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Provil Plus Capsule is used to treat migraine. Migraine is a medical condition that involves severe throbbing pain or a pulsing sensation on one side of the head. Severe and recurrent headaches are one of the characteristic symptoms of migraine. Its symptoms include nausea, vomiting, difficulty speaking, numbness or tingling, and sensitivity to light and sound.
Provil Plus Capsule consists of 'Propranolol' (beta-blocker) and 'Flunarizine' (calcium channel blocker). Propranolol has anxiolytic (anxiety-reducing), anti-arrhythmic (treats abnormal heart rhythms), and antihypertensive (reduces blood pressure) properties. Propranolol works by reducing cerebral (brain) blood flow by directly acting on the brain's blood vessels. It also inhibits the cortical spreading of depression and electrical activity in the brain that causes pain and inflammation. It effectively treats and reduces the severity and frequency of migraine headaches. Flunarizine belongs to the class of calcium channel blockers. It improves blood flow and dilates blood vessels in the brain, thereby preventing headaches caused by migraine. It is also used to treat vertigo (spinning sensation).
Your doctor will decide the dose and duration based on the severity of your pain. Common side effects of Provil Plus Capsule include dry weight gain, slow heart rate, tiredness, depression, drowsiness, abnormal dreams, and cold extremities (hands and feet). These side effects are not familiar to everyone and vary individually. If you notice any side effects that are not manageable, please consult your doctor.
Let your doctor know if you use any prescription and non-prescription medications you are taking, including other vitamins, before starting Provil Plus Capsule . Provil Plus Capsule may cause weight gain in some cases, so avoid eating junk and eat a healthy, balanced diet, including home-cooked food. Consult your doctor before taking Provil Plus Capsule if you are pregnant, planning for pregnancy or breastfeeding. Avoid consuming alcohol along with Provil Plus Capsule as it could lead to increased drowsiness.
Provil Plus Capsule is used in the treatment of migraine. The detailed uses of Provil Plus Capsule are as follows:
Provil Plus Capsule is used to treat migraine. It consists of 'Propranolol' and 'Flunarizine'. Propranolol is a beta-blocker and has anxiolytic (anxiety-reducing), anti-arrhythmic, and antihypertensive properties. It works by lowering cerebral (brain) blood flow and inhibits cortical spreading depression, as well as electrical activity in the brain that causes pain and inflammation. It reduces the severity and frequency of migraine headaches. Flunarizine is a channel blocker that improves blood flow and dilates blood vessels in the brain, thereby preventing headaches caused by migraine.
Unsafe
You are recommended to avoid alcohol consumption while taking Provil Plus Capsule . Alcohol intake, along with Provil Plus Capsule , may cause increased dizziness and drowsiness.
Caution
Please consult your doctor if you are pregnant or planning to conceive before using Provil Plus Capsule .
Caution
Please consult your doctor before taking Provil Plus Capsule if you are a lactating mother.
Caution
Provil Plus Capsule may make you feel drowsy. Do not drive or operate machinery if you experience drowsiness.
Caution
Therapy with propranolol should be administered cautiously in patients with liver disease. Please consult your doctor if you have a history of liver impairment/liver disease.
Caution
Plasma clearance of Propranolol in Provil Plus Capsule is reduced in patients with renal failure. Please consult your doctor if you have a history of kidney impairment/kidney disease.
Safe if prescribed
Provil Plus Capsule is safe to use for children below 12 years of age when prescribed by the doctor.
Caution
Provil Plus Capsule should be taken with extreme caution in patients with heart disease. Please consult your physician.
Caution
Provil Plus Capsule can be given in elderly patients with caution due to increased risk of adverse effects.
Have a query?
Inform your doctor if you have any history of liver or kidney diseases, breathing problems (asthma, bronchitis, emphysema), diabetes, heart failure, heart rhythm problems (sinus bradycardia, Wolff-Parkinson-White syndrome, atrioventricular block), overactive thyroid, blood circulation problems (Raynaud's disease), adrenal gland tumour (pheochromocytoma), depression, metabolic acidosis (excess acid in the blood), and myasthenia gravis (muscle weakness) before starting Provil Plus Capsule . Please consult your doctor if you are pregnant and planning to conceive if the doctor advised you Provil Plus Capsule . Avoid consuming alcohol along with Provil Plus Capsule as it could lead to increased dizziness and drowsiness.
Drug-Drug Interaction: Provil Plus Capsule may interact with mood disorder medicines (alprazolam, quetiapine, aripiprazole), drugs treating sleeping problems (zolpidem), respiratory drugs (diphenhydramine), antidepressants (sertraline, duloxetine, fluoxetine), and fits medicine (carbamazepine, phenytoin).
Drug-Food Interaction: Alcohol may cause dizziness and drowsiness when taken with Provil Plus Capsule .
Drug-Disease Interaction: Before using Provil Plus Capsule , let your doctor know if you have any liver, kidney or heart diseases, asthma, depression, muscle disorders, metabolic acidosis, diabetes, and alcohol dependency.
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Provil Plus Capsule belongs to the class of anti-migraine drugs used to treat migraine.
Provil Plus Capsule is a combination of two drugs: Propranolol and Flunarizine. Provil Plus Capsule treats migraine by reducing the blood flow to the brain, and inhibits cortical spreading depression, electrical activity in the brain that causes pain and inflammation.
Provil Plus Capsule may sometimes cause weight gain during its prolonged use. It is always advised to maintain a well-balanced, healthy diet and exercise regularly.
Provil Plus Capsule does not work for a sudden migraine attack. It is helpful in only preventing new episodes of migraine headaches. Please let your doctor know if you have sudden attacks to be prescribed other suitable medications.
Provil Plus Capsule is contraindicated in asthma, slow heart rate, abnormal heart rhythms, heart conditions like AV (Atrioventricular) block or sick sinus syndrome, depression, and Parkinson's disease. Please consult your doctor before starting Provil Plus Capsule if you have a medical history.
Your doctor will prescribe Provil Plus Capsule to prevent any new episodes of migraine. Please do not stop taking this medicine unless advised by your doctor since it may lead to recurrent episodes of migraine. Provil Plus Capsule also contains Propranolol, and its sudden withdrawal may cause sweating, shaking, irregular heartbeat, and worsening of underlying angina or heart attack. Hence, do not stop using Provil Plus Capsule unless advised by your doctor.
Provil Plus Capsule may cause sleepiness in some individuals as a potential side effect. If this occurs, exercise caution and avoid activities that require mental alertness, such as driving or operating heavy machinery.
Store Provil Plus Capsule at room temperature in a cool and dry place, away from sunlight and moisture. Keep out of reach of children.
The common side effects of Provil Plus Capsule are weight gain, slow heart rate, tiredness, depression, drowsiness, abnormal dreams, and cold extremities (hands and feet). Please consult your doctor if any of these side effects persist or worsen.
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