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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy

Pylosak-Kit Combikit Tablet 6's is used to treat peptic ulcer disease caused by Helicobacter pylori infection. It kills the bacteria (Helicobacter pylori) causing the infection and reduces the production of stomach acid. It may cause side effects such as headache, diarrhoea, stomach pain, constipation, flatulence, nausea (feeling unwell), vomiting (being sick), skin rash, difficulty sleeping, changes in taste sensation, indigestion, and excessive sweating.

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Whats That

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Synonym :

AMOXICILLIN TRIHYDRATE+CLARITHROMYCIN+ESOMEPRAZOLE MAGNESIUM TRIHYDRATE

Manufacturer/Marketer :

Saksham Pharmaceuticals India Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Pylosak-Kit Combikit Tablet 6's

Pylosak-Kit Combikit Tablet 6's is an Antacid used to treat peptic ulcer disease caused by Helicobacter pylori infection. Helicobacter pylori is a type of bacteria that infects the stomach and leads to excess acid production. This effect leads to the formation of sores or ulcers in the stomach lining, known as peptic ulcer disease. Symptoms include stomach pain or discomfort, loss of appetite, weight loss, difficulty swallowing, bloating, nausea, and vomiting.  

Pylosak-Kit Combikit Tablet 6's is a combination medicine that contains Clarithromycin, Esomeprazole, and Amoxicillin. Clarithromycin is an antibiotic that kills the bacteria (Helicobacter pylori) causing the infection. Esomeprazole is a proton pump inhibitor and acts by reducing the production of stomach acid. Amoxicillin is a penicillin antibiotic and bactericidal (kills the bacteria). It works by preventing the formation of the bacterial cell covering (protective cell wall) necessary for their survival. Together, Pylosak-Kit Combikit Tablet 6's helps to treat peptic ulcer disease effectively.

Pylosak-Kit Combikit Tablet 6's is available in the form of tablets. Take this medicine exactly as prescribed by your doctor. Pylosak-Kit Combikit Tablet 6's may cause side effects such as headache, diarrhoea, stomach pain, constipation, flatulence, nausea (feeling sick), vomiting (being sick), skin rash, difficulty sleeping, changes in the sense of taste, indigestion, and excessive sweating. These side effects typically resolve on their own without requiring medical attention. However, if any of these side effects persist or worsen, consult your doctor immediately.

Do not take Pylosak-Kit Combikit Tablet 6's if you are allergic to Esomeprazole, Clarithromycin, Amoxicillin, other antibiotics (especially penicillin), other proton pump inhibitors (pantoprazole, lansoprazole, or omeprazole, etc.), or any other contents of it. Before taking Pylosak-Kit Combikit Tablet 6's, inform your doctor if you have arrhythmias (a condition with irregular heartbeat), hypokalemia (low potassium levels in the blood), severe liver failure, severe kidney problems, heart problems, urination problems, glandular fever (fever, sore throat, swollen glands, and extreme tiredness), lymphatic leukaemia (a type of blood cancer), HIV, and undergoing a blood test for chromogranin A levels (for cancers associated with endocrine (hormonal) and nervous system). Also, inform your doctor if you are pregnant or breastfeeding. Pylosak-Kit Combikit Tablet 6's should be used with caution in children and may require dose adjustments. Older people may not require any dose adjustments while using Pylosak-Kit Combikit Tablet 6's. Do not take alcohol, as it may worsen the side effects. Pylosak-Kit Combikit Tablet 6's may cause dizziness in some patients, so do not drive or operate heavy machinery if you feel dizzy.

Uses of Pylosak-Kit Combikit Tablet 6's

Pylosak-Kit Combikit Tablet 6's is used in the treatment of hyperacidity, heartburn, stomach ulcer and Zollinger-Ellison syndrome. The detailed uses of Pylosak-Kit Combikit Tablet 6's are as follows:<br/>• Management of Gastroesophageal Reflux Disease (GERD): Pylosak-Kit Combikit Tablet 6's effectively reduces symptoms of GERD, such as heartburn and acid regurgitation, by lowering stomach acid production.<br/>• Healing of Erosive Esophagitis: Pylosak-Kit Combikit Tablet 6's is often prescribed to promote the healing of inflamed oesophageal tissue caused by prolonged exposure to stomach acid.<br/>• Prevention of Peptic Ulcers: Pylosak-Kit Combikit Tablet 6's helps prevent peptic ulcer formation, particularly in individuals undergoing long-term NSAID treatment.<br/>• Eradication of Helicobacter pylori: Pylosak-Kit Combikit Tablet 6's is sometimes included in combination therapy to eliminate Helicobacter pylori infections, which are associated with peptic ulcers.<br/>

Directions for Use

• Take Pylosak-Kit Combikit Tablet 6's with or without food as advised by a doctor. • Follow your doctor’s recommendations on the dosage and timing of this medication to achieve optimal results. • Swallow it as a whole with a glass of water. • Do not crush, chew, or break it.

Medicinal Benefits

Pylosak-Kit Combikit Tablet 6's is a combination medicine that contains Clarithromycin, Esomeprazole, and Amoxicillin. Clarithromycin is an antibiotic that kills bacteria (Helicobacter pylori) causing the infection. Esomeprazole is a proton pump inhibitor (responsible for acid production) and acts by reducing stomach acid production. This effect helps to relieve symptoms of peptic ulcer disease. Amoxicillin is a penicillin antibiotic and bactericidal (kills the bacteria). It works by preventing the formation of the bacterial cell covering (protective cell wall) necessary for their survival. Together, Pylosak-Kit Combikit Tablet 6's is used to treat the infection and peptic ulcer disease.

How Pylosak-Kit Combikit Tablet 6's Works

Pylosak-Kit Combikit Tablet 6's is a combination medicine that contains Clarithromycin, Esomeprazole, and Amoxicillin. Clarithromycin is an antibiotic that kills the bacteria (Helicobacter pylori) causing the infection. Esomeprazole is a proton pump inhibitor and acts by reducing the production of stomach acid. Amoxicillin is a penicillin antibiotic and bactericidal (kills the bacteria). It works by preventing the formation of the bacterial cell covering (protective cell wall) necessary for their survival. Together, Pylosak-Kit Combikit Tablet 6's helps treat and manage peptic ulcer disease effectively.

Storage

Keep this medicine out of the sight and reach of children.

What if I have taken an overdose of Pylosak-Kit Combikit Tablet 6's

Do not take more than the prescribed dose of Pylosak-Kit Combikit Tablet 6's as it may cause an overdose. The symptoms of overdose include stomach pain, vomiting, stomach upset, crystals in the urine (may be seen as cloudy urine) or problems urinating. If you suspect you have taken an overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

Pylosak-Kit Combikit Tablet 6's should not be used in patients with arrhythmias or taking antiarrhythmic agents, as it may lead to prolonged QT intervals, which can be life-threatening. While using Pylosak-Kit Combikit Tablet 6's, if you notice severe or prolonged diarrhoea, vomiting food or blood, black stools, unexplained weight loss, or symptoms of liver disease (jaundice (yellowing of the skin), loss of appetite, dark urine, or itching), stop the medication and consult a doctor immediately. Besides, if you notice skin rashes or lesions, especially on sun-exposed skin, stop the treatment and immediately consult a doctor. Pylosak-Kit Combikit Tablet 6's increases the risk of Clostridium difficile-associated diarrhoea (inflammation of the large intestine due to Clostridium infection). Pylosak-Kit Combikit Tablet 6's may increase the risk of fractures, cause liver impairment, and impair the absorption of vitamin B12 in the body when used for prolonged periods.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Pylosak-Kit Combikit Tablet:
Taking Rifabutin and Pylosak-Kit Combikit Tablet together may increase the blood levels of rifabutin.

How to manage the interaction:
Taking Rifabutin with Pylosak-Kit Combikit Tablet is not recommended as it can possibly result in an interaction, it can be taken if a doctor has advised it. However, consult a doctor immediately If you experience unusual symptoms. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Pylosak-Kit Combikit Tablet:
Combining Pylosak-Kit Combikit Tablet with Pimozide can increase the risk of heart rhythm problems.

How to manage the interaction:
Co-administration of Pylosak-Kit Combikit Tablet and Pimozide can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like irregular heartbeat, chest tightness, blurred vision or nausea, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Pylosak-Kit Combikit Tablet:
When Regorafenib is taken with Pylosak-Kit Combikit Tablet, may alter the blood levels and effects of Regorafenib.

How to manage the interaction:
Co-administration of Pylosak-Kit Combikit Tablet and Regorafenib can lead to an interaction, it can be taken if advised by a doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Pylosak-Kit Combikit Tablet:
Taking Pylosak-Kit Combikit Tablet with Lovastatin can increase the risk of muscle problems.

How to manage the interaction:
Co-administration of Pylosak-Kit Combikit Tablet and Lovastatin can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark-colored urine, and/or yellowing of the skin or eyes, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
ClarithromycinErgotamine
Critical
How does the drug interact with Pylosak-Kit Combikit Tablet:
When Ergotamine is taken with Pylosak-Kit Combikit Tablet, the amount of Ergotamine in the blood can go up.

How to manage the interaction:
Taking Pylosak-Kit Combikit Tablet with Ergotamine can result in an interaction, it should be taken only if a doctor has advised it. However, if you experience abdominal pain, nausea, vomiting, numbness or tingling, muscle pain or weakness, blue or purple discoloration of fingers or toes, pale or cold skin, chest pain or tightness, irregular heartbeat, severe headache, shortness of breath, blurred vision, confusion, and/or slurred speech, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Pylosak-Kit Combikit Tablet:
When Isavuconazole is taken with Pylosak-Kit Combikit Tablet, it can increase the risk of side effects.

How to manage the interaction:
Co-administration of Pylosak-Kit Combikit Tablet and Isavuconazole can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like nausea, vomiting, or diarrhoea, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Pylosak-Kit Combikit Tablet:
Co-administration of Pylosak-Kit Combikit Tablet and Sparfloxacin may result in an increased risk of QT interval prolongation.

How to manage the interaction:
Co-administration of Sertraline and Desvenlafaxine can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Pylosak-Kit Combikit Tablet:
When Nimodipine is taken with Pylosak-Kit Combikit Tablet, it can increase the risk of side effects.

How to manage the interaction:
Co-administration of Pylosak-Kit Combikit Tablet and Nimodipine is not recommended as it can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like irregular heart rhythm, swelling, and low blood pressure, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
Critical
How does the drug interact with Pylosak-Kit Combikit Tablet:
When Naloxegol is taken with Pylosak-Kit Combikit Tablet, the amount of Naloxegol in the blood can go up.

How to manage the interaction:
Co-administration of Pylosak-Kit Combikit Tablet and Naloxegol can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like sweating, tearing, runny nose, chills, diarrhea, abdominal pain, anxiety, insomnia, irritability, restlessness, and yawning, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Pylosak-Kit Combikit Tablet:
Taking Pylosak-Kit Combikit Tablet with Ziprasidone can increase the risk of irregular heart rhythm.

How to manage the interaction:
Co-administration of Pylosak-Kit Combikit Tablet and Ziprasidone can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations, consult a doctor immediately. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Avoid intake of acid or heartburn-triggering foods or drinks like onions, peppermint, chocolate, caffeinated beverages, citrus fruits or juices, tomatoes, and high-fat and spicy foods.
  • Before going to sleep, try to raise your bedhead so that your head and chest are higher than your feet. Do not use piles of pillows; instead, a single raised block is sufficient. This will not allow the stomach acid to backflow through your food pipe.
  • Avoid taking alcohol and smoking cigarettes. Alcohol can raise the level of production of stomach acid, leading to heartburn and acid reflux. On the other hand, nicotine smoking damages the valve (sphincter), preventing stomach acid backflow into the food pipe.
  • Include fibre-rich foods, berries, cherries, leafy green veggies (kale, spinach), and black peppers in your meal. These foods are full of antioxidants, calcium, and vitamin B 12 that can help cope with the medicine's long-term effects. Fermented dairy products like miso, sauerkraut, and kimchi contain probiotics that help prevent excess stomach acid production. Cranberry juice can be beneficial in peptic ulcers and H Pyroli infection.
  • Avoid regular sitting continuously, as it can increase stomach acid production. Try to take a 5-minute break every hour by going for a brisk walk or stretching.

Habit Forming

No

Therapeutic Class

ANTACIDS
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Alcohol

Caution

Consumption of alcohol may increase the risk of side effects such as nausea, vomiting, and diarrhoea, and worsen the health condition.

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Pregnancy

Caution

Pylosak-Kit Combikit Tablet 6's is a pregnancy category C medicine and may cause harmful effects to the fetus if used during pregnancy. However, if clinically needed, your doctor may prescribe Pylosak-Kit Combikit Tablet 6's if the benefits outweigh the risks.

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Breast Feeding

Caution

If you are breastfeeding, consult your doctor before using Pylosak-Kit Combikit Tablet 6's. Your doctor may prescribe this medicine if the benefits outweigh the risks.

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Driving

Caution

Pylosak-Kit Combikit Tablet 6's may cause dizziness or drowsiness in some patients. So, do not drive or operate heavy machinery if you feel dizzy.

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Liver

Caution

In mild to moderate liver impairment, dose adjustments may not be necessary. However, your doctor may have to adjust the dose in patients with severe liver failure.

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Kidney

Caution

In mild to moderate kidney impairment, dose adjustments may not be necessary. However, in patients with severe kidney failure, your doctor may have to adjust the dose.

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Children

Caution

Pylosak-Kit Combikit Tablet 6's should be used with caution in children below 12 years. The dose may have to be adjusted by your doctor.

Have a query?

FAQs

Pylosak-Kit Combikit Tablet 6's is used to treat peptic ulcer disease caused by Helicobacter pylori infection.

Pylosak-Kit Combikit Tablet 6's is a combination medicine that contains Clarithromycin, Esomeprazole, and Amoxicillin. Clarithromycin is an antibiotic that works by killing the bacteria (Helicobacter pylori) that is causing the infection. Esomeprazole is a proton pump inhibitor (responsible for acid production) and reduces stomach acid production. Amoxicillin is a penicillin antibiotic with bactericidal (kills the bacteria) action. Together, Pylosak-Kit Combikit Tablet 6's is used to treat the infection and peptic ulcer disease.

Pylosak-Kit Combikit Tablet 6's contains Esomeprazole, which is an acid suppressant. It can reduce stomach acid production and relieve symptoms such as acid-related heartburn and indigestion.

Pylosak-Kit Combikit Tablet 6's may cause side effects such as headache, diarrhoea, stomach pain, constipation, flatulence, nausea (feeling sick), vomiting (being sick), skin rash, difficulty sleeping, changes in the sense of taste, indigestion, and excessive sweating. These side effects typically resolve on their own without requiring medical attention. However, consult your doctor immediately if these side effects persist or worsen.

It is advisable to avoid acidic foods, such as citrus fruits and tomatoes, as well as spicy foods, caffeinated drinks, chocolate, and alcohol. These foods may increase stomach acid production and worsen health conditions.

It is not advised to take Pylosak-Kit Combikit Tablet 6's for prolonged periods unless prescribed by your doctor. Long-term use of Pylosak-Kit Combikit Tablet 6's may increase the risk of fractures, impair vitamin B12 absorption, and lead to changes in liver function.

Yes, you can take Pylosak-Kit Combikit Tablet 6's with other medications if prescribed by the doctor. To prevent any interactions, inform the doctor if you are taking any other medicines, including herbal products or supplements, while on treatment with Pylosak-Kit Combikit Tablet 6's.

No, Pylosak-Kit Combikit Tablet 6's is not a steroid. It is a combination medication containing a penicillin-type antibiotic (amoxicillin), a macrolide antibiotic (clarithromycin), and a proton pump inhibitor (esomeprazole). It is used to treat peptic ulcer disease caused by Helicobacter pylori infection.

No, Pylosak-Kit Combikit Tablet 6's should not be chewed or crushed. It should be taken as a whole, accompanied by a glass of water.

The Pylosak-Kit Combikit Tablet 6's should be stored in a cool, dry place away from sunlight. Keep it out of sight and reach of children.

Consult the doctor before starting any new medicine while on treatment with Pylosak-Kit Combikit Tablet 6's. Talk to the doctor if you experience severe diarrhoea, sore throat, white mouth, or vaginal itching/discharge. Drink plenty of fluids while taking Pylosak-Kit Combikit Tablet 6's. This medicine may cause dizziness; drive only if you are alert. Consult the doctor if you are pregnant or breastfeeding.

Country of origin

India

Manufacturer/Marketer address

C-110/2, First Floor, Naraina Industrial Area Phase 1, Naraina, New Delhi, Delhi 110028
Other Info - PYL0048

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