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  3. Ranolaz OD Tablet 10's

Ranolaz OD Tablet 10's, Pack of 10 TABLETS
Ranolaz OD Tablet 10's, Pack of 10 TABLETS
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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Ranolaz OD Tablet is used alone or with other medicines to treat angina pectoris. It helps prevent any further attack of angina by making the heart work more efficiently, and it is used as an add-on to existing treatment in patients whose disease is not adequately controlled by other medicines for angina pectoris, such as beta-blockers or calcium antagonists, or in patients who cannot take these medicines. In some cases, it may cause side effects such as constipation, dizziness, headache, or feeling sick. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Composition :

RANOLAZINE-1000MG

Manufacturer/Marketer :

Torrent Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Ranolaz OD Tablet

Ranolaz OD Tablet is used to treat angina pectoris. Angina pectoris is discomfort in the chest or chest pain, which generally occurs due to coronary artery disease (CAD) when the heart and its muscles are not receiving enough oxygen and blood.

Ranolaz OD Tablet contains Ranolazine, which reduces sodium ions flow into the heart muscle cells. This interferes with the activity of special channels on the cell surface called 'sodium-dependent calcium channels, through which calcium ions normally enter the cells.

You may sometimes experience constipation, dizziness, headache, or feeling sick. Most of these side effects of Ranolaz OD Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

You can take Ranolaz OD Tablet with food or as advised by your doctor. It should be swallowed whole with a glass of water. Do not chew, bite, or break it. Depending on your medical conditions, your doctor will advise the dose and duration of Ranolaz OD Tablet .

Do not take Ranolaz OD Tablet if you are allergic to any component in this medicine. Ranolaz OD Tablet should not be stopped even if you feel better for the best results, as it prevents any future harm. If you stop taking the Ranolaz OD Tablet on your own, your chest pain can come back in more severe form. If you plan to get pregnant or are pregnant or breastfeeding, please consult your doctor to avoid any unwanted harm to the baby. 

Uses of Ranolaz OD Tablet

Ranolaz OD Tablet used in the treatment of Angina Pectoris. The detailed use of Ranolaz OD Tablet is as follows:

Treatment of Angina Pectoris: Ranolaz OD Tablet is used in the treatment of angina pectoris by improving oxygen supply to the heart muscle and enhancing cardiac efficiency, particularly in areas with fixed epicardial lesions, thereby decreasing chest pain episodes and improving patient quality of life.

Directions for Use

• Ranolaz OD Tablet can be taken with or without food. Avoid consuming grapefruit or grapefruit juice while taking ths medication. • It is usually taken twice daily at the same time each day or as prescribed by your doctor. • Swallow Ranolaz OD Tablet as a whole with a glass of water. • Do not chew, crush, or break it.

Medicinal Benefits

  • Ranolaz OD Tablet is prescribed for treating angina. Ranolaz OD Tablet is an anti-anginal medication used to treat angina pectoris.
  • It reduces sodium ions' flow into the heart muscle cells. This interferes with the activity of special channels on the cell surface called ‘sodium-dependent calcium channels’ through which calcium ions normally enter the cells.
  • This medicine reduces the number of calcium ions that enter the cells. Calcium ions normally cause the heart muscle to contract.
  • Ranolaz OD Tablet helps improve blood flow to the heart muscle and relieve the symptoms of angina pectoris.

How Ranolaz OD Tablet Works

The active substance in Ranolaz OD Tablet is Ranolazine, which reduces sodium ions flow into the heart muscle cells. This interferes with the activity of special channels on the cell surface called 'sodium-dependent calcium channels, through which calcium ions normally enter the cells. This reduces the number of calcium ions that enter the cells. Calcium ions normally cause the heart muscle to contract. By reducing the flow of calcium into the cells, Ranolaz OD Tablet is thought to help the heart relax, improving blood flow to the heart muscle and relieving the symptoms of angina pectoris.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Ranolaz OD Tablet
Here are the steps to cope with constipation as a side effect of medication:
  • Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
  • Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
  • Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
  • Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
  • Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
  • Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.

What if I have taken an overdose of Ranolaz OD Tablet

Do not take more than the prescribed dose of Ranolaz OD Tablet as it may cause overdose. The symptoms of overdose include nausea, vomiting, confusion, dizziness, double vision, fainting, difficulty speaking, uncontrollable shaking of a part of the body, hallucinations and burning, pain, numbness, or tingling in any part of the body. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

  • Do not take Ranolaz OD Tablet if you are allergic to any component in this medicine.
  • Ranolaz OD Tablet should not be stopped even if you feel better for the best results, as it prevents any future harm. If you stop taking the Ranolaz OD Tablet on your own, your chest pain can come back in a more severe form.
  • Ranolaz OD Tablet should be taken with caution in liver disease, kidney disease, or heart problems.
  • Inform your doctor if you are pregnant, planning for pregnancy, or breastfeeding before taking Ranolaz OD Tablet .
  • Also, grapefruit juice should be avoided while taking Ranolaz OD Tablet .
  • As a precautionary measure, avoid junk food items from outside and stick to freshly prepared home-cooked meals for a speedy recovery.
  • Do regular exercise to avoid abdominal heaviness.

Drug-Drug Interactions

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RanolazineEfavirenz
Critical
RanolazineArmodafinil
Critical

Drug-Drug Interactions

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RanolazineEfavirenz
Critical
How does the drug interact with Ranolaz OD Tablet:
When Efavirenz is taken with Ranolaz OD Tablet, it can lower the levels of Ranolaz OD Tablet.

How to manage the interaction:
Taking Ranolaz OD Tablet with Efavirenz is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medication without consulting a doctor.
RanolazineArmodafinil
Critical
How does the drug interact with Ranolaz OD Tablet:
When Armodafinil is taken with Ranolaz OD Tablet, the metabolism of Ranolaz OD Tablet can be increased when combined with Armodafinil.

How to manage the interaction:
Taking Ranolaz OD Tablet with Armodafinil is not recommended as it can result in an interaction, but it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
RanolazinePrimidone
Critical
How does the drug interact with Ranolaz OD Tablet:
Coadministration of Ranolaz OD Tablet with primidone can reduce the blood levels and effects of Ranolaz OD Tablet.

How to manage the interaction:
Although there is an interaction between Primidone and Ranolaz OD Tablet, it can be taken if prescribed by a doctor. However, if you experience any unusual symptoms, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
RanolazineEnzalutamide
Critical
How does the drug interact with Ranolaz OD Tablet:
Taking Enzalutamide may decrease the blood levels of Ranolaz OD Tablet, which may make Ranolaz OD Tablet less effective.

How to manage the interaction:
Taking Enzalutamide with Ranolaz OD Tablet is not recommended, as it may lead to an interaction, it can be taken if prescribed by the doctor. Do not discontinue any medications without a doctor's advice.
RanolazineZiprasidone
Critical
How does the drug interact with Ranolaz OD Tablet:
Co-administration of Ranolaz OD Tablet with Ziprasidone can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Ranolaz OD Tablet with Ziprasidone together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any symptoms such as sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not discontinue any medications without consulting a doctor.
RanolazinePentobarbital
Critical
How does the drug interact with Ranolaz OD Tablet:
When Ranolaz OD Tablet is taken with Pentobarbital, may significantly reduce the blood levels of Ranolaz OD Tablet, which may make the medication ineffective or less effective.

How to manage the interaction:
Taking Phenobarbital with Ranolaz OD Tablet can lead to an interaction, please consult a doctor before taking it. They can be taken together if advised by a doctor. However, contact a doctor if you experience any symptoms. Do not stop taking any medications without consulting a doctor.
RanolazineDexamethasone
Critical
How does the drug interact with Ranolaz OD Tablet:
When Dexamethasone is taken with Ranolaz OD Tablet, may significantly reduce the blood levels of Ranolaz OD Tablet.

How to manage the interaction:
Co-administration of Ranolaz OD Tablet and Dexamethasone can lead to an interaction, it can be taken if advised by a doctor. Do not stop using any medications without a doctor's advice.
RanolazineMesoridazine
Critical
How does the drug interact with Ranolaz OD Tablet:
Co-administration of Mesoridazine and Ranolaz OD Tablet may significantly increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Phenylbutazone with Ranolaz OD Tablet can lead to an interaction, please consult a doctor before taking it. They can be taken together if advised by a doctor. However, contact a doctor if you experience any symptoms such as dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop taking any medications without consulting a doctor.
RanolazineRifampicin
Critical
How does the drug interact with Ranolaz OD Tablet:
When Ranolaz OD Tablet is taken with rifampicin, it can reduce the blood levels and effects of Ranolaz OD Tablet.

How to manage the interaction:
Although there is an interaction between Ranolaz OD Tablet and rifampicin, they can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
RanolazineVoriconazole
Critical
How does the drug interact with Ranolaz OD Tablet:
Co-administration of Ranolaz OD Tablet together with Voriconazole may significantly increase the blood levels and effects of Ranolaz OD Tablet.

How to manage the interaction:
Taking Ranolaz OD Tablet with Voriconazole together can result in an interaction, but it can be taken if a doctor has advised it. Consult a doctor if you experience dizziness, or fast or pounding heartbeats. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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RANOLAZINE-1000MGGrapefruit and Grapefruit Juice
Severe

Drug-Food Interactions

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RANOLAZINE-1000MGGrapefruit and Grapefruit Juice
Severe
Common Foods to Avoid:
Grapefruit Juice, Grapefruit

How to manage the interaction:
Grapefruit juice can increase the levels of Ranolaz OD Tablet, and high blood levels of food can occasionally cause an irregular heart rhythm that may be serious. Grapefruit and grapefruit juice should be avoided while taking Ranolaz OD Tablet if possible.

Diet & Lifestyle Advise

  • Maintain a healthy lifestyle by exercising regularly, maintaining weight, and eating a healthy diet.
  • If you suffer from kidney or liver disease, please inform your doctor before taking the Ranolaz OD Tablet .
  • Alcohol consumption along with Ranolaz OD Tablet should be avoided as it may cause excessive drowsiness and increase muscle pain.

Habit Forming

No

Therapeutic Class

ANTIANGINALS

Ranolaz OD Tablet Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Safe if prescribed

Ranolaz OD Tablet does not have any reported interaction; hence, if you experience any difficulty, discuss with your doctor.

bannner image

Pregnancy

Unsafe

Ranolaz OD Tablet should not be used when pregnancy unless necessary. So, inform your doctor if you are pregnant or suspect pregnancy. Your doctor will weigh the benefits and potential risks before prescribing Ranolaz OD Tablet .

bannner image

Breast Feeding

Consult your doctor

Ranolaz OD Tablet should not be used in nursing mothers. Please consult the doctor if you have any concerns regarding this.

bannner image

Driving

Safe if prescribed

Ranolaz OD Tablet does not have any reported interaction; hence, in case you experience any difficulty, discuss with your doctor.

bannner image

Liver

Caution

Ranolaz OD Tablet to be taken with caution, especially if you have a history of liver disease. The dose may have to be adjusted by your doctor.

bannner image

Kidney

Caution

Ranolaz OD Tablet to be taken with caution, especially if you have a history of kidney disease. The dose may have to be adjusted by your doctor.

bannner image

Children

Unsafe

Ranolaz OD Tablet is not recommended for children below the age of 18. The safety and effectiveness of Ranolaz OD Tablet have not been established in children due to limited testing of this drug on children by competent authorities worldwide.

Have a query?

FAQs

Ranolaz OD Tablet is used alone or with other medicines to treat angina pectoris.

The active substance in Ranolaz OD Tablet is Ranolazine, which reduces sodium ions flow into the heart muscle cells. This interferes with the activity of special channels on the cell surface called sodium-dependent calcium channels through which calcium ions normally enter the cells. This reduces the number of calcium ions that enter the cells. Calcium ions normally cause the heart muscle to contract. By reducing the flow of calcium into the cells, Ranolaz OD Tablet is thought to help the heart to relax, improving blood flow to the heart muscle and relieving the symptoms of angina pectoris.

No, Ranolaz OD Tablet does not stop acute attacks (sudden attacks) of angina, but Ranolaz OD Tablet helps prevent a new attack.

No, alcohol should not be taken with Ranolaz OD Tablet as it may lead to unwanted side effects and increase angina attacks.

Yes, smoking (tobacco) decreases the efficacy of Ranolaz OD Tablet , especially when taken for angina (chest pain), so it should be avoided while taking Ranolaz OD Tablet .

Yes, Ranolaz OD Tablet can cause an upset stomach when taken empty stomach. So, to avoid it, Ranolaz OD Tablet should be taken with a meal for best results.

Yes, Ranolaz OD Tablet can cause drowsiness. If you feel excessively sleepy, please consult your doctor for better advice.

Some major side effects include a rapid, pounding, or irregular heartbeat, difficulty breathing, and fainting. If you encounter any of these symptoms, contact your doctor immediately.

Do not take more than the prescribed dose of Ranolaz OD Tablet as it may cause overdose. The symptoms of overdose include nausea, vomiting, confusion, dizziness, double vision, fainting, difficulty speaking, uncontrollable shaking of a part of the body, hallucinations and burning, pain, numbness, or tingling in any part of the body. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Ranolaz OD Tablet may increase the blood levels and effects of metoprolol. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. Contact your doctor if your condition changes or you experience increased side effects.

Ranolaz OD Tablet might raise metformin levels, increasing the risk of lactic acidosis. If you are prescribed ranolazine while taking metformin, discuss it with a healthcare physician. They may offer a lesser dose of metformin as a safer alternative.

You can take it if prescribed by the doctor. However, limit simvastatin to 20 mg once daily in individuals taking any dose of Ranolaz OD Tablet .

Country of origin

India

Manufacturer/Marketer address

Off. Ashram Road, Ahmedabad - 380 009., Gujarat, India
Other Info - RAN0076

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Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 31, 2025 | 11:29 AM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Reference

  1. https://www.medicines.org.uk/emc/files/pil.6442.pdf
  2. https://medlineplus.gov/druginfo/meds/a606015.html
  3. https://www.accessdata.fda.gov/drugsatfda_docs/label/2016/021526s029lbl.pdf
  4. https://www.ema.europa.eu/en/documents/product-information/ranexa-epar-product-information_en.pdf

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