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compositionComposition:FUROSEMIDE-10MG
prescription
Prescription Medicine
info
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Prolix 10 Injection 2 ml belongs to the class of loop diuretics. It is used in the treatment of Oedema (swelling) and hypertension (high blood pressure). This medicine contains furosemide, which works by reducing the excess fluid levels in the body and thus reduces swelling. Common side effects include frequent urination, feeling thirsty, dry mouth, headache, nausea or vomiting, headache, confusion and dizziness.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Veda Maddala , M Pharmacy
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More about the Product

Composition :

FUROSEMIDE-10MG

Manufacturer/Marketer :

Themis Pharmaceutical Ltd

Consume Type :

Parenteral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Prolix 10 Injection 2 ml

Prolix 10 Injection 2 ml is an injection used to treat fluid buildup in the body, also known as edema, which is caused by conditions like heart failure, liver disease, or kidney disease. It is also used to treat very high blood pressure when a rapid response is needed.

Because this medicine is given as an injection, a healthcare professional will usually decide how often you need it based on your body's response. When receiving this treatment, cutting down on salt in your diet and keeping track of your daily fluid intake can help improve your results.

While using Prolix 10 Injection 2 ml, you might experience mild side effects like dehydration, dizziness, or a dry mouth. However, you must contact your doctor immediately if you experience severe symptoms like muscle cramps, extreme weakness, or a sudden loss of hearing.

Before starting this medicine, tell your doctor if you have severe kidney problems, gout, or diabetes. Do not take this if you are unable to pass urine or have a known severe allergy to similar liquid medicines.

This medicine can interact with other drugs like blood pressure pills or certain antibiotics, and drinking alcohol can increase your risk of dizziness. If you are pregnant, breastfeeding, or elderly, you should consult your healthcare provider before receiving this injection.

Uses of Prolix 10 Injection 2 ml

Your doctor may prescribe Prolix 10 Injection 2 ml to treat the following conditions:

  • Fluid overload (Edema): Helps clear excess fluid trapped in body tissues (like the lungs, legs, or abdomen) caused by heart failure, liver scarring, or kidney issues.
  • High blood pressure emergencies: Lowers dangerously high blood pressure quickly to reduce the workload on your heart and blood vessels.

Key Benefits

Prolix 10 Injection 2 ml helps remove excess fluid from the body, reducing swelling and easing symptoms caused by fluid retention. It also helps lower high blood pressure, reducing strain on the heart and blood vessels. When used as prescribed, it supports better symptom control and improves overall quality of life. Key benefits include:

  • Reduces Fluid Retention: Helps remove excess salt and water from the body, relieving swelling in the feet, ankles, legs, and other affected areas.
  • Improves Breathing: By reducing fluid buildup in the lungs, it helps relieve breathlessness and improves comfort in people with conditions such as heart failure.
  • Lowers High Blood Pressure: Helps reduce blood pressure, lowering the risk of complications such as heart attack, stroke, and kidney damage.
  • Relieves Swelling and Discomfort: Helps ease the heaviness, tightness, and discomfort associated with oedema, making everyday movements more comfortable.
  • Supports Heart and Kidney Health: By reducing excess fluid and controlling blood pressure, it helps decrease the workload on the heart and supports long-term cardiovascular and kidney health.
Side effects of Prolix 10 Injection 2 ml
  • Consume controlled amounts of salt to raise sodium levels.
  • Eat fresh fruits like apples, berries, oranges, mangoes, and bananas.
  • Include fresh vegetables like broccoli, sweet potatoes, beets, okra, spinach, peppers, carrots, and edamame.
  • Choose frozen vegetables without added butter or sauce.
  • Drink electrolyte beverages like sports drinks or electrolyte solutions to replenish sodium and other electrolytes.
  • Avoid excessive salt intake, but allow for controlled increases as needed.
  • Monitor and manage underlying health conditions that may contribute to hyponatremia.
  • Let your doctor know if you experience symptoms such as fatigue, weakness, muscle cramps, or respiratory depression. Hyperchloremia may cause these.
  • Hyperchloremia is a condition in which the blood has an excessive level of chloride ions, which can disrupt the body's acid-base balance and lead to various complications.
  • Your doctor will thoroughly evaluate to determine if your medication is causing the hyperchloremia.
  • If your medication is found to be the cause, your doctor may adjust your medication regimen or switch you to alternative medicines.
  • To manage hyperchloremia, focus on consuming a balanced diet that is low in chloride-rich foods. Include potassium-rich foods like bananas, leafy greens, and sweet potatoes to help balance electrolyte levels.
  • Adopting a healthy lifestyle can help manage your condition. Aim for regular physical activity, stress-reducing techniques, and adequate sleep to help your body recover.
  • Regular monitoring and follow-ups with your doctor are crucial to managing your condition. Schedule check-ups as recommended by your doctor to monitor your symptoms and adjust your treatment plan as needed.
  • Talk to your doctor about oral potassium supplements.
  • Eat potassium rich foods such as bananas, avocados, oranges, dark leafy greens, beans and peas, fish, spinach, milk and tomatoes.
  • Drink plenty of water to eliminate uric acid.
  • Avoid purine-rich foods such as red meat, organ meats, certain seafood (sardines, anchovies) and too much alcohol.
  • Regularly do low impact exercises like swimming or walking.
  • To reduce pain and swelling, apply ice packs to the affected area.
  • Take rest and avoid activities that strain the affected joint.
  • Elevate the affected joint to encourage fluid drainage.
  • Aim for weight loss and maintain a healthy body weight to reduce the risk of gout.

Directions for Use

  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safe and effective use.
  • Prolix 10 Injection 2 ml will be administered by the doctor or healthcare professional.
  • Do not self-administer.

How Prolix 10 Injection 2 ml Works

Prolix 10 Injection 2 ml is a type of medicine that helps your kidneys get rid of extra salt and water. It does this by acting on specific parts of your kidneys to prevent them from holding onto sodium, chloride, and water. Instead of keeping these substances in your blood, your kidneys filter them out into your urine. Because it is given as an injection directly into a vein or muscle, it bypasses your digestive system. This allows the medicine to start working within minutes, causing a rapid increase in urination, which quickly relieves pressure in your blood vessels and reduces swelling throughout your body.
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Alcohol

Unsafe

Avoid alcohol intake while on treatment with Prolix 10 Injection 2 ml as it may cause excessive lowering of blood pressure.

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Pregnancy

Caution

Prolix 10 Injection 2 ml should not be used during pregnancy unless clearly necessary. So, inform your doctor if you are pregnant or suspect pregnancy. Your doctor will weigh the benefits and potential risks before prescribing Prolix 10 Injection 2 ml.

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Breast Feeding

Unsafe

Prolix 10 Injection 2 ml passes into breast milk and may inhibit the secretion of milk. Therefore it is not recommended for breastfeeding women.

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Driving

Caution

Prolix 10 Injection 2 ml may cause dizziness; thus, avoid driving or using machinery unless you are alert.

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Liver

Caution

Notify your doctor if you have a history of liver diseases/conditions. Your doctor may adjust your dose accordingly.

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Kidney

Caution

Notify your doctor if you have a history of kidney diseases/conditions. Your doctor may adjust your dose accordingly.

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Children

Caution

Please consult your doctor. Prolix 10 Injection 2 ml is recommended for adolescents and children under the age of 15 only in exceptional cases.

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Heart

Caution

Inform your doctor if you have heart disease. Your doctor may adjust your dose depending upon your heart condition.

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Geriatrics

Caution

Prolix 10 Injection 2 ml should be used with caution in elderly patients. Please consult your doctor before use.

What if I have taken an overdose of Prolix 10 Injection 2 ml

If you receive too much of this medicine, you may experience severe dizziness, fainting, extreme weakness, or confusion due to rapid fluid loss. Seek emergency medical attention immediately if an overdose is suspected.

Diet & Lifestyle Advise

  • Limit your sodium intake: Avoid high-salt foods like processed meats, canned soups, and salty snacks, as salt causes your body to hold onto water, working against the medicine.
  • Monitor your daily weight: Weigh yourself at the same time each morning. A sudden, unexpected weight gain (such as 2 to 3 pounds in a single day) could mean your body is retaining fluid again.
  • Stay hydrated safely: Talk to your doctor about how much liquid you should drink each day, especially if you have heart or kidney issues, as drinking too much or too little can be dangerous.
  • Eat potassium-rich foods: Since this medicine can lower potassium levels, your doctor may suggest eating foods like bananas, spinach, or potatoes, or taking a potassium supplement.
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How Soon It Starts Working

The time required for Prolix 10 Injection 2 ml to start to work: Prolix 10 Injection 2 ml ideally shows its action within 30 minutes of intramuscular and 5 minutes of intravenous administration of the dose. The time for which the effects of Prolix 10 Injection 2 ml last: The effect of Prolix 10 Injection 2 ml lasts for 2 hours.

What if you forget to take Prolix 10 Injection 2 ml

If you receive this injection at a clinic and miss an appointment, contact your healthcare provider right away to reschedule. If you are injecting it at home and miss a scheduled time, inject it as soon as you remember. However, if it is almost time for your next injection, skip the missed dose and resume your regular schedule. Do not double the dose to make up for a missed one.

Storage

• Store Prolix 10 Injection 2 ml injections at room temperature, ideally between 20°C and 25°C (68°F to 77°F).

Drug Warnings

  • Inspect the injection before use: Ensure the solution is clear, colourless, and free from visible particles before administration. Do not use the medicine if it appears cloudy, discoloured, or contains sediment.
  • Rotate injection sites: If you are administering the injection at home, use a different injection site with each dose to help reduce skin irritation, bruising, and tissue damage.
  • Never reuse needles or syringes: Always use a new sterile needle and syringe for each injection, and dispose of used sharps safely in an approved sharps container.
  • Rise slowly after treatment: This medicine may cause dizziness or light-headedness, particularly when standing up. Get up slowly from a sitting or lying position to help reduce the risk of falls.
  • Attend regular monitoring: Keep all scheduled appointments so your doctor can monitor your blood pressure, kidney function, electrolyte levels (such as potassium and sodium), and your response to treatment.

Drug-Drug Interactions

verifiedApollotooltip
  • Aminoglycoside antibiotics (such as gentamicin): Using these medicines together may increase the risk of hearing damage (ototoxicity) and kidney injury.
  • Blood pressure-lowering medicines: Combining Prolix 10 Injection 2 ml with antihypertensive drugs may cause an excessive drop in blood pressure, leading to dizziness or fainting.
  • Lithium: Prolix 10 Injection 2 ml can reduce the elimination of lithium, increasing the risk of lithium toxicity. Close monitoring or dose adjustment may be required.
  • NSAIDs (such as ibuprofen or naproxen): These medicines may reduce the diuretic effect of Prolix 10 Injection 2 ml and increase the risk of kidney damage, particularly in people who are dehydrated or have kidney disease.
FurosemideZiprasidone
Critical
FurosemideTobramycin
Severe

Drug-Drug Interactions

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FurosemideZiprasidone
Critical
How does the drug interact with Prolix 10 Injection 2 ml:
Taking Ziprasidone with Prolix 10 Injection 2 ml can increase the risk of abnormal heart rhythm.

How to manage the interaction:
Taking Ziprasidone with Prolix 10 Injection 2 ml is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, weakness, tiredness, drowsiness, confusion, muscle pain, cramps, dizziness, nausea, or vomiting. Do not discontinue any medications without consulting a doctor.
FurosemideTobramycin
Severe
How does the drug interact with Prolix 10 Injection 2 ml:
Taking Prolix 10 Injection 2 ml with Tobramycin can increase the risk of hearing loss and kidney problems.

How to manage the interaction:
Although there is a possible interaction between Tobramycin and Prolix 10 Injection 2 ml, you can take these medicines together if prescribed by your doctor. Do not discontinue any medications without consulting your doctor.
FurosemideStreptomycin
Severe
How does the drug interact with Prolix 10 Injection 2 ml:
Coadministration of Streptomycin and Prolix 10 Injection 2 ml may increase the risk or severity of hearing or kidney problems.

How to manage the interaction:
There may be a possibility of interaction between Streptomycin and Prolix 10 Injection 2 ml, but it can be taken if prescribed by a doctor. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, hearing difficulty, swelling, body aches, increased or decreased urination, or memory loss, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
FurosemideAmikacin
Severe
How does the drug interact with Prolix 10 Injection 2 ml:
Coadministration of Amikacin with Prolix 10 Injection 2 ml can increase the risk of developing kidney disorder and other side effects.

How to manage the interaction:
Although taking amikacin and Prolix 10 Injection 2 ml together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience ringing in the ears, irregular urination, muscle cramps, vomiting, or weakness, consult the doctor. Do not discontinue any medications without a doctor's advice.
FurosemideTizanidine
Severe
How does the drug interact with Prolix 10 Injection 2 ml:
Combining Tizanidine and Prolix 10 Injection 2 ml can lower your blood pressure.

How to manage the interaction:
Taking Tizanidine and Prolix 10 Injection 2 ml together can lead to an interaction, but it can be taken if your doctor advises. However, if you experience any symptoms like headache, dizziness, lightheadedness, fainting, and changes in pulse or heart rate, contact your doctor immediately. Avoid driving or operating hazardous machinery until you know how the medications affect you, use caution when getting up from a sitting or lying position, and do not discontinue any medications without consulting your doctor.
FurosemideGlimepiride
Severe
How does the drug interact with Prolix 10 Injection 2 ml:
Co-administration of Prolix 10 Injection 2 ml may interfere with blood glucose control and lower the effectiveness of Glimepiride.

How to manage the interaction:
Although there is a possible interaction, glimepiride can be taken with Prolix 10 Injection 2 ml if prescribed by the doctor. Regular monitoring of blood glucose levels is advised. Do not discontinue the medications without consulting a doctor.
FurosemideDiclofenac
Severe
How does the drug interact with Prolix 10 Injection 2 ml:
Concomitant administration of diclofenac and Prolix 10 Injection 2 ml may decrease the therapeutic efficacy of Prolix 10 Injection 2 ml and adversely affect renal function.

How to manage the interaction:
There may be a possible interaction between diclofenac and Prolix 10 Injection 2 ml, but they can be taken together if your doctor has prescribed them. However, consult your doctor immediately if you experience symptoms like nausea, dizziness, irregular heartbeats, altered blood pressure, tingling. Do not stop using any medications without first talking to your doctor.

Drug-Food Interactions

verifiedApollotooltip
  • High-sodium foods: Excess salt intake can reduce the effectiveness of Prolix 10 Injection 2 ml by promoting fluid retention. Following your healthcare provider's dietary advice on sodium intake can help improve treatment outcomes.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[DIURETIC]

FAQs

Prolix 10 Injection 2 ml belongs to a group of medicines called loop diuretics used to treat oedema. It may also be used in the treatment of extremely high blood pressure that may lead to life-threatening conditions (hypertensive crisis).
Prolix 10 Injection 2 ml increases urine production to eliminate excess water (fluid retention) in the body. This reduces the fluid in the tissues, which helps in reducing swelling (oedema).
Parenteral therapy should only be used for patients unable to take oral medications or in an emergency clinical situation. Prolix 10 Injection 2 ml is prescribed by the doctor when rapid and effective removal of excess fluid is required, for patients who cannot take it orally, in an emergency or during periods of extremely high blood pressure, which may result in life-threatening conditions.
Prolix 10 Injection 2 ml is contraindicated in people with anuria (reduction or absence of urine) or a history of hypersensitivity to Furosemide.
Prolix 10 Injection 2 ml may cause weight loss as your body loses water. However, do not use Prolix 10 Injection 2 ml to lose weight. If you have any concerns regarding weight, consult your doctor.
Notify your doctor if you are taking lithium because Prolix 10 Injection 2 ml decreases lithium renal clearance and increases the risk of lithium toxicity.
Yes, this medicine helps your body get rid of water by flushing out salts, which can lead to low potassium levels in your blood. Your healthcare provider may monitor your blood work and recommend potassium supplements or dietary changes. Talk to your doctor if you experience muscle weakness or cramping.
The injection form of Prolix 10 Injection 2 ml is used when a rapid effect is needed, such as during a medical emergency, or if you are unable to take pills by mouth due to severe illness. It delivers the medicine directly into your system for immediate action. Talk to your doctor about when you can switch to the tablet form.
This medicine can cause dizziness, lightheadedness, or blurred vision, especially shortly after you receive it. You should avoid driving or operating machinery until you know how this medication affects you. Talk to your doctor if you feel dizzy or faint.
This medicine is generally not recommended during pregnancy unless your doctor decides the benefits outweigh the risks, as it can cross the placenta and affect the baby's growth. If you are pregnant or planning to become pregnant, talk to your doctor.
Ringing in the ears or temporary hearing loss can occur, especially if the injection is given too quickly or in high doses. If you notice any changes in your hearing, notify your healthcare provider immediately. Talk to your doctor about these symptoms.
It is best to avoid alcohol while using this medicine because alcohol can worsen side effects like dizziness, lightheadedness, and low blood pressure. This increases your risk of fainting or falling. Talk to your doctor if you have concerns about alcohol use.
The duration of your treatment depends entirely on the underlying medical condition causing your fluid retention and how your body responds to the therapy. Your healthcare provider will determine the appropriate treatment length. Talk to your doctor to understand your specific treatment plan.

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Reference

  1. National Health Service (NHS). Furosemide - NHS Medicines Reference Guide. London, UK: NHS; 2025. [Accessed on 02 Jun. 2026]Check here
  2. National Center for Biotechnology Information (NCBI). Furosemide Scientific Research Publication. Bethesda, MD: NLM; 2025. [Accessed on 02 Jun. 2026]Check here
  3. Electronic Medicines Compendium (EMC). Pil.7371 Patient Information Leaflet (PIL). Cheshire, UK: Datapharm; 2025. [Accessed on 02 Jun. 2026]Check here
  4. Drugs.com Clinical Review Team. Furosemide Drug Interactions Reference. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026]Check here
  5. Drugs and Lactation Database (LactMed) [Internet]. 2006. [Accessed on 19 Feb. 2020]Check here
  6. Furosemide [Drug Label]. 2019. [Accessed on 25 Jul. 2024]Check here
  7. Lasilactone 20 mg/50 mg Capsules - Summary of Product Characteristics (SmPC) - (emc) [Internet]. Medicines.org.uk. 2022 [Accessed on 27 July 2022]Check here

Country of origin

INDIA

Manufacturer/Marketer address

69-B , J-Type Area ,G.I.D.C. Industrial Estate,Near Cng Gas Station,Vapi- 396195.
Other Info - PRO2064
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