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Pylokit Kit is indicated for the eradication of Helicobacter pylori infection associated with peptic ulcer disease. It kills the bacteria by preventing the synthesis of necessary proteins required for vital bacterial functions and damaging their DNA. It also blocks the action of an enzyme called gastric proton pump, which is responsible for acid production, thereby preventing acid-related ulcers.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

CLARITHROMYCIN-250MG+LANSOPRAZOLE-30MG+TINIDAZOLE-500MG

Manufacturer/Marketer :

Cipla Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Pylokit Kit

Pylokit Kit is a combination prescription medicine used to clear Helicobacter pylori (H. pylori) bacterial infections in the stomach. By eradicating these bacteria, it helps heal active peptic ulcers and prevents them from returning. This treatment is highly effective when taken exactly as directed by your healthcare provider.

You must take this medicine consistently every day for the entire duration prescribed by your doctor to ensure successful treatment. It is typically taken on an empty stomach, usually one hour before a meal, to allow the components to absorb properly. Making key lifestyle changes, such as avoiding spicy foods and quitting smoking, can significantly support your stomach's healing process during therapy.

Many patients experience mild side effects while taking this medicine, including a temporary metallic taste in the mouth, nausea, or mild diarrhoea. However, you must contact your doctor immediately if you experience severe symptoms like watery and persistent diarrhoea, yellowing of your skin or eyes, or a rapid, irregular heartbeat.

Talk to your doctor before starting this medicine if you have a history of liver damage, kidney disease, or heart rhythm problems. Do not take this medicine if you are allergic to macrolide antibiotics (such as clarithromycin), nitroimidazole antibiotics (such as tinidazole), or proton pump inhibitors (medicines that reduce stomach acid, such as lansoprazole), or if you are taking certain heart medicines. This medicine is also not suitable for patients with a history of QT prolongation (a heart rhythm disorder that can cause dangerous irregular heartbeats).

This medication can interact with other drugs like blood thinners and cholesterol-lowering statins, making close monitoring necessary. You must completely avoid alcohol during treatment because it can cause severe nausea, headache, and vomiting. If you are pregnant, breastfeeding, or an elderly individual, consult your doctor or pharmacist to discuss safer options.

Uses of Pylokit Kit

Pylokit Kit is used to treat stomach conditions associated with excess stomach acid and bacterial infection. 

  • Helicobacter pylori (H. pylori) Infection: Pylokit Kit helps eliminate the bacteria responsible for stomach inflammation and ulcers.
  • Peptic Ulcer Disease: Pylokit Kit helps reduce stomach acid and treat the underlying infection, allowing stomach and intestinal ulcers to heal and lowering the risk of recurrence.

Key Benefits

Pylokit Kit helps manage stomach conditions by reducing acid production and treating bacterial infections that can contribute to ulcers.

  • Relieves Digestive Symptoms: Helps reduce acid-related discomfort, including burning stomach pain, indigestion, bloating, and nausea.
  • Supports Ulcer Healing: Helps heal the stomach lining and reduces the risk of ulcer recurrence by targeting the underlying infection.
  • Convenient Treatment: The pre-packaged doses make it easier to follow the complete treatment course as prescribed.

Directions for Use

  • Pylokit Kit can be taken before a meal or as advised by your doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication.
  • Swallow Pylokit Kit as a whole with a glass of water.
  • Do not break, chew, or crush it.

How Pylokit Kit Works

Pylokit Kit contains clarithromycin, lansoprazole and tinidazole, which work together to reduce stomach acid and eliminate Helicobacter pylori (H. pylori) infection. Lansoprazole is a proton pump inhibitor that blocks acid-producing pumps in the stomach, reducing acid levels. This creates a healing environment for ulcers and improves the effectiveness of antibiotics. Clarithromycin is a macrolide antibiotic that stops H. pylori bacteria from making essential proteins needed for growth and survival, helping clear the infection. Tinidazole is an antibacterial and antiprotozoal medicine that damages bacterial DNA, helping destroy remaining bacteria and treat the infection.
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Alcohol

Unsafe

Avoid consumption of alcohol while taking Pylokit Kit and for 3 days after discontinuation as it might cause abdominal pain, vomiting, nausea, flushing, and headache.

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Pregnancy

Caution

Consult your doctor if you are pregnant; your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Unsafe

Pylokit Kit contains tinidazole; therefore, breastfeeding should be avoided during treatment and for 72 hours following administration. Consult your doctor if you have any concerns.

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Driving

Caution

Pylokit Kit may cause drowsiness. Do not drive or operate machinery unless you are alert.

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Liver

Caution

Dose adjustment may be needed. Consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed. Consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Unsafe

Pylokit Kit is not recommended for children.

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Heart

Caution

Pylokit Kit should be used with caution in patients with heart problems. Inform your doctor about any heart-related conditions before taking Pylokit Kit.

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Geriatrics

Caution

Pylokit Kit should be given with caution in elderly patients due to an increased risk of side effects. It is important to inform your doctor before using it.

What if I have taken an overdose of Pylokit Kit

If you suspect an overdose, seek immediate medical attention. Symptoms may include severe stomach upset, vomiting, diarrhoea, or extreme dizziness.

Diet & Lifestyle Advise

  • Avoid Alcohol: Do not drink alcohol during treatment and for at least 3 days after your last dose, as it may cause severe reactions such as headaches, flushing, and vomiting.
  • Choose Stomach-Friendly Foods: Avoid spicy, fatty, and highly acidic foods (such as citrus fruits and tomatoes) that may irritate the stomach lining and worsen ulcer pain.
  • Eat Smaller Meals: Have smaller, more frequent meals throughout the day instead of large meals to help prevent excess stomach acid buildup.
  • Stop Smoking: Avoid smoking, as nicotine can slow stomach ulcer healing and reduce the effectiveness of acid-reducing medicines.
  • Manage Stress: Use relaxation techniques such as gentle exercise, deep breathing, or meditation, as high stress levels may increase acid production.

Health Queries

For the past 6 years, I have been experiencing heaviness in my stomach after eating, food coming back into my mouth, gas, a feeling of vomiting, and poor appetite. Despite being 22 years old, my weight has remained around 43 kg during this entire period. What could be the reason?

Bayyarapu Mahesh Kumar

Bayyarapu Mahesh Kumar

M Pharmacy

These symptoms may indicate an underlying digestive disorder that requires medical evaluation. The combination of long-standing digestive complaints and difficulty gaining weight suggests that your body may not be properly processing, digesting, or absorbing food. Since the symptoms have persisted for several years, it is important to consult a gastroenterologist for a thorough assessment. The doctor can determine the cause through appropriate investigations and recommend treatment based on the diagnosis. Identifying the underlying cause is essential to improving both your symptoms and nutritional status.

I have stomach pain, acid reflux, and a feeling of heaviness. I was diagnosed with Helicobacter pylori infection and stomach lining erosion on endoscopy and completed treatment, but the symptoms have returned. What are the permanent treatment options?

G.santoshini Reddy

G.santoshini Reddy

M Pharmacy (Pharmaceutics)

Since your symptoms have returned after treatment for Helicobacter pylori, you should first confirm if the infection is still present with a follow-up test. If positive, a different antibiotic combination may be needed. If negative, the problem is likely ongoing acidity or gastritis, which can be managed with acid-reducing medicines for some time. Long-term relief depends on lifestyle changes; avoid spicy and oily foods, reduce tea/coffee, eat small, regular meals, and avoid lying down after eating. Maintaining a healthy routine often plays a key role in permanent relief. If symptoms keep coming back despite treatment, your doctor may reassess with repeat tests or an endoscopy to rule out other causes. With proper follow-up, the condition can usually be well controlled and kept from recurring.

I have completed the full 7-day course of the Pylokit Kit, but I haven’t noticed any improvement. How does it work? When can I expect results?

Bayyarapu Mahesh Kumar

Bayyarapu Mahesh Kumar

M Pharmacy

The Pylokit Kit is designed to treat Helicobacter pylori (H. pylori) infection, which can cause stomach ulcers and gastritis. It usually contains a combination of other medications to eliminate the bacteria and promote healing. It’s important to complete the full course as prescribed, but sometimes symptoms may not improve immediately after finishing treatment. Healing can take time, and some discomfort might persist for a few weeks. If you don’t see any improvement or your symptoms worsen, it’s essential to consult your doctor. They may recommend further tests or a different treatment plan to ensure the infection is fully cleared.

I’m 55 years old. How many days should I take this kit (Pylokit Kit)?

Bayyarapu Mahesh Kumar

Bayyarapu Mahesh Kumar

M Pharmacy

The usual duration for taking the Pylokit Kit is 7 to 14 days, but the exact number of days depends on your doctor’s advice and your medical condition. It is used to treat H. pylori infections in the stomach. Always follow your doctor’s instructions carefully and complete the full course even if you start feeling better, to ensure the infection is fully cleared. Do not change the dose or stop early without consulting your doctor. Let your doctor know if you experience any side effects while using this kit.
health query

Have a query?

How Soon It Starts Working

The time required for Pylokit Kit to start to work: The time required for Pylokit Kit to show its action is unknown. The time for which the effects of Pylokit Kit last: The duration of action for Pylokit Kit is clinically unknown.

What if you forget to take Pylokit Kit

If you miss a dose, take it as soon as you remember. If it is almost time for your next scheduled dose, skip the missed dose and resume your regular dosing schedule. Do not take a double dose to make up for a missed one.

Storage

•Store Pylokit Kit at room temperature, between 15°C and 30°C (59°F to 86°F).•Keep the medicine in its original blister pack to protect the tablets and capsules from light and moisture.

Drug Warnings

  • Complete the Full Course: Take the entire treatment exactly as prescribed, even if symptoms improve, to prevent the infection from returning or becoming harder to treat.
  • Check the Packaging: Inspect the blister foil before use. Do not take any tablet or capsule if the packaging is broken, torn, or damaged.
  • Avoid Driving if Affected: Do not drive or operate machinery if you experience dizziness, confusion, or lightheadedness after taking this medicine.
  • Report Severe Diarrhoea: Contact your doctor immediately if you develop severe, watery diarrhoea during treatment or even several weeks after completing the course.
  • Inform Your Doctor: Provide a complete list of all medicines you are taking before starting treatment, as this combination may interact with other drugs.

Drug-Drug Interactions

verifiedApollotooltip

Pylokit Kit may interact with other medicines. Tell your doctor about all medicines you are taking before starting treatment. 

  • Heart Rhythm Medicines: May increase the risk of serious irregular heart rhythms when used with medicines such as pimozide, cisapride, astemizole, or terfenadine.
  • Blood Thinners (such as warfarin): May increase the risk of bleeding when taken together.
  • Cholesterol-Lowering Medicines (statins): May increase statin levels in the blood, raising the risk of side effects.
  • Seizure or Gout Medicines: May interact with medicines such as phenytoin or colchicine, increasing the risk of harmful effects.
No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

verifiedApollotooltip

Pylokit Kit may interact with certain foods or drinks, which can affect your safety during treatment.

  • Alcohol: Avoid alcohol during treatment, as it may cause a disulfiram-like reaction with symptoms such as severe headache, flushing, rapid heartbeat, nausea, and vomiting.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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FAQs

Pylokit Kit is indicated for the eradication of Helicobacter pylori associated with peptic ulcer disease.
Pylokit Kit contains Clarithromycin, Lansoprazole, and Tinidazole. Clarithromycin and tinidazole kill the bacteria by interfering with their functioning. Lansoprazole works by blocking the action of an enzyme called gastric proton pump, which is responsible for the production of acid, thereby prevents acid-related ulcers. Together, Pylokit Kit helps treat ulcers.
Diarrhoea might be a side-effect of Pylokit Kit. Drink enough fluids and eat non-spicy food if you experience diarrhoea. Consult your doctor if you have watery stools and stomach pain.
Pylokit Kit contains lansoprazole which might increase the risk of bone fracture in the hip, spine or wrist. This mainly occurs in people taking higher doses/multiple doses of Pylokit Kit for longer durations. Inform your doctor before taking Pylokit Kit if you have osteoporosis.
To treat your condition effectually, continue taking Pylokit Kit for as long as your doctor has advised. Do not be reluctant to speak with your doctor if you experience any difficulty whilst taking Pylokit Kit.
Avoid taking Pylokit Kit if you have a history of heart conditions such as ventricular cardiac arrhythmia or QT prolongation. Talk to your doctor if you have any concerns.
No, you must avoid alcohol completely while taking Pylokit Kit and for at least 3 days after finishing your last dose. Combining alcohol with this medicine can cause a severe reaction, including throbbing headaches, rapid heart rate, flushing, nausea, and vomiting. Talk to your doctor or pharmacist if you have concerns.
A temporary metallic taste is a very common and harmless side effect of the antibiotic ingredients in Pylokit Kit. You can manage this by maintaining good oral hygiene, chewing sugar-free gum, or sucking on hard candies. The taste will go away once your treatment is complete. Talk to your doctor or pharmacist if it becomes too bothersome.
Pylokit Kit is generally not recommended during pregnancy or breastfeeding unless your doctor decides the benefits clearly outweigh the potential risks. Some active components can pass into breast milk or affect the developing baby. Talk to your doctor or pharmacist to discuss your specific situation.
It is highly recommended to take the components of Pylokit Kit on an empty stomach, usually one hour before a meal. This helps the acid-reducing capsule absorb properly and work effectively. However, if you experience severe stomach upset, talk to your doctor or pharmacist for specific advice.
Yes, Pylokit Kit can interact with several common medications, including blood thinners, statins, and heart medicines, potentially causing serious side effects. Always give your doctor or pharmacist a complete list of all prescription medicines, over-the-counter drugs, and herbal supplements you are taking before starting this therapy.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013
Other Info - PYL0003

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