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compositionComposition:ISONIAZID-300MG
prescription
Prescription Medicine
info
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PYZINA KID TABLET is used to treat and prevent tuberculosis (TB). It contains isoniazid, an antibiotic that works by preventing bacteria from producing mycolic acids, an enzyme required for cell wall formation (protective coating). As a result of the disturbance in their metabolism, bacteria that lack a cell wall die and burst. Thus, it inhibits the spread of infection by acting against the bacteria Mycobacterium tuberculosis, which causes tuberculosis.

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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

ISONIAZID-300MG

Manufacturer/Marketer :

Lupin Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About PYZINA KID TABLET

PYZINA KID TABLET is a prescription medicine used to treat and prevent tuberculosis (TB) in children. This antibiotic works by stopping the growth of the bacteria that cause this serious lung infection. It is a critical part of your child's treatment plan to ensure the infection is completely cleared from their body.

To get the best results, your child must take this medicine every single day at the exact same time. It is highly recommended to take this medicine on an empty stomach, either one hour before or two hours after a meal, as food can prevent the medicine from being absorbed properly. Ensuring your child eats a balanced, nutrient-rich diet can also help support their immune system during recovery.

While taking PYZINA KID TABLET, some children may experience mild side effects like a temporary loss of appetite or a mild upset stomach. However, you must contact your doctor immediately if you notice serious symptoms like unusual tiredness, dark urine, or yellowing of the eyes and skin. These symptoms require urgent medical evaluation.

Talk to your doctor before starting this medicine if your child has a history of liver disease, kidney issues, or nerve tingling. Do not take this if your child has had a severe allergic reaction to this medication in the past or has active liver damage.

This medicine can interact with certain other prescriptions, particularly seizure medicines, and can cause reactions when combined with specific foods like aged cheeses or certain fish. Always consult your paediatrician or pharmacist about all other medicines, vitamins, or supplements your child is currently taking.

Uses of PYZINA KID TABLET

PYZINA KID TABLET helps treat and prevent tuberculosis (TB) by killing or stopping the growth of tuberculosis bacteria. Your doctor may prescribe it for the following conditions:

  • Active Tuberculosis: PYZINA KID TABLET helps by killing the active bacteria causing the infection, curing the illness when used in combination with other prescribed tuberculosis medicines.
  • Latent Tuberculosis Prevention: PYZINA KID TABLET helps prevent inactive tuberculosis bacteria already in the child's body from turning into an active, harmful infection.

Key Benefits

Using PYZINA KID TABLET as prescribed helps treat or prevent tuberculosis (TB) in children. Here are the key benefits you can expect:

  • Treats tuberculosis effectively: Helps eliminate tuberculosis bacteria from the body when used as part of combination therapy, supporting complete recovery from active TB.
  • Helps prevent active tuberculosis: Reduces the risk of inactive tuberculosis bacteria developing into active disease in children with latent TB infection.
  • Easy for children to take: The child-friendly dispersible tablet is easy to administer, helping ensure accurate dosing and better treatment adherence.

Directions for Use

  • PYZINA KID TABLET should be administered at least 30 minutes before a meal or 2 hours after a meal as directed by the doctor.
  • Follow your doctor’s instructions on the dosage and timing of this medication to ensure safety.
  • Disperse the tablet in the suggested amount of water and give the mixture to your child using an oral syringe or measuring cup.
  • Do not store the mixture for later use.

How PYZINA KID TABLET Works

PYZINA KID TABLET contains isoniazid, an anti-tuberculosis medicine.It works by blocking the production of mycolic acid, a fatty substance that forms an essential part of the protective cell wall of Mycobacterium tuberculosis. Without enough mycolic acid, the bacteria cannot survive or multiply properly. Without a protective cell wall, the bacteria cannot grow or multiply, allowing the body's immune system to eliminate the infection more effectively. When used as prescribed, PYZINA KID TABLET helps treat active tuberculosis and prevents latent tuberculosis infection from progressing to active disease.
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Alcohol

Not applicable

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Pregnancy

Not applicable

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Breast Feeding

Not applicable

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Driving

Not applicable

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Liver

Caution

If your child has liver problems, inform your doctor before using PYZINA KID TABLET. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your child’s health condition.

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Kidney

Caution

If your child has kidney problems, inform your doctor before using PYZINA KID TABLET. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your child’s health condition.

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Children

Safe if prescribed

Use PYZINA KID TABLET for children as prescribed by the paediatrician.

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Heart

Consult your doctor

Please consult your doctor before giving PYZINA KID TABLET to your child. Your doctor will prescribe PYZINA KID TABLET if the benefits outweigh the risks.

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Geriatrics

Not applicable

PYZINA KID TABLET is for paediatric patients only.

What if I have taken an overdose of PYZINA KID TABLET

If you suspect your child has taken more than the prescribed amount of this medicine, seek immediate emergency medical attention.

Diet & Lifestyle Advise

  • Give Vitamin B6 (pyridoxine) supplements: This medicine can lower the levels of Vitamin B6 in your child's body, which may lead to nerve tingling. Ask your doctor about giving a daily B6 supplement to prevent this issue.
  • Avoid excessive amounts of certain foods: Foods rich in tyramine or histamine, such as aged cheeses, soy sauce, yeast extracts, tuna, and some tropical fish, may occasionally cause flushing, sweating, headache, or a rapid heartbeat while taking this medicine. These reactions are uncommon at usual doses, but it is sensible to avoid large amounts of these foods during treatment.
  • Encourage regular meals: Provide healthy, high-protein meals to help support your child's body as it fights the infection and heals.
  • Keep your child hydrated: Encourage your child to drink plenty of fluids throughout the day to support kidney and liver function.
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How Soon It Starts Working

The time required for PYZINA KID TABLET to start to work: The onset time of PYZINA KID TABLET has not been clinically established. The time for which the effects of PYZINA KID TABLET last: The duration of PYZINA KID TABLET’s effect is clinically not established.

What if you forget to take PYZINA KID TABLET

If you forget to give a dose, give it as soon as you remember. However, if it is almost time for your child's next scheduled dose, skip the missed dose and continue with the regular schedule. Do not give two doses at the same time to make up for a missed one.

Storage

•Store PYZINA KID TABLET at room temperature between 20°C and 25°C. •Keep the tablets in their original packaging with the container tightly closed to protect them from moisture and direct sunlight.

Drug Warnings

  • Check the tablets before use: Do not use the dispersible tablets if they appear damp, broken, or crumbled.
  • Complete the full course: Continue giving PYZINA KID TABLET exactly as prescribed, even if your child feels better. Stopping treatment too early may cause the infection to return and become more difficult to treat.
  • Monitor for unusual symptoms: Watch for unusual tiredness, weakness, yellowing of the skin or eyes, dark urine, or any changes in your child's behaviour, and contact your doctor if these occur.
  • Attend follow-up appointments: Keep all scheduled medical appointments and blood tests so your doctor can monitor your child's response to treatment and liver function.
  • Check before giving other medicines: Consult your doctor or pharmacist before giving your child any over-the-counter cough, cold, or pain medicines, as they may interact with PYZINA KID TABLET.

Drug-Drug Interactions

verifiedApollotooltip
  • Seizure medicines (such as phenytoin or carbamazepine): PYZINA KID TABLET may increase the levels of these medicines in the blood, raising the risk of side effects. Your doctor may monitor their levels or adjust the dose if needed.
  • Blood thinners (such as warfarin): PYZINA KID TABLET may affect how these medicines work, increasing the risk of bleeding or reducing their effectiveness. Regular monitoring may be required.
  • Sedatives (such as diazepam): Taking these medicines with PYZINA KID TABLET may increase their effects and side effects, including excessive drowsiness.
  • Other anti-tuberculosis medicines: When used together, some tuberculosis medicines may increase the risk of liver problems. Your doctor will monitor liver function during treatment.
PyrazinamideLomitapide
Severe
PyrazinamideLeflunomide
Severe

Drug-Drug Interactions

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PyrazinamideLomitapide
Severe
How does the drug interact with Pyzina Kid Tablet:
Co-administration of Lomitapide with Pyzina Kid Tablet may increase in the risk or severity of liver problems.

How to manage the interaction:
Although taking Lomitapide and Pyzina Kid Tablet together can evidently cause an interaction, it can be taken if a doctor has suggested it. If you have any of these symptoms, it's important to contact your doctor immediately: fever, chills, joint pain, swelling, bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark-colored urine, or bleeding. Do not stop using any medications without a doctor's advice. Do not discontinue the medication without consulting a doctor.
PyrazinamideLeflunomide
Severe
How does the drug interact with Pyzina Kid Tablet:
Co-administration of leflunomide with Pyzina Kid Tablet may increase the risk or severity of liver problems.

How to manage the interaction:
Although taking Leflunomide and Pyzina Kid Tablet together can cause an interaction, they can be taken together if prescribed by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, or yellowing of the skin or eyes, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
PyrazinamideRifampicin
Severe
How does the drug interact with Pyzina Kid Tablet:
Taking rifampicin together with Pyzina Kid Tablet can cause liver problems.

How to manage the interaction:
Although there is an interaction between Pyzina Kid Tablet and rifampicin, they can be taken together if prescribed by a doctor. However, if you experience fever, rash, less desire to eat, nausea, vomiting, fatigue, right upper abdominal pain, or dark urine, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
PyrazinamideKetoconazole
Severe
How does the drug interact with Pyzina Kid Tablet:
Co-administration of Ketoconazole with Pyzina Kid Tablet may increase the risk or severity of liver damage.

How to manage the interaction:
Although taking Ketoconazole and Pyzina Kid Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you have any of the following symptoms: fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, fatigue, lack of appetite, nausea, vomiting, abdominal pain, dark urine, light stools, and/or yellowing of the skin or eyes, consult a doctor immediately. Do not discontinue the medication without consulting a doctor.
PyrazinamideTeriflunomide
Severe
How does the drug interact with Pyzina Kid Tablet:
Co-administration of Teriflunomide with Pyzina Kid Tablet may increase the risk or severity of liver damage.

How to manage the interaction:
Although taking Teriflunomide and Pyzina Kid Tablet together can evidently cause an interaction, it can be taken if a doctor has suggested it. If you have any of these symptoms, it's important to contact your doctor immediately: fever, chills, joint pain, swelling, bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark-colored urine, or bleeding. Do not stop using any medications without a doctor's advice. Do not discontinue the medication without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip
  • Foods high in tyramine (such as aged cheese): Eating large amounts of these foods while taking PYZINA KID TABLET may occasionally cause flushing, headache, sweating, a rapid heartbeat, or raised blood pressure. This interaction is uncommon at standard doses.
  • Foods high in histamine (such as tuna, mackerel, and other poorly stored fish): Combining these foods with PYZINA KID TABLET may occasionally increase the risk of flushing, headache, sweating, itching, or a rapid heartbeat. Limiting large amounts of these foods during treatment may help reduce this risk.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTI- TUBERCULOSIS]

FAQs

PYZINA KID TABLET is used to treat and prevent tuberculosis (TB). PYZINA KID TABLET is used in combination with other anti-tuberculosis agents.
PYZINA KID TABLET contains isoniazid, an antibiotic used to treat and prevent tuberculosis. PYZINA KID TABLET prevents bacteria from producing mycolic acids, which are required for the formation of cell walls (protective coating). Additionally, PYZINA KID TABLET may combine with an enzyme that interferes with bacterial cell metabolism. Bacteria die as a result of the disruption in their metabolism and the lack of a cell wall. As a result, it kills Mycobacterium tuberculosis bacteria that causes tuberculosis (TB) and eliminates the infection.
You are recommended to avoid giving foods containing histamine or tyramine such as cured meat, matured cheese, soya, tuna, salmon, and mackerel to your child as they may interact with PYZINA KID TABLET and cause adverse effects such as sweating, headache, dizziness, light-headedness, flushing (reddening of the skin), fainting due to low blood pressure, uneven, fast or forceful heartbeat.
It is best to give PYZINA KID TABLET on an empty stomach, either 1 hour before or 2 hours after a meal, as this helps the body absorb the medicine properly. If the medicine causes an upset stomach, talk to your doctor or pharmacist.
If your child vomits shortly after taking their dose, do not give them another dose right away. Contact your paediatrician or pharmacist to get specific instructions on whether to repeat the dose.
This medicine can lower Vitamin B6 levels in the body, which can cause nerve tingling or numbness in the hands and feet. Giving a Vitamin B6 supplement helps prevent this. Talk to your doctor to see if your child needs a supplement.
Place the disintegrating tablet directly on your child's tongue and let it dissolve completely before they swallow. If needed, you can dissolve it in a small spoon of water as directed by your pharmacist.
Watch for yellowing of your child's skin or the whites of their eyes, dark urine, severe tiredness, loss of appetite, or severe stomach pain. If you notice any of these signs, stop the medicine and call your doctor right away.
Give the missed dose as soon as you remember. If it is almost time for the next scheduled dose, skip the missed one and stick to the regular schedule. Never give a double dose to make up for a missed one. Talk to your doctor if you miss multiple doses.
No. The food interaction with PYZINA KID TABLET is uncommon at the doses usually prescribed for children. Your child does not need to avoid all cheese or fish, but it is best to avoid large amounts of aged cheeses and poorly stored fish during treatment. Talk to your doctor or dietitian if you are unsure which foods are suitable.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

Lupin Ltd, 3rd floor Kalpataru Inspire, Off. W E Highway, Santacruz (East), Mumbai 400 055. India Country of Origin: India
Other Info - PYZ0004
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