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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Promigra F 20mg/10mg Tablet is used to treat migraine. It contains Propranolol and Flunarizine which improves blood flow and dilates blood vessels in the brain, thereby preventing headaches caused due to migraine. It effectively treats and reduces the severity and frequency of migraine headaches. Also, it is also used to treat vertigo (spinning sensation). It may cause common side effects such as dry weight gain, slow heart rate, tiredness, depression, drowsiness, abnormal dreams, and cold extremities (hands and feet). Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Consume Type :

ORAL

Return Policy :

Not Returnable

About Promigra F 20mg/10mg Tablet

Promigra F 20mg/10mg Tablet is used to treat migraine. Migraine is a medical condition that involves severe throbbing pain or a pulsing sensation on one side of the head. Severe and recurrent headaches are one of the characteristic symptoms of migraine. Its symptoms include nausea, vomiting, difficulty speaking, numbness or tingling, and sensitivity to light and sound.

Promigra F 20mg/10mg Tablet consists of 'Propranolol' (beta-blocker) and 'Flunarizine' (calcium channel blocker). Propranolol has anxiolytic (anxiety-reducing), anti-arrhythmic (treats abnormal heart rhythms), and antihypertensive (reduces blood pressure) properties. Propranolol works by reducing cerebral (brain) blood flow by directly acting on the brain's blood vessels. It also inhibits the cortical spreading of depression and electrical activity in the brain that causes pain and inflammation. It effectively treats and reduces the severity and frequency of migraine headaches. Flunarizine belongs to the class of calcium channel blockers. It improves blood flow and dilates blood vessels in the brain, thereby preventing headaches caused by migraine. It is also used to treat vertigo (spinning sensation).

Your doctor will decide the dose and duration based on the severity of your pain. Common side effects of Promigra F 20mg/10mg Tablet include dry weight gain, slow heart rate, tiredness, depression, drowsiness, abnormal dreams, and cold extremities (hands and feet). These side effects are not familiar to everyone and vary individually. If you notice any side effects that are not manageable, please consult your doctor.

Let your doctor know if you use any prescription and non-prescription medications you are taking, including other vitamins, before starting Promigra F 20mg/10mg Tablet. Promigra F 20mg/10mg Tablet may cause weight gain in some cases, so avoid eating junk and eat a healthy, balanced diet, including home-cooked food. Consult your doctor before taking Promigra F 20mg/10mg Tablet if you are pregnant, planning for pregnancy or breastfeeding. Avoid consuming alcohol along with Promigra F 20mg/10mg Tablet as it could lead to increased drowsiness.

Uses of Promigra F 20mg/10mg Tablet

Treatment of Migraine.

Directions for Use

• Take Promigra F 20mg/10mg Tablet with or without food or as advised by a doctor.• Follow your doctor's instructions on the dosage and timing of this medication, to ensure the safety.• Swallow the medicine as a whole with glass of water.• Do not crush, break, or chew it.

Medicinal Benefits

Promigra F 20mg/10mg Tablet is used to treat migraine. It consists of 'Propranolol' and 'Flunarizine'. Propranolol is a beta-blocker and has anxiolytic (anxiety-reducing), anti-arrhythmic, and antihypertensive properties. It works by lowering cerebral (brain) blood flow and inhibits cortical spreading depression, as well as electrical activity in the brain that causes pain and inflammation. It reduces the severity and frequency of migraine headaches. Flunarizine is a channel blocker that improves blood flow and dilates blood vessels in the brain, thereby preventing headaches caused by migraine. 

How Promigra F 20mg/10mg Tablet Works

Promigra F 20mg/10mg Tablet consists of 'Propranolol' (beta-blocker) and 'Flunarizine' (calcium channel blocker). Propranolol has anxiolytic (anxiety-reducing), anti-arrhythmic (treats abnormal heart rhythms), and antihypertensive (reduces blood pressure) properties. Propranolol works by reducing cerebral (brain) blood flow by directly acting on the brain's blood vessels. It also inhibits the cortical spreading of depression and electrical activity in the brain that causes pain and inflammation. It effectively treats and reduces the severity and frequency of migraine headaches. Flunarizine belongs to the class of calcium channel blockers. It improves blood flow and dilates blood vessels in the brain, thereby preventing headaches caused by migraine.

Storage

Keep Promigra F 20mg/10mg Tablet out of sight and reach of children.

What if I have taken an overdose of Promigra F 20mg/10mg Tablet

Do not take more than the prescribed dose of Promigra F 20mg/10mg Tablet as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

Inform your doctor if you have any history of liver or kidney diseases, breathing problems (asthma, bronchitis, emphysema), diabetes, heart failure, heart rhythm problems (sinus bradycardia, Wolff-Parkinson-White syndrome, atrioventricular block), overactive thyroid, blood circulation problems (Raynaud's disease), adrenal gland tumour (pheochromocytoma), depression, metabolic acidosis (excess acid in the blood), and myasthenia gravis (muscle weakness) before starting Promigra F 20mg/10mg Tablet. Please consult your doctor if you are pregnant and planning to conceive if the doctor advised you Promigra F 20mg/10mg Tablet. Avoid consuming alcohol along with Promigra F 20mg/10mg Tablet as it could lead to increased dizziness and drowsiness.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Promigra F 20mg/10mg Tablet:
Coadministration of thioridazine with Promigra F 20mg/10mg Tablet may increase the blood levels of thioridazine and cause an irregular heart rhythm that may be serious.

How to manage the interaction:
Although there is an interaction between Promigra F 20mg/10mg Tablet and thioridazine, they can be taken together if prescribed by a doctor. However, if you experience sudden dizziness, lightheadedness, fainting, and shortness of breath contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Promigra F 20mg/10mg Tablet:
Using fingolimod with Promigra F 20mg/10mg Tablet can cause an excessive lowering of heart rate and can lead to other heart problems.

How to manage the interaction:
Although taking Promigra F 20mg/10mg Tablet together with Fingolimod can possibly result in an interaction, they can be taken together if prescribed by your doctor. However, consult your doctor immediately if you experience lightheadedness, fainting, shortness of breath, chest pain, or heart palpitations. Do not stop using any medicines without consulting a doctor.
How does the drug interact with Promigra F 20mg/10mg Tablet:
Using Promigra F 20mg/10mg Tablet and verapamil together may lead to increased side effects.

How to manage the interaction:
Although taking Promigra F 20mg/10mg Tablet together with Verapamil can result in an interaction, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience fatigue, headache, fainting, swelling of the extremities, weight gain, shortness of breath, chest pain, increased or decreased heartbeat, or irregular heartbeat. Do not stop taking any medication without consulting a doctor.
How does the drug interact with Promigra F 20mg/10mg Tablet:
Taking Promigra F 20mg/10mg Tablet and disopyramide together can enhance the effects of disopyramide.

How to manage the interaction:
Although there may be an interaction, disopyramide can be taken with Promigra F 20mg/10mg Tablet if prescribed by your doctor. However, consult your doctor if you experience dizziness, fainting, palpitations, or slow or fast heart rate, consult your doctor immediately. Do not stop using any medications without consulting your doctor.
How does the drug interact with Promigra F 20mg/10mg Tablet:
Using Promigra F 20mg/10mg Tablet and salbutamol together can reduce the effects or increase the risk of narrowing of the airways.

How to manage the interaction:
The combined use of Promigra F 20mg/10mg Tablet and salbutamol can lead to an interaction, but they can be taken if advised by your doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Promigra F 20mg/10mg Tablet:
Using Promigra F 20mg/10mg Tablet together with terbutaline may reduce the benefits of both medications, since they have opposing effects in the body. In addition, Promigra F 20mg/10mg Tablet can sometimes cause breathing problems.

How to manage the interaction:
Although taking Promigra F 20mg/10mg Tablet together with Terbutaline can possibly result in an interaction, they can be taken together if prescribed by your doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
PropranololIsoetarine
Severe
How does the drug interact with Promigra F 20mg/10mg Tablet:
Using Promigra F 20mg/10mg Tablet together with isoetharine may reduce the benefits of both medications, since they have opposing effects in the body. In addition, Promigra F 20mg/10mg Tablet can sometimes cause breathing problems.

How to manage the interaction:
Although taking Promigra F 20mg/10mg Tablet together with Isoetarine can possibly result in an interaction, they can be taken together if prescribed by your doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
PropranololBitolterol
Severe
How does the drug interact with Promigra F 20mg/10mg Tablet:
Using Promigra F 20mg/10mg Tablet together with bitolterol may reduce the benefits of both medications, since they have opposing effects in the body. In addition, Promigra F 20mg/10mg Tablet can sometimes cause breathing problems.

How to manage the interaction:
Taking Promigra F 20mg/10mg Tablet with Bitolterol together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
PropranololIobenguane (131i)
Severe
How does the drug interact with Promigra F 20mg/10mg Tablet:
Coadministration of iobenguane (131i) and Promigra F 20mg/10mg Tablet may interfere with the effects of iobenguane I-131 in treating your condition.

How to manage the interaction:
Although there is a possible interaction between Promigra F 20mg/10mg Tablet and Iobenguane (131i), you can take these medicines together if prescribed by your doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Promigra F 20mg/10mg Tablet:
Combining ceritinib with Promigra F 20mg/10mg Tablet can decrease heart rate and increase the risk of an irregular heart rhythm.

How to manage the interaction:
Although taking Posaconazole together with Ceritinib can possibly result in an interaction, they can be taken together if prescribed by your doctor. However, consult your doctor if you experience lightheadedness, generalized weakness, dizziness, or shortness of breath, consult a doctor immediately. Do not stop using any medications consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Avoid chocolates, junk food, cheese, processed food, alcohol, and smoking. Instead, eat a healthy diet and do regular exercise to avoid weight gain caused due to Promigra F 20mg/10mg Tablet.
  • Avoid loud music, extreme temperatures, bright lights, and noisy places as it can increase headache.
  • You can try increasing your mindfulness by doing yoga, meditation, mindfulness-based cognitive therapy, and stress reduction techniques.
  • Drink enough water to stay hydrated and limit or avoid alcohol and caffeine to relieve headaches.
  • Include a diet rich in whole grains, vegetables, and fruits. This is a healthier option than eating a lot of simple carbohydrates found in processed foods.
  • You can include antioxidants in your daily diet like ashwagandha, omega-3 fatty acids, green tea, and lemon balm.
  • Try to spend time with your friends and family. Having a strong social network may help you lower your risk of anxiety.

Habit Forming

No

Therapeutic Class

ANTIMIGRAINE AGENTS
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Alcohol

Unsafe

You are recommended to avoid alcohol consumption while taking Promigra F 20mg/10mg Tablet. Alcohol intake, along with Promigra F 20mg/10mg Tablet, may cause increased dizziness and drowsiness.

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Pregnancy

Caution

Please consult your doctor if you are pregnant or planning to conceive before using Promigra F 20mg/10mg Tablet.

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Breast Feeding

Caution

Please consult your doctor before taking Promigra F 20mg/10mg Tablet if you are a lactating mother.

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Driving

Caution

Promigra F 20mg/10mg Tablet may make you feel drowsy. Do not drive or operate machinery if you experience drowsiness.

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Liver

Caution

Therapy with propranolol should be administered cautiously in patients with liver disease. Please consult your doctor if you have a history of liver impairment/liver disease.

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Kidney

Caution

Plasma clearance of Propranolol in Promigra F 20mg/10mg Tablet is reduced in patients with renal failure. Please consult your doctor if you have a history of kidney impairment/kidney disease.

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Children

Safe if prescribed

Promigra F 20mg/10mg Tablet is safe to use for children below 12 years of age when prescribed by the doctor.

Have a query?

FAQs

Promigra F 20mg/10mg Tablet belongs to the class of anti-migraine drugs used to treat migraine.

Promigra F 20mg/10mg Tablet is a combination of two drugs: Propranolol and Flunarizine. Promigra F 20mg/10mg Tablet treats migraine by reducing the blood flow to the brain, and inhibits cortical spreading depression, electrical activity in the brain that causes pain and inflammation.

Promigra F 20mg/10mg Tablet may sometimes cause weight gain during its prolonged use. It is always advised to maintain a well-balanced, healthy diet and exercise regularly.

Promigra F 20mg/10mg Tablet does not work for a sudden migraine attack. It is helpful in only preventing new episodes of migraine headaches. Please let your doctor know if you have sudden attacks to be prescribed other suitable medications.

Promigra F 20mg/10mg Tablet is contraindicated in asthma, slow heart rate, abnormal heart rhythms, heart conditions like AV (Atrioventricular) block or sick sinus syndrome, depression, and Parkinson's disease. Please consult your doctor before starting Promigra F 20mg/10mg Tablet if you have a medical history.

Your doctor will prescribe Promigra F 20mg/10mg Tablet to prevent any new episodes of migraine. Please do not stop taking this medicine unless advised by your doctor since it may lead to recurrent episodes of migraine. Promigra F 20mg/10mg Tablet also contains Propranolol, and its sudden withdrawal may cause sweating, shaking, irregular heartbeat, and worsening of underlying angina or heart attack. Hence, do not stop using Promigra F 20mg/10mg Tablet unless advised by your doctor.

Promigra F 20mg/10mg Tablet may cause sleepiness in some individuals as a potential side effect. If this occurs, exercise caution and avoid activities that require mental alertness, such as driving or operating heavy machinery.

Store Promigra F 20mg/10mg Tablet at room temperature in a cool and dry place, away from sunlight and moisture. Keep out of reach of children.

The common side effects of Promigra F 20mg/10mg Tablet are weight gain, slow heart rate, tiredness, depression, drowsiness, abnormal dreams, and cold extremities (hands and feet). Please consult your doctor if any of these side effects persist or worsen.

Country of origin

India
Other Info - PR77677

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