardiac patients. Always consult your doctor before starting, especially if you have a history of heart disease.

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Geriatrics

Caution

Reliferon 3MIU Injection can be used in elderly patients, but with caution due to age-related issues like kidney, liver, or heart problems. Your doctor may adjust the dose and monitor you closely to ensure safety.

What if I have taken an overdose of Reliferon 3MIU Injection

If you suspect an accidental overdose or if someone has accidentally injected too much of this medicine, seek emergency medical attention or contact a poison control centre immediately.

Diet & Lifestyle Advise

  • Stay well hydrated: Drink plenty of water and other fluids, especially on the days you receive your injection, to help reduce flu-like symptoms and support kidney function.
  • Eat small, nutritious meals: Choose small, frequent, nutrient-rich meals if you experience nausea or a reduced appetite to help maintain your energy levels and nutritional status.
  • Avoid alcohol: Do not consume alcohol during treatment, as it can place additional stress on your liver and increase the risk of liver damage.
  • Time your injections appropriately: If approved by your doctor, schedule your injections close to bedtime so you may sleep through the temporary flu-like side effects.
  • Allow yourself adequate rest: Prioritise sleep and avoid strenuous physical activities when you feel tired, giving your body enough time to recover during treatment.
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How Soon It Starts Working

The time required for Reliferon 3MIU Injection to start to work: Reliferon 3MIU Injection ideally starts working within 3-12 hours of intramuscular or subcutaneous dose and 30 minutes followed by an intravenous administration. The time for which the effects of Reliferon 3MIU Injection last: The duration of action for Reliferon 3MIU Injection is unknown.

What if you forget to take Reliferon 3MIU Injection

If you miss a dose, contact your doctor or pharmacist immediately to get personalised guidance on when to take your next injection. Do not inject a double dose to make up for a missed one.

Storage

•Store Reliferon 3MIU Injection in the refrigerator between 2°C and 8°C (36°F to 46°F).•Do not freeze this medication, and do not use any vial or syringe that has been frozen.
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Keep Refrigerated. Do not freeze.Prepaid payment required.

Drug Warnings

  • Inspect the solution before use: Always check that the solution is clear and colourless before injecting. Do not use it if it appears cloudy, discoloured, or contains visible particles.
  • Rotate injection sites: Use a different injection site for each dose, such as alternating between your thigh and abdomen, to help prevent skin irritation, soreness, or scarring.
  • Use new needles and syringes every time: Never reuse needles or syringes, as this increases the risk of serious infections and blood-borne diseases.
  • Watch for mood changes: Monitor your mood closely and ask a family member or caregiver to watch for changes. Contact your doctor immediately if you develop persistent sadness, anxiety, irritability, or thoughts of self-harm.
  • Attend regular blood tests: Keep all scheduled monitoring appointments so your doctor can regularly check your blood cell counts, liver function, and thyroid health during treatment.

Drug-Drug Interactions

verifiedApollotooltip

The following medicines may interact with Reliferon 3MIU Injection and require close monitoring or dose adjustments:

  • Immunosuppressive medicines (including certain chemotherapy medicines): Using these medicines together may increase the risk of serious side effects and affect how well your immune system functions.
  • Theophylline: Reliferon 3MIU Injection may increase the levels of theophylline in your blood, raising the risk of toxicity.
  • Certain antiviral medicines: Combining these medicines may increase the risk of nerve damage or other neurological side effects.
Interferon alfa-2bBaricitinib
Severe
Interferon alfa-2bEltrombopag
Severe

Drug-Drug Interactions

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Interferon alfa-2bBaricitinib
Severe
How does the drug interact with Reliferon 3MIU Injection 0.5 ml:
Coadministration of Reliferon 3MIU Injection 0.5 ml with Baricitinib can increase the risk of developing serious infections.

How to manage the interaction:
Taking Baricitinib with Reliferon 3MIU Injection 0.5 ml together can result in an interaction, but it can be taken if your doctor has advised it. However, consult a doctor if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning when you urinate. Do not stop using any medications without a doctor's advice.
Interferon alfa-2bEltrombopag
Severe
How does the drug interact with Reliferon 3MIU Injection 0.5 ml:
When Reliferon 3MIU Injection 0.5 ml is taken with Eltrombopag, it can lower the metabolism of Eltrombopag.

How to manage the interaction:
There may be a possibility of interaction between Eltrombopag and Reliferon 3MIU Injection 0.5 ml, but it can be taken if prescribed by a doctor. If you have any of these symptoms, it's important to call a doctor right away. These symptoms include chronic hepatitis C, advanced liver disease, cirrhosis, liver failure, and other liver-related problems. You should also seek medical attention if you experience confusion, fever, joint pain, swelling, or any other unusual symptoms. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip

Be aware of the following food and drink interaction while using Reliferon 3MIU Injection :

  • Alcohol: Avoid alcohol during treatment, as it can significantly increase the risk of liver damage.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[ANTINEOPLASTIC]

FAQs

Reliferon 3MIU Injection is used to treat Follicular cancer, Hairy cell carcinoma, Malignant melanoma, AIDS-Related Kaposi’s Sarcoma, Hodgkin’s Lymphoma, Chronic hepatitis B, and Chronic hepatitis C
Reliferon 3MIU Injection contains Interferon alpha 2b, which works by inhibiting the abnormal growth of cancer cells. It also helps reduce the amount of hepatitis C virus (HCV) in the body.
Reliferon 3MIU Injection is injected under the skin (subcutaneously) or into a muscle. Your doctor or nurse will train you on how to prepare and inject it safely at home. Talk to your doctor or pharmacist if you have any questions about the injection process.
Flu-like symptoms are very common, especially during the first few weeks of treatment. Your doctor may suggest taking an over-the-counter pain reliever like acetaminophen before your injection to help manage these symptoms. Talk to your doctor or pharmacist before starting any new over-the-counter medicines.
No, you should avoid alcohol while using this medicine. Alcohol can increase the risk of liver damage and can make side effects like dizziness and fatigue much worse. Talk to your doctor if you have questions about avoiding alcohol.
Yes, this medication can cause significant mood changes, including severe depression, anxiety, and irritability. It is very important to have someone monitor your mood. If you begin to feel unusually sad or have thoughts of self-harm, contact your doctor immediately.
No, this medicine is generally not recommended during pregnancy because it may harm the unborn baby. Both men and women should use effective birth control while using this medicine. Talk to your doctor or pharmacist if you are pregnant, planning a pregnancy, or breastfeeding.
The length of your treatment depends entirely on the specific viral infection or type of cancer being treated. Your doctor will determine how long you need to take it based on regular medical checkups and blood test results.
Do not inject a double dose to make up for a missed one. Contact your healthcare provider or pharmacist right away to receive specific instructions on how to safely adjust your schedule.
Yes, this medicine must be kept in the refrigerator between 2°C and 8°C (36°F to 46°F). Never freeze it, and keep it in its original packaging to protect it from light. Talk to your doctor or pharmacist if you need tips on how to travel safely with this medicine.

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Country of origin

INDIA

Manufacturer/Marketer address

Dhirubhai Ambani Life Sciences Centre, R-282, TTC Area of MIDC, Thane-Belapur Road, Rabale, Navi Mumbai 400 701
Other Info - REL0209
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