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compositionComposition:CLOBETASOL PROPIONATE-0.05%W/W
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Prescription Medicine
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Psovate 0.05% Cream 30 gm is a corticosteroid medicine which is used in the treatment of autoimmune skin disorders like eczema, psoriasis, lichen planus, and discoid lupus erythematosus. This medicine contains clobetasol which works by inhibiting the production of certain chemical messengers in the body that cause inflammation and thus reduces swelling, redness, and itching.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
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More about the Product

Composition :

CLOBETASOL PROPIONATE-0.05%W/W

Manufacturer/Marketer :

Newrish Pharmaceuticals

Consume Type :

Topical

Expires on or after :

Dec-28

Return Policy :

Not Returnable

About Psovate 0.05% Cream 30 gm

Psovate 0.05% Cream 30 gm is a highly potent topical medicine used to treat severe inflammatory skin conditions such as psoriasis, eczema, and dermatitis. It works by reducing the redness, swelling, and intense itching associated with these stubborn skin issues. This medication is typically prescribed when milder treatments have not provided sufficient relief.

You should apply Psovate 0.05% Cream 30 gm consistently and exactly as directed by your doctor, usually once or twice daily. Because this is a cream or ointment, you apply it directly to the affected skin, meaning it does not need to be taken with food. Making simple lifestyle adjustments, such as avoiding harsh soaps and keeping your skin well-moisturized, can significantly support your treatment progress.

While using Psovate 0.05% Cream 30 gm, you may experience mild local reactions like a slight burning sensation or temporary irritation where the medicine was applied. However, if you notice severe skin thinning, skin color changes, or signs of a new skin infection, you should contact your doctor right away.

Before starting this medicine, tell your doctor if you have liver damage or problems with your adrenal glands. Do not use this medicine if you have an untreated skin infection, such as herpes, chickenpox, or a fungal infection, in the area you need to treat.

It is important to discuss all other topical products, cosmetics, or medicines you are using with your healthcare provider to prevent any unwanted interactions. Pregnant women, breastfeeding mothers, or elderly individuals should consult their doctor before using Psovate 0.05% Cream 30 gm to ensure it is safe for their specific situation.

Uses of Psovate 0.05% Cream 30 gm

Psovate 0.05% Cream 30 gm helps reduce inflammation, relieve itching, and improve skin healing. Your doctor may recommend it for the following conditions:

  • Psoriasis: Psovate 0.05% Cream 30 gm helps reduce the thick, scaly plaques, redness, and itching associated with moderate to severe plaque psoriasis.
  • Severe Eczema: It provides rapid relief from intense itching, redness, and inflammation caused by severe atopic dermatitis.
  • Lichen Planus: Psovate 0.05% Cream 30 gm calms the swelling, irritation, and purple, itchy bumps characteristic of this inflammatory skin condition.
  • Lupus Erythematosus: It helps manage localized discoid lupus skin lesions by reducing inflammation and preventing further tissue damage.

Key Benefits

Psovate 0.05% Cream 30 gm helps relieve inflammation, itching, and redness associated with severe skin conditions. Key benefits include:

  • Relieves itching and burning: Helps provide fast relief from intense itching and skin discomfort.
  • Reduces redness and swelling: Helps improve the appearance of inflamed skin by reducing redness and swelling.
  • Treats severe skin flare-ups: Helps control stubborn skin conditions that do not respond well to milder treatments.
  • Works directly on affected skin: Delivers targeted relief at the application site while minimising exposure to the rest of the body.
Side effects of Psovate 0.05% Cream 30 gm
  • Avoid extreme heat or cold, like hot showers or cold winds, to prevent worsening skin discomfort.
  • Cool compresses: To reduce itch, redness, and swelling.
  • Avoid irritants like harsh chemicals or allergens to prevent worsening skin discomfort.
  • If you have severe itching, burning, or blistering seek medical attention.
  • Keep your skin clean by gently washing your face two times daily and after sweating. Choose a mild and non-abrasive cleanser.
  • Use gentle alcohol-free skin care products. Avoid products that might irritate your skin such as exfoliants, astringents and toners.
  • Acne may also occur due to oil in the hair. Thus, if you have oily hair, shampoo more frequently than you do now and keep your hair away from face.
  • Keep your hands off your face as touching face throughout the day might worsen acne. Also, do not pick, squeeze or pop acne as it will prolong the healing process and increase the risk of dark spots and scarring.
  • Avoid tanning by applying a broad spectrum sunscreen and wearing sun-protective clothing when outdoors.
  • Mild hair follicle inflammation often heals on its own without needing treatment.
  • You can apply a warm saltwater or vinegar solution to the affected area with a washcloth, or use over-the-counter antibiotics, oatmeal lotion, or hydrocortisone cream for relief.
  • Avoid making the affected area worse by not shaving, scratching, or wearing tight clothes.
  • Apply a warm compress to the area 3-4 times a day for 15-20 minutes to help speed up healing.
  • Do not scratch, squeeze, or pop any bumps, as this may lead to infection or other problems.
  • If self-care methods fail, consult a doctor for further treatment and advice.
  • Shield your skin from the sun by using sunscreen, seeking shade, and wearing protective clothing.
  • Please don't smoke, as it damages the skin and reduces blood flow.
  • Treat your skin gently by limiting bath time, using mild cleansers, and shaving carefully.
  • Eat a healthy diet of fruits, vegetables, whole grains, and lean proteins.
  • Stay hydrated by drinking plenty of water.
  • Manage stress through sleep, exercise, meditation, and enjoyable activities.
  • Additionally, use moisturizers to coat your skin with a protective barrier, and consider wearing sun-protective clothing.
  • Apply moisturizer immediately after showering or bathing.
  • Use a moisturizer containing lanolin, petroleum jelly, glycerine, hyaluronic acid or jojoba oil.
  • Do not use hot water for bathing. Instead use warm water and limit showers and bath to 5 to 10 minutes.
  • Apply a sunscreen with SPF-30 or higher.
  • Avoid harsh soaps, detergents and perfumes.
  • Do not scratch or rub the skin.
  • Drink adequate water to prevent dehydration.
  • Wear pants, full sleeves and a wide-brimmed hat while going out in the sun.

Directions for Use

  • Advised to apply Psovate 0.05% Cream 30 gm twice daily; however, follow your doctor's recommendation regarding the dosage and duration.
  • Take a small amount of Psovate 0.05% Cream 30 gm on the fingertip and apply as a thin layer on the clean and dry affected area as prescribed by your doctor.
  • It is only for external use.
  • Avoid Psovate 0.05% Cream 30 gm contact with the nose, mouth, or eyes. In case of accidental contact with these areas, rinse with water thoroughly.
  • Wash your hands before and after using Psovate 0.05% Cream 30 gm if your hands are not the affected area to prevent the spread of infection.

How Psovate 0.05% Cream 30 gm Works

Psovate 0.05% Cream 30 gm contains clobetasol propionate, a very high-potency topical corticosteroid that works by reducing inflammation in the skin. When applied to the affected area, it is absorbed into the skin cells to target the underlying causes of inflammation. Psovate 0.05% Cream 30 gm works by blocking the release of specific natural substances in the body that trigger swelling, redness, and itching. By calming this overactive immune response in the skin, it helps relieve symptoms and allows the skin barrier to heal and return to its normal state.
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Alcohol

Safe if prescribed

Psovate 0.05% Cream 30 gm may not affect by alcohol consumption.

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Pregnancy

Caution

Psovate 0.05% Cream 30 gm should be used in pregnant women only if clinically needed, and the benefits outweigh the risks. If you are pregnant, please consult your doctor before using Psovate 0.05% Cream 30 gm.

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Breast Feeding

Caution

Psovate 0.05% Cream 30 gm should be used in breastfeeding mothers only if the benefits outweigh the risks. If you are breastfeeding, consult your doctor before using Psovate 0.05% Cream 30 gm. Take care that the medicine should not come in contact with your infant.

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Driving

Safe if prescribed

Psovate 0.05% Cream 30 gm does not impact your ability to drive or operate machinery or tools.

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Liver

Safe if prescribed

No relevant interactions were found or established. Psovate 0.05% Cream 30 gm can be used in people with liver disease if prescribed by a healthcare professional.

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Kidney

Safe if prescribed

No relevant interactions were found or established. Psovate 0.05% Cream 30 gm can be used in people with kidney disease if prescribed by a healthcare professional.

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Children

Caution

Psovate 0.05% Cream 30 gm use in children is restricted and should be done only with the approval of a child specialist.

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Heart

Consult your doctor

Inform your doctor if you have heart disease before using Psovate 0.05% Cream 30 gm. Your doctor will prescribe only if the benefits outweigh the risks.

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Geriatrics

Consult your doctor

Psovate 0.05% Cream 30 gm should be used in the elderly only when prescribed by a doctor. If you have any concerns about using Psovate 0.05% Cream 30 gm for geriatrics, please consult a doctor.

What if I have taken an overdose of Psovate 0.05% Cream 30 gm

Using too much Psovate 0.05% Cream 30 gm or applying it over very large areas for a long time can lead to serious side effects, including hormonal imbalances. If you suspect an overdose, or if someone accidentally swallows the medicine, seek medical attention immediately.

Diet & Lifestyle Advise

  • Moisturise regularly: Use a gentle, fragrance-free moisturiser every day to help maintain your skin's natural moisture barrier.
  • Avoid hot water: Take lukewarm showers or baths, as hot water can worsen skin dryness and itching.
  • Wear soft clothing: Choose loose-fitting, cotton clothing to help reduce skin irritation caused by friction.
  • Avoid skin triggers: Stay away from harsh detergents, synthetic fabrics, or foods that seem to trigger your skin flare-ups.
health query

Have a query?

How Soon It Starts Working

The time required for Psovate 0.05% Cream 30 gm to start to work: The time required for Psovate 0.05% Cream 30 gm to show its action is unknown. The time for which the effects of Psovate 0.05% Cream 30 gm last: The duration of action for Psovate 0.05% Cream 30 gm is unknown.

What if you forget to take Psovate 0.05% Cream 30 gm

If you miss an application, apply it as soon as you remember. If it is almost time for your next scheduled application, skip the missed one and continue with your regular routine. Do not apply extra medicine to make up for a missed dose.

Storage

•Store Psovate 0.05% Cream 30 gm at room temperature, ideally between 68°F and 77°F (20°C and 25°C).•Keep the tube tightly closed when not in use.

Drug Warnings

  • Avoid sensitive areas: Do not apply Psovate 0.05% Cream 30 gm to your face, underarms, or groin unless your doctor specifically instructs you to do so.
  • Use for the recommended duration: Do not use Psovate 0.05% Cream 30 gm continuously for more than 2 weeks unless advised by your doctor.
  • Do not apply to damaged skin: Avoid using Psovate 0.05% Cream 30 gm on open wounds, cuts, or infected skin.
  • Use with caution in children: Do not use Psovate 0.05% Cream 30 gm in children unless recommended by a paediatrician.
  • Do not cover the treated area: Avoid wrapping or bandaging the treated skin, especially with plastic dressings, unless instructed by your doctor.
  • Do not stop prolonged treatment suddenly: If you have been using Psovate 0.05% Cream 30 gm for several weeks, stopping it abruptly may cause your skin condition to flare up again (rebound flare) or, rarely, lead to topical steroid withdrawal symptoms. Follow your doctor's instructions when reducing or stopping treatment.

Drug-Drug Interactions

verifiedApollotooltip
  • Other topical steroids: Tell your doctor if you are using other topical steroid products, as combining them may increase the risk of systemic side effects and skin thinning.
No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

verifiedApollotooltip

No clinically significant food interactions are known with Psovate 0.05% Cream 30 gm when used as directed.

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[CORTICOSTEROIDS]

FAQs

Psovate 0.05% Cream 30 gm belongs to a class of topical corticosteroid medications. It is used for the treatment of autoimmune skin disorders such as psoriasis, discoid lupus erythematosus (red, coin-shaped scales or crusts on the scalp, cheeks, and ears), and eczema.
Psovate 0.05% Cream 30 gm can bleach and lighten skin. However, using Psovate 0.05% Cream 30 gm for skin lightening is not clinically established. So, it should be used when prescribed by a doctor.
Psovate 0.05% Cream 30 gm is not recommended for the treatment of burns. This medicine should not also use on broken skin or open wounds.
In rare cases, Psovate 0.05% Cream 30 gm may stimulate hair growth. However, it should be used when advised by a doctor.
Using too much of the Psovate 0.05% Cream 30 gm or using it for a long time may increase your risk of having adrenal gland problems.
Yes, you are eligible to take vaccines, but tell the doctor or nurse that you're using Clobetasol Propionate so they can give the vaccine in an untreated area of the skin.
Prolonged use of Psovate 0.05% Cream 30 gm may result in skin thinning, leading to stretch marks.
No, Psovate 0.05% Cream 30 gm is not an antifungal medication. It contains clobetasol propionate, which is a topical corticosteroid used to treat inflammatory skin conditions like psoriasis, eczema, and dermatitis.
Take a small amount of Psovate 0.05% Cream 30 gm on the fingertip and apply a thin layer on the clean and dry affected area as prescribed by your doctor. It is only for external use. Avoid cream/lotion contact with the nose, mouth, or eyes. In case of accidental contact with these areas, rinse with water thoroughly. Wash your hands before and after using Psovate 0.05% Cream 30 gm if your hands are not the affected area to prevent the spread of infection.
No, do not stop using Psovate 0.05% Cream 30 gm abruptly and complete the full course of treatment as prescribed by your doctor. Discontinuing the treatment too soon can lead to a recurrence of the condition.
Avoid direct contact of Psovate 0.05% Cream 30 gm with your nose, mouth, or eyes. In case of accidental contact with these areas, rinse with water thoroughly. Avoid using more than the recommended dose. Avoid covering the treated region with a bandage or dressing as this will increase the Psovate 0.05% Cream 30 gm absorption and raise the possibility of adverse effects. Never share your medicine with anyone else, even if they seem to have the same disease.
No, using Psovate 0.05% Cream 30 gm more than prescribed will not make it more effective and can cause harm. Overuse of corticosteroids like clobetasol can lead to undesirable effects such as skin thinning, irritation, and systemic absorption leading to hormonal imbalances. Therefore, it's important to use Psovate 0.05% Cream 30 gm exactly as your doctor has prescribed, to ensure safe and effective treatment.
Store Psovate 0.05% Cream 30 gm at room temperature, in a cool and dry place away from sunlight and moisture. Tightly close the cap of tube after each usage to prevent contamination. Keep it out of reach of children.
The common side effects of Psovate 0.05% Cream 30 gm are burning or stinging sensation, pain, irritation or itching, skin thinning may cause stretch marks and blood vessels under the surface of your skin may become more noticeable. If any of these side effects persist or worsen, please consult your doctor.
You should not use Psovate 0.05% Cream 30 gm on your face unless your doctor specifically tells you to do so. The skin on your face is very thin and sensitive, making it more vulnerable to side effects like skin thinning, redness, and acne. Talk to your doctor for a safer alternative.
You must consult your doctor before using this medicine while breastfeeding. If your doctor advises it is safe, make sure not to apply the cream to your chest area to prevent the baby from accidentally swallowing or contacting the medicine. Talk to your doctor for personalized advice.
Skin thinning is a recognized side effect of prolonged use of strong topical steroids. If you notice your skin becoming thin, easily bruised, or showing stretch marks, stop using the medication and talk to your doctor right away to adjust your treatment plan.
Children are much more sensitive to the side effects of strong topical steroids because of their thinner skin and higher body surface area. You should never use Psovate 0.05% Cream 30 gm on a child unless a pediatrician has explicitly prescribed it. Talk to your doctor or pharmacist.
Yes, if used over large areas of the body, for a very long time, or under tight dressings, enough medicine can be absorbed into your bloodstream to cause hormonal changes. This can lead to conditions like adrenal suppression, which may cause weight gain and fatigue. Talk to your doctor if you experience these symptoms.

Disclaimer

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Reference

  1. National Health Service (NHS). Clobetasol - NHS Medicines Reference Guide. London, UK: NHS; 2025. [Accessed on 02 Jun. 2026]Check here
  2. Drugs.com Clinical Review Team. Clobetasol Topical Drug Interactions Reference. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026]Check here
  3. Electronic Medicines Compendium (EMC). Pil.939 Patient Information Leaflet (PIL). Cheshire, UK: Datapharm; 2025. [Accessed on 02 Jun. 2026]Check here
  4. Bethesda (MD). Clobetasol. National Institute of Health. NLM. National Centre for Biotechnology Information. PubChem Compound Summary. 2004. [Accessed on 17th June 2022]Check here
  5. Bethesda (MD). Miconazole. National Institute of Health. NLM. National Centre for Biotechnology Information. PubChem Compound Summary. 2004. [Accessed on 17th June 2022]Check here
  6. Bethesda (MD). Neomycin. National Institute of Health. NLM. National Centre for Biotechnology Information. PubChem Compound Summary. 2004. [Accessed on 17th June 2022]Check here
  7. CDSCO. [Accessed on 02 Jun. 2026]Check here

Country of origin

India

Manufacturer/Marketer address

1, Kaliappan St, Jeeva Nagar, Kuppakonam Pudur, K K Pudur, Coimbatore, Tamil Nadu 641038
Other Info - PSO0081

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