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  3. Prologem 50 Tablet 10's

Prologem 50 Tablet 10's, Pack of 10 TABLETS
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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Prologem 50 Tablet is used to treat high blood pressure (hypertension), heart-related chest pain (angina), irregular heart rhythm (arrhythmia), and to protect the heart after a heart attack (myocardial infarction). Besides this, it may also help in relieving symptoms of migraine-related headache and tremors (fits). It contains Metoprolol, which helps in slowing down the heart rate, making it easier for the heart to pump blood throughout the body. This lowers the blood pressure and helps in reducing the risk of having a stroke, heart attack, or other heart or kidney problems in the future. In some cases, it may cause certain common side effects like dizziness, tiredness, diarrhoea, stomach pain, nausea, and headache. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Composition :

METOPROLOL-50MG

Manufacturer/Marketer :

Genetech Healthcare

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

NPPA :

Regulated

About Prologem 50 Tablet

Prologem 50 Tablet is used in the treatment of high blood pressure (hypertension), heart-related chest pain (angina), and irregular heart rhythm (arrhythmia). Hypertension is a lifelong or chronic condition in which the force exerted by the blood against the artery walls becomes so high that it leads to heart disease.

Prologem 50 Tablet contains 'Metoprolol', which helps in slowing down the heart rate, making it easier for the heart to pump blood throughout the body. 

Not everyone who is taking Prologem 50 Tablet will get these side effects. In some cases, Prologem 50 Tablet may cause certain common side effects like dizziness, tiredness, diarrhoea, stomach pain, nausea, and headache. Most of these side effects do not require medical attention and resolve gradually over time. However, if the side effects are persistent, reach out to your doctor.

You can take Prologem 50 Tablet with food or without food. It should be swallowed as a whole with a glass of water. Do not chew, bite, crush, or break it. Your doctor will advise you on how often you should take your tablets based on your medical condition. It is always important to complete your treatment course for better results.

Inform your doctor if you are allergic to Prologem 50 Tablet . Also, let your doctor know if you have low blood pressure, asthma, overactive thyroid, metabolic acidosis, or severe blood circulation problems. Consult your doctor before taking Prologem 50 Tablet if you are pregnant or breastfeeding. Prologem 50 Tablet is not recommended for use in children. Prologem 50 Tablet may cause dizziness, so drive with caution.

Uses of Prologem 50 Tablet

Prologem 50 Tablet is used in the treatment of High blood pressure (hypertension), prevention of heart-related chest pain (angina), heart rhythm disorder (arrhythmia), and heart attack (myocardial infarction). The detailed uses of Prologem 50 Tablet are as follows:<br/>

  • Treatment of Hypertension: Prologem 50 Tablet controls high blood pressure by reducing the heart rate and the force of contraction, thereby lowering blood pressure.<br/> 
  • Prevention of Heart-related Chest Pain: Prologem 50 Tablet prevents chest pain (angina) by reducing the workload on the heart and improving blood flow to the heart muscle.<br/>
  • Control of Abnormal Heart Rhythms: Prologem 50 Tablet helps manage irregular heartbeats (arrhythmias) by slowing the heart rate and stabilizing the heart's rhythm, reducing symptoms and improving heart function.<br/>
  • Management of Heart Attack: Prologem 50 Tablet is used to manage heart attack (myocardial infarction) by reducing the workload on the heart and preventing further damage.<br/>

Directions for Use

• Prologem 50 Tablet should be taken with or immediately after a meal for better absorption. • It is usually taken 2-3 times daily at the same time each day or as prescribed by your doctor. • Swallow Prologem 50 Tablet as a whole with a glass of water. • Do not crush, chew, open, or break it.

Medicinal Benefits

  • Prologem 50 Tablet  helps in slowing down the heart rate, making it easier for the heart to pump blood throughout the body.
  • This medicine lowers the blood pressure and helps in reducing the risk of having a stroke, heart attack, or other heart or kidney problems in the future.
  • Prologem 50 Tablet may also help in relieving symptoms of migraine-related headache and tremors (fits).

How Prologem 50 Tablet Works

Prologem 50 Tablet contains 'Metoprolol', which helps in slowing down the heart rate, making it easier for the heart to pump blood throughout the body. This lowers the blood pressure and helps in reducing the risk of having a stroke, heart attack, or other heart or kidney problems in the future.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Prologem 50 Tablet
  • Reducing the amount of time you spend outside and indoors in the cold.
  • keeping your hands warm by donning mittens, gloves, or other protective clothing.
  • Observing a skincare regimen that safeguards your fingers and hands.
  • To improve circulation, give your hands and feet a little massage.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
Here are the seven steps to manage medication-triggered Dyspnea (Difficulty Breathing or Shortness of Breath):
  • Tell your doctor immediately if you experience shortness of breath after taking medication.
  • Your doctor may adjust the medication regimen or dosage or give alternative medical procedures to minimize the symptoms of shortness of breath.
  • Monitor your oxygen levels and breathing rate regularly to track changes and potential side effects.
  • For controlling stress and anxiety, try relaxation techniques like deep breathing exercises, meditation, or yoga.
  • Make lifestyle changes, such as quitting smoking, exercising regularly, and maintaining a healthy weight.
  • Seek emergency medical attention if you experience severe shortness of breath, chest pain, or difficulty speaking.
  • Follow up regularly with your doctor to monitor progress, adjust treatment plans, and address any concerns or questions.
Here are the few steps for dealing with itching caused by drug use:
  • Report the itching to your doctor immediately; they may need to change your medication or dosage.
  • Use a cool, damp cloth on the itchy area to help soothe and calm the skin, reducing itching and inflammation.
  • Keep your skin hydrated and healthy with gentle, fragrance-free moisturizers.
  • Try not to scratch, as this can worsen the itching and irritate your skin.
  • If your doctor prescribes, you can take oral medications or apply topical creams or ointments to help relieve itching.
  • Track your itching symptoms and follow your doctor's guidance to adjust your treatment plan if needed. If the itching persists, consult your doctor for further advice.

What if I have taken an overdose of Prologem 50 Tablet

Do not take more than the prescribed dose of Prologem 50 Tablet as it may cause overdose. The symptoms of overdose include slow heart rate, difficulty breathing, trembling or dizziness. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

  • Do not take Prologem 50 Tablet if you are allergic to Prologem 50 Tablet or any other beta-blockers.
  • Avoid taking Prologem 50 Tablet if you have/had heart conduction, rhythm problems, uncontrolled/severe heart failure, blocked blood vessels, blood circulation problems, untreated pheochromocytoma, metabolic acidosis, low blood pressure, or prinzmetal angina.
  • Inform your doctor if you have asthma, COPD, diabetes, blood vessel disorder, slow heart rate, pheochromocytoma, myasthenia gravis, dry eye problems, kidney or liver impairment; if you are taking anti-depressants, other blood pressure-lowering medicines, or anti-arrhythmic agents.
  • Consult your doctor before taking Prologem 50 Tablet if you are pregnant or breastfeeding.
  • Prologem 50 Tablet is not recommended for children as safety and efficacy have not been established.
  • Prologem 50 Tablet may cause dizziness, so drive with caution.
  • Don't stop taking Prologem 50 Tablet without consulting your doctor. Suddenly stopping the use of Prologem 50 Tablet may cause changes in your heart rhythm and blood pressure, cause chest pain, or a heart attack. Your doctor will gradually lower your dose to help prevent these symptoms.

Drug-Drug Interactions

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MetoprololAminophylline
Severe
MetoprololElvitegravir
Severe

Drug-Drug Interactions

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MetoprololAminophylline
Severe
How does the drug interact with Prologem 50 Tablet:
Coadministration of Aminophylline with Prologem 50 Tablet together can make Prologem 50 Tablet less effective and increase the effects of aminophylline.

How to manage the interaction:
Taking Aminophylline with Prologem 50 Tablet may lead to an interaction, it can be taken only if a doctor has advised it. If you experience nausea, vomiting, sleeplessness, restlessness, irregular heartbeats, or difficulty in breathing, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
MetoprololElvitegravir
Severe
How does the drug interact with Prologem 50 Tablet:
Taking elvitegravir may increase the metabolism of Prologem 50 Tablet.

How to manage the interaction:
Although there may be an interaction, Prologem 50 Tablet can be taken with Elvitegravir if prescribed by the doctor. Consult the doctor if you experience dizziness, palpitations, fainting, slow or fast pulse, or irregular heartbeats. Do not discontinue any medications without talking to your doctor.
MetoprololSaquinavir
Severe
How does the drug interact with Prologem 50 Tablet:
Using Prologem 50 Tablet and Saquinavir can increase the risk of an irregular heart rhythm.

How to manage the interaction:
There may be a possible interaction between Prologem 50 Tablet and Saquinavir, but they can be taken together if your doctor has prescribed them. However, consult a doctor immediately if you experience dizziness, lightheadedness, fainting, slow pulse, or irregular heartbeat. Do not discontinue any medications without consulting a doctor.
MetoprololCeritinib
Severe
How does the drug interact with Prologem 50 Tablet:
Taking ceritinib together with Prologem 50 Tablet can slow your heart rate and increase the risk of an irregular heart rhythm.

How to manage the interaction:
Although there is a interaction between Prologem 50 Tablet and Ceritinib, but they can be taken together if your doctor has prescribed them. However, consult your doctor immediately if you experience any dizziness, lightheadedness, fainting, or irregular heartbeat. Do not discontinue any medications without consulting a doctor.
MetoprololClonidine
Severe
How does the drug interact with Prologem 50 Tablet:
Co-administration of Clonidine and Prologem 50 Tablet may lower blood pressure and slow the heart rate.

How to manage the interaction:
Although there is a possible interaction between Clonidine and Prologem 50 Tablet, you can take these medicines together if prescribed by your doctor. However, if you experience headaches, slow heartbeat, dizziness, or feeling like you might pass out, contact your doctor. Do not stop using any medications without first talking to your doctor.
MetoprololArtemether
Severe
How does the drug interact with Prologem 50 Tablet:
Both Prologem 50 Tablet and Artemether may increase the blood levels and effects of Prologem 50 Tablet activity.

How to manage the interaction:
Taking Prologem 50 Tablet and Artemether together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience blurry vision, confusion, dizziness, fainting, lightheadedness, nausea or vomiting, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
MetoprololDisopyramide
Severe
How does the drug interact with Prologem 50 Tablet:
Combine use of Prologem 50 Tablet with Disopyramide may increase the effectiveness of Disopyramide.

How to manage the interaction:
Although there may be an interaction, Prologem 50 Tablet can be taken with Disopyramide if prescribed by the doctor. Consult the doctor if you experience any symptoms such as dizziness, palpitations, fainting, slow or fast pulse, or irregular heartbeats. Do not discontinue any medication without a doctor's advice.
MetoprololVerapamil
Severe
How does the drug interact with Prologem 50 Tablet:
Coadministration of Prologem 50 Tablet with Verapamil may lead to increased side effects.

How to manage the interaction:
Although there may be an interaction, Prologem 50 Tablet can be taken with Verapamil if prescribed by the doctor. Consult a prescriber if you experience fatigue, headache, fainting, swelling of the extremities, weight gain, shortness of breath, chest pain, increased or decreased heartbeat, or irregular heartbeat. Do not discontinue any medications without a doctor's advice.
MetoprololAcebutolol
Severe
How does the drug interact with Prologem 50 Tablet:
Coadministration of Acebutolol with Prologem 50 Tablet can cause abnormal heart rhythm.

How to manage the interaction:
Taking Prologem 50 Tablet and Acebutolol together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience blurry vision, confusion, dizziness, fainting, lightheadedness, nausea or vomiting, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
MetoprololTizanidine
Severe
How does the drug interact with Prologem 50 Tablet:
Coadministration of Prologem 50 Tablet and Tizanidine may reduce the efficiency of Prologem 50 Tablet.

How to manage the interaction:
Taking Prologem 50 Tablet and Tizanidine together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience blurry vision, confusion, dizziness, fainting, lightheadedness, nausea or vomiting, contact your doctor immediately. do not discontinue any medications without talking to your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Do regular physical activity or exercise.
  • Opt for a diet rich in whole grains, fruits, vegetables, and low-fat dairy products.
  • Limit intake of sodium chloride (table salt) in your daily diet.
  • Quitting smoking is the best strategy to lower the risk of heart disease.
  • Avoid chronic stress as it can raise your blood pressure. 
  • Try to enjoy and spend time with your loved ones to cope with stress and practice mindfulness techniques.
  • Try to include heart-healthy omega-3 fatty acid-containing food drinks in your daily diet. You can also use low-fat cooking oil like olive oil, soybean oil, canola oil, and coconut oil.

Habit Forming

No

Therapeutic Class

ANTI- HYPERTENSIVES

Prologem 50 Tablet Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Unsafe

Alcohol might increase the blood pressure-lowering effect of Prologem 50 Tablet . It might also cause increased dizziness. Therefore, avoid alcohol consumption while taking Prologem 50 Tablet .

bannner image

Pregnancy

Unsafe

Prologem 50 Tablet is not recommended for use during pregnancy. If you are pregnant or planning for pregnancy, consult your doctor.

bannner image

Breast Feeding

Consult your doctor

Prologem 50 Tablet may pass into breastmilk. Consult a doctor before taking Prologem 50 Tablet if you are breastfeeding.

bannner image

Driving

Caution

Prologem 50 Tablet may cause dizziness and tiredness. Therefore, drive or operate machinery only if you are alert.

bannner image

Liver

Consult your doctor

Dose adjustment may be needed. Consult your doctor before taking Prologem 50 Tablet if you have a liver impairment or any concerns regarding this.

bannner image

Kidney

Consult your doctor

Dose adjustment may be needed. Consult your doctor before taking Prologem 50 Tablet if you have kidney impairment or any concerns regarding this.

bannner image

Children

Unsafe

Prologem 50 Tablet is not recommended in children as the safety and efficacy have not been established.

Have a query?

FAQs

Prologem 50 Tablet is indicated in the treatment of high blood pressure (hypertension), prevention of heart-related chest pain (angina), heart rhythm disorder (arrhythmia), and heart attack (myocardial infarction).

Prologem 50 Tablet helps in slowing down the heart rate, making it easier for the heart to pump blood throughout the body. Thereby, lowers blood pressure.

Do not stop taking Prologem 50 Tablet without consulting your doctor as it may lead to a rise in blood pressure. To treat your condition effectually, continue taking Prologem 50 Tablet for as long as your doctor has prescribed it to you. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Prologem 50 Tablet .

Consult your doctor before taking Prologem 50 Tablet if you have hyperthyroidism (overactive thyroid) as it might mask the symptoms or make it difficult to recognise the signs of thyrotoxicosis (excess thyroid hormone in the body).

Consult your doctor before taking Prologem 50 Tablet with anti-diabetic medicines as it might mask the signs of low blood sugar. Regular monitoring of blood glucose levels while taking Prologem 50 Tablet is advised.

Your doctor may probably ask you to stop taking Prologem 50 Tablet 24hours prior to the surgery, as it might lower blood pressure when combined with general anaesthesia. If you are due to have any surgery or are receiving an anaesthetic, inform the doctor that you are taking Prologem 50 Tablet .

Taking Prologem 50 Tablet along with multivitamin/multimineral supplements may decrease the effect of Prologem 50 Tablet . Therefore, maintain a gap of at least 2 hours between both. However, you are advised to take Prologem 50 Tablet with other medicines only after consulting your doctor.

High blood pressure increases the workload on the arteries and heart. If untreated, it could damage the blood vessels of the heart, brain, and kidney and might result in stroke, heart failure or kidney failure. Hypertension increases the risk of heart attacks. Therefore, anti-hypertensives such as Prologem 50 Tablet are used to lower the blood pressure to normal; this reduces the risk of developing these disorders.

Yes, Prologem 50 Tablet contains metoprolol which belongs to a group of medicines called beta-blockers.

No, Prologem 50 Tablet is not a blood thinner. It is an antihypertensive medicine.

Prologem 50 Tablet starts working within 2 hours. However, it can take up to a week to show its full effect.

No, it is not dangerous to take Prologem 50 Tablet . It is safe to take Prologem 50 Tablet if prescribed by the doctor.

Prologem 50 Tablet may cause sleepiness. Drive or operate machinery only if you are alert. Consult the doctor if you have sleep problems.

Alcohol might increase the blood pressure-lowering effect of Prologem 50 Tablet . It might also cause increased dizziness. Therefore, avoid alcohol consumption while taking Prologem 50 Tablet .

Prologem 50 Tablet may cause side effects like dizziness, tiredness, diarrhoea, stomach pain, nausea, and headache. If the side effects are persistent, reach out to your doctor.

Country of origin

India

Manufacturer/Marketer address

Unit 3 Enterprise Business Centre Consul Avenue Rainham Essex RM13 8JE, United Kingdom
Other Info - PRO2021

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While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 29, 2025 | 8:39 AM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Reference

  1. https://www.drugs.com/metoprolol.html
  2. https://www.nhs.uk/medicines/metoprolol/
  3. https://www.medicines.org.uk/emc/files/pil.5816.pdf
  4. https://www.accessdata.fda.gov/drugsatfda_docs/label/2006/019962s032lbl.pdf

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